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Publications related to Bioscience (10,000)
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Poster
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Ammonia (NH3) is a transboundary pollutant, with agriculture responsible for over 90% of global NH3 emissions. In agriculture, animal houses, in-house and outdoor manure stores, and field application of manures and commercial nitrogen (N) fertilizers are the major sources. In Northern Ireland, livestock manure is the primary source of NH3 emissions...
Article
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Background: A rapid and accurate test to detect SARS-CoV-2 is essential for controlling the transmission of the COVID-19. Rapid diagnostic tests are currently marketed, although it is uncertain how well they perform in actual clinical settings and with relevant subpopulations. We evaluated the clinical performance of the Direct Detect® SARS-CoV-2 D...
Conference Paper
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We are pleased that we met old colleagues and young scientists there interested in polar and alpine research and shared their geoscience and bioscience knowledge with us. Furthermore, we would like to thank the four keynote speakers for their interesting talks and the experience they passed on to us. This year, we heard 12 contributions in the form...
Article
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Several COVID-19 vaccines, some more efficacious than others, are now available and deployed, including multiple mRNA- and viral vector-based vaccines. With the focus on creating cost-effective solutions that can reach the low- and medium- income world, GreenLight Biosciences has developed an mRNA vaccine candidate, GLB-COV2-043, encoding for the f...
Preprint
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It is a global priority to better manage the biosphere, but action needs to be informed by monitoring shifts in the abundance and distribution of species across the domains of life. The acquisition of such information is currently constrained by the limited knowledge of biodiversity. Among the 20 million or more species of eukaryotes, just a tenth...
Article
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Background Bioscience subjects are essential as they allow nurses to have a clear understanding of the patient’s condition and ultimately allow them to provide appropriate and timeous care. However, these subjects remain a significant problem in the endeavour to produce highly competent nurses. Aim The study aimed to investigate the nursing studen...
Article
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To gain a deeper understanding of the genetic factors influencing the growth and development of Eriocheir sinensis, a well-known species of hairy crab found in Yangcheng Lake, this study focused on the de novo genome and full-length transcriptome information of the selected subjects. Specifically, Yangcheng Lake hairy crabs were chosen as the exper...
Article
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The Chinese soft-shelled turtle (Pelodiscus sinensis), an economically important aquatic species in China, displays considerable sexual dimorphism: the male P. sinensis is larger and, thus, more popular in the market. In this study, we obtained the full-length (FL) transcriptome data of P. sinensis by using Pacific Biosciences (PacBio)’s isoform se...
Article
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Background Healthcare personnel (HCP) are at risk for SARS-CoV-2 exposure in both the healthcare and community setting, and the rate of unconfirmed infection in HCP is unknown. Our objective was to measure the rate of SARS-CoV-2 seropositivity in HCP with no history of COVID-19, but who work with COVID-19 patients and/or specimens. Methods This wa...
Article
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Background Periprosthetic joint infection (PJI) is a devastating complication following joint replacement, associated with morbidity and mortality. Here, we established a clinically representative murine model of knee arthroplasty and determined the ideal bacterial inoculum that would result in PJI without causing significant limb compromise.Figure...
Article
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Background Cefiderocol (CFDC) is a siderophore cephalosporin with broad activity against Gram-negative bacteria including multi-drug resistant isolates. The in vitro activity of CFDC and comparator agents was evaluated against pediatric (0-17 years old) isolates collected in 2020–2022 as part of the SENTRY Antimicrobial Surveillance Program. In vit...
Article
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Background Biofilms formed by antibiotic-resistant bacteria in wound beds present unique challenges in terms of treating wound infections. In this work, the in vivo anti-biofilm activity of a novel electrochemical bandage (e-bandage) designed to continuously deliver low amounts of hypochlorous acid (HOCl) was evaluated against wound biofilm infecti...
Article
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Background Hand hygiene reliability is a top priority in healthcare. Infection Prevention and Control (IPC) programs often rely on clinical personnel to audit hand hygiene performance. Interrater reliability among auditors is critical to ensuring data validity. We evaluated whether spaced education, which increases long-term knowledge retention, co...
Article
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Background Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem is a thiopenem with activity against drug-resistant pathogens known to cause uncomplicated urinary tract infection (uUTI). Oral sulopenem is a bilayer tablet composed of sulopenem etzadroxil and probenecid, an organic anion transport inhibitor that delays renal ex...
Article
Full-text available
Background Taniborbactam is an investigational β-lactamase inhibitor that restores cefepime (FEP) activity against FEP-, carbapenem-, and multidrug-resistant Enterobacterales and Pseudomonas aeruginosa producing serine- and metallo-β-lactamases. Cefepime-taniborbactam (FTB) was superior to meropenem (MEM) for the primary composite endpoint of micro...
Article
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Background The BIDMC Optimization & Standardization for Treatment Outcomes in New England for Helicobacter Pylori (BOSTON-HP) study included 1002 patients with confirmed Helicobacter pylori (HP) via gastric histopathology from 2016-2022 to evaluate the effects of a Multidisciplinary Division Wide Program. Our previous data showed that demographic f...
Article
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Background Achromobacter and Burkholderia species are opportunistic pathogens in individuals with an immunodeficiency, most notably cystic fibrosis. Cefiderocol (CFDC) is a siderophore-conjugated cephalosporin with broad activity against Gram-negative bacteria. In this study, the activity of CFDC and comparator agents was determined against isolate...
Article
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Background Gram-negative bacterial bloodstream infections (GNB-BSI) are common and frequently lethal. Many patients experience recurrent GNB-BSI for unclear reasons. This study explores how antibiotic tolerance may lead to infection relapse.Figure 1:Flow diagram of relapsed versus recurrent infection. Approximately 63% of recurrent GNB-BSI are due...
Article
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Background Outpatient parenteral antimicrobial therapy (OPAT) allows patients to complete intravenous (IV) or high risk oral medications outside the acute inpatient setting. Data regarding OPAT in patients with immunocompromise (PWIC) are sparse. PWIC represent a vulnerable population due to underlying comorbidities. This study evaluated OPAT clini...
Article
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Background Investigation of the colonization dynamics of vancomycin resistant Enterococcus faecium (VRE) depends on reliable detection methods. In this study we investigated if metagenomic sequencing enhances our understanding of VRE gut colonization in addition to selective culture. Methods We performed metagenomic sequence analysis on 48 stool a...
Article
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Background A Phase 3 clinical trial evaluated ceftobiprole (BPR) for the treatment of Staphylococcus aureus bacteremia (SAB), including right-sided infective endocarditis (NCT03138733). We reported molecular characteristics of methicillin-resistant S. aureus (MRSA) along with the clinical outcomes. Methods 94 patients had MRSA isolated from baseli...
Article
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Background Healthcare-associated infections (HAIs) such as central line-associated bloodstream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), surgical site infections (SSI) and ventilator-associated events (VAE) are associated with increased patient morbidity, mortality, and healthcare related cost. One could expect a de...
Article
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Background rCDI is characterized by diarrhea reemergence after symptom resolution on standard-of-care antibiotics and positive test for C. difficile toxin production or toxin gene presence. In two phase 3 trials with varied diagnostic testing methods, dosing with fecal microbiota spores, live-brpk (FMS; formerly SER-109) was associated with low rCD...
Article
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Optical tweezers are an interesting tool to enable single particle analysis, especially when coupled with optical sensing and advanced computational methods. Nevertheless, such approaches are still hindered by system operation variability, and reduced amount of data, resulting in performance degradation when addressing new data sets. In this manusc...
Article
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Background Curvularia species are dematiaceous environmental molds that rarely cause disease in humans. Infections may be superficial or invasive and can present as disseminated infection or localized infection including keratitis, invasive fungal sinusitis (IFS), and skin and soft tissue infection (SSTI). Non-pathogenic colonization is also common...
Article
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Background Starting in 2020, antimicrobial stewardship efforts were coordinated to reduce outpatient consumption of FQs prescribed in 20 urgent care centers (UCCs) throughout a not-for-profit healthcare system. Coordinated efforts included clinician education on FQ treatment alternatives and direct prescriber audit and feedback in specific cases. A...
Article
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Background Definition of the microbiology of pleural space infection has been challenging due to the poor yield of conventional culture, a challenge that has led to recommendations for broad spectrum antimicrobial therapy for these infections. Since August 2019, we have offered a 16S ribosomal RNA gene PCR assay followed by Sanger or next generatio...
Article
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Background Ceftobiprole medocaril is an intravenously (IV) administered cephalosporin that is rapidly converted in vivo to the active moiety ceftobiprole. Ceftobiprole medocaril is being developed for the treatment of patients with ABSSSI and CABP. PK-PD target attainment analyses were performed to support the dosing regimens selected for these ind...
Article
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Background Empiric antibiotic use in patients hospitalized with COVID-19 was common early in the pandemic despite low rates of bacterial co-infection. Little is known, however, about trends in antibiotic prescribing for patients with COVID-19 with and without viral sepsis. Methods We retrospectively identified all adults admitted to 5 Massachusett...
Article
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Background Progression from mild to severe SARS-CoV-2 infection correlates with humoral and cellular immune signatures that adjust to a multiplying viral load. Enhancing immunity with host-directed therapy, such as sargramostim (yeast-derived, recombinant human granulocyte-macrophage colony-stimulating factor [GM-CSF]), may prevent disease progress...
Article
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Background Live biotherapeutic products (LBPs) are adjunctive therapies to prevent recurrence of Clostridioides difficile infection (CDI). In this post hoc subgroup analysis, the durability of fecal microbiota, live-jslm (REBYOTA™; abbreviated here as RBL, previously known as RBX2660), the first microbiota-based LBP approved by the US Food and Drug...
Article
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Background Beta-lactam/beta-lactamase inhibitor (BL/BLI) combinations and cefiderocol (FDC) have been recommended for the treatment of carbapenem-resistant Enterobacterales (CRE), but extensive comparisons of these agents are limited. We tested the activity of aztreonam-avibactam (ATM-AVI), ceftazidime-avibactam (CAZ-AVI), meropenem-vaborbactam (ME...
Article
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Background Several randomized controlled trials (RCT) have shown that short-course (∼7 days) antibiotic treatment is non-inferior to longer antibiotic courses (∼14 days) in patients with uncomplicated bloodstream infection (BSI) with mostly susceptible Gram-negative bacteria. Here, we evaluate short-course therapy in ceftriaxone-resistant E. coli B...
Article
Full-text available
Background Cefepime-taniborbactam (FTB) is an investigational β-lactam/β-lactamase inhibitor combination that is active against carbapenem-resistant Enterobacterales and multidrug resistant Pseudomonas aeruginosa expressing serine and metallo-β-lactamases. CERTAIN-1 (Cefepime Rescue with Taniborbactam in cUTI) demonstrated that FTB was superior to...
Article
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Background Fecal microbiota transplantation (FMT) can effectively decolonize multidrug-resistant organisms but its efficacy is variable. We evaluated the impact of FMT treatment at eliminating carbapenemase-producing Enterobacterales (CPE) carriage compared to spontaneous decolonization and identified microbial signatures of successful decolonizati...
Article
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Background The 2023 Duke-ISCVID criteria for IE were recently introduced to improve classification of IE for research and clinical purposes (Table 1). We compared the diagnostic accuracy of the new criteria with the 2000 modified Duke criteria, the 2015 European Society of Cardiology (ESC) criteria and a clinically adjudicated reference standard by...
Article
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Background The RAPIDS GN trial, a prospective randomized controlled trial, showed that rapid blood culture antibiotic susceptibility testing (AST) led to faster antibiotic therapy changes compared to standard of care (SOC) testing for Gram negative bacteremia (Banerjee et al, Clin Infect Dis (2021) 73:e39-e46). A secondary analysis of the data was...
Article
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Background SARS-CoV-2 viral dynamics offer insights into clinical trajectories and immune responses. While research has explored SARS-CoV-2 viral kinetics by variant and immune status, changes in population immunity make results difficult to interpret. Here, we examined SARS-CoV-2 viral kinetics in a community-based cohort of immunologically naïve...
Article
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Background Clostridioides difficile infection (CDI) is a complex disease involving host and microbial factors. The influence of patient clinical state complicates identification of pathogen genetic variation associated with disease progression. Stratification of patients by underlying comorbidity may improve prediction of important C. difficile gen...
Article
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Background Ceftobiprole medocaril is an intravenously administered cephalosporin prodrug that is rapidly converted in vivo to ceftobiprole which has activity against Gram-positive and -negative organisms. A population pharmacokinetic (PK) model was constructed from nine Phase 1 studies and three Phase 3 studies in patients with acute bacterial skin...
Article
Full-text available
Background Treatment options for mucocutaneous herpes simplex virus infections (HSV) refractory or resistant (r/r) to acyclovir (ACV) are limited. High-dose ACV continuous infusion, foscarnet (FCN), cidofovir (CDV), and/or topical agents have been used. We report treatment patterns and outcomes of r/r HSV after allogeneic hematopoietic cell transpl...
Article
Full-text available
Background Cefiderocol (CFDC) is a siderophore-conjugated cephalosporin with broad activity against Gram-negative bacteria including multi-drug resistant organisms. The in vitro activity of CFDC and comparator agents was evaluated against Enterobacterales isolates collected during 2020-2022 in the SENTRY Antimicrobial Surveillance Program, stratifi...
Article
Full-text available
Background A rare strain of extensively drug-resistant Pseudomonas aeruginosa was identified from contaminated artificial tear products that caused outbreak across 16 US states in March 2023. The strain carries Verona integron-encoded metallo-β-lactamase (VIM) and Guiana-Extended Spectrum-β-Lactamase (GES), a combination not previously identified i...
Article
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Background Cephalexin (LEX), cefuroxime axetil (CXM), and cefpodoxime (CPD) are common oral cephalosporins used to treat gram-positive and gram-negative infections. However, there is a paucity of PK/PD analyses to inform optimal dosing regimens, which drug may be preferred for a particular organism, and the susceptibility testing interpretive crite...
Article
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Background Obtaining follow-up blood cultures (FUBCs) to document clearance of gram-negative bloodstream infections (GN-BSI) is controversial. In a historical cohort (2002-2015), we previously showed that obtaining FUBC was associated with decreased mortality. However, it is unclear if this result is applicable to present-day patients given changes...
Article
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Background Cefiderocol (CFDC) has broad in vitro activity against non–fermenting Gram-negative bacteria which often present treatment challenges due to multi-drug resistance. Stratified by infection type, the activity of CFDC and comparator agents was evaluated against Pseudomonas aeruginosa (PSA), Acinetobacter baumannii-calcoaceticus complex (ABC...
Article
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Background The optimal duration of remdesivir for hospitalized patients with COVID-19 remains unclear. National Institute of Health (NIH) Guidelines recommend a standard duration of 5 days or until hospital discharge. This study aims to compare the outcomes of hospitalized patients who received ≤ 4 days of remdesivir compared to those who received...
Article
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Background As disease patterns shift with changing demographics and climate, developing comprehensive and scalable tools for tracking and identifying emerging pathogens is an increasingly critical component in mounting a robust public health response. Metagenomic next-generation sequencing (mNGS) provides unbiased detection of etiological agents fr...
Article
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Background Staphylococcus aureus is the leading cause of death due to bacterial blood stream infection. Female sex was a risk factor for mortality in S. aureus bacteremia (SAB) in some studies, but not in others. The aim of this systematic review and meta-analysis was to determine whether female sex is associated with mortality in SAB. Methods The...
Article
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Background Solid organ transplantation (SOT) is lifesaving, but donor-derived infections can be associated with significant morbidity and mortality. Candida species are common colonizers in deceased donors managed in the intensive care environment, and transmission to the recipient through transplantation is a described phenomenon. We sought to cha...
Article
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Background Clostridioides difficile (C. difficile) infection (CDI) is a leading cause of nosocomial infection that can range from mild diarrhea to life threatening pseudomembranous colitis and death. Aging as well as defects in the host immune response including failure to develop antibody response against C. difficile antigens increases the risk o...
Article
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Background The COVID-19 pandemic highlighted the potential pathogenicity of betacoronaviruses. This elucidates the need to further investigate human coronaviruses (HCoV), which includes both alpha and betacoronaviruses, to better understand their seasonality and severity among children. Methods The New Vaccine Surveillance Network (NVSN) enrolled...
Article
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Background Ceftobiprole medocaril is an intravenously (IV) administered cephalosporin prodrug that is rapidly converted in vivo to ceftobiprole, which has activity against Gram-positive and Gram-negative organisms. Ceftobiprole is being developed for the treatment of patients with S. aureus bacteremia (SAB). Pharmacokinetic-pharmacodynamic (PK-PD)...
Article
Full-text available
Background Integrase strand-transfer inhibitors (INSTIs) are associated with body weight gain among women living with HIV (WLH) in the Women’s Interagency HIV Study (WIHS). The role of antiretroviral therapy (ART) pharmacokinetics in INSTI-associated weight gain is unknown. We report the relationship between INSTI plasma concentrations and weight c...
Article
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Background Venetoclax is a small molecule inhibitor of BCL-2 used in the treatment of acute myelogenous leukemia and chronic lymphocytic leukemia. Recent post-marketing studies on venetoclax suggested that it may predispose to opportunistic infections (OIs). We sought to systematically review the randomized controlled trial (RCT) evidence on veneto...
Article
Full-text available
Background Sulopenem etzadroxil, the oral (PO) prodrug of the active moiety sulopenem, is a thiopenem in development for the treatment of uncomplicated urinary tract infection (uUTI). Oral sulopenem is a bilayer tablet composed of sulopenem etzadroxil and probenecid, an organic anion transport inhibitor that delays renal excretion of sulopenem. The...
Article
Full-text available
Background Microbial cell-free DNA (mcfDNA) sequencing can establish the etiology of multiple infectious syndromes by identifying pathogen DNA from the plasma of infected patients. Here, we describe the potential impact of a positive mcfDNA result on clinical decision making among immunocompromised adults with suspected pneumonia. Methods This pro...
Article
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Background Clustering methods using machine learning may be useful for identifying variables predicting clinical outcomes. Despite the need to better understand risk behaviors of Bacterial Vaginosis (BV), the most common cause of abnormal vaginal discharge linked to STI and HIV acquisition, machine learning methods have not been used to better unde...
Article
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Background Methicillin-resistant Staphylococcus aureus (MRSA) biofilms can be resilient to the human immune system and antibiotics, a challenge augmented by acquired antimicrobial resistance. Phage therapy is being evaluated for biofilm-associated infections. Methods Here, model phages SaMD07ø1 and SaRB105030ø5 were evaluated against their hosts S...
Article
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Background Sulbactam-durlobactam (SUL-DUR) is a β-lactam/β-lactamase inhibitor combination in development for the treatment of infections caused by Acinetobacter baumannii-calcoaceticus complex (ABC), including multidrug-resistant and carbapenem-resistant isolates. SUL-DUR is predominantly renally eliminated, with altered exposures in patients with...
Article
Full-text available
Background Ceftobiprole medocaril is an intravenously (IV) administered cephalosporin that is rapidly converted to the active moiety ceftobiprole in vivo. Ceftobiprole medocaril is currently being developed for the treatment of patients with SAB, including infective endocarditis. PK-PD target attainment analyses were performed in order to provide s...
Article
Full-text available
Background Hospital-onset (HO) carbapenem-resistant Enterobacterales (CRE) infections are increasing; recently, the Centers for Disease Control and Prevention (CDC) reported a 35% increase during the COVID-19 pandemic. We evaluated the impact of HO CRE blood stream infections (BSI) on outcomes compared to community-onset (CO) CRE BSI. Methods Pati...
Article
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Background Broad-range bacterial PCR sequencing (BRBPS) has emerged as a novel tool to detect fastidious organisms. While its utility has been characterized in different specimen types, its role in culture-negative blood specimens remains poorly understood. Methods We reviewed all clinical specimens sent for culture-negative blood BRBPS (blood, se...
Article
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Background C. difficile infection is more common and severe in people over 65-years old. Understanding the pathogenesis within the triangle of host, pathogen, and the microbiota in aged population will help decrease the disease severity. Methods Young (3-month-old) and aged (22 to 25-month-old) male and female C57BL/6 mice were treated with 0.5g/L...
Article
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Background Fecal transplant and other donor-derived treatments promote a gut environment resistant to CDI, but these treatments have inherently variable quality attributes, are difficult to scale, and can transfer harmful pathogens. VE303 is a rationally defined consortium of 8 purified, clonal strains, overcoming the limitations of donor-derived t...
Article
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Background Staphylococcus aureus (SA) infections, both methicillin-susceptible and methicillin-resistant (MSSA, MRSA), cause significant morbidity among infants in neonatal intensive care units (NICU). Colonization usually precedes infection. We studied the molecular epidemiology of SA colonization in NICU infants using whole genome sequencing (WGS...
Article
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Background Characteristics of the gut microbiome may be useful to predict resistance to colonization and expansion of pathogenic organisms such as C. difficile. In this study, we evaluated whether inclusion of microbiome characteristics improved a clinical prediction model for in-hospital mortality. Methods Rectal or fecal swab samples were collec...
Article
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Chirality is a common occurrence in nature and forms a critical basis for life. The unique optical activity of chiral nanomaterials plays an important role in the nanobiology field, particularly in the regulation of reactive oxygen species (ROS), both in cells and in vivo. By regulating ROS, chiral nanomaterials can achieve numerous biological effe...
Article
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Background Difficult to Treat Resistant (DTR) Gram-negative isolates show treatment-limiting resistance to all first-line agents; β-lactams and fluoroquinolones. Cefiderocol (CFDC) is a siderophore-conjugated cephalosporin with a unique mode of entry into bacteria, showing good activity against Gram-negative bacteria. Here, susceptibility of CFDC a...
Article
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Background Healthcare associated infections (HAIs) and outbreaks due to hospital sinks have been noted for many years, however, there remains no standardized environmental hygiene protocol to combat these HAIs. The goal of this study was to evaluate the impact of a sink environmental hygiene intervention on gram negative microbial load. Methods We...
Article
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Background Periprosthetic joint infection (PJI) is associated with significant morbidity. Management includes surgery and prolonged antibiotic treatment. Few studies have evaluated rates of acquired antimicrobial resistance in bacteria causing PJI. The aim of this study was to describe antimicrobial resistance profiles of bacteria causing PJI and t...
Article
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Background Infants ≤ 90 days old are at increased risk of severe disease from both viral and bacterial pathogens. Differentiating between these two etiologies has long presented a diagnostic challenge and has resulted in many risk algorithms to determine which infants are infected by bacteria and require antibiotics. The increased availability of r...
Article
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Background A third dose of measles-mumps-rubella vaccine (MMR) may be administered for various reasons, but there are limited data on long-term immunogenicity. We assessed persistence of measles and rubella neutralizing antibodies among adults after receipt of three MMR doses. Methods Adults who received two MMR doses in childhood and a third dose...
Article
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Background Clinical outcomes associated with bacterial bloodstream infections (BSI) are influenced by multiple factors, including the infecting bacterial species and choice of antibiotic therapy. However, the mechanisms by which differences in such factors influence patient outcomes are poorly understood. We hypothesized that variations in bacteria...
Article
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Background The impact of host genetic variability on the outcome of S. aureus infection is unknown. HLA variation has evolved to ensure broad presentation of pathogen derived peptides to initiate protective adaptive immune responses. In genome-wide association studies we identified specific HLA class II variants (HLA-DRB1*04:01 & 04:02) that are po...
Article
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Background Reporting extended-spectrum beta lactamase (ESBL) status on microbiology results for Enterobacterales is not required by laboratory, infection prevention, or antimicrobial stewardship guidelines. Ceftriaxone (CRO) resistance may be utilized as a proxy for ESBL production. Current practice guidelines recognize select non-carbapenems as ac...
Article
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Background Low-level viremia (LLV) is common in people with HIV taking antiretroviral therapy (ART), and has been associated with virologic failure, resistance, and may increase the risk of non-AIDS comorbidities (NACM). However, despite sex-differential HIV pathogenesis, treatment response, and NACM risk, women have been underrepresented in prior...
Preprint
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Long-read amplicon profiling through read classification limits phylogenetic analysis of amplicons while community analysis of multicopy genes, relying on unique molecular identifier (UMI) corrections, often demands deep sequencing. To address this, we present a long amplicon consensus analysis (LACA) workflow employing multiple de novo clustering...
Article
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Binashikhbubkr K, Setyawan AD, Naim DM. 2023. Morphometric variations of Kawakawa (Euthynnus affinis Cantor, 1849) in Malaysian and Yemeni waters. Nusantara Bioscience 15: 269-278. Euthynnus affinis Cantor, 1849 (Kawakawa), a small epipelagic tuna that migrates, is one of the most commercially significant tunas in Indo-Pacific subtropical and tropi...
Preprint
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The recent evolution of nucleic acid sequencing has brought about a significant transformation in our ability to unravel the intricacies of genetic information. Massively parallel sequencing technologies have generated immense volumes of short-read sequence data, contributing significantly to genomics, transcriptomics, and epigenomics. However, the...
Article
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Background Nursing students often find bioscience courses, such as pathophysiology, challenging. Utilizing Twitter to provide concise course content and answer students’ questions before exams may be beneficial. The objective of this study was to determine if using Twitter can improve nursing students’ academic performance and satisfaction with pat...