Science topic

Biopolymers - Science topic

Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.
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Bacterial biopolymers are a hot topic for innovation, and many patents have been filed covering their production, application, and extraction methods. Does anyone published patents on bacterial biopolymers? Please, discuss it! We want to learn!
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Yes, numerous patents have been filed on bacterial biopolymers, particularly in areas like production, extraction, and application. Key biopolymers include PHA (Polyhydroxyalkanoates), exopolysaccharides (EPS), and bacterial cellulose, which are studied for use in packaging, medical, and environmental applications. Patents often focus on genetic engineering of bacteria for higher yields, efficient extraction methods, and innovative applications such as biodegradable plastics or drug delivery systems. Companies like BASF, NatureWorks, and LG Chem are active in patenting biopolymer production technologies. The main challenge lies in reducing production costs, but opportunities are significant, particularly for sustainable materials to replace petroleum-based plastics.
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I have synthesized a film containing biopolymer(Soluble in DMSO) and TiO2 nanoparticles what solvent would be perfect to dissolve it ?
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It depends upon the polymer you used. Later on separate the film polymer from the NP.
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I saw a lot of research showing the application of DNA as starting material for synthesis of patterned DNA hydrogels or nucleospheres that utilize the self-complementarity of custom designed synthetic oligonucleotides to form such nano and microstructures (1). Another technology exists which uses DNA along with metal ions to form particles through coordination driven self assembly (2). Researchers have also shown the application of such DNA origami structures constructed from custom oligonucleotides and phage DNA in orthotopic tumor-bearing mice models for efficient drug delivery (3).
I am curious to know if we can isolate DNA from other cells (Plants/bacteria/mammalian) and use it to generate such DNA micro or nanoparticles that could have drug delivery applications. What would be the limiting factors in this ?
2. Engineering multifunctional DNA hybrid nanospheres through coordination-driven self-assembly. https://doi.org/10.1002/anie.201810735
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You can isolate DNA from other cells (plants/bacteria/mammals) and use it to create micro- or nanoparticles of DNA that could be used in drug delivery. Limitations:
1. lack of usefulness of such a drug delivery strategy
2. impact of bacterial DNA on human health
3. correct formation of a container of DNA to contain the drug
4. toxicity of oligonucleotides to the human body.
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if we use an organic solvent how we will distinguish that the toxicity is due to the plastic not due to the solvent used. Please guide
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Dear Itrat Zahra, since toxicity is the subject of the study then water is the best choice and avoid halogenated solvents. My Regards
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Actually i want to know if i have grafted one biopolymer to another derivatized biopolymer and then reinforced metal nanoparticles into it , then what factors should be remind to draw a chemical reaction for this ?
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Dear Sakshi Saini, in your case structure prediction is meaningless, since both the main chain polymer and the grafts will retain their basic structure, and the only change will occur at the attachment points. NMR and other spectroscopic techniques will give the percentage and the distribution of grafts and the newly formed bonds/group. Mass spectroscopy also justify the success of grafting. For the NPs it depends on the mode of modification, is it simple adsorption or direct chamical attachment. More details are necessary to give further suggestions. My Regards
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Dear scientific writer ,,i want a suggestion i have submitted a review on synthesis and derivatization of biopolymer ,,editor ask me to add characterization in it from previous study ,,so guide me how i cam make my articles effective with this ?
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Dear all, the previous study is it yours or it is of someone else? If it is published, you have just to add it with the reference article. If it is an unpublished data of you or another researcher, just put in the reference section the mention ' unpublished data with permission '. My Regards
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I am thrilled to share our latest project with Frontiers which is up and running. Together with Dr. Bárbara Tomadoni, Dr. Antonio Guerrero and Dr. Norma Marcovich, we are leading a Research Topic on "Sustainable Active Packaging for Food Safety and Preservation: Technological, Consumer, and Environmental Perspectives". You can read more here 👉 https://www.frontiersin.org/research-topics/65159/sustainable-active-packaging-for-food-safety-and-preservation-technological-consumer-and-environmental-perspectives We look forward to your contribution if you are working on sustainable active packaging! 🤝 📆 Summary submission deadline: 22 September 2024 📆 Manuscript submission deadline: 10 December 2024 hashtag#biodegradable hashtag#packaging hashtag#foodquality hashtag#foodsafety hashtag#biopolymers hashtag#sustainability
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Is this a discussion or just an advertisement?
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I am currently processing a peritoneal dialysis solution with 7.5% icodextrin and would like to verify whether its concentration remains the same post-processing or decreases, whether slightly or significantly. How can I quantify icodextrin in an aqueous solution?
As icodextrin is a polysaccharide/glucose biopolymer, could I use HPLC-RID for this purpose? The intended mobile phase is 80% acetonitrile water, and the column proposed is Lichrospher® 100 NH2 Purospher® STAR NH2 5um, suitable for carbohydrates (mono-, di-, and oligosaccharides).
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I prefer the Ca-type ligand exchange (ion exclusion) polymeric column instead of NH2-type ligands column to get high dp oligosaccharides as a single response rather than polydispersed peaks...
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I want to know the method of sample preparation in ppm.
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Novel and unique properties of materials are considered to determine suitable sensing materials. Because of interesting naturally-based characteristics, biopolymers including cellulose, nanocrystalline cellulose and chitosan have been actively investigated in the last decades. Colorimetric, electrochemiluminescence, fluorescence and surface Plasmon resonance are the list of optical sensors. Ammonia gas sensors can be analyzed using techniques like electronics, electrochemistry, tunable diode laser spectroscopy, surface acoustic wave, and field effect transistors. Optical ammonia sensing of a biopolymer can be performed using surface Plasmon resonance (SPR) with a response time of 2-3 seconds and a detection limit of 1 ppm at room temperature. Furthermore, Optical sensing films using organically modified silicates (ORMOSILSs) can detect ammonia with a detection limit of 0.01± g/ml and a response time of 2 minutes. Cellulose acetate membranes with cellulose acetate-proline ionic liquid display the best ammonia sensing with a detection value of 1 ppm and response and recovery times of 60 and 78 seconds respectively.
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I'm interested in submitting a research proposal to the call 2025 "Egypt-France Imhotep Mobility Project." Therefore, I'm looking for a French collaborator who specializes in material science, environmental science, nanoparticles, or biopolymers. I would appreciate it if anyone could help me with this.
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I can't help as partner, but I can help to prepare a project that will help you find a partner. Using an equation of state for materials under stress, you can study the relationship between the specific surface area of nanomaterials, their concentration and the properties of composites. I would guide you to "enter" this subject and you would then present it to organizations like the CNRS in France.
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I need more articles on kaolinite clay and the same clay treated by number of geotechnical methods
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DILL, H.G. (2016) Kaolin: soil, rock and ore  From the mineral to the magmatic, sedimentary, and metamorphic environments.- Earth Sciences Reviews 161: 16-129.
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I want to prepare a starch encapsulated nano clay biopolymer composite where i can add micronutrients such as Molybdenum, Zinc and primary nutrient potassium. Moreover, I also want to add microorganism Arthrobotrytis oligospora to it. Please suggest me the standard procedure for doing such activities?
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Thank you for your recommendation Aina
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What concentration(w/v) should prepare for take this spectra?
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Dear all, first be sure that the substance has an absorption within UV-Vis domain. If the maximum absorption is known from literature for example, then the corresponding concentration is deducible from Beer-Lambert law. My Regards
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What works describe these methods? Thank you!
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Here are five commonly used approaches:
1. Reinforcement Techniques: For example, the addition of carbon fibers or ceramic nanoparticles can improve the strength, stiffness, and fracture toughness of the composite.
2. Surface Modification: Techniques like plasma treatment, chemical functionalization, or coating deposition can alter the surface properties, promoting cell adhesion, reduce inflammation, or preventing bacterial colonization.
3. Polymer Matrix Modification: These modifications can enhance mechanical strength, thermal stability, or degradation resistance.
4. Fabrication Techniques: Techniques like compression molding, 3D printing, electrospinning, or fiber placement can control the orientation, alignment, and distribution of the reinforcing agents, resulting in tailored mechanical properties and structural characteristics.
5. Hybridization: Combining different types of materials in the composite can result in synergistic effects and improved performance. For example, incorporating organic and inorganic components, such as polymers and ceramics, can combine mechanical strength, flexibility, and bioactivity.
Good luck: partial credit AI
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  1. physical appearance
  2. method of preparation
  3. properties
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  1. Yes, all mentioned properties physical appearance; method of preparation
  2. the film may be made of linear polymer, but also there are a lot of examples when covalently linked .
  3. Hydrogels manly 3D covalently cross-linked polymeric structures swallen on water. although there are a lot of physically cross-linked hydrogels made of natural poloysacharides(alginate, chitosan) or synthetic PVA
  4. films are mainly dry polymer
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Cellulose is a highly desirable biopolymer which has many applications in modern technologies. But, cellulose has lignin and hemicellulose which is undesirable for applications like energy harvesting. So, how do we remove these materials from cellulose?
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Kraft pulping will degrade hemicellulose. There has been quite a bit of research in methods of preserving this valuable carbohydrate. This has been accomplished through water or acid prehydrolysis. Not sure I understand your statement regarding energy - lignin is what is currently burned in Kraft recovery boilers to produce steam.
Extraction of Hemicellulose from Loblolly Pine Woodchips and Subsequent Kraft Pulping | Request PDF (researchgate.net)
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Anyone Can suggest me Lignin Bio-polymer application and its uses or any research which is currently happening in Lignin Nano-particles or lignin nano-composites materials in human welfare and in drug delivery.
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Thank you for sharing this research.
You can have a look on lignin-based and covalent adaptable networks here.
Kind regards,
Davide
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TiO2 contents are dependent on room temperature optical transmittance (in the UV-Vis region) of different PLA nanocomposites with the neat PLA film. Optical transmittance of polymer-based biodegradable films is significant for sundry industrial applications, especially in food packaging where the attractiveness of the food by customers potentially depends on the aesthetic view by naked eyes under visible light illumination.
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Dear Doctor
Go To
Biopolymers – Application in Nanoscience and Nanotechnology
  • March 2016
  • DOI: 10.5772/62225
  • In book: Recent Advances in Biopolymers
  • Sneha Mohan Bhagyaraj
  • Oluwatobi S. Oluwafemi
  • Nandakumar Kalarikkal
  • Sabu Thomas
  • Sandile Songca
"Abstract
Polylactic acid or polylactide (PLA, Poly) is a biodegradable thermoplastic aliphatic polyester derived from renewable resources, such as corn starch, tapioca roots, chips, starch, or sugarcane. PLA is obtainable primarily by the ionic polymerization of lactide, a ring closure of two lactic acid molecules. At temperatures between 140 and 180 °C and under the action of catalytic tin compounds (such as tin oxide), a ring-opening polymerization takes place. Lactide itself can be made through lactic acid fermentation from renewable resources such as starch by means of various bacteria. PLA can also be produced directly from lactic acid by polycondensation. However, this process yields low molecular weight polymers, and the disposal of the solvent is a problem in the industrial production. The properties of PLA primarily depend on the molecular mass, the degree of crystallinity, and possibly the proportion of co-monomers. A higher molecular mass raises Tg, as well as Tm, tensile strength, elastic modulus, and lowers the strain after fracture. Due to the CH3 side group, the material has water-repellent or hydrophobic behavior. PLA is soluble in many organic solvents, such as dichloromethane or the like. PLA has higher transparency than other biodegradable polymers, and is superior in weather resistance and workability."
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What polymers containing phosphorus are used in maxillofacial surgery? List all such polymers. Thank you!
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In maxillofacial surgery, polymers containing phosphorus are occasionally used for various purposes, particularly in reconstructive procedures and as biomaterials. Two common examples of polymers with phosphorus used in maxillofacial surgery are:
  1. Poly-L-Lactic Acid (PLLA): Poly-L-Lactic Acid is a biodegradable synthetic polymer that contains phosphorus. It is used in maxillofacial surgery for its biocompatibility and ability to stimulate tissue regeneration. PLLA is commonly employed in facial contouring procedures to add volume to areas affected by bone loss, such as the cheeks and jawline. It is often delivered in the form of injectable fillers and gradually stimulates collagen production, providing long-lasting results.
  2. Polyglycolic Acid (PGA): While PGA itself does not contain phosphorus, it is often combined with a polymer containing phosphorus called Polyphosphazene to create a composite material known as Polyphosphazene/PGA. This combination enhances the mechanical properties and biocompatibility of the material. Polyphosphazene/PGA composites have been used in maxillofacial surgery for bone tissue engineering applications. They act as scaffolds that support bone regeneration, especially in cases of bone defects or fractures.
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What 3D polymers with carbon, oxygen and phosphorus, but without hydrogen, are used in maxillofacial surgery?
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What you are probably looking for is a polyester substrate such as PCL, PLA, PLGA, etc. that is loaded with hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂) or calcium phosphate or other phosphorous-based osteogenic materials.
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Special Issue Information
Dear Colleagues,
The growing need for food production through sustainable cultivation practices, without reducing crop yield and producer income, is a major objective due to increased environmental pollution and the gradual degradation of cultivated soils. Various compounds with bioactive properties can be utilized as biostimulants to boost plant growth and development under normal and stressful conditions. So far, six distinct categories of biostimulants have been recognized, including microbial inoculants; humic substances, such as humic and fulvic acids; protein hydrolysates and amino acids; biopolymers; inorganic compounds; and seaweed extracts, all of which are commercially available with wide applications in agriculture. The most important biostimulant effects on crops are the acceleration of crop establishment, the improvement in nutrient uptake and nutrients use efficiency, the induction of tolerance to biotic and abiotic stressors, the improvement in seed germination, the increase in shelf life of perishable products, the reduction in nutrients leaching, the improvement in root development, the removal of heavy metals from contaminated soils, the improvement in crop performance, the stimulation of the immune system of plants, the improvement in visual quality of final products, and the induction of the biosynthesis of plant defensive biomolecules. Different classification approaches have been suggested so far, based either on the origin of each biostimulant, such as biological or non-biological, microbial and non-microbial, or on the mode of action which divides biostimulants into phytohormonal and non-phytohormonal ones.
This Special Issue focuses on the roles and functions of different types of biostimulants on different agricultural and horticultural crops within the framework of sustainable crop management, aiming to gather critical and important information regarding their positive effects on plant growth and final yield, as well as their impacts on the quality of the final product. Furthermore, the major limitations of these practices as well as the future prospects of biostimulant studies will be presented.
Keywords= biostimulants; chitosan; arbuscular mycorrhizal fungi; amino acids; organic farming; vegetable crops; horticultural crops; microbial biostimulants
**Dr. Mohamad Hesam Shahrajabian
(Guest Editor
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China Interests: organic agriculture; crops; biostimulants; horticulture; forage crops; soil science; sustainable agriculture)
**Prof. Dr. Spyridon A. Petropoulos
(Guest Editor
Department of Agriculture, Crop Production and Rural Environment, University of Thessaly, 38446 Volos, Greece Interests: organic agriculture; agrobiodiversity; vegetable crops; biostimulants; horticulture; fruit quality; wild edible species; essential oils; medicinal and aromatic plants; stress physiology; bioactve compounds Special Issues, Collections and Topics in MDPI journals)
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Dear, Dr. M. Hesam Shahrajabian
I am very grateful for the efforts of you researchers in the production of natural products.
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Hi all,
I have been reading about quantification methods of sericin and fibroin. There are methods reported like FTIR, BCA, amino acid hydrolysis etc. I don't understand how it relates to exact sericin/fibroin titers in an isolate.
Does any body know of using or read about methods that are more accurate like ELISA or western for quantification of sericin or fibroin in protein isolate?
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While I appreciate your efforts to assist me, I would like to kindly request that you refrain from adding answers that come from AI-based model.
As you may know, I am here to gain a practical scientific approach to deal with these problems from people who are skilled and experienced in that area.
Bandla Ramesh Therefore, I am seeking the knowledge and insights that come from real-life experiences and expertise, rather than solely relying on machine-generated responses.
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This the XRD Spectrum of the polymer being carbonized.
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Hello,
The X-ray diffraction pattern of a material can reveal information about the crystalline/amorphous structure and phase composition of the materials. In the case of biopolymers, they typically show broad peaks due to the overlapping of different crystal planes within the polymer chains and also because of their semi-crystalline nature whereas, the carbonates, typically show well-defined and sharp diffraction peaks due to their highly ordered structure.
Thus, depending on the relative quantities of the two components and the level of crystallinity in each component, the diffraction spectra in a biopolymer-carbonate composite may exhibit both broad and sharp peaks. The peaks may also show shifting or broadening due to the interaction between both components in the composite. Based on this spectral analysis, one can determine the information regarding the phase composition and crystalline structure of the material.
Hope this information might help you in your XRD analysis.
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I prepare a chitosan solution in acetic acid (0.5 M). Some of the small threads are remained in the solution. In literature it is reported that solution is filtered before using. I want to know which filter is suitable for the filtration of chitosan solution?
Thanks
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For filtering chitosan solutions, it is recommended to use a filter with a pore size of 0.2 µm or smaller
One suitable filter for this purpose is a syringe filter with a 0.2 µm pore size, made of materials such as nylon, PVDF, or PTFE. These filters can effectively remove particles and aggregates from chitosan solutions without causing clogging or loss of chitosan
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Cigarette butts are one of the most poisoning (watersoluble nicotin an many others) waste problems for water and soil on earth. This is the toxic aspect of butts. The sencond heavy aspect is the possible degradation to microplastic of the biopolymer Cellulse acetate of the filter. Does anybody know or find scientific work regarding this microplastic state of CA during biodegradation?
Your detailed answer would be appretiated most.
Peter
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@ Abdulrasheed Abdulqadri.
New chat
Cigarette butts are one of the most poisoning (watersoluble nicotin an many others) waste problems for water and soil on earth. This is the toxic aspect of butts. The sencond heavy aspect is the possible degradation to microplastic of the biopolymer Cellulse acetate of the filter. Does anybody know or find scientific work regarding this microplastic state of CA during biodegradation?
Cigarette filters, made from cellulose acetate, can take several years to fully degrade in the environment. During this time, they may break down into smaller pieces and potentially contribute to microplastic pollution.
Studies have found that cigarette filters can release microplastic fibers when they are smoked or when they come into contact with water. Some research has also suggested that these fibers may be ingested by marine animals and other wildlife, raising concerns about their potential impact on the environment and on animal health.
However, it is worth noting that the extent to which cigarette filters contribute to microplastic pollution is still not fully understood, and more research is needed to better understand the potential impacts of these materials on the environment and on human health.
In the meantime, it is important to properly dispose of cigarette butts and to reduce our overall use of tobacco products, in order to minimize the potential negative impacts on the environment and public health.
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A while ago I did research on arabinoxylan gels using maize arabinoxylans sourced from Cambridge Biopolymers Ltd (UK). I would like to pursue this work further (and include mixed linkage glucans), but I find that the company has closed. Can anyone tell me if there are other companies which sell similar materials (preferably in the UK)?
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The problem with Megazyme is that they only sell in 3g or 5g quantities. I need 100 - 500g. Cambridge Biopolymers used to offer that, but so far I haven't been able to find anyone else who does.
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Dear scientists
Which type of dialysis membranes are preferable to use with chitosan and biopolymers ?
Can be used one more time these membranes?
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Dear Hazem Choukaife
Thank you for your response. In addition, is it suitable to use centrifuger (if yes which type)?
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Electrospinning
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Dear Akuleti Saikumar, you can change the ionic strength by adding small amount of salt, or use a higher conductivity constant solvent. What is the solvent used ? My Regards
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Bacterial cellulose (BC) is a natural biopolymer metabolized by Gram-negative bacteria strains in Carbon- and Nitrogen-rich media. Due to its natural purity and biodegradability it is considered to be an exceptional biomaterial with versatile scientific and commercial applications. Due to such a prominent potential use, further studies on such kind of materials should be established. Thus, what are the potential methods to study mechanical, molecular and structural properties of bacterial cellulose-based composites?
Thanks for any kind of your ideas and thoughts.
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Dear Vadym Chibrikov, there are various applications of BC in composites. Please have a look at the following documents. My Regards
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I am trying to prepare drug-loaded porous silica nanoparticles coated with biopolymers. I want to tag some targeting ligands and some molecules. I wanted to know if the functionalization should be done on the surface of the coated biopolymer or the silica nanoparticles?
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in downstream processing of biopolymer some quantity of protein still remains even after treating enzymatically which are known for protein removal.
looking for complete removal of protein from polymer, please suggest commercially feasible options.
protein source is bacteria whose outer layer consist of lipids and protein
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Dear all, the conventional way is via 'sevag method for deproteinization'. Please make simple google search using the keyword 'methods of deproteinization'. The following sample documents may help. My Regards
10.4028/www.scientific.net/AMR.340.416
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Chitosan is a natural biopolymer with antibacterial properties and the solution of chitosan is prepared in acetic acid. So, has acetic acid any effect in contributing towards the antibacterial behavior of chitosan?
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Based on the following link it was observed that chitosan water-acetic acid systems show the highest antimicrobial activity due to the highest chitosan charge density, compared to the mixtures with lactic and citric acid.
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I obtained an EIS data when I am doing research on biopolymers for corrosion inhibition. But I can not find a good fit of equivalent circuit. Could any body help me with it?
I have attached the data file in which the first column is the frequency, the second column is the Z' and the third column is the Z''.
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Could you provide more details about your surface morphology ? ... Is it only a metal covered with this biopolymer ? ... The choice of an equivalent circuit depepnds strongly on what is happening on your surface (electrochemical and physical phenomena) and the state of your surface (porosity, coating, protected and unprotected areas ... ). Your data is corrected for the ohmic drop or not ?
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I am relatively new to DSC. Recently, I ran DSC on starches but always got this broad endothermic peak which I could not explain. Please see the attached isotherm of a starch sample and my method is listed below.
1: Equilibrate at -50.00°C
2: Ramp 20.00°C/min to 220.00°C
3: Mark end of cycle 0
4: Isothermal for 5.00 min
5: Ramp 5.00°C/min to -80.00°C
6: Mark end of cycle 1
7: Ramp 15.00°C/min to 200.00°C
8: Mark end of cycle 2
9: End of method
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Thank you all for your answers. I am running an isothermal experiment to confirm if the peak is indeed coming due to the moisture loss.
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Hello, we want o make biopolymer composite wires using 3D printing (using our solution and not a ready filament of course) and I wonder which biopolymer or even a plasticizer is recommended in order to get ductile wires. Most of what we produce is brittle wires for now. Thanks in advance.
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You need to be very careful with your selection because of extractables and leachables. It depends on your application (patient contact/long term vs short term). Maybe take a closer look at some of the USP Class VI or ISO 10993 rated Polyurethane based photopolymer resins but you might need to use a top down printer to reduce the need for supports depending on the length of the wire and overall geometry. These usually contain some degree of PEGDMA. Also be careful of what type of photointiator you are planning on using.
The end result after curing is typically a polymer with low molecule weight photolites left over that can migrate easily out of the polymer itself after curing and through skin, food packaging and other similar examples. A lot of work is being done to reduce extractables and leachables but applications such as long and or short term skin contact (intact skin vs rating for contact with mucosal membranes) has been successful if you look around at some offerings from some of the larger 3d printing names in the industry.
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Hello all, I am looking for a model drug to encapsulate into a biopolymer. It should be soluble in acetone but it should not dissolve in ethanol. I will appreciate it if you have any suggestions.
Thanks in advance.
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Hi, Elena. Retinoic acid is soluble in both solvents, but it is more soluble in acetone. I hope it helps
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So far, when I looked on molecular docking papers, it often involves using a protein as the receptor molecule, with ligands like another protein, nucleic acids, or small molecules. I have also found the application of RNA or DNA as the receptor molecules, docked against another RNA or DNA, and small molecules. However, I never (yet) found a paper referring of using other polymers as receptor molecules, like lipid or nanocarrier polymers (like chitosan or cellulose or even carbon nanotube). Is there a reason that nobody does that? Or some research groups have already done that? I am just curious.
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These things are already mentioned in many papers. We recently did the same analysis against SARS CoV-2
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Most of the 3D printing resins are synthetic chemicals. Is there any biopolymers to replace resins. If so kindly share some lietrature and suggestion for using biopolymers for 3D printing
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Dear Sudhakar M.P , your definition of biopolymer is not clear. Biopolymers can be divided into bio-based polymers and biodegradable polymers. Bio-based polymers are produced from biosources and can be biodegradable or not, for example, starch or bio-based PE. Similarly, biodegradable polymers can be either bio-based or fossil-based, for example, PBAT is fossil-based while PLA is bio-based.
Now, come back to your questions, I think PLA has been used extensively in 3D printing and PLA is both bio-based and biodegradable.
Best regards,
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Anyone tell the current trend in edible films and coatings? Hydrogel can be used for making films
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Dear Arjun Arulvel, the following chapter deals with the latest progress in this area. My Regards
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The Flory-Huggins theory (1942) has been widely used to account for the mixing energy between long-chain, flexible polymers (e.g., rubbers) and solvents. Can it be used for semi-flexible and rigid biopolymers like actins, microtubules, fibrins, and collagens?
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I am blending PBAT and PLA using extrusion machine. However, the PLA/PBAT blended pellets start to agglomerate, and fail to pass along the screw, as soon as I introduce the pellets in extrusion film blow machine! Is this pellets agglomeration issue common in PBAT~based blends?
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If I understand correctly, you already mixed the two polymers and obtained the pellets of that blend. Your problem is how to avoid the agglomeration of the pellets of the blend. I think you need to dry properly the pellets before feeding the film blow machine.
For your answers, you have already tried using dry pellets. It's worked! But, you add CaCO3, too. I think as CaCO3 is a descant, it acted on maintenance of low moisture.
I think your solution is to dry the pellets only.
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Hello, I am trying to find the solution for the adsorption energy calculation of polymer with any of the chemicals or metals, for this calculation, I am using the adsorption locator module of the material studio. Since I am using biopolymer so there are no such reference for adsorption locator is available.
How can we validate these results, or is there any specific adsorption energy range available that validates our result?
Does anyone have done adsorption calculation for chemical-polymer interaction from the material studio?
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Helllo ,
Adsorption energy:
The heat of adsorption (∆H) can be calculated on basis of a langmuir adsortpion isotherm at different temperatures.
The Langmuir isotherm constant is equivalant to equilibrium constant after adjusting the units to mol/L.
Over the conection of ∆G and K and ∆G with ∆H & ∆S you can calculated the energie.
For this calculation you don't need any special software.
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Chitosan precipitation
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I guess it depends on why he needs that chitosan for. According to the literature, the chitosan at high pH will crosslink itself and it slowly increases the solution viscosity, what would be nice for some applications. it also depends on chitosan Mw and %DD
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concentration: 1and 2 %w
Solvent: deionized water
Storage time: 1 or a few days
Also a layer of mold can be see on it.
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Labile H are lost.
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The material is a biopolymer (biomass) The broad peak I think is an OH peak suggesting an intermolecular hydrogen bonding interaction normally observed in homopolymers and copolymers. but the shoulder around 3249 I got no explanation.
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Hi.
I believe that, if not an artefact, peaks at 3249 cm-1 can typically be explained by the presence of clusters containing significant amounts of three- and four-coordinated water molecules. However, it's been long since I worked with FTIR so double-check this.
Cheers!
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I am trying to dissolve chickpea protein isolate in water but it's not soluble even with raised temperature and constant shaking. Can anyone please suggest the appropriate method or solvent other than water in which chickpea protein isolate gets completely soluble.
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i prepared 1%wt and 2%wt sodium alginate solution with 9 pH and 0.5 molar copper sulfate.
by adding alginate solution to the electrolyte (CuSO4), it is expected to have copper alginate gel in bead form. but i gained very thin very loose small film.
and by adding the electrolyte on the surface of the alginate solution, it is expected to have a thick stable membrane of copper alginate gel that will stay on the surface, but my membrane sinks in alginate solution slowly.
my main purpose is making capillary copper alginate gel.
thank you
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Dear Raheleh Ebrahimi many thanks for asking this very interesting technical question. I just came across two potentially useful articles in which the preparation of capillary copper alginate gel has been described in detail. In this context please have a look at the following links:
Gelatinized Copper–Capillary Alginate Gel Functions as an Injectable Tissue Scaffolding System for Stem Cell Transplants
Also please see:
Modeling capillary formation in calcium and copper alginate gels
Unfortunately these articles have not yet been posted as public full texts on RG. Please see if you can access them thropugh your institution. Alternative you could request the full texts of the papers directly from the authors via RG.
Good luck with your work and best wishes!
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At the moment of meassuring a polymer viscosity which one would you recomend? reomether, digital viscosymeter or glass viscocymeter.
It's for a biopolymer in solution that's is undergoing electrospinning.
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Dear all, since it is concerned by electrospinning, knowing the MW and the range of viscosity/concentration are essential for the electrospinnability. Capillary viscometers are nowdays fully automated, the operators errors are at least significance. So, I recommand an Ubelhode viscometer. My Regards
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what are the effects of the Simulated Body Fluid (SBF) corrosion solution on the stress and Elongation of biopolymers?
Best regards.
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Bioplymer alone or as a coating on top of a metal? Is metal corrosion involved?
Like coatings in general, water uptake is a first point to look at, changes mechanical properties as well.
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RAMAN SPECTROSCOPY?
MS SPECTROMETRY?
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Dear Elizabeth Espinoza,
Like an answer from Malairajan and Ramachandran, the biopolymers such as cellulose, hemicellulose, and lignin most need to isolated before tested.
If possible you should try both as Raman spectroscopy (RM) is provided molecular fingerprint profiles and functional group information and, Mass spectrometry (MS) is a method used to detect the molecular weights and structural information.
These two resources could be the more suitable information as references to your question.
2. Ali, A., Abouleila, Y., Germond, A. An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects. J. Vis. Exp. (155), e60449, doi:10.3791/60449 (2020).
Best Regards,
Virak Sorn
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In classical biotechnology, three stages are distinguished: pre-fermentation, fermentation, post-fermentation. Typical equipment used in biotechnological industries is known. Are there any features in the hardware design of biopolymer production, such as proteins (enzymes), polysaccharides (starch, cellulose), lipids (lipids of microalgae)?
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For thickening polysaccharides, like xanthan, mixing to ensure gas exchange is the limiting factor. At late stages, the injected air tends to rise in huge bubbles with very little exchange.
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Hello all,
I have a two graph ( TGA and DSC) of a biopolymer that I see decomposition starts around 170C. However once I run the DSC I do not see any melting or crystallization peak. Why?
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The crystallization process is complex, especially biopolymers, and depends on additives, as well as on heating and cooling time, so there is sometimes no support between the two characterizations.
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I want some information specially some papers about chitosan biopolymer and the industerial methods to get it from shrimp shell
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Please read chapter ir chitin chitosan writen by boukhlifi fatima
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I would like to know if the properties of a polymer impact on the size of the particle it forms. I'm working with different polyssacharides (alginic acid from different seaweed), which are precipitated by the exact same method. Is it to be expected that the mean particle size of the polymers are different (because of molar mass, polydispersivity, monomers ratio, polarity - one of them has high hydroxyl content -, branching...)? Or is the particle size normally an exclusive function of the process and not the chemical nature of the material?
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Dear all, chains architecture influences to a great deal the spatiale arrengement and close packing. Presence of net charges, stiffness of the main backbone, and bulky side groups, all contribute to affect particle size and shape. In addition to structural parameters, preparation techniques of nanoparticles also influence the size and shape. It is generally agreed that anti-solvent previpitation technique is the most simple and efficient technique to produce nanoparticles with average size ~200nm with good size distribution. My Regards
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I am looking for polymers/biopolymers with high hydrophobicity and high gas permeability. Can any one recommend any types of polymers/biopolymers?
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Hi Niloufar,
Did you try PDMS? Its hydrophobicity and air permeability can be easily tailored; and may meet your requirements.
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I wanted to know about the journal with a high rate of acceptance and sci index.
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Sanjay Kumar , there is a journal called "Polymers" among MDPI journals, it is sci indexed and has a relatively short peer review process but it is open access (APC is required), in case you are interested.
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Dear Researchers,
Please, which papers, sites, tools, or programs you recommend to use in the design and selection of the best materials for prosthetic leg liners?
Regards,
Akram
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Dear Dr. Akram Jassim Jawad ,
in addition to the answer of Dr. Abdelkader BOUAZIZ ,
-a Silicone liner provides high stability and good adhesion if your limb has a lot of soft-tissue. ...
-Polyurethane has a unique ability to flow away from high pressure. ...
-copolymer is soft, cushiony and highly elastic, offering good protection for amputees with sensitive skin and/or lower activity levels.
For more details, please see at:
- What materials are used to manufacture prosthetic liners?
- All About Prosthetic Liners: Part 2 Choosing the best material.
Best regards, Pierluigi Traverso.
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I tested several non-traditional soil stabilizers (e.g. ligninsulfonate, biopolymers) with two different concentrations. The standard Proctor test showed that the additives reduced the OMC and increased the MDD of the soil. Further, the data indicated that an increase in concentration reduced and increased the MDD, respectively, decreased and increased the OMC. How can this behaviour be explained?
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its simple....
grain size changes
flocculation occurs
surface area change is reponsible
voids etc get affected
and similar affects....
i have just summarized the main affects of chemical adiditives on soils..i hope this helps u to undrstand better...
regards
wani
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What chemical bond is created by the Boron nitride/biopolymer on copper substrate to prevent copper deterioration? kindly give an explanation.
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Welcome!
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i want potassium nitrate to be get crosslinked to biopolymer..so weather pot.nitrate will be partially dissolve in ethanol or not?if yes den weather crosslinking will be done in partially dissolve solvent?
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On the matter of precipitation of the potassium nitrate assisted by methanol addition ― cf. German Patent 406,413.
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I have a liquid polyanhydride that is not soluble in water made from succinic acid and ricinoleic acid and I need to make it a hard gel. Investigating I found that it is possible to do this by crosslinking, however, this is carried out with polymers such as cellulose or dextran and crosslinkers such as citric acid or glutaraldehyde are used, which are soluble in water.
My question is whether it is possible to carry out crosslinking using these water soluble agents, and if not, what crosslinking might serve and what method of crosslinking would be appropriate?
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Dear Ricardo Cedeño, why not trying a mixture of Solvents (water+solvent), the second solvent should be good for the polymer and at the same time miscible with water. If this is possible try different proportions. My Regards
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I have been trying hard for a month to observe some definite structure of the biopolymer which was synthesized by our lab. The irony is it cannot be dissolved in any organic solvent and we are left only with some aqueous buffer for our studies.
Since SEM requires solid samples i highly doubt to see anything under it except for some random aggregates.
Even in regular TEM I can only see indefinite aggregations of polymer. I have tried staining as well which in some instances effected polymer structures, like i have seen some nano vesicles but those were not the representative of the sample.
Please dont recommend cryoTEM because we are struggling hard to get the dates, but chances are not likely.
Need Help!
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I have a liquid polyanhydride that is not soluble in water made from succinic acid and ricinoleic acid and I need to make it a hard gel. I think I can cross-link using ethylenediamine, but I'm not entirely sure. How can I cross-link with ethylenediamine or some other substance?
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Hi Stjepan Krešimir Kračun;
I completely agree with you, methacrylate and acrylate monomers form strong, hard polymers with excellent dimensional stability. However, the hydrolytic instability of the ester bond is very advantageous for certain medical applications (degradation of these polymers) such as: hydrogels for angioplasty or drug delivery.
With my best regards
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I would like to lubricate the PLA with a plasticizer while without compromising the PLA compostability.
Your suggestions/comments are highly appreciated in advance.
Cheers
Raj
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Dear Rajendran,
If you are looking for a “solid” plasticizer, PEG with molecular weights of 1500 or higher, could also be a good alternative for some specific applications requiring PLA with improved toughness and ductility. For more information, I strongly recommend taking a look on the following reference:
Alexandre Ruellan, Violette Ducruet and Sandra Domenek, (Chapter 5) Plasticization of Poly(lactide), in book: Editors: Alfonso Jiménez, Mercedes Peltzer, Roxana Ruseckaite, Poly(lactic acid) Science and Technology: Processing, Properties, Additives and Applications, 2015, https://pubs.rsc.org/en/content/chapter/bk9781849738798-00124/978-1-84973-879-8
Good luck and best regards,
Marius
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Dear all,
I have coated MnCO3 microparticles with different biopolymers through Layer-by-layer approach.
I am not sure how to analyze the sample under SEM.
I fear sputtering might damage the coating.
My sample is in powder form.
Thanks in advance
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If you use KBr pellet you might have scattering problem using IR if you have microparticles but not if you use a micro-Raman. You can always use ATR-FTIR to avoid the problem. This would tell you if you have polymer in the sample (not necessary if that polymer is where you want it to be).
Maybe you could use backscattering SEM to check if you have organic on the Mn particle surface or use a transmission technique (TEM or optic microscopy if both particles and shell are tiny or big enough).
Also an Mn quantification might help to know how mich of your final mass is MnCO3 and how migh is possibly polymer.
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Other than extraction of PHA from bacterial cells are there any other methods to quantitatively analyse PHA
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Hello, we used a range of methods in this paper:
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My high school Bio-Inspire Design students are trying to develop a waterproof/resistant biopolymer film for marine applications. Their curious about PLA and wonder if there's a low tech way to make it without the use of many chemicals or fancy equipment.
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Dear John,
Nice objectives, but a complex and hard work to be realized!
I believe that a strategy with the main goal to produce competitive PLA films going from lactic acid, could imply some advanced skills and a reach experimental program (I will not develop the details for the different steps). On the other hand, I totally agree that some general knowledge & more information will be helpful to support better this project.
Based on my experience, I would like to suggest focusing the first works on the fabrication waterproof/resistant biopolymer films using as raw material some commercialized PLA grades. You will see that is not very easy to arrive to find the best alternative as Proof of Concept!
Good luck to you/your students in realization of this study,
Marius
PS: For eventual help:
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My biopolymer film is not sealing it is becoming chared or it is pealing out weather can I use any food grade glue to stick them
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Certainly it could be a possibility, alternatively adjust the temperature and decrease it, alternatively utilize ultrasonic welding.
Please keep me posted with your success.
Kind regards
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Interested in polymers that are soluble in small organic acids such as citric, etc. I know that citric acid is used as a cross-linking molecule for making biopolymers. But am interested in polymers that are soluble in 2C and 3C organic acids.
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One such pharmaceutically important polymer is chitosan
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For my thesis research, first, I mix PLA (solvent: chloroform/methanol) and PCL (solvent: chloroform/methanol) for 2-3 hours. After that, I want to mix PLA/PCL with PMMA (mW 350.000 solvent: ethyl acetate). How long does it take to mix PLA/PCL with PMMA perfectly? Thank you.
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Hi, different polymer blends may require different durations. However, such mixtures are usually made overnight (24 hours). You should be careful in choosing the solvent. Solvents must be compatible with each other.
You can review the research below.
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Natural gums such as Arabic gum have low molecular weights. However, they are available as natural products. Is it possible to add a chemical to form stable polymeric gums with a very high molecular weight just like Polyacrylamide that is used in EOR applications?
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Dear Sir,
Thank you very much . Can you guide me the procedure how can we cross link the xanthan gum with ferro chrome sulfate and Adipic acid .
Regards,
C. Paul jeyaseelan .
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Greetings! I have a research where I dissolve PLA in chloroform:methanol (3:1) for 3 hours and also PCL in chloroform:methanol (3:1) for 3 hours too. After that, I have to blend those two polimers together with magnetic stirrer. The question is, how long does it take to blend the solution of PLA and PCL with magnetic stirrer around 300 rpm? It would be better if you could refer your answer with journal. Thank you in any advance.
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Hi Evangelina,
I do not have a reference ready, but my first hand experience tells me that your two solutions should mix quite well in a short time. I would expect to obtain a homogeneous blend after 2 hours at 300 rpm. Just make sure to obtain a clear and transparent mixture: this assures you that the polymers are well dissolved and that you have one single phase.
Also, if you want proof that the blend is single-phase and stable, just mix for 2 hours and then stop, let rest for a few hours and check for any separation/precipitation.
Hope this helps,
Lukas
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Hello,
I made 2% xanthan gum solution and measured its viscosity while increasing temperature of the solution.
I guess viscosity of the solution should be decreased while heating, due to degradation of the polymer, according to the previous researches.
But I found that viscosity of my xanthan solution had increased continuously while heating and then suddenly dropped down quickly at 95'c.
Do you think it's normal to have the viscosity increasing while heating??? I want to know why it increases....
Please help! :"(
(+) I made the solution with 80'c water while stirring vigorously and homogenized for 15min at 5000rpm. So I assume all the dry xanthan powders were solublized enough.....
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It has been reported that xanthan in water undergoes a conformation transition when heated. At high T (and low ionic strength) it adopts the conformation of a disordered coil, at low T it adopts an ordered conformation (single or double helical, this is a matter of debate). Transition temperature Tm has been reported at 55 degree C (R.O. Mannion et al., Carbohydr. Polym. 19 (1992) 91-97). For the conformational transition, see E.R. Morris et al., J. Mol. Biol. 110 (1977), 1, and I.T. Norton, J. Mol. Biol. 175 (1984) 371. This may well be the cause for the phenomenon observed by you.
There is a rather vast literature on xanthan conformation, especially in what regimes random coil, single and/or double helical conformations prevail. As I am retired I have no access to this literature to advise you in more detail.
Because of these transitions, the preparation of xanthan solutions needs rigorous standardisation.
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Any recent research on biopolymers application in surface protection against miro & microorganism and algal deposition?
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I can suggest the recent work my group performed on chitosan:
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I am looking for a good book publisher for one of my book chapter related to biopolymer hydrogels having scientifically a broad scope and also a ISBN. If someone has experience in the same or related area or any general advise is more than welcome!
Thanks
M. Khan
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Fatty acids are known to act as building blocks for various biopolymer synthesis. Can we use microbial biodiesel for such purpose?
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Thank you all Karakka Kal Abdul Khader ,
Sullivan Lee
and Marwan Farhan
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I have synthesized Phthalated chitosan, now want to calculate its degree of substitution, is their any method available for calculating degree of substitution by UV spectrphotometry or Tirimetry????
Please help me out.....
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