Biological Psychology - Science topic
Behavioral neuroscience, also known as biological psychology, biopsychology, or psychobiology is the application of the principles of biology (in particular neurobiology), to the study of physiological, genetic, and developmental mechanisms of behavior in human and non-human animals. It typically investigates at the level of nerves, neurotransmitters, brain circuitry and the basic biological processes that underlie normal and abnormal behavior.
Questions related to Biological Psychology
I would love to receive some recommendations from experts in regards to the topic, whether there are valid findings in research on biological markers for anxiety disorders. I am trying to gain some stable insight and be able to argue in favor of the notion, that no anxiety disorder "comes from a malfunction/sickness of the brain".
Thank you in advance!
Galvanic Skin Response (GSR) varies from person to person. How to set a baseline for GSR considering parameters such as probe-type, probe-material, skin moisture level, blood pressure, temperature and stress-level which can affect the result?
To Whom It May Concern,
To Whom So Ever Interested..
We are a research group from different countries (Palestine, Jordan, India, Malaysia, Germany, Turkey, UK, USA) who are interested in investigating personality traits as well mental disorders from different perspectives, biological, psychological, and socio-cultural domains.
For those who find themselves having the potential to collaborate in data collection (in some cases already we have a plenty enough bulk of raw data), surveying and reviewing the related literature reviews, writing per the APA style, analyzing, interpreting results and drawing conclusions, etc..
Please, send your statement letter of interest to: email@example.com, and kindly determine where you are most fitting to play a role in such a research project.
Wael M. F. Abuhasan
Slow breathing, usually at frequency of 0.1 Hz, is a method of relaxation and supposed to increase parasympathetic activity. Heart rate variability is used as a marker for autonomic response to such intervention. In the frequency domain of HRV analysis, the HF power is considered as a marker of vagal modulation of cardiac activity, the LF power for sympathetic influence with parasympathetic component, and LF:HF ratio as sympatho-vagal balance, though with controversy.
There is a concern about how to interpret frequency domain of the HRV analysis if respiration frequency is variable (not controlled). For example, as showed in the attached file, while time domain analysis of HRV indicates increased vagal activity in response to slow breathing (increase in SDNN, RMSSD, NN50, and pNN50), the frequency domain is complex; LF (and LFnu) and the LF:HF ratio are higher in slow breathing compared with normal breathing and also compared with breathing at frequency of 0.2 Hz. Also, HF is not significantly different between slow breathing and breathing with frequency of 0.2 Hz while HFnu is lower in slow breathing.
How frequency domain of HRV must be interpreted when the intervention itself is changing the frequency of respiration? Is the time domain a better analysis of autonomic response in such case?
I have some EDA data from a colleague's project that I want to analyze. Looking into the data, I discovered that the sampling rate is relatively low - it is only 2 Hz. However, the literature I read suggested that the sampling rate should be at least 200 Hz. So, it seems the sampling rate is not high enough for analyzing the phasic components of EDA. Still, as I am completely new in the field of EDA, I would like to ask for your opinion:
Can I still conduct meaningful analysis of phasic SCRs?
Hi, I am a german university student (business administration and psychology) and I am going to write my bachelor thesis.
I would like to research a correlation between stress and the language. For the following therms I need your help:
- differently option for stress induction
- or unsolvable tasks for stress induction
- or questionnaire for stress induction
I know about the trier social stress test and the socially evaluative cold water stress test, so I need other options. The best way for me is, to have a computeraided stress test.
I hope you can help me and make my student life a little easier :-).
I now have created a compact version of the ``theory of everything'' I am developing since several years, also including the biological and psychological extensions dealing with human body, human soul, and human mind, in the latter case, comprising mental disorders just like drugs applied to treat mental disorders. In particular, in the last chapter (``On the Quest of the Actual Nature of Being''), I there present formal boxes which compactly elucidate the central feature of all this, namely the interrelation of forces and fields in the context of macroscopic systems and microscopic systems, naturally incorporating gravitation, electromagnetism, and self-interaction, by way of example, also presenting the way to the notions ``weak interaction'' and ``strong interaction'' as used in quantum field theory. Please consult the copies ``Understanding Nature Truly'', part one, two, and three presented in RG in the context of my projects
``Theory of Everything'' (part one) and ``Human Soul as Mathematical Object ...'' (part two, three). Do these formal boxes contain enough information to show that the ``theory of everything'' I am developing since several years indeed works? Do these formal boxes contain enough information to show that ``theory of everything'' is not what people so far a looking for, but something completely different? Do these formal boxes contain enough information to show that exactly this is the problem preventing that people realize the way I am going as the right way?
Respiratory Sinus Arrhythmia (RSA) appears to relate to vagal tone. Perhaps loss of RSA is a marker for PTSD.
I hope to measure whether a variety of mind-body interventions for traumatized populations has an impact on RSA. It would also be interesting to ascertain if change in RSA correlates with clinical improvement.
This will be for adolescents and adults.
I am looking for insights as how to measure RSA in a research context. This includes whether commercially available Apps are acceptable, what would be the cost, etc.
There's plenty research literature on the topic with adult subjects, but I find it difficult to find any studies that would report using the technique (or other HRV Biofeedback breathing) with peadiatric population.
A vasovagal response may be observed with needle phobia upon insertion of the needle therefore reducing blood pressure, heart rate, stroke volume and cardiac output.
However a study (Finsterer, 2004) showed that needle EMG did not affect blood pressure or heart rate.
Can anyone provide any more evidence or explanation of what would happen?
I came across this : https://www.cooking-hacks.com/airflow-breathing-sensor-mysignals-ehealth-medical
but not sure how good it is (it looks DIY hack-y) to use this as a gold standard. We are interested in using EMG to detect breathing , and need a reliable device to measure ground truth. Any suggestion would be highly appreciated!
I normally used a DAM 50 amplifier from WPI but it broke. We have an Axopatch 1D in the lab and I heard it could be used for field potential recordings (e.g. cerebellum slice from mice). Could someone help me on how to configure the Axopatch amplifier for this purpose?
I have found several stains for developing granule cells, but no distinct markers for mature ones. I could just use NeuN and use location, but would prefer a specific marker. Thanks
I am planning an experiment in which I want to compare baseline heart rate variability before and after an intervention. For saving the participants time I want to keep the ECG-recording sessions as short as possible. Yet, i still want data from which I can make a reliable conclusion about the participants baseline HRV.
I would like to analyze time- (SDNN, RMSSD) and frequency parameters (LF, HF, LF/HF ratio but not VLF).
So, how long should the recording be at least? And do you know of any literature supporting this?
I was speaking with our University's vet and she mentioned that live decap is the better route to take if you're planning on doing any histology after death. Does anyone have any further information on this/any sources that show this?
Is there any report on effect of blood pressure (SBP and DBP) on short-time perception/short-interval time estimation, a cognitive attribute in human?
A colleague and I have been trying to decide which NIRS system to purchase and hope to get advice from those with experience. We have no experience with NIRS and have lots of ideas for how it may be used in our psychology/behavioral neuroscience department (we are not purchasing it for one particular research goal). We’d like to be able to record from any area of cortex (not just prefrontal) and we’d like something flexible and modular so that we can scale up when we get more funds. We think we’ll have 75 - 100k to work with for now. Do you have suggestions based on your own experiences with particular vendors and systems? Thank you.
From my understanding, under increased metabolic demand, heart rate (HR) and respiratory rate (RR) increase (i.e. they are positively correlated). Is this always true?
1. Is there any metabolic situation where HR would increase but RR would not (no correlation)?
2. Is there any metabolic situation where HR would increase and RR would decrease (HR and RR are negatively correlated)?
Are there guidelines or instructions posted (or published) on how to best extract respiratory parameters during amusement/humor tasks? Specifically, I am having trouble extracting respiration rate from tasks where laughter is involved. The signal is noisy, and the variability in respiratory depth makes it challenging for me to meaningfully isolate when a breath ends and another begins. I only appear to encounter this issue during amusement tasks.
I have attached a picture of a representative example of the issue.
I used Open field plus sucrose preferential. However, I receive this question when I'm presenting my stress-depression animal model. One of the questioner, a professor ask me this as he is using a substance that greatly affected the mouse prefrontal cortex and the mouse barely move.
I am looking for questionnaires and tests that apply to clinical assessment of novel psychoactive substances addiction. Is there visual analogue scale for craving?
The induced gamma synchrony has to do with the inferior frontal junction and other brain areas. How does consciousness is "produced" by this phenomenon and what this penomenon is about?
For my experiment participants are assigned to two different groups while they to a Go/NoGoTask. I recorded the EDA via electrodes attached on the left hand and now I wanted to compare the SCL between the groups.
Of course, I could just compare the "raw" SCL data, but shouldn't I do some kind of range correction too? But if I do that e.g. following the recommendation of Lykken and Venables (1971), wouldn't I dimminish any group differences?
The animal environment is full of attractive and dangerous sources which influences the behavior of it. It seems, Lewin's field theory could describe the multiple sensorial inputs as forces to determine animal behavior. Not only bacteria, where the forces could be interpreted as gradient of substrate concentrations, but also in higher animals with a developed cerebral system follow this field of forces.
Previously to understand the concept of health disease medical model is applied, where health professional concerned about the disease, diagnosis and drugs, but now this model is replaced by the bio-psycho social model, in which we should include the psychology and social factors along with the biological as it is also the part of the nature.
Hi! We would like to present a series of affective pictures. What is the best time interval between two pictures so that we might analyze skin conductance responses in the right way? We would like to change from one picture to the other as quickly as possible to maintain the interest and provide constant affective stimulation. Thus, we are mostly interested in minimal acceptable intervals. What literature guidelines would you recommend? What is your personal experience? I will be grateful for any hint. Thank you!
I am looking for literature about resting energy expenditure, activity-induced thermogenesis or total energy expenditure in anorectic subgroups! Are there papers reporting about differences between bulimic and restrictive anorexic patients in energy expenditure? Does anybody has recommendations? (P.S.: I have found the papers of Kaye 1988 reporting about differences in bulimic and restrictive anorexic patients during refeeding) Thank you for your help!
Hello! I have recently started collecting data using a Brain Products EEG system. I have been analyzing ERPs using the free software ERPlab. I also collect heart rate data during sessions using the Brain Products blood pulse sensor. I would like to analyze the HR data, preferably in a way that examines heart rate variability. I know it is possible to do so with Brain Vision Analyzer, however my lab does not own this software. Does anyone have a recommendation for how I can analyze these HRV data? Preferably using a free software package (I have access to matlab, R, and Python).
Thank you so much!
There are some excellent open access resources available for teaching psychology such as NOBA Psychology: http://nobaproject.com/
Would anyone have any similar recommendations for teaching biological psychology and cognitive neuroscience in particular?
I will also be testing the mothers but believe saliva to be the best way to do this. I am thinking that urine samples may be a way forward. Does anyone have any thoughts?
I would like to record ECG, EMG and respiration (with a chest belt) data in humans and have a general question about the filter settings. The recommended filter settings for my study are ECG 1-35 Hz, RSP DC-1 Hz and EMG 10-500 Hz. One expert recommends to apply the filters real-time during acquisition and the other one to apply filters after data acquisition. I searched former literature and couldn't find a general suggestion. Is there any disadvantage in applying post-aquisition filters and no real-time filters during the acquisition?
Thanks for sharing your thoughts and suggestions.
There is an expectation that understanding the neural substrates of mental disorders will revolutionize the field of psychiatry, in terms of improving diagnostics and treatment. However, the clinical value of neurobiological research into mental disorders has so far been minimal.
What are your opinion on this matter?
Do you agree that an understanding of the biology of psychiatric disorders (genetics, molecular, brain circuits etc) will lead to improved diagnostics and treatment, or are the expectations of a ”revolution” exaggerated?
I’m interested in hearing your opinions on this matter.
We have observed a large noise increase in facial EMG recording when skin conductance electrodes (GSR) are applied. This seems to be caused by the fact that GSR amplifier produces currents that are captured by fEMG sensors. This is a serious problem because this noise (of about 200 microVolts) is usually stronger than the electrical signal from facial muscles. I wonder whether you might provide me some feedback whether you encounterd the same problem while simmulatenous EMG and SC recordings, and how you managed to handle it. We use ADInstruments Powerlab with BioAmp and GSR Amp. Thank you!
I am looking to develop a Social and Cultural Complexity Quotient. This will be built on Prof Clare W Graves' Biological, Psychological, Social System framework and include introvert extrovert, analogue digital thinking, various change states as a core. To develop the quotient further I feel I would need to include life conditions. Has anyone come across Complexity Quotient being used in this Social and Cultural settings? Welcome suggestions and ideas.
If a person fills out scale A multiple times, can we include all their attempts at that scale in calculating internal consistency or do we only have to select one attempt of that scale (e.g. the first attempt)?
My background is in mental health, however I am new to the study of asthma. What are the key conversations regarding the interaction of these two elements should I get myself up to speed on?
In my experiment I would like to include a questionnaire or implicit measure that would allow me to distinguish among intrinsic, extrinsic and reputational pro-social motivation.
This concept was developed by Bénabou and Tirole (2003, Available at: http://idei.fr/doc/by/tirole/incentives_prosocial.pdf).
However, I have not found any measurement that could be applied in an experiment on pro-social behavior.
What would you recommend?
Thanks a lot in advance!
I am currently analysing data from an fMRI study, with a 2x2 between-within design. Patients vs controls reflect the between factor, and congruent and incongruent trials reflect the within factor (this is a Stroop task).
After seeing an interaction effect between the two factors in several brain clusters, I wanted to extract the beta-weights from these clusters to explore the underlying effects.
I used Marsbar to extract the raw beta-weights from congruent and incongruent trials, separately (so no contrast between conditions performed), and plotted the results for my two groups.
Many of the resulting beta-weights are negative, and I wonder what this means? Does it reflect a sort of 'deactivation'?
Any input will be highly appreciated!
A lot of us are investigating the pathophysiology associated with mental disorders. One popular method is fMRI, which would be one example of measuring macro properties of the brain, at the regional / circuit level.
I have conducted an fMRI study comparing recovered anorexia nervosa patients to healthy controls on an emotional stroop task. The task consists of fearful and happy faces, overlaid with either the word 'fear' or 'happy'. Thus, a given trial can either be congruent (face and word match) or incongruent (face and word mismatch). The task was to designate if the face was happy or fearful, ignoring the word. Reaction time data showed that it takes longer to respond to incongruent trials compared to congruent trials, which we expected.
However, the fMRI analysis shows that, for the control group, participants had more bilateral amygdala activation during congruent compared to incongruent trials (as shown by the extracted beta weights from left and right amygdala). I expected more amygdala activation for incongruent trials (thinking that an emotional conflict conveys more saliency). I am struggling to understand our observation.
Does anyone have any comments regarding this finding? All comments are highly appreciated!
We are designing a neuroimaging study to test hypothesised circadian moderation of reward function in humans. Seems like our hypothesis is best tested using resting state methods, ideally with the hypothalamic suprachiasmatic nucleus as a 'seed region' to investigate correlations with brain reward centres (particularly ventral striatum).
I understand that small, deep brain centres are difficult to image.
We know about the effects of long winters and dark days on human psychology. Is there SAD in reverse ? What treatment do people get when depressed in summer,lose their energy, cannot take the heat even warm weathers and sunshine (other than photo-phobia in general)and rather want to hibernate when spring comes until fall ? (like me!)
Many studies have shown a high comorbidity between depression and anxiety. Is it more likely that one of these conditions causes, or makes more likely, the other? Or do both depression and anxiety arise from a common source, either genetic or environmental?
I need resting state multi channel EEGs or fMRI recordings from people with bipolar depression and healthy control
For those of you who don't know about it, you can find information here: http://www.nytimes.com/2013/05/07/health/psychiatrys-new-guide-falls-short-experts-say.html?nl=todaysheadlines&emc=edit_th_20130507&_r=1&
Hi, do you have the idea to answer this question?
"When monkeys with Kluver-Bucy syndrome pick up lighted matches and snakes, we do not know whether they are displaying an emotional deficit or an inability to identify the object. What kind of research method might help answer the question?"