Biodegradable Polymers - Science topic

I am looking for possible reason why some organic acids are successful for collagen electrospinning and others are not exploited at all, as food grade solvent is a concern. Some explanation for possible criteria of selection of solvent. 

Polymers undergo degradation by weathering ( UV-light, oxygen & moisture effects outdoors low temperatures ) hence the use of stabilizers.

But i could not find studies on this problem or solutions for the case of biodegradable polymers. Are the solutions known for PBS, TPS & PHA and their blends ?

Hi

I have done the removal of heavy metals from the aqueous solutions through batch experiments. I observed that with increasing the concentration adsorbent (g) the % removal of heavy metal has increased almost 100% but the adsorption capacity (mg/g) has decreased. Are these two entities are inversely related to each other? While optimizing the experiments which factor should be considered more important % removal or adsorption capacity w.r.t. manuscript as well?

Thanks for your response in advance.

What works describe these methods? Thank you!

I have PLA blended with some process aids. I want to understand the stability of my blend with respect to temperature. Which is why I am thinking I will go for temperature Sweep. But I don't really understand how to make sense of the data in this context.

Edit 1: I understand that as stiffness decreases it means that compound would be a lot more easier to process. But I am specifically looking for any anomalous behavior which can point out a miscible blend from another immiscible blend.

Dear ResearchGate members,

I would like to know if polymers such as Polyvinyl alcohol, Polyvinyl pyrrolidone, Chitosan, Carboxymethyl cellulose, etc. (with a molecular weight less than 40 kDa) have a lambda max in UV-Vis spectroscopy. If they do, how do they not interfere with drug estimation in nanoformulations/nanoparticles (polymer-based nano)?

Thanks in advance.

I have the following queries

1. Which is suitable for determining the polymer blend miscibility-viscometric or solid blended film?

2. which method is superior? Will they provide the same results? Which is the preferred method?

3. Does two method can give contradictory results?

3D printers use various polymer materials and metals. PLA, ABS, TPU, PETG, Peek, Ultem, nylon, Polyamide12, SS316, Ti-6Al-4V, Alsi10mg are some of the 3D printing materials. I need to know the Energy Absorption, Specific energy absorption, Strength, Stiffness of those materials.

Please help me to find the same.

Environmental pollution from microplastic particles is growing rapidly. Consequently, the importance of improving waste separation and recycling systems and the demand for replacing plastic with biodegradable substitutes is growing. Due to the rapidly increasing environmental pollution from plastic waste, it is urgently necessary to develop biodegradable plastic substitutes from which different types of product packaging and also different products can be made.

In view of the above, I address the following research question to the esteemed community of researchers and scientists:

What is your opinion on this subject?

Please reply,

I invite you all to discuss,

Thank you very much,

In the following article, I have presented the results of research conducted on the relationship between sustainable development, the origins and significance of the Sustainable Development Goals, and the essence of sustainable development in the context of social, normative, economic, environmental, climate and human rights aspects, among others. The research also addressed key determinants of human existential security as an element of the concept of sustainable development.

I invite you to scientific cooperation,

Warm regards,

Dariusz Prokopowicz

Can fizzy drinks dissolve the pet bottles? How safer is the recycled polymer materials for same purpose? How better it is to choose upcycling of the polymer over recycling...

How benign is biodegradable polymer to enter body?

What about eatable polymer materials or cellulose based food gadgets?

Hi everyone,

Are there any biodegradable polymers around that can be used to form a shell (containing aqueous system) with high transparency, high permeability ? From what I know nowadays people mostly using alginate to form a hydrogel shell, but I wonder are there any polymers out there that can be used to make either a hydrogel or non-hydrogel shell that is highly transparent and highly permeable.

Hello everyone,

I’m currently searching statistical data about the use of plastic in food packaging and the waste derived from it, but I don’t find first hand updated information about it. Could you recommend me any publication, website or institution where I can obtain information?

Thank you for your attention

In the near future some non-biodegradable materials will be replaced in production processes for other, biodegradable. For example, plastics in the European Union until 2021 are to be withdrawn from packaging and replaced with other biodegradable materials such as paper or packaging produced from food, eg from cereals. But this is just the beginning of the revolution in the development of pro-ecological material innovations. This is only the first step towards the withdrawal of plastic as one of the main factors of littering the natural environment.

Do you know other types of examples already implemented or planned to implement projects to replace plastics with biodegradable materials?

Which biodegradable materials will be replaced in the future by plastic that is being phased out of production?

Please, answer, comments. I invite you to the discussion.

In a stress-strain curve of an FRP composite, mostly it is represented strain in terms of (%) rather than in (mm). Why it is represented in such a way?

Especially pellet/film form of biodegradable polymer types.

Does anyone know of a company that manufactures Poly(L-lactide-co-trimethylene carbonate) Lactide:TMC 75:25?

I am in need of an autoclavable dialysis membrane with a MWCO around 100K Da, but I can only find vendors for RC membranes up to a MWCO of 50K Da. Any input on where to find a supplier would be helpful.

I had studied some methods applied to evaluate the average molecular weight including high temperature-gel permeation chromatography (HT-GPC), MALDI-TOF/MS, viscosity measurement using capillary viscometer. Which methods is the best to identify the molecular weight changes in PE, PET and PVC?

Besides, the intrinsic viscosity's based on Mark–Houwink–Sakurada equation [η] = KMα v, where K and a have different coefficient value according to different solvent and temperature. Do anyone has detailed Table of Mark-Houwink-Sakurada Constants for Various Polymers in Selected Solvents ?

Thank you.

The baseline of PVA jumps suddenly towards higher intensity (on the Y axis) on reaching 200 degree Celsius.

Plastic is now integral part of our life. Plastic industry is growing with a lot many Environmental problems.

We have various options and technologies but each one has its own merits and demerits.

1. Is it possible to ban plastic? The answer may be a big No.

2. We may ban a particular type of plastic? If yes, what type of plastic could be banned?

3. Reduce it use? But the problem will be there again.

4. Recycling is one good option but not cost effective.

5. Biodegradable plastic is one attractive alternative but not practical or may be very expensive?

In such situations what may be recommended?

Poly(ethylglyoxylate) is a biodegradable polymer which has many biomédical and pharmaceutical applications. The synthesis of PEtG is carried out by cationic way. Degradation of this polymer releases ethanol and glyoxylic acid

need good reproducible experiment paper

Hello,

I am a bit confused on whether to follow ASTM D785 (Standard Test Method for Rockwell Hardness of Plastics and Electrical Insulating Materials) or ASTM D2240 (Standard Test Method for Rubber Property—Durometer Hardness) to measure the hardness for PLA and PHAs polymers, or can I follow any of these ASTM standards?

- My understanding is that ASTM D2240 is used for softer/rubbery plastics, but I am not sure whether these two polymers fall under this category.

Thank you for your time. Any replies will be highly appreciated.

Hello,

I managed to run a small blown extrusion line, head diameter 70mm / screw 45mm.

The machine is to be used for extrusion of sleeves from 200 to 500mm wide. Unfortunately, I have a draw resonance problem. I cannot stabilize the balloon.

The head die has a cone that is designed to stabilize the balloon and the air ring characteristic for HDPE heads. (picture attached)

The machine temperatures are set to 140 degrees Celsius from the loading zone to the machine die head.

For the present moment I have only been able to stabilize the balloon for a 200mm wide sleeve, TUR was then 10.43. As soon as I try to blow the balloon to larger sizes the balloon begins to destabilize and there is a resonance phenomenon.

I don't understand what could be the cause of my problems, maybe the die that is designed for HDPE processing is not suitable for PLA?

Regards,

Michael

Project is based on biodegradable materials.

Some find says Henry Ford made it with the oil for resin?

I understand that depending on the size of the fiber, different plastic can be made but there's no recipe.

Carbon Fiber like's is the long fiber entertwined?

Bio-Polymer Pebbles for 3D print is with the short fiber?

Double Usage or Fiber Only cultivar?

What biodegradable polymers could be used as a dispersing matrix in CRF?

What are the oil based inputs for production of bio-polyamides for application in textile sector?

Alginate is an anionic polymer and on the other hand Rhodamine B is a cationic dye. Theoretically these two should be boned by ionic bond. Does it happen? More suggestions and experience are greatly appreciated. Advanced thanks!!

I obtained silver nanoparticles from the crude extract, i want to encapsulate the AgNPs with the biodegradable polymers to proceed my in vitro and in vivo cancer study.

i want to modify this polymer with nano particle and i need a good solvent before anything ...

Everyone know about the non bio-degradable nature of plastic and associated environmental problems. Now new bio-degradable plastic shopping bags have been introduced in the market. How plastic can be bio-degradable?

I done the hydrolytic degradation test for degradable polymer applied for implant. I'm using phosphate buffered saline (PBS) at pH 7. The sample is 3 mm thickness was fully immersed in the solution for 7 month and the weight loss were measured every month. However, there were no weigh loss observed for the samples during 7 month of testing. Is there any specific enzyme that i could used to accelerate the degradation process?

As PLA is biodegradable polymer and obtained from natural resources.so what is degradable life of PLA

Formulation of beads for bone infection.

Could I use lysozyme or lipase? hopefully I can buy from sigma or other chemical company. Thank you

I need a lot of PLGA for experiments without having to pay the steep price for medical PLGA.

Can anyone suggest a cheap biodegradable polymer that can be used as a drug carrier?

Now, we are to find the most suitable biopolymer matrix which are among starch biopolymer alternatives i.e rice starch, potato starch, wheat potato, corn starch etc. Therefore, we have identified 19 selection criteria. We really appreciate your feedback in assigning a weight of importance out of 7  score on  1 -  7 scale (1 being the "Not at all important", and 7 being "Extremely important") for each criterion in evaluating starch alternatives. 

Please click the link below to participate in the Experts' Survey: https://goo.gl/forms/K5bVs1Hq7KIgk0V72 All data collected will be used ONLY for this research. 

We hope to gather feedback from all experts by 9th of January 2019. Your feedback is very valuable and all your cooperation are highly appreciated.

For thesis

I will use Poly(trimethylene carbonate-co-caprolactone) to formulate a drug along with emulsifier like Tween 20, Tween 80, Span 20 and Oil. Please suggest me. Your sincere cooperation to render my research is highly appreciated!

I am looking for some literature on 3D polymer printing in the nanoscale, and I can't find much. Most of the 3D printing methods in polymers go down to a few microns in resolution. Sub micron resolution seems to be achievable only with metal, or metal/polymer inks.

If anyone can suggest some publications, I would be grateful.

How to prepare Biodegradable Polymers from Oils??? Suggest research paper please

I am looking for an overview of approved biodegradable polymer implants (FDA, CE, etc) that are already in the market. 

How the flexion point is related to the mechanical strength properties and degradation of a polymer?

Is it true that all the biodegradable plastics will dissolve in dichloromethane?

Have you ever made your own drug-containing filaments of water soluble/dispersible polymers preferably (low melt temperature (<100 deg C))? Are you using a lab-made extrusion device or a commercially available one? I'm afraid the references I got from bibliographic searches did not include sufficient detail.

What polymers did you use PLA, PGA, PCL, methacrilates any other?

Thanks in advance.

tell me methods other than HPLC LC-MS OR GC-MS ? If possible, give some information about identify of plastic degradation in SSF and LSF using microorganisms kindly help me. Any known microbial groups or biological enzyme can degrade or reduce plastic ?

I am doing swelling test for PCL/PGS electrospun mats, I am using HFIP as a solvent. I found out the the weight of the fibers decreases rather than increases after 2 and 4 hours, what could be the reason?

-In first journal:

Immersing small size scaffold cause only slight increment in the volume observed in graduated measuring cylinder (V2). What is the correct way of performing this test?

-and also:

I used another method in second journal, but my results were more than 100 %!

For example:

P=(W2-W1)/pV1

Where W1 and W2 indicates the weight of the composites before and after immersing, respectively, and V1 is the volume before immersing, ρ is a constant of the density of n-hexane.

W2 = 0.196 g, W1 = 0.020 g, V1 = 0.235 cm3, p=0.654 ……..

P = 115.032 !!!

I have the polyfitic oil which i want to encapsulate with using polymer, surfactant and their mixtures via making an emulsion and further LbL.

I'm searching for non-toxic, biocompatible and biodegradable surfactant and polymer. For polymer I'm going to use polysacharides. But for surfactant can someone suggest?

what is the difference of solvation behavior between non-ionic and ionic polymers/hydrogels in water? for example between poly NIPAM and poly (diethylaminoethylmethacrylate).

This a very severe problem that I am facing while doing my work. I have prepared soyabean oil methacrylate, but the material is getting semi solidify after keeping it sometimes at the cold condition or keeping it at room temperature for few days. The material is probably getting gelled or crosslinked I do not understand correctly. I have checked the solubility of the semisolid matter in every solvent and found that the material is not soluble further. But the time while I had prepared the material, it was readily soluble in any versatile organic solvent. Hence it's a keen request to you to get me some answers behind this reason.

I am using HPMC 3 cps with water and currently using 10-15% w/w concentration.

What is the important parameter that needs to be controlled to get good granules?

My granules always came out as big lumps and fines. When dried in the oven, the big lumps became really hard. Milling causes them to become like sesame seeds which cause weight variations in my tablets.

Thanks

if there is any such polymer would that be available commercially? 

Silk fibroin is a well-known biodegradable material, and there are hundreds of publications about the usage of silk fibroin in tissue engineering, wound healing, drug delivery etc. However, silk sutures are non-absorbable (non-degradable), as indicated in the suture selection guides of all the suture manufacturers.

So... is silk fibroin degradable or not? If it is degradable, why is it used for the non-degradable sutures?

does citric acid decrease the surface tension when it is added to a polysaccharide or biodegradable polymer? If so then what is the mechanism ?

Similar to hydrogels which absorb water, I wonder if PGA, PLLA, and PLGA absorb any types of organic or inorganic liquid without being dissolved.

Thank you in advance for your help.

Is there any application for both hyaluronic acid and bioplastics(PHA/PHB) that join them together ?

Can be any product but the result must be a soft polymer, like a market bag

Is there any non toxic electroactive biodegradable polymer or oligomer beside aniline oligomers? specifically for tissue engineering

Hi.

In my team, I'm now responsible for synthesizing a strong anionic-exchange material, which involves the task of attaching tertiary amine functional group on a poly(vinylbenzylcholride-co-divinylbenzene) base, using triethylamine (TEA) in varied volume of toluene.

I'm having trouble with the washing step, which would remove the residual TEA. I tried using HCl 2% (v/v) in acetone, but I could not control the formation of the resulting ammonium salt, which would precipitate and deposit on my synthesized material.

Please suggest me any other appropriate cleaning method. Furthermore, I'd like to ask a detection method for residual TEA, since I don't know whether scanning for its absorption peak in the 210-220 nm region is the correct way or not.

Many thanks in advance.

I can make it clearer if the descriptions are not detailed enough, so please don't hesitate to pop in your questions.

We want to obtain biomaterial scaffold using 3D printer laser, but it have to be biodegradable polymer.

Most of the naturally available biodegradable materials such as agarose, chitin, chitosan, collagen, hyaluronan, gelatin etc. have already been explored. What else can I try? How about pectin?

Need gift sample for PLGA for research purpose

Please let me know some tests (or standards) followed to determine the biodegradability of biodegradable polymer composites.

Is there any technique which allow to somehow quantify (even if only qualitatively) the anticorrosion efficacy of polymeric coatings which are soluble in water?

Conventional approaches, such as electrochemical impedance spectroscopy, require that the sample is immersed in an electrolyte solution, but in this case the coating will be dissolved and the measurement is not representative of the coating performances. 

For example, I am looking for a procedure that allow to expose the coated metal in aerated acid environment and then somehow test it. 

Thank you!

We have an EDC crosslinked collagen based material and are performing a degradation assay to understand the byproducts released and quantify them. Is there an assay that exists to detect EDC in any form (residual, unreacted, partially reacted, fully reacted) as the material degrades or upon initial hydration? I understand there is a free Chlorine when EDC is unreacted that is no longer there upon successful crosslinking. Our initial thought is to focus on the presence of Chlorine as an indication of residual EDC. Any thoughts are appreciated!

I am looking for information about the processing of gluten in lab scale, in order to obtain shaped materials. I read about the possibilities of i) casting (probably preferable for me) and ii) thermoplasticizing. In the first case solvents are used to solubilize/disperse gluten, along with an acid or a base to make solubilization possible/efficient. What I am wishing are more detailed or actual lab experiences.

Thank you

Dear all,

I am looking for preparation biodegradable polymers from plant extract and I need to know any plant extract which can be used for the preparing such polymers.

We are working on development of biodegradable film for packaging. We want to develop moisture resistant biofilm with enough tensile strength presently whey protein isolate and soya protein isolate have been selected. Kindly suggest new subtance that can be used for making biofilm for packaging.

Hi

I want to know about a synthetic or natural polymer which it has a glass transition temperature below 40.

If you know any polymer, please let me know about that.

Regards

I have group 4 complexes with one ligand one metal and two iso-propoxide units. When I used these complexes for ROP (ring-opening polymerization) of rac-lactide, with some complexes Mn I achieved near like theoretical Mn and some other complexes I achieved more than theoretical Mn. Some of the cases I got less than theoretical Mn also.

So, how can I conform whether two iso-propoxide units initiated the polymerization or one iso-propoxide unit involved.

From proton NMR may be possible but this iso-propoxide unit peak is overlapped with polymer peak and some times not visible also because of high monomer ratio.

From GPC by observing Mn is it possible??

From MALDI we can get any information regarding how many active sites??

If you have any reference articles please suggest me.

Thank you in advance.

Kind regards,

Sreenath Pappuru.

To prove the bio degradation of biopolymers, what are all the best methods? what can accelerate degradation?

I have a nanoparticle solution made of a biodegradable polymer and a drug inside it. The particle size in aqueous solution is around 200nm. Can I use this solution to generate aerosols for inhalation experiments? Because the instrument that Kent Scientific has says that we can use any solution in their nebulizer and aerosolize it.

Also how much might the particle size be after nebulization? Any leads on this nanoparticle inhalation topic would be appreciated. Thanks

Please suggest, which are the thermoset bio composites for better properties which is almost equal to glass rein forced composites. 

Polysaccharides like dextran and sodium alginate can be dissolved in water but not in 1,1,1,3,3,3-Hexafluoro-2-propanol, which is the solvent for Polycaprolactone electrospun solution. If I still want to use PCL/HFP solution to do the electrospinning, how am I going to do with dextran and/or alginate to make sure it is in the fiber?

Thank you for advises. 

I've been preparing the ocular film (0.5 cm x 0.5 cm) of Prednisolone sodium phosphate based on polyvinyl alcohol (PVA). When I prepared the blank film using PVA, it was totally transparent with adequate mechanical strength. As soon as I added the API (7mg/film), the film had crystalline edges and it adhered to the surface tightly after drying. It was really difficult to peel the film and was too brittle. Both PVA and API are freely soluble in water; thus distilled water was used as the solvent system. The solubility of Prednisolone sodium phosphate is around 250mg/ml. When I prepared the total volume 5 ml, it had 151.2 mg of API on it. What might be the reasons for crystal formation and brittle nature of the film? I would really appreciate your answer. Thank you.

I am interested in preparing a collagen-laminin gel. When i add laminin to collagen, the strength of the scaffold become less (gel gets tearing). I need to add cells into the solution before gel formation. So i can't use any chemical cross-linkers like EDC, glutaraldehyde  (toxic to cells). 

Can you suggest me, how to prepare a collagen-laminin gel with high mechanical strength (not tearable gel)?

Thank you,

I want to prepare starch based hydrogel, which can be used as green absorbent.