Arm - Science topic

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Tetra ARMs PCR

which counsellor is better for armed forces civilian or uniformed?

Autodock vina just provides binding affinity and docked protein and ligand .when their interaction start off and view data table on biovia discovery studio,no information about inhibition constant, reference arms bond distance, intermolecular energy are found. How to find these information for autodock with vina.

In the last couple of months, a plethora of protesters were marching arm in arm in a solidarity with the people of Gaza, calling for the end of the inhumane massacre inflicted upon the people there, which shows how human beings are humanely binded together. This, of course, teased some to dehumanise these mass protesters across the streets of the West labelling them, " the Barbarians and their supporters are unfortunately inside the gates " using the exact words of Ben Shapiro who is a Jewish-American conservative talk show host. Now, engendering stereotypes about non- westerns is millennia in the making; it dates back to the twilight of Western thinking and philosophy where people outside the walls of Greece were labelled barbarian. We can find not only an echo and glimpses in the writings of Greek intellectuals, rather there's what is so orientally conspicuous to the eyes in Plato's and Aristotle's oeuvres. In fact, the very meaning of the Word " Barbarian" is used to frame people who do not speak Greek. Needless to say, that the smeary anathema was highly intensified with rise of Islam.

Return back to the coeval days, some of those protesters are calling for the end of the genocide and some are calling for a violent revolution against the colonisers ; something which was theorised by Frantz Fanon in his 1961 treatise "The Wretched of the Earth". This violent revolution will usher in the " new" who is free from the evils of the West. Decolonisation, he says, is always violent phenomenon.

"When the colonised hear a speech on western culture, they draw the machete". At any rate, Frantz Fanon called for a violent revolution outside Europe, but the existentialist Jean-Paul Sartre called for a revolution inside the gates of Europe:

"To shoot down a European is to kill two birds with one stone, doing away with oppressor and oppressed at the same time," leaving one man dead and the other is free. He dwells on "You, who are so liberal and so humane, who have such an exaggerated adoration of culture that it verges on affectation, you pretend to forget that you own colonies and that in them men are massacred in your name." Especially, if we to bear in mind that the west is dominant, hegemonic and reached what Francis Fukayama calls " The end of human history".

Nevertheless, what's so pivotally significant about these mass uprisings and the counter- discourse is that with them the people of the West are now keenly aware and acquainted with the full situation in Gaza. Thus, ushering a new era of knowledge production which is articulated by the mouths of non- Westerns: something which is framed in literary criticism as " Post-Orientalism". Under this umbrella, literary frameworks are no longer demarcated to literary texts, but in fact, are geared into other cultural discourses, inaugurating the pulverisation of literary criticism and the rise of the so-called cultural criticism!

I am doing a systematic review, and I am measuring risk of bias with RoB2 for RCT, and ROBINS-I for non RCT. My questions is, for single arm studies, can I use ROBINS-I? I am not sure how to answer the questions for the domain regarding confounding in this case.

Thank you!

Dear Colleagues

One might lose hope in a hard experience and falls in desperate. Then how can one fight desperate and be strong enough armed with hope?

Washington and NATO

Feasibility study, single centre with 3 wards. I am planning to recruit 15 nurses from the 3 wards for a three- arm parallel group design. 2 arms are intervention and one is control.

How do I assign it please?

Can I assign each ward one directly to each arm?

Or is it better to use a quasi-experimental design

I am doing a non-parametric ANCOVA (my residuals are not normally distributed and transformation did not help), I have been using the sm.ancova function from the sm package.

Now I want to do a post hoc analysis but I'm not sure how to go about it as I need a non-parametric post hoc test on the adjusted means. however, I have not found a way that works for me.

In my study, we have three arms, and I'm actually only interested in the comparison between the control and each of the experimental arms but not the experimental arms to each other, so doing a Dunnett's test but I could not find a non-parametric alternative.

I also considered a Dunns test and simply compared all three but I am not sure how to include my covariate here.

Any advice?

Please, I need assistance in calculating the sample size for the interventional study for three arms using G power.

Arm 1: Control group

Arm 2: Standard treatment

Arm 3: Standard plus advanced treatment.

I would be very glad if I could get a standard plan format for estimating that.

Thank for your advance assistance

Has anyone used (or attempted to use) a touch-monitor or a touch-screen-laptop for the recording of behavioral responses in an eye-tracking experiment with young children?

This would be ideal since young children cannot use a mouse or a keyboard. However, I am worried about the technical setup, e.g., the distance of the eye-tracker (50+ cm) vs the length of a child's arm (21-22 cm).

Any advice or experience is welcome! Thank you

Trop de conflit actuellement dans le mondes sans compte des guerre civiles dans plusieurs pays et des situation d'insécurités sont des signes annonciateurs de la 3ieme guerre mondiales.

Le plus difficiles des toutes ces situations sont des développement actuellement des missiles et des armes atomiques ouvrons le chants libres a des confrontations plus important entre des grandes puissances existants.

LATON comme une alliances militaires se préparer pour affronter la Russie lui une grandes puissances militaires , la Corée du nord qui ne cesse de menacer la Corée du sud , les autres pays sont déjà dans les conflits armes en intentes … Toute ceci menés le mondes dans un Kao sans doutes si les dirigent ne s'assoir pas sur une même table pour adopte d'autre mesure sur la paix

In the precursor miRNA stem loop structure, the 5p strand is present in the forward (5'-3') position and 3p strand (which will be almost complimentary to the 5p strand) is located in the reverse position. 5p means the microRNA is from the 5 prime arm of the hairpin and 3p means 3 prime end.

Hello! I conducted a study where I analyzed the complexity (fractal dimension) and local dynamic stability (largest Lyapunov exponent) of four muscles in both elite and sub-elite wrestlers while they performed arm drag, snap down, and double leg attack techniques. Apart from comparing each muscle between the two groups, I would like to know if there is a new method that can help me identify a pattern between the muscles involved in each technique, as well as each muscle's Lyapunov variables and fractal dimensions. I would then like to compare these patterns between the two groups.

Hello dear colleagues,

I am looking for a elastic actuator for a robotic arm. It should be able to contribute 1/3rd in lifting the arm with the motor as the motor contributes 2/3rd. It should also ensure safe landing of the arm instead of free fall and also during emergency situations like, if the motor's program is bugged and it actuates in the wrong direction then also the actuator should ensure safe landing. My intial ideas were a spring and damper syste, torsional spring alone but there are some restrictions with them so, please suggest something.

I want to know the reference value/cut off of sitting height, leg length and arm span of Indian Taekwondo player

Text books will tell you that your latisimus dorsi adducts the arm. But if the Lats are soft and squished due to the position of the arm, tensing the Lats will cause abduction from about the 6 o'clock to 5 o'clock position.

I recently read an article in the journal of bodywork in which they reviewed the literature analysing forces across joints and felt the numbers didn't add up. They concluded that the fascia was transferring force across the whole body. Could this be the missing force they didn't account for?

Hello.

I intend to insert a 20kb gene cassette into human genome using the CRISPR-Cas9 approach coupled with homology arm directed repair. It is know that this approach is less efficient due to the rare event of homology arm repairs, but it yields specific insertion at targeted loci. With such large construct, the probability in obtaining a clone will be extremely challenging.

I am seeking for advice and suggestions from anyone who has experience performing knock-in with such large construct, and which strategy was used specifically on human embryonic stem cell line.

Thank you.

What is the reason for adding an intron between homologous arms in the donor vector designed by crispr/cas9 gene editing knockout experiment? Why put the puro gene in the intron?

I have a donor template with left and right homology arms (each 1000bp long) designed for a specific sgRNA cutting site but now I want to use another sgRNA cutting 15 bp downstream of the original cutting site. Could I still use the same homology arms with the new cutting site ?

I have a donor template with left and right homology arms (each 130bp long) designed for a specific sgRNA cutting site but now I want to use another sgRNA cutting 15 bp downstream of the original cutting site. Could I still use the same homology arms with the new cutting site?

In doing a meta-analysis using articles done with time-to-event analysis, I faced the problem that some authors reported the effect size (incidence density) with person-year observations, while others reported person-month observations. Some also reported the incidence density for only the exposed group (single arm). Others reported the rate ratio (the ratio of IR in the exposed group to IR in the unexposed group).

Are there real-time applications with the ARM processor and the Scanner Server.

Is it possible to use In-Circuit Emulation of ARM processor to replicate the Matlab model. Is there any software to put the code into ARM chip? Please suggest on this.

How to calculate sample size for multi-arm (three arm) RCT?

1. The elastic column has the ability to move elastically in the earthquake as it also has the necessary plasticity for inelastic displacements. On the other hand, it does not put down large torques at the base However, the column does not have dynamics like a rigid reinforced wall, and it does not have a second lever arm in width, which reduces the overturning moment. The wall has great dynamics towards the earthquake, it has a second lever arm in width that reduces the overturning moment, but it does not have great plasticity and on the other hand, it lowers large moments to the base due to stiffness and breaks beams and joists. Also, due to greater mass, the inertia of the structure increases and thus the seismic loads. Question Is there a vertical load-bearing element that has a double lever arm, ductility, elasticity, dynamics, and does not transmit its moment to the beams and joists, and is strong towards the intersection of the base, and economical with the minimum steel reinforcement? Yes there is. But they don't use it It is called an elongated wall with prestressed and ground-consolidated ends.

2. If we want to increase the response of the structure to the earthquake, we increase the mass of the concrete by building walls and large beams. We are still increasing the steel reinforcement. Nicely we built a dynamic rigid structure something like a reinforced concrete precast which has great dynamics. Normally it should withstand the earthquake. However, it does not last, especially when the construction is tall. The reasons are as follows. By increasing the mass, we also increase the inertia of the structure and thus the seismic loads. By increasing the height and stiffness we increase the overturning moment These three factors, if they do not overturn the structure, will at least create a small overturning - swelling in the area of the base of the building. The structure losing partial soil support will divert the now unsupported static loads to the beam cross-sections and break them. This happens when we increase the dimensions of the load-bearing organism to increase the dynamic response of the structure. Question There is a solution? Yes, there is a solution. We must increase the dynamics of the structure without increasing its mass, which causes greater inertia. That is, we can increase the linear and transverse reinforcement, and the quality of the concrete, as well as reduce the diameter (not the kilograms) of the reinforcement, in order to achieve greater resistance, in terms of the shear failure of the coating concrete, due to its super strength steel in tension. This they do today and have greatly improved the dynamics and ductility, but greatly increased the cost of steel reinforcement. A steel of diameter Φ/50 has the ability to lift a two-story building with an area of 100 m2 weighing 140 tons, and today they put 8500 kg of steel on the two-story and we have failures in large earthquakes. And this is because the concrete cannot hold the steel reinforcement in it to cooperate and it breaks. Is there another solution? Yes, there is another solution and it is the one I propose. This solution removes 80% of the reinforcement so the construction becomes more economical. This solution triples the dynamic response of the structure to seismic displacements, without increasing the mass, i.e. the inertia that causes the seismic loads, and this happens because the force that counteracts the earthquake comes from an external factor, that of the ground, so it has no mass added to the structure. This solution diverts the seismic loads outside the structure and the structure is not stressed by the earthquake. This solution is called an elongated wall with prestressed and soil-consolidated ends.

A PIC microcontroller-based Robotic Arm is a project that involves the design and construction of a robotic arm that is controlled using a PIC microcontroller. The goal of the project is to create a robotic arm that can perform a range of tasks, such as picking and placing objects, manipulating tools, and executing pre-programmed sequences. The robotic arm is typically made up of several servo motors, which are used to control the movement of the arm's joints. The PIC microcontroller is responsible for receiving commands from the user, processing these commands, and sending the appropriate signals to the servo motors to control the movement of the arm. The primary aim is to manually control the servo motors and in later stages include the use of control algorithms, such as inverse kinematics, to determine the optimal path of the arm for a given task.

Arms exports to Ukraine have been controversial, supporters argue that Ukraine has the right to defend itself against Russian aggression. However, opponents argue that the arms exports could escalate the conflict and lead to further bloodshed. What is the role of western arms exporting countries in Russia-Ukraine war?

I am researching on the question do arms race lead to war? in concern with the 1965 war between india and pakistan.

Hello Researchers, Greetings of the day.

Currently, i am working on a research project on AI Robot arm using haptics approach.

for that i need 3 fingers Barrot gripper, If Any body knows about the suppliers , please ping me.

Thanks in advance.

Chromosome/DNA/Molecular Biology

Hi all, I have a question along on a similar topic if anyone could help me.

I am writing a research proposal looking at medication review in primary care incorporating an ACB calculation. I will measure ACB scores in patients before and after the medication review. I also have a control of a medication review with no ACB calculation and I will measure the ACB scores before and after review in these patients as well.

I want to use a statistical test first to calculate if there is a statistically significant reduction in ACB in the treatment and then the control arm. I then want to compare both to see if the treatment arm is better than the control arm.

I am thinking of using the Wilcoxon Signed Rank Test and the Z test for two samples. Does this make sense?

Thank in advance,

Ieuan

Hi Sir/Mam,

What statistical analysis can be applied to a randomised clinical trial with 4 intervention arms ? I have collected data for baseline, 4 weeks and 8 weeks respectively for four different types of intervention on symptoms of a psychiatric disorder pre and post-intervention. I am looking to analyse data using a t-test, Intention to treat analysis etc. Kindly suggest other statistical techniques. Out of the 4 parallel groups, the first one is a medicine group(treatment as usual) and the other 3 are new interventions( Interven A, Intervention B, Intervention A+B). i shall highly appreciate your comments and suggestions. Regards, Devendra

Hi,

I am conducting a meta-analysis with just RCTs and I am interested in the changes between baseline and outcome assessments as a response to an intervention for two study arms.

For the most of my studies, I have just mean and SD values and nothing else. So, I am not able to calculate the correlation and then find the SD value of the changes. And, I could not find any thing about how I can find the SD of the changes using the mean and SD data of baseline and outcome assessment. There is a formula on the Cochrane handbook to combine the two subgroups SD to find a common one, that you can see in on the attachment. However, I am not so sure if this is a reasonable way to calculate the SD for the changes using this formula. If you have any information about that and inform me or suggest another way to solve my problem, I will be so pleased.

Kind Regards

I'm trying to do a large knock in, and am concerned that the size of insert is too big for my method of trasfection. I found this, https://link.springer.com/content/pdf/10.1007/s13238-021-00838-7.pdf review which indicates that dsDNA donors can insert up to 7,100 bp donors but my insert may be larger than that. However, my insert also needs at least 600 bp HA, and I've been including the homology arms in the calculation for the size of donor DNA insert, and I just realized that the HA arms aren't technically inserted so IDK if maybe my total donor insert size might be smaller than I thought.

I have found this Staurastrum species in a reservoir in Costa Rica. The variation goes from cells with three arms on both hemicells, four single arms, and four double arms in either both or one of the hemicells. I wonder whether this variation could be the result of some kind of water pollution. I appreciate any thoughts about this case.

I am writing a systematic review and a fourth of the studies I found related to my topic are single-arm nonrandomized clinical trials. I applied the New Castle Ottowa Scale to them and all studies failed to meet the 70% cut-off. What is the best way to go about this? Or is it better to avoid including such studies in the review because they may be considered low-quality?

Regards,

Researcher

Hi, I would like to calculate the sample size for a 3 armed randomised control trial to study the effect of a particular intervention in a clinical population. The primary outcome is a continuous variable and the effect size is of 0.34 (obtained froma recent meta-analysis). I will have pre- and post- measures for participants in each of the three study arms. Could someone kindly guide me with this sample size calculation please?

I am trying to design a plasmid for a knock in experiment and wanted to clarify some technical issues.

I wanted to know exactly which components must be included in the plasmid.

I know that I have to include the 5' homology arm , insertion gene sequence, marker sequence and 3' homology arm.

But, I would like to know for certain the following details:

1) Should I take the whole sequence of the gene or do I need to remove the introns/UTR regions or any other unnecessary part of the sequence?

2) Which sequence should I choose for gene insertion , gene sequence or mRNA transcript sequence?

3) When designing plasmids, should I insert extra promoters and/or terminators with the insertion genes?

Hi, I did a Y-maze and I recorded the entry of each arm visually. Is there a program or website that I can use to count alternations? I have always done by hand, is very tiring.

Best,

I need to feed both arms of spiral antenna with one positive side so that I donot have 180 deg polarization in another arm of spiral. Could I get any suggestions how can I do that please?

Thank you

left side support is hinge and right side support is roller and EDCFG IS ARM

The painter Giovanni Filocamo, known as Vanni, was born in 1937 in Reggio Calabria. He attends the art school directed by Alfonso Frangipane and devotes himself to teaching "ornate" and "drawn figure". Then he moves to the Aeolian Islands, finally arrives in Frosinone, where he taught at the Bragaglia artistic high school. Multifaceted artist lived in the winter months in his home-studio in Frosinone, while in the summer he worked in Pentedattilo in Calabria, where he died in 2016. In 1992 he completed a manuscript in which collected drawings and notes on the feudal coats of arms of Pentedattilo and Melito, described the massacre of Pentedattilo, the coat of arms of the Montebello Abenavoli. Autobiographical writings are reported in the work.The copy was dedicated by the painter to Italo Biddittu who decided to make it public as a fair homage to the artist.

I want to use power-pc architecture for various performance analysis. As Gem5 doesn't contain the power-pc architecture can I design and integrate the architecture in GEM5 library?

If yes is there any documentation available for the reference to add the architecture?

Hi all, my current thoughts include

Is there a method (of using any of the above) to understand the non-linearities that might be expected in a human ligament?

Please can I get any other suggestions you might have or comments on the above?

Many thanks,

Alex

Which one is more effective when we use Mach–Zehnder interferometer as a modulator-

1) overlap the two arms in the end of the source.

2) split them as we do in the Y-branch waveguide.

I have single arm study and these results, I dont know how to explain it. What does it mean in this case censored patients, what does it mean if Ihave not estimable results NE?

How you please interpret results?

K-M (kaplan mayer) estimation of PFS

number of events n,% 10, (65%)

progressive disease n,% 8 (50%)

death n,% 5 (35%)

median 95%, CI months 4 (2,5-10) or 5 (8,6-NE)

Can one help me regarding explaining open arm initial heading errors in EPM and its relation to anxiety?

Is there is a relation between increasing neurogenesis and EPM?

I mean if stress increased neurogenesis, open arm entries would increase in stressed group?

Can anxiety increase open arm time, open arm initial heading, open arm head dipping number and central zone time in the elevated plus maze?

A flexible beam has vibration, we want to eliminate its vibration using an active arm jointed to free end of the flexible beam.

We want to build a reach task with as few elements as possible...

We have a nice workshop and also a 3D printer

I found a systematic review that based it's results on randomised, single study arm and non randomised studies. I'm considering a systematic review on the same topic however I'm concerned if the limitation mentioned above is enough to justify a systematic review in the same year.

I would like to receive suggestions about which indicators can better represent the recognition that non-state armed groups can receive from the international community.

I have been tasked with designing a 4 (maybe 5) degree of freedom of freedom robotic arm that will be installed in the back of a van. Being in a van, its of importance for it to be as lightweight as possible while drawing as little energy as possible. Does anyone have any experience with this and can pass some ideas? Any sources for designs maybe?

Is there a definitive way to determine the delay between the fundamental (800 nm) and it's second harmonic (400 nm) generated by a type 1 BBO?

Our Ti-Sapphire laser generates 800 nm pulses at 30 fs, a Mach–Zehnder interferometer is constructed. One arm is made to pass through a type 1 beta-BBO of 100 microns, while the other is not disturbed. The delay between 800 and 800 nm was determined quite easily before the type-1 BBO was placed, but a delay is introduced between the 800 and 400 nm pulses in one arm due to the type-1 BBO. Is there any way to determine the delay between them?

PS: The THG generation method was not advisable since control of individual intensities was not guaranteed in the said method.

Dear academicians/researchers , I am trying to simulate a sinusoidal wave for my robot arm. The problem is when I set the starting angle in State Target>Position and update my model it looks fine , but when I try to connect a sine wave in order to control the joint movement, I noticed that the arm is no longer started from the angle I have set recently.

Any advice will be highly appreciated.

Farah

Assume that you have a red liquid which is absorbing green light. If you put it in one arm of a Michelson interferometer and if you gradually increase the concentration of the absorbing dye, what happens to the interference fringes. In the other words what happens to the refractive index of the medium. The intensity of the fringes certainly will be reduced. it might be helpful to use a non equal beam splitter.

Mass (kg) X acceleration = Inertia which is the same as the intersection of the base. The product of inertia if we multiply it by the height we find the overturning moment of the column. If we have a wall that has a double lever arm (except for the lever arm of height and that of width) then the product of the tipping moment is divided by the width of the wall and this will be the tipping moment of the wall. If the wall is anchored at its base, a reaction will be created to the overturning torque of the lever, which multiplies (as we have seen) the overturning forces, since, as the height increases, its overturning force also multiplies. If the anchor is at the bottom of the wall, the critical failure area will also appear there and the anchor point is also the lever of the wall. Question If the anchoring of the wall is not at its lower ends, but is at its upper ends. That is, if we place this wall on a machine - press and apply pressure to it, it will remain a lever arm or its mechanical condition will change; 1) Will we have a multiplication of the tipping forces as it happens when the anchor is applied to its lower extremities? 2) Will a critical area of ​​failure of right forces N (compression and tension) be created as it happens when the anchorage is applied to its lower extremities? In short, we know that the walls drop high torques at the base since that is where the reaction of any substandard anchorage is. If the anchoring is done on the roof (ie if pre-tensioning is applied between the upper ends of the sides of the wall and the foundation ground) it will lower torques at the base and will create or not a critical failure area;

I did try modified Newcastle Ottawa scale but after removing the comparability of cohorts options, I can score out of 6 only in which most articles are getting only 4 or 5 which is not considered good as you all know. So is there any other tool that I can use or there is no need to do quality assessment in single-arm studies?

Why we do not consider the potential and kinetic energy of the motor at the joints in the two arm robot..I see only considered the links in the Lagrange equation .However the motor at the joint has height same as link has height this mean has potential energy also when the first link rotate the body of the motor will rotate to gather with second link which produce kinetic energy

I tried performing a meta-analysis of single arm studies (i.e without controls) using openMeta-analyst which allowed me to combine the effect estimate in form of proportions. Different organ transplants with similar endpoint were included from various studies. I was able to obtain

1) the overall estimate of all organs

2) perform sub-group analysis to find the estimate for specific organs, timing of treatment(<7days and >7 days), study design and availability of insurance cover or not

3) Did meta-regression to assess impact of covariates like timing of treatment

My PI wants a direct comparison of the point estimates from the subgroups already meta-analyzed. Is this a good practice and how can I do this without controls? I thought of using one organ say heart as the intervention and liver as control and then including by the number of events/total number of subjects for studies that provided data. For the corresponding control or intervention without values (since this direct comparison was not done in individual studies), I used zero and then corrected with 0.5 automatically which the software handles pretty well. Is this an ideal way to go in order to obtain the RR or OR across different sub-groups?

Please see below a schema of what I did:

Study organ 1 organ 2

A 0/0 6/20

B 0/0 4/9

C 0/0 8/23

D 6/21 0/0

E 34/45 0/0

F 12/50 0/0

ABC don't have information on organ 1 while DEF don't have info on organ 2. I am hoping this set up can help me unravel the difference between organs for a specific outcome measured.

I would appreciate your urgent response.

Hi, May i know how to perform meta analysis for single arm observation studies (i.e., contains one group, either control or intervention)?

I have datas of mean, sample size and SD for all studies and would like to perform meta analysis.

Which softwares should I need to use for Single observation ?

How to deal with missing datas in the studies? I am not too sure if we can ignore the missing datas without any rational?

Thanks

I'm working on a way to give predict/generate a set of possibly associated skills for a given skill/technology. I've done some research and I've found that ARM algorithms are the closest thing to a solution for my problem. My question is how can I exploit the results of Apriori algorithm in order to predict the set of skills associated to a possible input (one skill)? Is there a better way than this approach?

Much thanks.

Greetings.

I have been trying to fabricate a Hall bar on a SiGe/Ge heterostructure for transport measurements and so far my devices have failed to show ohmic behaviour at low temperatures. I have troubleshot several possible issues, from the cleaning process of native oxide before the ohmic metal deposition to the annealing of the ohmic contacts. Now, the last issue I have stumbled upon is the geometry of my devices. I have found the information in the picture attached to this message. I have deposited my ohmic metal all along the Hall bar arms, making it more like the top figure. I imagine this is a mistake as it seems to increase the error.

My question is, why is this important? Why the relative dimensions of the Hall bar arms are important and how they influence measurement? Also, why shouldn't the contacts be close to the main channel like in the top figure?

A colleague of mine has successfully fabricated a Hall bar and by checking his design, the difference with mine are a very large area for the ohmic contacts and the deposition of ohmic metals at the "tip" of the arm. This is why I am wondering how the position of the ohmic contacts affects the measurement.

Thank you very much.

Best regards,

Gabriel.

Hello, I had done my experiment which observing ARM lipase in SDS gel and this experiment related to affinity chromatography. But I sadly get 3 bands at the well that I insert the elution solution. It supposed to appear only one band which referring to ARM Lipase only. What does that mean? and Is there any precaution step or solution to prevent this occur?

According to the literature published by

Md Sahrom Abu, Siti Rahayu Selamat, Robiah Yusof and Aswami Ariffin

Formulation of Association Rule Mining (ARM) for an Effective Cyber Attack Attribution in Cyber Threat Intelligence (CTI) was recommended as a good approach

It has been observed that a single arm study is designed to validate a pharmacopoeial formulation for its effectiveness. As such there is no guideline available in India for acceptance of the level of evidence required to support validation of a traditional medicinal product.

Utilizing REDCap, we will be enrolling patients in a clinical trial where we need them to:

- undergo a treatment or placebo

- complete a 2 wk f/u questionnaire in the office

- complete a 6 wk f/u questionnaire in the office

They may be at 3 different offices for their appointments when they complete it. We are planning to use an iPad. How can we have it fire the surveys, link to their enrollment data or arm of their trial without using emails or QRS codes?

In one of the articles, I read the following hypothesis:

Regarding ARM processors, I wonder if the Program Counter Register (PC) is a part of the processor’s control logic or not.

I have used 1ml HF +199ml water to etch it but was getting a cellular structure. I really do hope I get a suggestion to get the SDAS and the intermetallic sizes if anyone has work on it before..

Hello, anyone out there familiar with Trial Sequential Analysis (TSA) software developed by Copenhagen Trial Unit? The free software is available at: http://www.ctu.dk/tsa/downloads.aspx Manual is available here: http://www.ctu.dk/tsa/files/tsa_manual.pdf

Summary of my questions up here: 1. How do you obtain required information size (RIS) by using traditional 5% significance boundary, 'cause for what I'm aware of, RIS can only be calculated by α-spending boundary using O'Brien-Fleming method? 2. Where and how can I set "δ" value while applying α-spending boundary ?

----------------------------------------------------------------------------------------------------------------------------------------- So I've been working on a project involving meta-analysis and trial sequential anaylsis of noninferiority randomized control trials (RCTs). I've met some technical problems which I can't solve, so I tried to look for literature of similar study design and luckily I found this study entitled Haloperidol Versus 5-HT 3 Receptor Antagonists for Postoperative Vomiting and QTc Prolongation: A Noninferiority Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials.

Regarding the setting of conventional 5% significance boundary and alpha-spending boundary using O'Brien Fleming method, here I quote " The first was the classical boundary, setting the α error to 5%. The required estimated information size was 799, and our cumulative value was found to be 859. Further, we used the O'Brien-Fleming α-spending function for testing for futility. For this the δ was set at 10% and β at 20%. The TSA graph clearly showed that cumulative Z scores were well past the inner wedge of futility and fell within the range of actual equivalence. The information size of 859 was well past the required 812 for this method as well" Obviously, the equivalence of haloperidol and 5-HT 3 receptor antagonists is proved.

I tried to simulate and run the software myself using exactly the same data provided in this article, as shown in Forest plot. After adding every single trials with the events/total, I started to set up the parameter needed for applying both conventional 5% significance boundary and α-spending boundary. The parameters needed for setting up the traditional 5% significance boundary are type I error (5%) and boundary type (two-sided) as shown in figure 1. As you can see, there's no where showing the estimated RIS, which gave rise to the first question I mentioned above. Next, I filled in parameters needed to set up α-spending boundary, including α=5%, power=80%, information axis=sample size, information size=estimate, incidence in intervention arm=85/428=19.9, incidence in control arm=91/431=21.1, heterogeneity correction=model variance based, as shown in figure 2. However, there's nowhere for me to put in "δ" value, which was mentioned and set 10% in the study mentioned above. With my setting, the estimated RIS is 35533, far larger than 812 as mentioned in the article, and wasn't able to perform TSA due to too little information used, as shown in figure 3.

So my question is obvious, how did they obtain such results (please refer to TSA.jpg) ?????? Where did I do incorrectly ?

Thank you for your time going through this and it'd be nice to give me some help !!!