Analytical Chemistry - Science method

In this paper, a TDINA model is proposed to enhance the effectiveness of analytical chemistry teaching in colleges and universities by combining the cognitive ability level, personalized learning needs, knowledge mastery and other personality characteristics of student users. Firstly, it introduces the existing common models for cognitive diagnosis...

Green analytical chemistry represents a transformative approach to analytical science, emphasizing sustainability and environmental stewardship while maintaining high standards of accuracy and precision. This review highlights recent innovations in green analytical chemistry, including the use of green solvents, such as water, supercritical carbon...

RESUMEN: Los programas de evaluación externa de la calidad constituyen una herramienta práctica y útil para la evaluación del desempeño de los laboratorios clínicos en las determinaciones de rutina, hormonales o de marcadores tumorales, entre otros. El objetivo fue evaluar el desempeño de laboratorios clínicos privados de varios estados del país en...

Natural enzymes, despite their superior catalytic proficiency, are frequently constrained by their environmental sensitivity and the intricacies associated with their extraction and preservation. Consequently, there has been a significant impetus in the scientific community to develop robust, economical, and accessible enzyme mimics. In this contex...

Polymer inclusion membranes (PIMs) have been reported to be useful for the selective separation of numerous metal ions, with multiple applications in areas such as analytical chemistry, water quality monitoring, water treatment, and metal recovery. This review aims to update the recent advancements related to PIM technology in metal ion separation,...

Integral membrane proteins (IMPs) are pivotal for cellular functions but challenging to investigate. Here, IC‐FPOMP (in‐cell fast photochemical oxidation of MPs) is introduced, a method enabling in situ footprinting of IMPs within live cells. IC‐FPOMP generates reactive oxygen radicals from various precursors (TiO2 nanoparticles or H2O2) near the m...

Most research studies aim to reach new methods in diagnosis, whether for diseases or materials used in various fields of science such as medicine, physics, agriculture, etc., which help in early detection of most difficulties, whether a disease or a material used to solve a specific problem. One of the techniques used for such purposes is ultraviol...

In this study, the “Ethanol as an Internal Standard” method was employed for the quantification of volatile congeners in wines using headspace solid phase microextraction (SPME) as a way of sampling and gas chromatography coupled to mass spectrometry detector (GC–MS) for detection. The “Ethanol as an Internal Standard” method is fast, cheap, and si...

UNDERSTANDING QUALITATIVE ANALYTICAL CHEMISTRY: THE DEVELOPMENT OF POPULAR SCIENCE TEXTS IN PRACTICAL CLASSES. One of the best ways to consolidate the experimentation seen in practical Analytical Chemistry classes is to demonstrate to students how the knowledge contained in such discipline is present in everyday situations. Science communication is...

Surface-enhanced Raman spectroscopy (SERS) technology, possessing extraordinary sensitivity and an outstanding ability to furnish molecular-level information, has emerged as a revolutionary technique within the domain of analytical chemistry. This review comprehensively and in-depthly investigates the application of SERS in the field of pharmaceuti...

Understanding the nutritional profile of fish species found in this river is crucial for sustainable fisheries management and ensuring the provision of healthy, high-quality protein sources for the population. Spatio-temporal assessment of proximate composition of tilapia (Oreochromis niloticus) and Silver catfish (Chrysichthys nigrodigitatus), Tom...

The acquisition of kinetic data in QD-based PL sensing methodologies has been revealed to be an auspicious alternative in applying these nanomaterials in analytical chemistry, enabling enhanced discrimination and quantification of analytes, even in complex sample matrices. The accessibility of kinetic measurements, which use routine laboratory inst...

Irinotecan (IRNO) is used as a first line anticancer drug for the treatment of mainly metastatic colorectal cancer. Globally, cancer is sorted as the second cause of death. It is important to analyze anticancer drugs carefully and rapidly in different pharmaceutical formulations. The purpose of our work was to develop and validate green, simple, co...

GLANCE (Graphical Layout Tool for Analytical Chemistry Evaluation) is an innovative and adaptable free, editable template specifically designed to help researchers visually summarize their analytical chemistry methods in a structured and clear manner. It provides an accessible solution to the challenge of presenting complex scientific data, offerin...

Microextraction techniques, such as electromembrane extraction (EME), have greatly advanced analytical chemistry by providing efficient, cost-effective, and eco-friendly sample preparation methods. EME is especially promising for ionizable analytes, with its success relying on optimizing multiple experimental variables. Traditionally, optimization...

UV-Vis spectroscopy is a workhorse in analytical chemistry that finds application in life science, organic synthesis and energy technologies like photocatalysis. In its traditional implementation with cuvettes, it requires sample volumes in the milliliter range. Here, we show how Nanofluidic Scattering Spectroscopy, NSS, which measures visible ligh...

Biological nanopores have become powerful tools for single-molecule analysis in many fields, including metal ion detection, single-molecule chemistry, polymer size discrimination, nucleic acid sequencing, and protein/peptide/glycan analysis. Among all biological nanopores, aerolysin is considered one of the most promising nanopores for analytical a...

The management of scientific data plays a key role in all research areas and has increased in importance. Providing researchers with customizable data management tools is crucial for effectively managing data according to the FAIR principles. These principles have been defined by Wilkinson et al. in 2016, which describe how scientific data should b...

In this application-oriented booklet the fundamentals of UV/VIS spectrophotometry are first explained before focussing on its main use in analytical chemistry, and in particular on the applications in the life sciences.

This study examines the degradation pathways of chiral pesticides in agricultural soils, with a focus on their stereoselective behavior and environmental fate. Specifically, it explores the degradation kinetics of the chiral herbicide profoxydim, evaluating how soil chemistry, microbial activity, and environmental conditions influence stereoisomer...

Modern society is increasingly reliant on sustainable solutions. We suggest a creative study that meets the standards of sustainability in analytical chemistry. The objective is to promote eco-friendly methods for concurrently detecting Gatifloxacin (GAT) and benzalkonium chloride (BEN) in ocular solutions. Using a sustained mobile phase flow rate...

Main conclusion Aptamer technology has significantly advanced the field of plant research, emerging as a tool for enhancing agricultural productivity, plant growth, and environmental monitoring. Abstract Aptamers are short nucleotide or amino acid sequences that can bind to a range of target molecules with high affinity and selectivity. In recent...

A miniaturised, eco-friendly and efficient multiclass method for the simultaneous determination of 87 veterinary drugs, pesticides and mycotoxin residues in beef muscle samples by ionic liquid-based dispersive liquid–liquid microextraction (IL–DLLME) and liquid chromatography tandem mass spectrometry (LC–MS/MS) was developed and validated according...

One way to combat the black pharmaceutical market is to exchange experience and knowledge among the laboratories involved in this fight. A beneficial approach is compiling application examples that demonstrate the development and growing potential of the two analytical techniques that are undoubtedly useful in investigating pharmacologically active...

A significant variable in the genesis of peptic ulcers is Helicobacter pylori, which could be eliminated through several strategies. Amid them, there is a strategy based on receptor histamine-2 (e.g., famotidine) antagonist in conjunction with metronidazole and amoxicillin as antibiotics. This research used UV spectrophotometry paired with chemomet...

Poor data quality limits the advantageous power of Machine Learning (ML) and weakens high-performing ML software systems. Nowadays, data are more prone to the risk of poor quality due to their increasing volume and complexity. Therefore, tedious and time-consuming work goes into data preparation and improvement before moving further in the ML pipel...

Poor data quality limits the advantageous power of Machine Learning (ML) and weakens high-performing ML software systems. Nowadays, data are more prone to the risk of poor quality due to their increasing volume and complexity. Therefore, tedious and time-consuming work goes into data preparation and improvement before moving further in the ML pipel...

The developed method for simultaneous detection of levodopa and carbidopa was able to separate the peaks of the drug and sodium bisulfite in the in-vitro release samples and stability samples. Levodopa (LD), a pro-drug of dopamine, is used as the gold standard treatment for Parkinson’s disease. It is usually prescribed with carbidopa (CD) to preven...

X-ray imaging is an important tool for non-destructive analysis, providing insights into internal structures without damaging the sample. Traditional X-ray techniques often require high doses of radiation and are not flexible enough, requiring advanced methods that improve resolution while minimizing exposure. This chapter examines state-of-the-art...

Optical chirality is a fundamental property of light that plays a crucial role in chiroptical spectroscopy, analytical chemistry, spin photonics, and astrobiology. However, giant optical chirality at the wavelength beyond 15 μm remains untapped, which hinders its various applications, such as ultrasensitive vibrational circular dichroism, in the mi...

A fast, reliable, and cost-effective electrochemical voltammetric sensor has been developed for the ultrasensitive detection of Meropenem (MER), a non-classical β-lactam antibiotic, for therapeutic monitoring purposes in the evolution of personalized medicine. Enhanced voltammetric response was attained at a disposable pencil graphite electrode (PG...

There have been multiple investigations into the decomposition of human remains in aqueous environments in recent history. There are multiple factors that are important in the rate of decomposition in any environment, however there are certain factors that have a larger effect in aquatic environments. Temperature, salinity and pH are some of the fa...

Anthropogenic evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are currently built from six different nucleotides. Thus, six-lett...

Mn metal has become a highly promising candidate anode of aqueous batteries due to its high abundance, non‐toxicity, relatively low redox potential, and large theoretical capacity. However, the development of Mn ion batteries (MIBs) is hindered by controversies over reaction mechanisms, metal hydrogen evolution reactions, and poor conversion effici...

: 2-Hydroxy-1,4-naphthoquinone, widely recognized as lawsone, is a natural dye obtained from the henna plant (Lawsonia inermis), known for its biological activity and diverse applications in biochemistry and analytical chemistry....

Rivaroxaban, a direct factor Xa inhibitor anticoagulant, requires precise and reliable analytical methods for its quantification in pharmaceutical and biological matrices. This work presents the evolution of analytical techniques developed between 2013 and 2024 for rivaroxaban determination. UV spectrophotometric methods offer simplicity and cost-e...

Diabetes mellitus is major chronic disease found in human due to stressful lifestyle and bad food habit. Recently, the Central Drugs Standard Control Organization of India has approved combination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohydrate for the management of diabetes mellitus. Numerous chromatographic meth...

Continuando con la nostra escursione nella storia della chimica analitica delle sostanze grasse non possiamo non parlare di questo fondamentale lavoro, pubblicato in due diverse note nell'anno 1959. La prima parte, quella che andremo ad analizzare in dettaglio, descrive le conoscenze fondamentali che stanno alla base della analisi spettrofotometric...

Surface‐enhanced Raman spectroscopy (SERS) is a key technique in analytical chemistry because of its exceptional sensitivity and specificity for detecting a broad spectrum of substances. Herein, a silicon (Si) substrate fabricated using vortex femtosecond laser beams in ambient air is proposed as an innovative, highly sensitive, and reusable platfo...

RNA‐cleaving DNAzymes are in vitro selected functional nucleic acids with inherent catalytic activities. Due to their unique properties, such as high specificity, substrate cleavage capability, and programmability, DNAzymes have emerged as powerful tools in the fields of analytical chemistry, chemical biology, and biomedicine. Nevertheless, the bio...

The proximate and mineral composition of cocoyam (colocasiaescienta) grown in Bauchi, Plateau, Gombeand Kaduna States were analyzed using association of official analytical chemistry. The analysis included, ash; 3%, 2.6% and 3.2% crude protein; 2.7%, 3.4%, 2.8% and 2.9% crude fibre; 1.5%, 1.9%, 1.8% and 1.0% crude fat; 0.3%, 0.3%, 0.2% and 0...

Experimental designs are essential mathematical tools in fields like agronomy, chemistry, and analytical chemistry for optimizing processes and minimizing variations. Doehlert designs, in particular, are valued for their efficiency in exploring experimental space with minimal experiments, providing detailed insights into complex processes. In analy...

Este trabalho apresenta um relato de prática educativa referente a uma proposta de ensino para a Prática como Componente Curricular desenvolvida no contexto da disciplina Química Analítica Qualitativa, do curso Licenciatura em Química de uma instituição pública federal do estado de São Paulo. Tendo como base a metodologia da pesquisa-ação, um conju...

Recent years have witnessed tremendous advances in wearable sensors, which play an essential role in personalized healthcare for their ability for real-time sensing and detection of human health information. Nanozymes, capable of mimicking the functions of natural enzymes and addressing their limitations, possess unique advantages such as structura...

Developing methods for the analysis of hazardous chemicals and complex parenteral formulations is a challenging process. To address these challenges, the integration of green chemistry principles and design of experiments proves highly effective. This study introduces a novel approach that combines green analytical chemistry and design of experimen...

Background:Gas chromatography (GC) remains a cornerstone in analytical chemistry, extensivelyemployed for the detection and quantification of process impurities, including volatile organic compounds (VOCs) and genotoxic impurities (GTIs) in pharmaceutical and industrial applications. Main Body:This review examines the evolution of conventional GC t...

This review highlights recent advancements in analytical techniques used for the determination of Vitamin B2 (riboflavin) in pharmaceuticals, foods, and biological samples. Various methods, including UV-Vis. spectrometry, fluorimetry, chromatography, mass spectrometry, and electrochemical techniques, are discussed. These methods leverage the unique...

Este artículo explica el proceso de diseño, construcción y evaluación del Metrostat, un potenciostato de bajo costo con Arduino para estudios electroquímicos. Para evaluar la relación costo-eficiencia, el Metrostat se comparó con un dispositivo comercial y con los dispositivos elaborados en otras investigaciones. También se realizaron experimentos...

The study of green analytical chemistry has garnered significant attention in the context of mitigating global environmental contamination. In this study, we present two methodologies for environmentally friendly chromatography that enable simultaneous and specific determination of Saxagliptin (SAX), metformin (MET), and a pharmacopoeial impurity o...

Not only do surface-growing microbes such as biofilms display specific traits compared to planktonic cells, but also they display many heterogeneous behaviors over many spatial and temporal contexts. While the application of molecular genetics tools to extract or visualize gene expression or regulatory function data is now common in studying surfac...

Aminopolyphosphonates (APPs) are widely used as chelating agents, and their increasing release into the environment has raised concerns due to their transformation into aminomethylphosphonic acid (AMPA) and glyphosate, compounds of controversial environmental impact. This transformation highlights the urgent need for detailed studies under controll...

Automation of laboratory processes is crucial in analytical chemistry, as it enhances experimental reproducibility by eliminating repetitive tasks and reducing human errors. In this context, the integration of laboratory automation techniques into chemical analysis, particularly utilizing electrochemical field-effect transistor (FET)-based sensors,...

Economically motivated adulteration threatens both consumer rights and market integrity, particularly with high-value cold-pressed oils like cactus seed oil (CO). This study proposes a machine learning model that integrates analytical measurements, data simulations, and classification techniques to detect adulteration of CO with refined sunflower o...

This research investigates the effect of integrated traditional media on using TikTok and Instagram; to increase students 'motivation and learning outcomes in qualitative analysis in the 2015-6 qualitative analysis for groups (I) and (II)) multi-representation approach and problem-based learning model (IB) level 2, 2023. In a quasi-experimental des...

A new methodology is presented for the rapid, specific, and sensitive detection of irinotecan (CPT-11), a chemotherapeutic agent utilized in the treatment of cancer, along with its metabolically active derivative, SN-38, via laser desorption/ionization mass spectrometry (LDI MS). The method includes the detection of camptothecin (CPT), which can be...

The development of motivated biosensors associated with the study of a large number of different substances is one of the most important areas of development of analytical chemistry. This goal in the development of certain biosensors was necessary for a sufficiently clear, fast, qualitative and quantitative determination of the desired component. C...

The standard addition method is widely used in analytical chemistry to compensate for matrix effects. While effective with single signals (e.g., absorbance at a single wavelength) and independent of matrix composition or blank measurements, it has limitations with high-dimensional data (e.g., full spectra). Existing methods for high-dimensional dat...

Chemometrics, which applies mathematical and statistical methods to aid in experimental design, data analysis, and process optimization, is gaining more importance. It plays an important role in enhancing the sustainability of analytical methods when integrated with green analytical chemistry. Applying chemometrics to liquid chromatographic methods...

White and Green Analytical Chemistry are innovative approaches in analytical chemistry that prioritize both sustainability and efficiency. Together, these approaches aim to advance scientific research while minimizing environmental impact and enhancing safety. This integration of environmental consciousness into analytical practices represents a si...

Fluorescence characterization of halophilic archaeal C50 carotenoid–bacterioruberin extracts was investigated using UV/Vis and steady-state fluorescence spectrophotometry in solvents with different polarity. Different extracts showed maximum absorption and fluorescence wavelengths between 369–536 nm and 540–569 nm. Stokes’ shifts varied between 50–...

Background As the common antibacterial drugs in folic acid oral liquid, parabens are listed as mandatory substances in the quality standard. Both the Chinese Pharmacopoeia and the United States Pharmacopoeia use high performance liquid chromatography for the determination of folic acid, but the quantitative methods of parabens are different. Pharma...

Background/Objectives: Janus kinase inhibitors open new horizons for small-molecule drugs in treating inflammatory bowel disease, with ritlecitinib demonstrating significant efficacy in clinical trials for ulcerative colitis and Crohn’s disease. Ritlecitinib, a second-generation JAK3 inhibitor, is a novel therapeutic agent for alopecia areata and o...

There have been multiple investigations into the decomposition of human remains in aqueous environments in recent history. There are multiple factors that are important in the rate of decomposition in any environment, however there are certain factors that have a larger effect in aquatic environments. Temperature, salinity and pH are some of the fa...

A rapid and effective analytical method was developed for the detection of triclosan in wastewater samples using a hydro-phobic deep eutectic solvent thymol-lidocaine (Thy-Lid, molar ratio of 1:1) and dispersive liquid-liquid microextraction (DLLME). The analyte was determined by high-performance liquid chromatography with a photodiode array detect...

Aloe vera, a drought-resistant succulent, is renowned for its wide-ranging medicinal properties. It has significant health benefits, including anticancer, wound and burn healing, hypoglycemic, gastroprotective, antifungal, and antiinflammatory properties. These properties have led to its use in various commercial applications, particularly in skinc...

O ensino de Química ainda é marcado pela abordagem de conteúdos informativos. Esse formato de ensino, utilizado na maioria das instituições, distorce o viés investigativo do aluno, pois deixa de contribuir para a percepção discente sobre a elaboração do conhecimento. Atualmente, novas práticas pedagógicas têm proporcionado uma maior aprendizagem ao...

A simple, rapid, and reproducible high-performance liquid chromatography (HPLC) method has been developed and validated for the determination of β-sitosterol in the pharmaceutical dosage form of moist exposed burn ointment (MEBO). This method involved an effective sample procedure for extraction of β-sitosterol from MEBO using an alkali saponificat...

This unique book covers the latest developments related to chitin, chitosan, and their derivatives. The research findings along with examples and ample references make it a very useful reference for researchers, scientists, professionals, and students engaged in academic and industrial research." Prof. Lai Chin Wei Universiti Malaya, Malaysia This...

BACKGROUND Lanthanum ions (La³⁺) are of great importance in many applications, so development of effective sorbents for selective recovery of La³⁺ is urgently required. In this work, an ion‐imprinted polymeric sorbent of La‐RSPY with secondary amine, phenolic, and pyridyl groups was synthesized through a Schiff base reaction between 4‐aminoresorcin...

Palladium and platinum are non‐endogenous precious group 10 metals that are extensively used for catalytic materials, electronics, and drugs. These heavy metals have recently gained more attention in biomedical applications and drug development. At the same time, concerns arising from metal content in various sample types have provoked chemists to...

The identification of ClO⁻ and iron ions in water medium is a difficult task and has been one of the hot issues in analytical chemistry. For this objective, we synthesized carbon nanoparticles (CNPs) through a solvothermal reaction between 1, 3, 5-trimesic acid and o-phenylenediamine, which served as a sequential fluorescent probe for ClO⁻ and Fe²⁺...

The analysis of cosmetic products represents an important field of analytical chemistry, since the demand for new formulations is continuously increasing. Regulations about prohibited/regulated compounds are applied in each country. Among the substances that are banned in cosmetics, corticosteroids represent a potential harm for consumers since the...

Machine learning with its integration into analytical chemistry, and more specifically spectrometry, is imposing new trends in data analysis and pattern recognition. On the other hand, spectral measurement is an important technique to analyze the influence of matter and electromagnetic radiation that generates complex and multidimensional data, whi...

As nanotechnology advances and gets more integrated into several scientific domains, advantages are currently achieved. This is mainly due to the unique properties of nanoparticles (NPs) and the originality they bring to these applications. Particularly analytical chemistry, environmental sciences, and medicine. Nanotechnology has become one of the...

Microplastics (MPs) are exudated fragments and fibers from environmental plastic refuse in the lower millimeter to micrometer range with some intentionally created particles and degraded exudates from anthropogenic sources. These particles are often hard to identify due to extensive weathering and material heterogeneity from additives. Leveraging t...

Tetracyclines (TCs) are widely employed for the prevention and treatment of diseases in animals besides being deployed to promote animal growth and weight gain. Such practices result in trace amounts of TCs occurrence in water and foodstuffs of animal origin, including eggs and milk, thus posing severe health risks to humans. To ensure the food and...

All these papers address different aspects of the development and application of molecularly imprinted polymers, and some of them were dedicated to the application of Molecularly Imprinted Polymers as Tools for Analytical Chemistry and/or Medical Diagnostics.

An overview of the electrochemical sensors and biosensors developed at Universidad Autónoma Metropolitana Unidad Iztapalapa, is summarized by describing the principal contributions in the field performed by the Electrochemistry and Analytical Chemistry research areas of the Chemistry Department. Here, we divided the contributions into four main gro...

Gravimetry is a simple and fast method used to determine the weight percentage of alkaloid content in natural samples when analyzing compound content. Gravimetry is a basic knowledge and skills in analytical chemistry. A student-centered learning approach is needed to acquire integrated chemical laboratory knowledge and skills. Integrated learning...