Science topics: MedicineAllergology
Science topic

Allergology - Science topic

Explore the latest publications in Allergology, and find Allergology experts.
Filters
All publications are displayed by default. Use this filter to view only publications with full-texts.
Publications related to Allergology (3,592)
Sorted by most recent
Article
Full-text available
Background One of the main barriers to vaccination against SARS-CoV-2 is the fear of developing hypersensitivity reactions to any of its components. Although these reactions are very rare, it is necessary to establish an effective protocol to detect patients at risk of developing them. The aim of this study was to evaluate hypersensitivity reaction...
Article
Full-text available
Currently, there are a few detailed guidelines on the overall management of children and adolescents with moderate-severe atopic dermatitis. AD is a complex disease presenting with different clinical phenotypes, which require an individualized and multidisciplinary approach. Therefore, appropriate interaction between primary care pediatricians, ped...
Article
Full-text available
Background The SARS-CoV-2 outbreak pushed the Italian government to start a strict lockdown, replacing school attendance with long-distance learning. This caused reduced exposure to sunlight but increased exposure to screens. Vernal keratoconjunctivitis (VKC) is a chronic inflammatory ocular condition in which exposure to light plays a cardinal rol...
Article
Full-text available
Background Guidelines recommend standard doses of antihistamines as first-line, and updosing of antihistamines as second-line treatment for the management of chronic urticaria (CU). However, remission rates with different types of first- and second-line treatments and indicators of antihistamine response are largely lacking in the literature. Obje...
Article
Full-text available
Zusammenfassung Hintergrund Obwohl allergologische Erkrankungen zu den wichtigen Gesundheitsstörungen laut ärztlicher Approbationsordnung zählen, ist die Allergologie in Deutschland nicht als selbstständiges Fach im Studium der Humanmedizin verankert. Ziel der Arbeit Da sämtliche Universitäts- und Hochschulstandorte mit dieser Herausforderung umg...
Article
Full-text available
The worldwide incidence of allergic diseases has been continuously increasing, and up to one in every five people are currently affected by these medical conditions. Although seldom fatal, allergies have a profound impact on children’s growth, development, and quality of life, besides being associated with heavy healthcare costs and resource utilis...
Article
Full-text available
The study of genes controlling cytokine activities of is among important tasks when assessing predisposition and revealing pathogenetic links of initiation and course of clinical disorders. Aberrant production of cytokines and dysregulation of immune response may be considered genetic predictors associated with differentiation and functioning of T...
Article
Full-text available
Background Allergies constitute an important public health problem, and epidemiological data is crucial to developing strategies for its prevention and therapy. Few population-based studies are available for data on allergies and sensitization. However, as these studies are expensive and time-consuming, novel approaches are searched for. Objective...
Article
Full-text available
p-Phenylenediamine (PPD) has been classified as a strong skin allergen, but when it comes to toxicological concerns, benzoquinone diamine (BQDI), the primary oxidation derivative of PPD, is frequently considered and was shown to covalently bind nucleophilic residues on model peptides. However, tests in solution are far from providing a reliable mod...
Article
Full-text available
Background: Birch pollen-related apple allergy is the most frequent IgE-mediated food allergy in Central-Northern Europe with Mal d 1 as major allergen. Its concentration in apples varies with the cultivar and storage time. Year-round appealing, hypoallergenic cultivars still are needed to satisfy the nutritional needs of affected individuals. We...
Article
Full-text available
Purpose: We have previously studied clinical and allergological aspects of sick building syndrome (SBS) cases with ocular disorders and found that SBS is suggested to be partially induced by an allergic response. We analyzed the cytokine production profiles of conjunctival and peripheral blood lymphocytes in patients with SBS with ocular manifesta...
Article
Full-text available
Aims/hypothesis Insulin allergy is a rare but significant clinical challenge. We aimed to develop a management workflow by (1) validating clinical criteria to guide diagnosis, based on a retrospective cohort, and (2) assessing the diagnostic performance of confirmatory tests, based on a case–control study. Methods In the retrospective cohort, pati...
Article
Full-text available
Introduction: Why can a peanut allergy cause exceptionally severe reactions, but not to everyone? Is there a way to identify patients who might experience these reactions? What is molecular diagnostics of allergy and what are the benefits of diagnosing patients at risk of anaphylaxis after consuming peanuts? Purpose: The aim of the study is to show...
Article
Full-text available
Background: Allergic reactions after messenger RNA (mRNA)-based COVID-19 vaccines have been reported but detailed descriptions and further actions are not well characterized. Objective: To describe the symptoms of possible allergic reactions after the mRNA COVID-19 vaccine and outcomes of further vaccination. Methods: We descriptively analyzed...
Article
Full-text available
Dear Editor, The connection between allergy and autoimmunity has been explored in different autoimmune conditions apart from celiac disease (CD). Epidemiological data on the prevalence of allergy in autoimmune diseases such as type 1 diabetes mellitus (T1D), multiple sclerosis (MS), and rheumatoid arthritis (RA) have raised the question of whether...
Article
Full-text available
The main risk factor for the development of food allergies (FAs) in children is atopic dermatitis (AD). AD is usually recognized as the Th1/Th2 paradigm of allergic disease. Recently, the Th1/Th2 paradigm in allergy and autoimmunity has been revised, including the role of the Th17 cell population and related cytokines. However, there are only a few...
Article
Full-text available
Purpose of the Study The purpose of the study is to examine country-specific important allergens, identify hidden allergens, and interpret MDA results to diagnose Type I allergic reactions. Materials and Methods Self-conducted research has been provided which was aimed at identifying allergen-specific IgE to latex in patients with allergic diseases...
Article
Full-text available
Bacterial lysates (BLs) are mixtures of bacterial antigens that have been used for many decades to minimize the risk of recurrent respiratory tract infections in both pediatric and adult populations. Research on the use of BLs is also conducted in allergology. Biomedical databases were searched for articles on the use of BLs in the treatment of all...
Article
Full-text available
Information on the allergenic pollen season provides insight on the state of the environment of a region and facilitates allergy symptom management. We present a retrospective analysis of the duration and severity of the allergenic pollen season and the role of meteorological factors in Istanbul, Turkey. Aerobiological sampling from January 2013 to...
Article
Full-text available
In addition to the therapeutic agent, drugs contain excipients such as stabilizers, preservatives, solubilizers, or dyes, some of which are identical to additives in foods. Anaphylaxis to these excipients is probably an underestimated problem. After the first descriptions of anaphylactic reactions to drug excipients appeared more than 30 years ago,...
Article
Full-text available
Immediate-type hypersensitivity reactions (IHRs) to carboplatin (CA) are most commonly reported in ovarian cancer patients. A 54-year-old woman with stage IV melanoma suffering from metastasis in the entire right lower extremity was presented to our allergy outpatient clinic for diagnostic work-up due to an anaphylactic reaction with palmoplantar e...
Article
Full-text available
Background Although chronic urticaria (CU) is a common, cause of medical consulting both in general practitioners and allergist specialists worldwide, there is little information about its behavior and management in Latin America. Currently, national and international guidelines recommend using Omalizumab for cases refractory to management with ant...
Article
Full-text available
Background: Drug hypersensitivity reaction (DHR) is a common reason for an allergology con- sultation, during which it is not only necessary to gather a thorough medical history, but also to propose and perform diagnostic tests. Objectives: The aim of the study was to retrospectively assess the patients with a profile of preliminary drug hyperse...
Article
Full-text available
This rapid review summarises the most up to date evidence about risk factors for severe food‐induced allergic reactions. We searched three bibliographic databases for studies published between January 2010 and August 2021. We included 88 studies and synthesised the evidence narratively, undertaking meta‐analysis where appropriate. Significant uncer...
Article
Full-text available
Tree nuts are a powerful and common source of food allergens that induce IgE-mediated allergic reactions. Health authorities endorse the intake of tree nuts because they are regarded as nutritious. Allergic reactions to nuts can lead to severe and occasionally lethal reactions. Allergies to tree nuts are observed worldwide and are found in up to 4....
Article
Full-text available
Celiac disease is an immune-mediated enteropathy, caused (in genetically predisposed or susceptible individuals) by the ingestion of gluten, the complex of water-insoluble proteins found in cereal grains such as wheat, rye and barley. In terms of terminology, it is the complex natural history and extremely polymorphous clinical presentation that ha...
Article
Full-text available
In order to increase the effectiveness of allergen-specific immunotherapy in patients with pollen disease, the profile of allergen sensitization was determined at the molecular level, performed in 47 patients with clinical manifestations of seasonal rhinoconjunctivitis and perennial allergic rhinitis during a long time period. Allergic examination...
Article
Full-text available
Die Berechnungen des Intergovernmental Panel on Climate Change (IPCC) ergeben, dass das Klima bisher um ca. 1.0 °C gegenüber dem vorindustriellen Niveau zugenommen hat. Weitere Untersuchen zeigen darüber hinaus, dass die Klimaerwärmung besonderes im Alpenraum noch stärker ausgefallen ist. Die Auswirkungen dieser Klimaveränderung im Alpenraum zeigen...
Article
Full-text available
Infants and children with severe eczema and/or egg allergy have a higher risk of tree nut allergies, 1 among which, it is well known that cashew nut cross-react with pistachio nut. 2 A recent study reported an allergic association between cashew nut and pectin or citrus fruits. 3 Here, we report a case that had type-1 allergy to cashew nut and pect...
Article
Full-text available
Introduction: Bronchoscopic lung biopsy (BLB) is a widely used procedure. As the world's population is ageing, more BLBs are performed for older people with comorbidities. The aim of the study was to investigate if an older age is a risk factor for BLB related complications. Materials and methods: A prospective study at the Centre of Pulmonology...
Article
Full-text available
Introduction. Guidelines on Biological Therapy for Bronchial Asthma of the European Academy of Allergy and Clinical Immunology (EAACI) identified a number of controversial issues for additional outcome analysis using randomized clinical trials and data from routine clinical practice. In particular, there is unmet need to clarify algorithms for pres...
Article
Full-text available
Introduction Vaccination is the most important confirmed tool that can stop the ongoing coronavirus disease 2019 (COVID-19) pandemic, but the vaccination rate remains low in some countries, including Romania, despite consistent and undoubtedly scientific proof of this disease-prevention method. The risk of allergic reactions after COVID-19 vaccines...
Article
Full-text available
The worldwide use of COVID‐19 vaccines has shown that immediate allergic reactions to the ingredients are rare but should be clarified by means of an allergological work‐up. This review aims to highlight the current state of knowledge and possible pathogenesis based on the literature published to date. In addition to recording a detailed history an...
Article
Full-text available
Plant species have different degrees of allergenicity. Existing systems categorizing plants according their allergenicity were reviewed to find a method that could serve as the basis for the regulation of green areas. The categorization of plants by their allergenicity serves different purposes: informing allergic patients, warning consumers in hor...
Article
Full-text available
Background Expert national/global asthma management recommendations raise the issue whether a safe threshold of short-acting β2-agonist (SABA) use without concomitant inhaled corticosteroids (ICS) exists. Objective To examine SABA and maintenance therapy associations with severe asthma exacerbations across North America and Europe. Methods Observ...
Article
Full-text available
Background: When the coronavirus pandemic 2019 (COVID-19) emerged, concerns were also raised regarding the safety of allergen immunotherapy (AIT). The German Society for Allergology and Clinical Immunology (DGAKI) conducted a survey to collect real-world data on the daily routine of administering subcutaneous AIT (SCIT) and sublingual AIT (SLIT) d...
Article
Full-text available
The immune system interacts with many nominal ‘danger’ signals, endogenous danger‐associated (DAMP), exogenous pathogen (PAMP) and allergen (AAMP)‐associated molecular pattern molecules. The immune context under which these are received can promote or prevent immune activating or inflammatory mechanisms and may orchestrate diverse immune responses...
Article
Full-text available
Introduction: Basal cell carcinoma (BCC) is the most common malignant neoplasm of the skin. Management of patients with recurrent BCC remains a current clinical issue. Data concerning BCC recurrence rates as well as characteristics of this group of patients in the Polish population are scarce. Aim: Identification and analysis of clinical, epidem...
Article
Full-text available
Fish allergy is one of the most common food allergies. The currently recommended treatment commonly consists of avoiding all fish species. Recent literature suggests that these recommendations are overprotective for the majority of fish-allergic patients. This review summarizes recent findings and provides practical information regarding management...
Article
Full-text available
The Pacific oyster is a commercially important mollusc and, in contrast to most other shellfish species, frequently consumed without prior heat treatment. Oysters are rich in many nutrients but can also cause food allergy. Knowledge of their allergens and cross-reactivity remains very limited. These limitations make an optimal diagnosis of oyster a...
Article
Full-text available
Gender differences are increasingly emerging in every area of medicine including drug therapy; however, specific gender-targeted studies are infrequent. Sex is a fundamental variable, which cannot be neglected. When optimizing therapies, gender pharmacology must always be considered in order to improve the effectiveness and safety of the use of dru...
Preprint
Full-text available
Background One of the main barriers to vaccination against SARS-CoV-2 is the fear of developing hypersensitivity reactions to any of its components. Although these reactions are very rare, it is necessary to establish an effective protocol to detect patients at risk of developing them. The aim of this study was to evaluate hypersensitivity reaction...
Article
Full-text available
In the practical work of a phthisiatrician, a wide range of antimicrobial drugs is used daily to eliminate a specific pathogen. Due to organizational and a number of other reasons, including the absence of full - time clinical pharmacologists in many anti - tuberculosis dispensaries, whose work is inextricably linked with the implementation of phar...
Article
Full-text available
A novel, once-daily (o.d.), fixed-dose combination (FDC) of indacaterol acetate (IND), glycopyrronium bromide (GLY), and mometasone furoate (MF), delivered by the inhaler Breezhaler® device, is the first long-acting beta2-adrenergic agonist/long-acting muscarinic antagonist/inhaled corticosteroid (LABA/LAMA/ICS) therapy to be approved for maintenan...
Article
Full-text available
Guided tissue regeneration (GTR) and guided bone regeneration (GBR) became common procedures in the corrective phase of periodontal treatment. In order to obtain good quality tissue neo-formation, most techniques require the use of a membrane that will act as a barrier, having as a main purpose the blocking of cell invasion from the gingival epithe...
Article
Full-text available
Introduction: Phenotype I hypersensitivity reactions are the most commonly reported drug reactions; however, precision medicine has made it possible to characterize new phenotypes. A recent communication proposed the existence of a “converter phenotype,” which would affect patients who present non-immediate hypersensitivity reactions and in subsequ...
Article
Full-text available
Background: Allergic reactions after messenger RNA (mRNA)-based COVID-19 vaccines have been reported but detailed descriptions and further actions are not well characterized. Objective: To describe the symptoms of possible allergic reactions after the mRNA COVID-19 vaccine and outcomes of further vaccination. Methods: We descriptively analyzed data...
Chapter
Full-text available
Pollen is one of the main causes of allergic diseases in humans. Therefore, it is indispensable to develop and conduct effective treatment and prevention measures. For this purpose, detailed and differentiated information about the respective local exposure profiles for the individual patients is required. The present paper serves the purpose of te...
Article
Full-text available
Immunonutrition is an interdisciplinary field of research that unites knowledge and skills related to clinical nutrition, clinical immunology, infections and inflammation, injury and tissue damage. Immunonutrients are glutamine, arginine, taurine, leucine, cysteine, nucleotides, omega 3-polyunsatturated fatty acids (PUFA), vitamins and trace elemen...
Article
Full-text available
Costanzo A, Amerio P, Asero R, Chiricozzi A, Corazza M, Cristaudo A, Cusano F, Ferrucci SM, Nettis E, Patrizi A, Patruno C, Peris K, Picozza M, Stingeni L, Girolomoni G; Italian AD Study Group. Long-term management of moderate-to-severe adult atopic dermatitis: a consensus by the Italian Society of Dermatology and Venereology (SIDeMaST), the Associ...
Article
Full-text available
Allergic and immunologic skin diseases negatively impact the quality of life (QoL) of affected patients with detrimental consequences. Nonetheless, in everyday clinical practice the evaluation of QoL is often overlooked. Considering the increasing prevalence of atopic dermatitis, allergic contact dermatitis, hereditary angioedema, cutaneous mastocy...
Article
Full-text available
The aim of this study was to evaluate the clinical efficacy of combined allergen-specific immunotherapy (ASIT) in patients with allergic rhinitis (AR) with combined sensitization to pollen and household allergens. To achieve this goal, 49 patients with AR of working age were examined – 35.5±1.5 years with clinical manifestations of seasonal rhinoco...
Article
Full-text available
I have come across a letter to the Editor recently published in the “Advances of Dermatology and Allergology” titled: Pemphigus foliaceus complicated by sepsis of the aetiology of Yersinia enterocolitica after eating cheesecake (Adv Dermatol Allergol 2020; XXXVII (1): 111–113; DOI: https://doi.org/10.5114/ada.2018.78880).
Book
Full-text available
This is a handbook about component resolved allergen diagnosis
Article
Full-text available
Over the period 2002–2019, air temperature and precipitation significantly increased regionally for Bratislava, which could lead to phenological changes in some plant species. This study aimed to analyse the changes in the intensity, timing, and duration of pollen seasons of three allergological important plant taxa (Alnus, Poaceae, Artemisia) in t...
Article
Full-text available
Hypersensitivity reactions are an important aspect of perioperative care and are a crucial interdisciplinary issue in anaesthesiological practice, as well as allergological and laboratory diagnostics. This phenomenon was observed as early as the 1980s and 1990s in Western European countries, and knowledge on this subject has grown significantly ove...
Article
Full-text available
Introduction: Allergic contact dermatitis (ACD) constitutes a considerable part of allergic morbidity among the population, although its actual prevalence is unknown as it is often not properly diagnosed. Aim: To determine the incidence of ACD compared to other allergic dermatoses in patients from the Russian Federation and the People's Republic...
Article
Full-text available
The prevalence of allergic diseases is regarded as one of the key challenges in health worldwide. Although the precise mechanisms underlying this rapid increase in prevalence are unknown, emerging evidence suggests that genetic and environmental factors play a significant role. The immune system, microbiota, viruses, and bacteria have all been link...
Article
Full-text available
Granulocyte-macrophage colony-stimulating factor (GM-CSF) belongs to the group of growth cytokines (hematopoietins) that regulate proliferation and differentiation of myeloid lineage cells. Recently, a lot of new data have accumulated, indicating the presence of a number of previously unknown biological effects in GM-CSF and synthetic peptides of i...
Article
Full-text available
Background: Nut allergies are an increasingly frequent health issue in the pediatric population. Tree nuts (TN) and peanuts are the second cause of food anaphylaxis in Italy. Unfortunately, knowledge of the clinical characteristics of a TN allergy in Italian children is limited. Our study aimed to identify the clinical and allergological character...
Article
Full-text available
Background Perioperative anaphylaxis is a severe immediate hypersensitivity reaction to drugs administered in immediate temporal association to surgical procedures. The European Academy of Allergy and Clinical Immunology recommends allergologic tests be performed within the golden period of between 1 and 4 months after the date of the event to avoi...
Article
Full-text available
Karolina Świerczyńska, Rafał Białynicki-Birula, Jacek C Szepietowski Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Jacek C SzepietowskiDepartment of Dermatology, Venereology and Allergology, Wroclaw Medical University, 1 Chalubinskiego Street, Wroclaw, 50-368, PolandTel +48 601 53...
Article
Full-text available
Systemic mastocytosis (SM) is a heterogeneous group of diseases that affect almost exclusively adults and are defined by the proliferation and accumulation of clonal mast cells (MC) in various tissues. Disease subtypes range from indolent to rare but aggressive forms. Although SM is classified as a rare disease, it is believed to be likely underdia...
Article
Full-text available
Introduction: Basal cell carcinoma (BCC) is the most common cancer in humans, but the reporting of patients with BCC is still not complete. There are a limited number of analyses in the literature on BCC epidemiology. Aim: To study the epidemiological as well as clinical aspects of BCC by analysing a single centre's experience in the Lower Siles...
Article
Full-text available
Background mRNA based COVID-19 vaccines have been reported to induce hypersensitivity reactions (HSR) in a small number of individuals. We aimed to evaluate the real-world incidence of the BNT162b2 mRNA COVID-19 vaccine HSR and to determine the value of the basophil activation test (BAT) in the allergological workup of patients reporting these reac...