Alcohol Addiction - Science topic

Background The COVID-19 pandemic and lockdowns had a significant impact on mental well-being and (mental) healthcare systems globally. Aims To describe trends and dynamics of out-patient prescribing of psychotropic medications during the COVID-19 pandemic in The Netherlands. Method Dispensed psychotropic medication prescriptions during the COVID-...

El objetivo de esta revisión es dar cuenta de las repercusiones psicosociales que conllevan las conductas adictivas en adolescentes. Entre las adicciones más comunes se encuentran: la adicción al alcohol, a la marihuana, y al uso del móvil o celular. Todas ellas tienen gran repercusión en las actividades del cotidiano, afectando directamente sobre...

The mesolimbic dopamine system is crucial for drug reinforcement and reward learning, leading to addiction. We previously demonstrated that Arvcf was associated significantly with nicotine and alcohol addiction through genome-wide association studies. However, the role and mechanisms of Arvcf in dopamine-mediated drug reward processes were largely...

Alcohol use Disorder( AUD) poses a significant global public health challenge due to its widespread prevelance and substantial impact on individuals and society. Depsite existing pharmacological and psychosocial interventions, treatment outcomes remain varied abd often suboptimal. This review explores the efficacy, safety and mechanistic actions of...

Stimmungsstörungen Im Bereich des Substanzmissbrauchs treten depressive und ängstliche Symptome (zusammen mit einer Vielzahl anderer psychologischer Symptome) oft vorübergehend auf und stehen im Zusammenhang mit den Auswirkungen der konsumierten Substanzen, dem Entzugsprozess oder psychosozialen Stressfaktoren, die für den Lebensstil des Einzelnen...

This study examined the health status and mortality of a cohort of persons experiencing homelessness (PEH) over a 15-year period in Girona, Spain. A prospective analysis was conducted on a cohort of 855 PEH from 2006 to 2021, with sociodemographic and clinical data gathered from public health and social records. During the follow-up period, 6.4% of...

Mood disorders Within the domain of substance abuse, depressive and anxious symptoms (along with a plethora of other psychological symptoms) are often transient and associated with the effects of the abused substances, the withdrawal process, or psychosocial stressors that are characteristic of the individual's lifestyle.The detoxification process...

La morbilidad y mortalidad asociadas al consumo de alcohol continúan en aumento. Aunque existen diversos tratamientos farmacológicos y no farmacológicos para la adicción al alcohol, el craving es uno de los principales factores que desencadenan recaídas. Por ello, resulta crucial desarrollar estrategias innovadoras para manejar y regular el craving...

The study focuses on the complex interconnection of race, sexuality, and socioeconomic background in shaping the stories of mothers struggling with addiction disorders as they attempt to recover from traumatic experiences. A sample of 45 mothers was employed in the study. Using case study analysis methodologies, the stories of 6 mothers were used a...

Objectives A significant subset of patients with mental health disorders (MHDs) fail to respond to standard management and are termed as treatment-resistant. This cohort has limited options for managing their condition. Autonomic dysfunction has been reported in the neurobiology of MHDs including anxiety, depression, obsessive-compulsive disorder (...

Alcohol addiction is a significant public health issue worldwide, leading to various physical, psychological, and social problems. This manuscript explores the role of family physicians within the discipline of family medicine in managing alcohol addiction, emphasizing the importance of a comprehensive approach that incorporates lifestyle medicine...

Objective: This study focuses on the growing concern of mental disorders combined with alcohol addiction, highlighting the need for medical examination by both narcology and psychiatry specialists. The objective is to explore the challenges related to the prevention, treatment, and rehabilitation of this comorbid condition. Methods: A comprehensive...

Background/Objectives: In brain physiology and disease, MMP-9 is a significant and apparently peculiar factor. Numerous studies have implicated neuroinflammatory processes involving MMP-9 in the pathophysiology of addiction. This study aims to evaluate plasma MMP-9 level as a biomarker for the stages of alcohol and opioid addiction. Methods: The ca...

Background and Objectives: Multiple evaluations of oxidative stress in individuals with substance use disorder show elevated levels compared to non-substance-abusing individuals. Information concerning antioxidant defense mechanisms in relation to alcohol and opioid dependence is variable and sometimes contradictory. The objective of the present in...

Alcohol is the second-most misused substance after tobacco. It has been identified as a causal factor in more than 200 diseases and 5.3% of all deaths and is associated with significant behavioral, social, and economic difficulties. As alcohol consumption may modulate the immune system’s regulatory mechanisms to avoid attacking the body’s tissues,...

The aim of this work is to develop a model of alcohol that takes drug features into account. We assess the model feasibility and explain its formulation in terms of a nonlinear differential equation. Using the subsequent matrix generation technique, we ascertain the reproductive number in order to assess the dynamics of the model. We also examine t...

It has been shown that structural changes occur in the brain in many types of addiction and can have an impact in maintaining addictive behavior and can be improved with treatment. The aim of this study was to identify structural changes in the brain's reward system in alcohol use disorder. Structural magnetic resonance imaging was employed to comp...

Alcohol and substance addiction is a growing problem both globally and in Turkey which renders individuals' lifelong wellbeing. The current study investigates the moderator role of flourishing in the relationship between alcohol and substance addiction and risk-taking behavior tendencies among adults. A cross-sectional study design was conducted an...

The ability of environmental cues to trigger alcohol‐seeking behaviours is thought to facilitate problematic alcohol use. Individuals' tendency to attribute incentive salience to cues may increase the risk of addiction. We sought to study the relationship between incentive salience and alcohol addiction using non‐preferring rats to model the hetero...

Aims Research indicates that shared and specific underlying factors influence different addictions, sometimes resulting in co-occurring problems. The evidence concerning risk and protective factors for gambling and alcohol addiction, along with their co-occurrence, remains ambiguous. To address this gap, this study will conduct longitudinal researc...

The article addresses the issue of self-awareness in men with alcohol addiction. This model includes the micro-level, exo-level, meso-level, macro-level, and an individual internal vector of self-awareness. At the micro-level (the family as the closest environment of codependent individuals), the focus is on the psychological conditions in which th...

Background: The quality of life among tribal members who care for people with alcohol addiction

Background: Many clinical trials indicate that baclofen, a gamma-aminobutyric acid agonist has efficacy for alcohol dependence to reduce the cravings of alcohol and it may also have certain common or rare ADRs. Aim was to evaluate tablet baclofen’s adverse effects and sociodemographic profile in the treatment of ADS. Methods: This study was carried...

Introduction This extensive literature review investigates the relationship between post‐traumatic stress disorder (PTSD) and alcohol use disorder (AUD), focusing on the neurobiological changes associated with their co‐occurrence. Given that these disorders frequently coexist, we analyze mechanisms through which alcohol serves as a coping strategy...

One hundred and four Million tribal people live in India, which accounts for 8.6% of the country’s population. The Union Cabinet on 15th November 2023 approved the Pradhan Mantri Janjati Adivasi Nyaya Maha Abhiyan (PM-JANMAN) aiming to reach out to over twenty-two thousand particularly vulnerable Tribal groups (PVTG) tribal habitats over two hundre...

This study aims to understand the impacts of alcohol addiction on individuals' social and economic lives. Semi-structured interviews were conducted with 15 alcohol-dependent participants residing in Düzce, and demographic data were collected and analysed through content analysis. The average age of participants is 43.46, predominantly comprising me...

Marketing analysis was conducted and the availability of drugs for the treatment of alcohol addiction under the ATX code N07BB was assessed. The study covers three main clinical and pharmacological groups: Disulfiram (N07BB01), Naltrexone (N07BB04) and other drugs (N07BB10). The features of the release forms (tablets, granules, powders), availabili...

Non-invasive brain stimulation offers a painless and safe approach to neurological rehabilitation, providing minimal side effects, and has been used by thousands of people worldwide. Non-invasive brain stimulation modulates the brain's excitability to aid in treating neurological disorders. The latest work has moved well beyond implementations of t...

Disulfiram, a synthetic drug, has historically played a significant role in the treatment of alcoholic liver disease as the first medication approved by the U.S. Food and Drug Administration for alcohol use disorders. Beyond its efficacy in inhibiting alcohol addiction and treating alcoholic liver disease, disulfiram has also demonstrated potential...

The phenomenon of alcohol addiction in Indonesia has rapidly spread across various demographics, from the elderly to the youth. A strategic approach to addressing this issue involves drawing upon the gradual prohibition of alcohol (khamr) established during the Prophet Muhammad’s time. This study aims to examine the stages and processes of khamr pr...

Enhancing the Rehabilitation of Communities Affected by Drug and Alcohol Addiction Through Psychological Holistic Care: This article proposes a resource-based empowerment approach to psychological counseling aimed at supporting individuals in their recovery from substance addiction

De acordo com a Organização Mundial da Saúde (OMS), um alcoólico é definido como um indivíduo que consome álcool em excesso e cuja dependência está associada a perturbações mentais, problemas de saúde física, dificuldades nas relações interpessoais e alterações no comportamento social e económico (Oliveira et al., 2022). Nos últimos anos, o consumo...

En la actualidad, Guatemala es uno de los paises con mayor consumo de alcohol, para la sociedad guatemalteca, el ingerir bebidas alcoholicas, es sinonimo de fiesta y de compartir con amigos o familiares, se tiene la costumbre de hacerlo en todos los ambitos donde se desenvueven los seres humanos lo que conlleva consecuencias nefastas como violencia...

Patients with alcohol use disorder (AUD) who seek treatment show highly variable outcomes. A precision medicine approach with biomarkers responsive to new treatments is warranted to overcome this limitation. Promising biomarkers relate to prefrontal control mechanisms that are severely disturbed in AUD. This results in reduced inhibitory control of...

Alcoholism is characterized by persistent and uncontrollable consumption of alcoholic beverages, which poses significant risks to physical, psychological, and emotional health, including conditions such as liver cirrhosis, epilepsy, cancer, hypertension, and diabetes. Furthermore, it contributes to substantial social and economic challenges, includ...

Objective: This study aims to assess the external validity of the Alcohol Use Disorders Identification Test (AUDIT) in Swedish prenatal care as an indicator for alcohol-addiction disorders, and to characterize women with mismatched information in healthcare registers Design: This study was designed as a National register-based study. Setting: Swede...

Introduction Child labor is an important issue of public health in both developed and developing countries. This is a cross-sectional-descriptive study. Methods 418 individuals under the age of 18 were enrolled in the study. Data were collected by using a questionnaire. The data were analyzed using SPSS 22 software package. Significance was p < 0....

Background Both night-eating syndrome and binge-eating disorder are characterized by episodes of excessive food consumption, significant distress, and functional impairment related to maladaptive eating behaviors. Both types of eating disorders are associated with poorer sleep quality. Cognitive behavioral therapy has demonstrated good outcomes for...

Objetivo: analizar la relación entre la inteligencia emocional, la motivación para el cambio y el estrés provocado por el consumo de alcohol y drogas de personas que están en tratamiento contra la adicción en una región del norte de México. Metodología: diseño descriptivo correlacional con una muestra de 62 hombres. Resultados: el 35.5% de los entr...

Background The discovery of biomarkers in chronic subdural haematomas (CSDH) suggests that inflammation is part of CSDH pathophysiology. It is unknown whether inflammation reflects an independent CSDH driver or haematoma degeneration. This knowledge holds a potential target for anti-inflammatory treatment in patients at risk of CSDH. This study inv...

Introducción: Más de 2.300 millones de personas en el mundo consumen alcohol debido a factores culturales y económicos, lo que provoca serios problemas de salud y sociales, contribuyendo al 5,3 % de las muertes globales. Las personas que han desarrollado trastornos de salud y adicciones derivados de conductas de riesgo con alcohol conviven de maner...

Se aborda desde aspectos biológicos (sistema nervioso) y sociales (representaciones y estereotipos) el fenómeno de la adicción al alcohol con estudiantes de secundaria.

Introduction : The research aimed to assess the linkages between alcohol propensity and stress and coping styles in young adults during the COVID-19 pandemic. The project also focused on investigating the significance of differences in alcohol propensity, taking into account selected sociodemographic characteristics. Material and methods : A total...

Drunk: Nietzsche, Hemingway, Erdős, Cantor, Beethoven, Dostoevsky, Poe, Joyce, van Gogh, Rousseau, and Fields explores the profound impact of alcohol on the lives and works of eleven influential figures across philosophy, literature, mathematics, music, art, and comedy. From Friedrich Nietzsche's philosophical critique of "narcotics" to Vincent van...

Background Eliminating hepatitis C virus (HCV) infections is a goal set by the World Health Organization. This has become possible with the introduction of highly effective and safe direct-acting antivirals (DAA) but limitations remain due to undiagnosed HCV infections and loss of patients from the cascade of care at various stages, including those...

Alcohol use disorder’s complexity arises from genetic and environmental factors, with alcohol metabolism genes and neurotransmitter pathways being critical. This study aims to analyze synaptic plasticity gene expression changes in individuals with AUD in order to study their contribution to AUD development and to identify potential biomarkers of tr...

Background Cardiomyopathy, a rare heart disease, is characterized by abnormalities in cardiac wall thickness and chamber size, leading to impaired contraction, relaxation, conduction, rhythm, and reduced pumping ability. Aim This review aims to provide a comprehensive understanding of cardiomyopathy by examining its various aspects Method A liter...

Purpose Acute alcohol intoxication (AAI) is a life-threatening medical condition resulting from excessive alcohol consumption. Our research revealed the potential of morin (MOR) in treating AAI. However, MOR’s effectiveness against AAI was hindered by its poor solubility in water and low bioavailability. In this study, our aim was to develop a self...

Aim: The aim of this study was to identify and elucidate the differences between highly affiliated and low/non-affiliated participants in Alcoholics Anonymous (AA) meetings. Methods: A qualitative study of 24 participants was conducted in Romania between March and June 2021. Data were collected by means of in-depth interviews. Thematic analysis was...

A mathematical model of the dual addiction dissemination dynamics of alcoholism and smoking was created and examined in this work, along with cost-effectiveness and optimal control techniques. The primary goal of the research is to determine which cost-efficient management techniques are most helpful in lowering the problem of dual addiction disper...

Consumption of low-alcohol products by young people is due to the erroneous opinion that they are safe for health. However, against the background of taking low-alcohol drinks, addiction quickly forms and complications develop, including lipid metabolism disorders. Studies show that consumption of low-concentration ethanol-containing drinks changes...

Introduction and aim. Since February 24, 2022, military personnel of the Ukrainian Defense Forces have been resisting the military aggression of the Russian Federation. After participating in combat operations, military personnel accumulated combat stress. Drinking alcohol was one of the ways to overcome it. The purpose of the article is to identif...

p style="text-align: justify;">The article presents results of the research into self-perception of males and females diagnosed with chronic alcoholism. The article’s data is theoretically based on the analysis of contemporary scientific studies which indicate a number of discrepancies identified in certain qualitative characteristics of alcohol ad...

Annotation. The process of forming alcohol addiction leads to the occurrence of irreversible changes in the human body, which can be fatal. Neurons of the brain are among the most sensitive structures to the effects of ethanol. Brain neurons are one of the most sensitive structures to the action of ethanol. Understanding the mechanism of formation...

Background: The present study aimed to explore women's perception of men with different addictions in terms of their short- and long-term mate value. Objectives: 2,525 women (age range: 18-40, M = 28.35, SD = 6.39) were randomized to six conditions in a vignette-based experiment where a male of otherwise high mating value was described as suffering...

The paper outlines the role of affective temperaments, as defined by Akiskal, in the development and maintenance of alcohol use disorders with a particular focus on the clinical course of addiction. Among affective temperaments, a cyclothymic temperament seems to play a key role in the development and maintenance of alcohol use disorders, and have...

Aim: Mood disorders are significantly connected with sexual functioning impairment among women. The aim of this study was to assess and describe specifics of sexual expression and its dysfunction in groups of women diagnosed with bipolar disorders (F31), major depressive disorder (F32 and F33) and persistent mood disorders (F34). Material and Metho...

Dans ce travail, l’objectif principal est d’explorer les effets et l’efficacité du diéthylamide de l'acide lysergique, plus communément connu sous le nom de LSD, dans le traitement du trouble lié à l’usage de l’alcool. Une recherche systématique, s’appuyant sur différentes bases de données, a été menée dans le but de sélectionner des articles trait...

The paper reviews the literature on alcohol dependence and a form of support based on the assumptions of logotherapy. The concept of alcohol dependence is defined, and the main symptoms are listed on the basis of the ICD-11 and DSM-5 classifications. A reflection is made based on previous research on the factors affecting the onset of alcoholism. B...

According to a survey regarding indigenous employment, in Taiwan, a high proportion of indigenous people are engaged in construction work compared with the overall population. However, among indigenous construction workers, 56.15% have received no occupational safety or health training, and 9.39% have encountered occupational accidents in their wor...

Background Eliminating hepatitis C virus (HCV) infections is a goal set by the World Health Organization. This has become possible with the introduction of highly effective and safe direct-acting antivirals (DAA) but limitations remain due to undiagnosed HCV infections and loss of patients from the cascade of care at various stages, including those...

The sorites problem often arises for wrongdoing. In cases of substance use, a father has a drink, which, by itself, does not result in alcohol addiction. But he has another drink and another, until he develops an alcoholism that results in severe harm to his wife and children. Such cases present an interesting puzzle for thinking about moral respon...

Background There are few efficient treatment options for alcohol addiction, which continues to be a serious public health concern. The possible contribution of gut microbiota to the onset and progression of alcohol addiction has been brought to light by recent studies. Probiotics have become a cutting-edge intervention in the treatment of alcohol c...

Health and Social risks related to marijuana and alcohol are a serious problem in the United States. This research tried to introduce OLS regression in order to figure out the correlation between use of alcohol and cannabis, and the trend before and after legalization of cannabis, which is a factor that has not been researched in previous literatur...

Introduction Chronic alcoholism can result in severe liver conditions such as fatty liver disease and cirrhosis, potentially leading to life-threatening complications and premature death. Objectives This study investigated the age-sex distribution of patients with alcohol addiction and aimed to identify differences in clinic department preferences...

Introduction Liver cirrhosis, a chronic liver disease, can be closely linked to chronic alcohol abuse, posing a significant medical challenge. Hepatic encephalopathy (HE), a neuropsychiatric condition resulting from liver dysfunction, commonly occurs in cirrhotic patients due to the accumulation of neurotoxic substances like ammonia and manganese i...

Introduction Alcohol addiction can lead to withdrawal seizures, but most patients do not develop epilesy. In some cases a permanent complication occurs - symptomatic epilepsy. In other cases epilepsy precedes alcohol addiction. Comorbidity may pose serious chalenges to treating clinicians. There are conflicting data regarding relationship between a...

Introduction In Switzerland, alcohol consumption is even decreasing, with an exception for old people after retirement.35%of them have a heavy or addictive consumption (OFSP, consommation d’alcool en Suisse, fait et chiffres. 01.2023). This is also the case for home residents. The alcohol consumption by old poeple has negatives consequences on the...

Introduction Many individuals who suffer from one or multiple substance use disorders often also struggle with another co-morbid psychiatric condition, primarily anxiety disorders. As substance dependency develops, the loss of self-control becomes a pivotal issue, leading to challenges in self-esteem and self-respect. These challenges subsequently...

Introduction The mortality rate among individuals experiencing homelessness tends to be premature and is linked to mental disorders and chronic diseases. In Spain, there is a significant gap in the study of mortality among individuals in situations of residential exclusion with real clinical data. Objectives This study aims to analyze mortality am...

Zusammenfassung Hintergrund Langzeitbetrachtungen der Alkoholabhängigkeit können Aufschluss zu Ätiologie, Prävention und therapeutischer Versorgung bieten. Ziel Beschreibung empirischer Befunde zur Entwicklung in eine Alkoholabhängigkeit hinein und Entwicklungen aus ihr heraus. Methodik Narrative Literaturrecherche, Analyse von Ergebnissen aus K...

The prevalence of suicide behavior among university students has been an issue of great concern because of its upward trend. This paper examines suicide ideation in relation to gender and the variation of correlates in different universities among university students in the Nyanza region, Kenya. The objectives of the study were to determine gender...

Background. Alcohol consumption (alcoholism) is one of the most common health risk factors, usually originating in adolescence. Aims — to identify the main trends and features of alcoholization of Russian teenage schoolchildren at the beginning of the 21st century. Methods. The Center for Monitoring Bad Habits among Children and Adolescents of the...

Introduction Post-pandemic alcohol consumption is on the rise due to people starting to adapt themselves to the practice of consuming alcoholic beverages at home. In addition to the direct effects of intoxication and addiction, estimates suggest that alcohol contributes to approximately 20-30% of global cases of oesophagal cancer, liver cancer, cir...

Purpose: Alcohol use disorder continues to be a public health concern, and even after treatment, the relapse rate is still high. The family support systems are closely related to alcohol addiction recovery. However, studies on psychological mechanisms between the two are rare. Therefore, we aimed to explore the mediating role of continuing care ser...

Introduction Current literature does not dispose from a widely accepted definition of recovery in alcohol use disorder (AUD), and most proposals originate from anglophone countries. This study introduces a pioneering consensus in Spain on the definition of recovery in AUD. Method The Delphi method was used. The expert panel, comprising 54 multidis...

Les comportements addictifs en général et la dépendance à l'alcool et aux drogues en particulier sont un des défis les plus complexes auxquels fait face la psychiatrie contemporaine. Outre la forte comorbidité psychiatrique associée, le patient souffrant d'addiction est confronté à des problèmes psychologiques, sociaux et spirituels. Une approche h...

Introduction: Alcohol and substance use disorders are important public health problems with an increased risk for bloodborne and sexually transmitted infections. Objectives: To determine the frequency and risk factors of hepatitis B, hepatitis C and HIV in individuals with drug and alcohol addiction. Methodology: This prospective study was conducte...

Introduction Our study aimed to compare meditation and compassion-based group therapy with the standard of care in patients with eating disorders, drug addiction, alcohol addiction, and depression, concerning acceptance, mindfulness awareness, self-compassion, and psychological distress. Methods A controlled designed study was performed, comparing...

Genetic features of alcohol dependence have been extensively investigated in recent years. A large body of studies has underlined the important role of genetic variants not only in metabolic pathways but also in the neurobiology of alcohol dependence, mediated by the neuronal circuits regulating reward and craving. Serotonin transporter (5-HTT), en...

Abnormal experiences of time (ATEs) are an established object of research in phenomenological psychopathology. Objective: The purpose of this study was the first validation of the Transdiagnostic Assessment of Temporal Experience (TATE), a structured phenomenological interview concerning ATEs in individuals with diverse mental health conditions, an...

Suicidal behaviors have been on the rise among university students in the recent past. The aim of this paper was to examine suicide ideation in relation to age category and correlates among university students in the Nyanza region with the aim of preventing occurrences of completed suicide. The objectives of the study were to determine the differen...

Categories: Psychiatry Editorial Nach den Gesetzen des Marktes besteht eine Wechselwirkung zwischen dem Verbraucher und damit der Nachfrage und dem Markt, oder besser dem Angebot, das im Zuge der Globalisierung immer mehr dazu tendiert, den Verbraucher zu schwächen; es ist der Markt selbst, der Bedürfnisse schafft und sie gleichermaßen befriedigt....

Objective The ReLink project aims to reintegrate diagnosed-but-untreated hepatitis-C-positive patients into medical care and initiate a therapy. Material/methods A retrospective search within the practice management system of a single center in Germany identified among 1965 hepatitis-C-positive patients 100 untreated patients with available contact...

After reviewing George's Case record, I noticed several relevant details. First, under the presenting problem heading, George is not willing to the treatment of his alcohol addiction. For example, George's case record states, 'George did not seem committed to being there. He didn't feel he had a problem' (Georges Case Record). This is relevant beca...

This cross-sectional analysis aimed to assess the quality of life (QoL) among hospitalized patients with alcohol use disorder (AUD) in Romania, utilizing the WHOQOL survey. Conducted from January to December 2023 in the Psychiatry Clinic of the “Pius Brinzeu” Emergency Clinical Hospital in Timisoara, this study engaged 70 participants, adhering to...

In this study, persons who suffer from alcohol addiction disorders are examined to determine how the use of relaxation techniques and biofeedback affects their mood swings, sense of control, and overall quality of life for themselves. “The purpose of this study is to investigate the ways in which these therapies have the ability to alleviate the ps...

Chronic alcohol consumption poses significant public health challenges globally. In underserved regions, the lack of AI-based interventions for alcohol addiction highlights a critical gap in the healthcare system, particularly regarding the early detection of alcohol abuse. Henceforth, this research aims to raise awareness of alcohol use disorder a...

HIV/AIDS is one of the most devastating infectious diseases affecting humankind all over the world and its impact goes beyond public health problems. This study was conducted to investigate the joint predictors of hemoglobin level and time to default from treatment for adult clients living with HIV/AIDS under HAART at the University of Gondar Compr...

Introduction: Criminology is the study of crime and criminal acts. The Maluku province has a local alcohol soothing drink, namely, Sopi which is the result of calming sap or sweet liquid obtained from plant stems, and is produced by people for generations on various islands in Maluku. Sopi is produced from the mayang tree (sageru) and is then proce...

Kudzu root (Puerariae Lobatae Radix) is the tuberous root of Pueraria lobata, family Leguminosae. Kudzu root contains a variety of beneficial active ingredients such as puerarin, daidzin, daidzein, genistenin, 3′-hydroxy puerarin, β-sitosterol, stigmasterol, arachidic acid, and so on. Modern medical research shows that active ingredients in kudzu r...

This study investigated the effects of zonisamide treatment on cerebellar tissues in an experimental alcohol addiction (AA) model and its potential mechanisms of action, particularly regarding apoptotic protease activating factor-1 (APAF-1) and tumor necrosis factor-alpha (TNF-α) expression. Thirty rats were divided into three groups: sham, ethanol...

Hepatocellular carcinoma (HCC) has become the fourth leading cause of cancer-related deaths worldwide; annually, approximately 830,000 deaths related to liver cancer are diagnosed globally. Since early-stage HCC is clinically asymptomatic, traditional treatment modalities, including surgical ablation, are usually not applicable or result in recurre...

A growing body of evidence indicates the existence of abnormal local and long‐range functional connection patterns in patients with alcohol use disorder (AUD). However, it has yet to be established whether AUD is associated with abnormal interhemispheric and intrahemispheric functional connection patterns. In the present study, we analysed resting‐...

Several books and articles published in the last few decades have looked at how alcohol use has affected the job market globally. This study attempted to determine how specific labour market shocks (such as losing a job) influence alcohol intake on an individual level to clarify the existing research. We went deeper into the subject of whether or n...

Alcohol use disorder is a medical condition marked by a diminished capacity to halt or manage alcohol consumption, even in the face of detrimental social, professional, or health outcomes. It encompasses various terms such as alcohol abuse, dependence, addiction, and colloquially, alcoholism. Research has consistently highlighted the significant to...

La phase de transition entre 55 ans et l'âge avancé amène de nombreux changements pour les personnes concernées, que ce soit au niveau psychique, physique ou socioprofessionnel. Dans le contexte du vieillissement de la population, les prises en charge des personnes souffrant de problèmes d'alcoolodépendance dans cette tranche d'âge prennent plus d'...