Science topics: MedicineInternal MedicineGeriatric MedicineAging Research
Aging Research - Science topic
Explore the latest questions and answers in Aging Research, and find Aging Research experts.
Questions related to Aging Research
There must be a reason to work, so there must be an idea of pursuing research career. Let us share our experiences and motivate others.
Do you have any idea of how it may impact the following -
What are Health effects ?
How it effects sustainability ?
Is there any study on growth impacts ?
What about energy and environment ?
How it impacts the ecology and environment ?
How it impacts the local economy ?
The role of anti-aging genes such as Sirtuin 1is involved in epigenetics and is critical to the treatment of various diseases such as NAFLD, obesity, diabetes and neurodegenerative diseases. Sirtuin 1 is critical to the immune system and its repression is connected to the various chronic diseases. The role of RNA editing and genetic engineering is now important to treating various chronic diseases in the presence of Sirtuin 1 repression to prevent and reverse various chronic diseases that are linked to mitochondrial apoptosis and programmed cell death. RELEVANT REFERENCES:
A. Anti-Aging Genes Improve Appetite Regulation and Reverse Cell Senescence and Apoptosis in Global Populations. Advances in Aging Research, 2016, 5, 9-26
B. Single Gene Inactivation with Implications to Diabetes and Multiple Organ Dysfunction Syndrome. J Clin Epigenet. 2017;Vol. 3 No. 3:24.
C. Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries. Top 10 Contribution on Genetics. Chapter 1, EBook. 2018. www.avid.science.com
I have tried with no success various UV-B stresses but I did not find an increase in beta galactosidase.
What is the current evidence regarding the relationship between telomere shortening and exercise??
Our research team focuses on aging research. We have various projects going through this year that would benefit from a cooperation with lab that is capable of measuring shortest telomeres, for example by the TeSLA method (see the link below), which we due to insufficient human capital are incapable of right now.
In case you are interested in a cooperation (short term or long term) please contact me.
I have Submitted 2,3 Papers in Science Direct associated Journals but the time of the first decision has been ended so What should I do? Could I email them to remind them about the first decision?
What would be the main long-term physiological and bimolecular adaptations that could differentiate endurance and sprinters master athletes? Taking into considerations the already known outcomes discussed by Kusy and Zielinsk.
Kusy, K., & Zielinski, J. (2015). Sprinters versus long-distance runners: how to grow old healthy. Exercise and sport sciences reviews, 43(1), 57-64.
Hi All, I am looking at compiling a wide list of papers or resources on reminiscence therapy for dementia for older people. The positive and negative results, Creative approaches, ICT interventions, standard procedures, etc. I'm interested in perspectives from differing disciplines. All resources/ papers/ leads welcome Thank you!
1. What type of literature should I read for writing a successful concept note?
2. Is there any literature which will help me decide a research question/objective for designing a study will be appropriate for the evaluation of community-based primary prevention models for NCDs?
3. For convincing the donor as a student researcher is it better that I narrow down to a specific prevention model such as Mass Health promotion to reduce NCD, e.g. Hypertension.
a) Do you think a base-line survey of knowledge regarding prevention vs end-line survey will be a strong method of evaluation?
b) If I try to do an RCT - which literature will help me find out what community-based primary preventions interventions recent or interesting?
(This is for an assignment)
PhD is considered as the highest degree one can get from the university and also is recognized worldwide. What is expected out of a PhD degree, the holder and the providing institutes ? What are expectations of society and science from them ?
Do you have any idea of how it may impact the following -
What are Health effects ?
How it effects sustainability ?
Is there any study on growth impacts ?
What about energy and environment ?
How it impacts the ecology and environment ?
How it impacts the local economy ?
1. Martins IJ. Advances in Aging and Health Research. Scientific Research Publishing, Inc. ISBN: 978-1-61896-569-1
2. Martins IJ. Scientific Nutritional Health and Global Chronic Disease. Scientific Media. New Distribution Report. 2018;443:1-3
3. Martins IJ. Chapter 01. Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries. Top 10 Contribution on Genetics. Book Chapter. 2018. www.avid.science.com
4. Martins IJ. Anti-Aging Gene linked to Appetite Regulation Determines Longevity in Humans and Animals. International Journal of Aging Research. 2018,1(6): 1-4.
5. Martins IJ. Antimicrobial activity inactivation and toxic immune reactions induce Epilepsy in human. J Med Discov (2017);2(4):jmd17040.
6. Martins IJ. Single Gene Inactivation with Implications to Diabetes and Multiple Organ Dysfunction Syndrome. J Clin Epigenet. 2017;3:24.
A country trying hard to its level best for making urbanization, industrialization and does not care about deforestation, pollution and its natural resources, what will be the end cause of that country in such a situation? and What is Sustainable Development?
Autonomy is a desirable goal at any age. It's the main goal of different national and internacional entities related to ageing; even more in Spain, the 2nd country in the world with the highest life expectancy after Japan.
Bacterial lipopolysaccharides (LPS) are endotoxins and essential components of the outer membrane of all Gram-negative bacteria and consist of covalently linked segments, surface carbohydrate polymer, core oligosaccharide acylated glycolipid (LIPID A) and can bind to cell membranes to alter membrane interactions with relevance to virus entry and virus inactivation. LPS can induce metabolic disease and neurodegenerative diseases. Food quality is of critical relevance to LPS contamination in individuals and may determine the severity of the Coronavirus COVID 19.
1. Bacterial Lipopolysaccharides and Neuron Toxicity in Neurodegenerative Diseases. Neurology Research and Surgery. 2018; 1(1): 1-3.
2. Antimicrobial Drugs and Bacterial Amyloid Peptide Induce Toxic Manifestations in Chronic Diseases. EC Pharmacology and Toxicology 6.1 (2018): 01-04.
3. Antibiotic Resistance Involves Antimicrobial Inactivation in Global Communities. SAJ Pharma Pharmacol 2017;2: 102.
4. Bacterial Lipopolysaccharides Change Membrane Fluidity with Relevance to Phospholipid and Amyloid Beta Dynamics in Alzheimer’s Disease. J Microb Biochem Technol. 2016; 8: 322-324.
5. Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci. 2015; 16(12): 29554–29573.
6. Food quality induces a miscible disease with relevance to Alzheimer’s disease and Neurological diseases, J Food Research, vol. 5, pp.45-52, 2016
7. Unhealthy Diets Determine Benign or Toxic Amyloid Beta States and Promote Brain Amyloid Beta Aggregation. Austin J Clin Neurol 2015;2(7): 1060-66.
8. LPS Regulates Apolipoprotein E and Aβ Interactions with Effects on Acute Phase Proteins and Amyloidosis. Advances in Aging Research 03/2015; 4(2):69-77.
9. The Future of Genomic Medicine Involves the Maintenance of Sirtuin 1 in Global Populations. Int J Mol Biol . 2017. 2(1): 00013.
10. Infection control in Medicine with Relevance to Mitophagy and Organ Survival. Acta Scientific Pharmaceutical Sciences. 3.11, 2019.
11. Biotherapy and the Immune System in Ageing Science. Acta Scientific Nutritional Health 2.4 (2018): 29-31. 12. Sirtuin 1, a Diagnostic Protein Marker and its Relevance to Chronic Disease and Therapeutic Drug Interventions. EC Pharmacology and Toxicology 6.4 (2018): 209-215.
For MMSE (Mini Mental State Exam), illiterate people are unable to answer questions requiring them to read and follow instructions, such as the question asking them to follow instructions to close their eyes. Individuals who are paralysed are also unable to complete the tasks of taking the paper in their right hand, folding it in half and putting it on the floor. For such cases, how should we interpret their results? Should those items be excluded entirely (i.e their score is upon 29 instead of 30) and be scaled to be upon 30?
I'm a PhD student wondering how to approach this topic.
autophagic activity suppression by Rubicon is a signature of aging.
how many time it takes in the suppression of autophagic activity by Rubicon?
When Rubicon functions in neurons?
How Rubicon functions in neurons?
There are several excellent instruments and scales many of which have been validated numerous times. I am going through an exercise in comparing and contrasting the benefits and constraints of each (e.g. Revised Kogan's Attitudes Toward Old People scale (RKATOP), Age Group Evaluation and Description Inventory (AGED Inventory), Sarkisian's Expectations regarding Aging survey) to arrive at my own conclusions, but would also like the input of other researchers.
I am studying the cerebral aging in non - human primates, Marmost monkies. The study is conducted on anatomical MRI T1-weighted images. We aim to study the decline of brain and cortical volumes in normal aging.
However, due to the difficulty of extracting (segmenting) some cortical subregions, we would like to rather map the volumetric differences in these regions over years (due to aging / possible atrophy) rather than dileneating and extracting ROIs.
I would appreciate if some one could suggest a method (reference) or an algorithm to start with.
The phrase "geriatric profanity disorder", together with its initialization "GPD", has become somewhat of a meme, being mentioned in TV shows like the Simpsons and receiving an entry in the Urban Dictionary. Is it an actual recognized condition or area of research (perhaps under another name)?
We are planning to assess elderly health and sociodemographic profile telephonically on the Indian population. Any suggestion about methodology and validated scale.
Genomic medicine treatment of diabetics is critical in the current global diabetes epidemic to prevent the expected diabetes pandemic predicted to occur by the year 2035. The major concern with Type 3 diabetes in the global population is related to a defective SCN with relevance to uncontrolled peripheral glucose levels and endocrine autoimmune disease. Appetite regulation and genomic medicine are critical to Sirt 1’s regulation of the MHC genes with relevance to maintenance of immune recognition and endocrine hormone treatment of mitophagy. In the developing world the major concern for a diabetes pandemic is mitophagy and will require diets with Sirt 1 activators to prevent Type 3 diabetes, endocrine autoimmunity and mitochondrial disease.
1. Martins IJ. Genomic Medicine and Endocrine Autoimmunity as Key to Mitochondrial Disease. Glob J Endocrinol Metab .2(2). GJEM.000534.2018
2. Martins IJ. Biotherapy and the Immune System in Ageing Science. Acta Scientific Nutritional Health 2.4 (2018): 29-31.
3. Martins IJ. Appetite Control and Biotherapy in the Management of Autoimmune Induced Global Chronic Diseases. J Clin Immunol Res. 2018; 2(1): 1-4.
4. Martins IJ. Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases. Diseases. 2018, 6;39:1-5.
5. Martins IJ. Autoimmune disease and mitochondrial dysfunction in chronic diseases. Res Chron Dis (2017) 1(1).
6. Martins IJ. Regulation of Core Body Temperature and the Immune System Determines Species Longevity. Curr Updates Gerontol. (2017) 1: 6.1
7. Martins IJ. Anti-Aging Gene linked to Appetite Regulation Determines Longevity in Humans and Animals. International Journal of Aging Research. 2018,1(6): 1-4.
8. Martins IJ. Genomic medicine and acute cardiovascular disease progression in diabetes. Res Chron Dis (2018) 2(1), 001–003.
9. Martins IJ. Genomic Medicine and Acute Cardiovascular Disease Progression in Diabetes. International Journal of Medical Studies. 2018;3(1): 124-130.
10. Martins IJ. Electroconvulsive Therapy and Heat Shock Gene Inactivation in Neurodegenerative Diseases. Ann Neurodegener Dis. 2018, 3(1): 1028.
11. Martins, I.J. (2018) Indian Spices and Biotherapeutics in Health
and Chronic Disease. Health, 10, 374-380. WITH AND WITHOUT INDIAN SPICES
Besides the previously discovered circadian clock (the 24-hour timekeeper) is there another master regulator clock controlling aging and other time scheduled events of life, such as fetal development and puberty (and ultimately over-watching the whole cycle of aging) which are precisely time-dependent, by keeping the track of solar “years” passed?
Aging process is part of zeolite synthesis. What is the importance of the step? May you suggest whether I should aging before or after hydrothermal?
We welcome MPH students in Sweden and outside Sweden using SAGE, SAGE-INDEPTH, SAGE-HIV WOPS, or any data sets to engage on this project - add yourself as a contributor, and contribute to the discussions here. Use this as a portal to ask questions, raise issues with data and analyses, and engage with other data users.
A Culture–Brain Link: Negative Age Stereotypes Predict Alzheimer’s Disease Biomarkers.Levy, Becca R.; Ferrucci, Luigi; Zonderman, Alan B.; Slade, Martin D.; Troncoso, Juan; Resnick, Susan M.
Psychology and Aging, Dec 7 , 2015, No Pagination Specified. http://dx.doi.org/10.1037/pag0000062
Although negative age stereotypes have been found to predict adverse outcomes among older individuals, it was unknown whether the influence of stereotypes extends to brain changes associated with Alzheimer’s disease. To consider this possibility, we drew on dementia-free participants, in the Baltimore Longitudinal Study of Aging, whose age stereotypes were assessed decades before yearly magnetic resonance images and brain autopsies were performed. Those holding more-negative age stereotypes earlier in life had significantly steeper hippocampal-volume loss and significantly greater accumulation of neurofibrillary tangles and amyloid plaques, adjusting for relevant covariates. These findings suggest a new pathway to identifying mechanisms and potential interventions related to the pathology of Alzheimer’s disease. (PsycINFO Database Record (c) 2015 APA, all rights reserved)
I am trying to locate surveys/data sets that provide information about ageing and health in a number of countries in the Asian region - including, for example, the 2014 Myanmar Ageing Study, 2011 Viet Nam National Aging Study and SAGE India Waves 0-2; however, I cannot locate studies in Lao PDR, Malaysia, Nepal, and the Philippines. Any connections to colleagues/surveys and advice would be welcome.
I am starting a research that investigates the correlation of the reasons for migration befote to move in retirement and the well-being after the change? Could anyone help me with instruments and literature review.
Lucia Franca is professor at The Graduate Program in Psychology at Universidade Salgado de Oliveira - Rio de Janeiro - Brazil
Hi Joseph, I am a Neuroscientist and have been using deprenyl as you prescribed for 20 years now and at 78 have no diabetes or heart problems and weigh 170 lbs. I still ride my dual purpose motorcycle. I have lost erectile function and wear hearing aids. What progress have you made in the last 20 years that could benefit me? Thank you for your very important work and contributions! http://www2.hawaii.edu/~bemorton
I am interested to carryout ageing research using mice as the tool. We have genetic knockouts for the protein of interest. I am curious to know if there are any ways (chemically or pharmacologically) reported methods to accelerate the ageing processes?
Thanks for your comments.
Any articles or research in progress related to the use of wearable technology to assist early suffers of Dementia?
What devices? Any interesting case studies/scenarios?
Can anyone recommend a book or other useful resources about images of aging in advertising?
Dear friends, I read an article recently published (Danielle M. Townsley, Bogdan Dumitriu, Delong Liu, Angélique Biancotto, Barbara Weinstein, Christina Chen, Nathan Hardy, Andrew D. Mihalek, Shilpa Lingala, Yun Ju Kim, Jianhua Yao, Elizabeth Jones, Bernadette R. Gochuico, Theo Heller, Colin O. Wu, Rodrigo T. Calado, Phillip Scheinberg, Neal S. Young. Danazol Treatment for Telomere Diseases. New England Journal of Medicine, 2016; 374 (20): 1922 DOI: 10.1056/NEJMoa1515319). It is hypothesized that androgen can increase Telomere length and indirect measure for lifespan, though, since long we know that females often live a longer life and demographic population data also reveal the same.
I am unable to understand the contradiction, do anyone can explain.
Anyone aware of or use a specific workload setting for older populations performing a Wingate? Age 65 and above
We are running a study where we measure grip strength to older patients in acute medical wards to flag up those with low levels who might be at risk of poor healthcare outcomes. We know that grip strength vary according to age, gender, and dominant hand, but I am not aware that there is any research on whether the grip strength of a patient vary when it is being tested before and after meals. It would be helpful if anyone can share their experiences or refer me to any useful references.
We are doing a research on successful aging and I need to assess the prevalence of successful elderly people. I will appreciate some tips on this...
has anyone any idea what happened to Alagebrium (ALT-711)? It seemed to be very promissing drug candidate to retard some features of aging, but it dissapeared suddenly from experimenal works, the internet etc. etc. few years ago. It still wonders me...
I will look at to the effect of aging on learning and memory in rat (using Morris Water Maze test).
The rat will be performed the testing when they reach the age of 8, 12, 16, 20 months.
Is it possible to use the same rat for testing?
The previous testing (at 8 month age) will interfere the result of the later testing (at 12 or 16, 20 month age) , or not?
or I should separate the rat into 4 group?
What is the minimum of time interval between the two testing (in case of Morris water maze test) can be performed?
I am interested in measuring functional decline in elderly people living in the community.
Keen to hear if anyone has compared how well Horvaths' DNA methylation-based ‘epigenetic clock’ relates to Blackburn's telomere length, as an assessment of the ageing process in different cultures/peoples.
Is it the extraction as same as other herbal compound extraction?
I would appreciate key reviews/summaries and published/unpublished manuscripts - looking at for example, ageing, expectations, population growth, time-to-death versus inappropriate use of expensive technology, health care practices, etc.
For example, see
Atella, et al. The effect of age and time to death on primary care costs: the Italian experience. Soc Sci Med. 2014;114:10-7.
Blakely et al. Health system costs by sex, age and proximity to death, and implications for estimation of future expenditure. NZ Med J. 2014;127(1393):12-25.
Age-related loss of complexity in physiological, neural, cognitive and motor systems is a widely accepted hypothesis in the aging literature (see Lipsitz & Goldberger, 1992 for an introduction).
According to WHO, Active ageing is the process of optimizing opportunities for health, participation and security in order to enhance quality of life as people age. It applies to both individuals and population groups.
With the population ageing world wide, Its necessary to carry out different activites to make active ageing to our senior citizens. From this active ageing it will indirectly save the health expenses and other social support related expenses of the family, society, community and of Nations. While sharing the Policy and Action program carried out in your country or region or community people from developed country or other region can also replicate the program which will be useful for the well being of aging society.
I look forward to get lots of theoretical or empirical study results as well as policy related materis will be shared in this forum related with active ageing. Thank you every one for your kind contribution.
Will be used pre and post intervention on elderly residents in a retirement home
In studying health of older people, what are common confounding variables, and what are the implications on study design?
Working on a research project called Dementia and Imagination
Malaysia is just ONE of the countries with an aging population; there are other such countries. "Malaysia's population is ageing at a faster rate than many may have realised. The average life expectancy for women and men in Malaysia is 76 and 73 years, respectively."
At the same time, many young Malaysians are working in distant places: Australia, UK, Europe, and the ASEAN region. What must be put in place to care for aging relatives in a community, when children, the primary care givers, work far from home?
And, how can we ensure that all older adults receive the care and dignity they need to enhance quality of life in old age?
In the field of media education / media literacy education, most of the research and practices are aimed at children, young people or their parents? Does anyone know of research or practical work that focuses on media education of older people, i.e. people over 60 years of age?
What are the most indicated tests for it assessed cognitive function in the elderly? In particular, measures to quantify the following cognitive domains: memory, attention, language, visuospatial ability, and executive function.
Any suggestions for references?
I have data showing highly significant differences between younger (20-34) and older (60-74) adults in the relative proportion of thoracic breathing at rest, sitting. Older adults have more thoracic breathing than younger adults.
Is anyone aware of research findings concerning this aspect of breathing (anything that could be relevant to understand/explain my results)?
Is there is any software which can tell the biological age from face?
I'm looking for the research verifying if the training-induced changes in cognitive task performance are connected with the changes in human brain, in terms of compensatory patterns, as PASA or HAROLD (or some other).
There are, as I understand it, some indications that mindfulness training may improve executive functioning in certain populations that show deficits (e.g. ADHD). Is there any evidence of improvements from mindfulness-based training on cognitive functions in normal elderly/elderly with mild cognitive impairment?
I am interested to do my higher studies to find out best skull morphology to estimate the human age which could be helpful in forensic studies.
I would like to use CBCT or CT images of living patients.
There are no such studies performed in Sri Lankan population.
Experts' views are well come...
Hi, I want to find out change in concentration of six different proteins due aging in muscle tissue. I am performing western blot right now. Is there another technique available to get accurate protein concentration? I don't have purified proteins to use as standers so can't perform ELISA.
"Socio-demographic factors" may in fact be genetic for two reasons. 1) Social status is largely transmitted within a family, and familial transmission is in part an environnemental sensu lato, in part genetic. 2) Geographical origin, particularly in Southern Italy, is noted as a "socio-demographic factor"; it may, in fact, act through a genetic founder effect, and the origin in Calabria of the largest documented Alzheimer kindred not be a coincidence (BRUNI A.C, MONTESI M.P., SALMON D., GEI G., PERRE J., EL HACHIMI K.H., FONCIN J.-F. : Alzheimer's disease: a model from the quantitative study of a large kindred. J. Geriatric Psychiatry and Neurology 1992 5 126-131).
We are trying to measure the telomere length with respect to this SCG but the Ct values are coming very high, from 21 to 31. We are following Cawthon method and tried different Tm for amplification. Didn't help much. We are using Sybr select master mix and running in QuantStudio 12K Flex from ABI. If anybody can help. Thanks.
Relatively little is known about the association between ageing and health care costs in middle- and low-income countries - whereas, in high income countries, available data does not yet point to a clear answer - with income elasticity and patient expectations, time to death, the type of service (inpatient or outpatient), and expensive technology, all possibly contributing more to increased spending than ageing populations.
See for example, Asia in the ageing century: Part III - Health care. www.cepar.edu.au/media/113850/asia_in_the_ageing_century_-_part_iii_-_healthcare.pdf
Any relevant and recent (last 5 years) analyses, published or in the grey literature, would be appreciated.
Neuropsychiatric symptoms (NPS) in dementia have been described since Alois Alzheimer’s index case of Auguste D, who presented initially with emotional distress and delusions of infidelity. NPS are common in dementia with prevalence rates of up to 97%. Over time, NPS have become understood to becore symptoms of dementiaand are included in the most recent criteria for all cause dementia. NPS in dementia are associated with faster cognitive decline and acceleratedprogression to severe dementia or death, higher rates of institutionalization, greater functional impairment, greater caregiver stress, worse quality of life and higher burden of neuropathological markers of dementia. NPS are also present in Mild Cognitive Impairment (MCI) with a prevalence of 17-55% and are also associated with poorer outcomes, increased neuropathological burden and faster conversion to dementia, compared to patients without NPS. Evidence now suggests that NPSin the absence of cognitive symptoms may manifest as the initial symptoms of neurodegenerative disease. 28% of dementia cases are initially given psychiatric diagnoses and they present with psychiatric symptoms such as apathy, anxiety, depression or mania. However, there is no systematic method of diagnosing these early NPS and much further work in this area is required.
I am doing research on geriatric rehabilitation
Nutrition and resistance exercise are two safe interventions for sarcopenia management. What are the new implications toward this field?
We are looking for large cohort data analysis expert. We are a part of aging related research and are looking for a statistician.
To my knowledge the mini-mental state examination (MMSE) is most commonly administered within memory clinics. Could anyone tell me who also administers this measure (or similar general measures) in their area please? For instance, I am interested in knowing if anyone is aware of other professionals who ‘screen’ patients in primary care prior to referral to a memory team.
Researchers from the University of Granada and Jaén (Spain) are looking for researchers from other parts of Europe that are planning to develop a proposal in a European project (HORIZON 2020) in the field of aging processes (successful aging, cognitive decline, cognitive training).
We would be interested in joining in such a proposal as partners of the Consortium. We have wide experience in these areas. If someone needs more information about my group and interests, please note below.
When studying some metabolic parameters in elderly people, it seems difficult to distinguish which ones are caused by aging per se or by age-related diseases. In particular, circulating IL-6 is known to increase with age but is it a relevant biomarker of aging since it is also elevated in metabolic diseases such as obesity or atherosclerosis. Then, is there a very specific biomarker of aging?
How can we characterize healthy elderly? For the recruitment of such cohort, do we exclude all kind of diseases or can we tolerate some?
For example, in India there is a growing demand of better places, support, and homes for aged.
What is being done for the elderly and aging population in your corner of the globe?
A friend of mine from India feels called to work the rest of his life on the project of creating in his homeland better facilities, structures, and support systems, institutions, and networks for the aging millions in India. The need is particularly strong historically there for widows, but others who do not wish to move across the country to relatives need help, too. I told him that Denmark and other countries in Europe have great continuing education and training programs for aged. Such focus on adult education and support in more developed lands is a resource for developing ones.
I'm looking for good references on measuring sirtuin levels in aging. I'm also interested in the best method of sirtuin levels analysis in human plasma. Any suggestions?
I'm interested in knowing how the elderly cope with the present and how to increase resilience with climatic stressors.
As part of an effort to explore the epigenetics of ageing, we have collected matched saliva and peripheral blood via fingerprick. Understanding patterns across different tissues may be similar, the literature on the equivalence of DNA from saliva and DBS is sparse, and would appreciate any unpublished/published data/results.
Is it a helpful method to use with older people? Are there any issues to bare in mind? I am specifically thinking about indoors (home) walking interviews and if anyone had any similar experience?
1. About the term of " cardiac sacropenia", what is current common sense about the association of sacropenia and aging heart (or other term such as cardiac sacropenia?)
2. Another question is about asian population, What is any reference about appendicular skeletal muscle mass <2 SD below the mean of a young
reference population ?
Obsolescence means "Study of aging". Counting age of citations and references and relating to weeding out policy in the libraries and depending on the older literature by scientists.