Zuzana Ruberová's research while affiliated with University of Chemistry and Technology, Prague and other places

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Publications (2)

Functionalized hydrogel microparticles prepared by microfluidics and their interaction with tumour marker carbonic anhydrase IX
Article
  • Aug 2020
Microfluidics allows to accurately control the synthesis of microparticles for specific applications, where size and morphology play an important role. In this work, we introduce microfluidic chip design with dedicated extraction and gelation sections allowing to prepare hydrogel particles in size range of a red blood cell. The influence of the ext...
Microfluidic fabrication of composite hydrogel microparticles in the size range of blood cells
Article
  • Jan 2016
The fabrication of alginate hydrogel microparticles with embedded liposomes and magnetic nanoparticles for radiofrequency controlled release of encapsulated chemical cargo was considered. An extractive gelation process was implemented in a microfluidic device, which enabled the production of uniform composite microparticles of dimensions comparable...

Citations

... This enables a considerable reduction of the ecological impact of research and development, and potentially increases the rate of production of new formulations. Drop microreactors have been successfully used for activities including the measurement of kinetic constants of chemical and biochemical reactions [2][3][4], drug-protein association constants [5], cell screening [6][7][8], synthesis of nanoparticles [9][10][11] and hydrogel particles [12][13][14]. ...
Reference: Effect of Surfactant Dynamics on Flow Patterns Inside Drops Moving in Rectangular Microfluidic Channels
... Therefore, dissolving microdroplets show great promise in their applicability as miniature reactors for solvent-diffusion-driven crystallization to produce protein crystals or solid drug dosages [30,31]. Furthermore, diffusion of water into the surrounding oil phase on a microfluidic chip has been used to create hydrogel microparticles with a homogeneous and modifiable size distribution [32]. ...
Reference: Characterization of the Dissolution of Water Microdroplets in Oil