Zhixiang Su's research while affiliated with Capital Medical University and other places

Publications (3)

Article
Objective: There is no medical treatment proven to limit abdominal aortic aneurysm (AAA) progression. This systematic review aimed to summarise available trial evidence on the efficacy of pharmacotherapy in limiting AAA growth and AAA-related events. Methods: A systematic literature search was performed to examine the efficacy of pharmacotherapy...
Article
Full-text available
Objective This study identified underlying genetic molecules associated with histologically unstable carotid atherosclerotic plaques through bioinformatics analysis that may be potential biomarkers and therapeutic targets. Methods Three transcriptome datasets (GSE41571, GSE120521 and E-MTAB-2055) and one non-coding RNA dataset (GSE111794) that met...
Article
Objective The study aimed to assess the gene expression profile of biopsies obtained from the neck of human abdominal aortic aneurysm (AAA) and the main site of AAA dilatation and to investigate the molecular mechanism underlying the development of AAA. Methods The microarray profile of GSE47472 and GSE57691 were obtained from the Gene Expression...

Citations

... Some novel biomarkers for NOA were also screened. Ribosomal Protein S4 X-Linked (RPS4X) was essential for the formation of cytoplasmic ribosomes and participated in the initiation and progression of multiple diseases [29][30][31]. RPS4X acted as the strongest predictor in the random forest model with the highest Mean Decrease Accuracy and Mean Decrease Gini. ROCs also indicated that RPS4X was a promising diagnosis biomarker for NOA both in the training (AUC = 0.932) and external validation (AUC = 0.920) cohorts. ...