Zhiping Li's research while affiliated with First Affiliated Hospital of China Medical University and other places

Publications (13)

Article
Full-text available
Background: The role and expression level change in circ_TNPO1 (hsa_circ_0072951) in atherosclerosis (AS) and VSMC dysfunction remain unknown. In this study, we try to explore the effects of circ_TNPO1 on oxidized low-density lipoprotein (ox-LDL)-induced human vascular smooth muscle cell (VSMC) excessive proliferation and migration, and the potent...
Article
Autophagy plays a critical role in cardiac hypoxia/reoxygenation (H/R). Studies indicated that the phosphatase and tensin homolog (PTEN) influences level of autophagy. This study aims to explore the role of PTEN mediating a specific autophagy, mitophagy, in cardiac H/R injury. H9c2 cells were cultured and suffered hypoxia and reoxygenation treatmen...
Article
Transthoracic device closure (TTDC) and surgical repair with right infra-axillary thoracotomy (SRRIAT) are two main alternative minimally invasive approaches for restrictive perimembranous ventricular septal defect (VSD); however, few studies have compared them with each other in terms of effectiveness and cost. Patients with perimembranous VSD und...
Article
We report a case of a 14-year-old female with abnormally high takeoff of the right coronary artery (RCA) that was associated with a ventricular septal defect, right aortic arch, and bridging bronchus. During surgery, an exceptionally high takeoff of the RCA was discovered. Postoperative computed tomography confirmed the presence of the associated r...
Article
Hypoxia can induce autophagy, which plays an important role in cardioprotection. The present study tested the hypothesis that patients with congenital heart disease living at a high altitude could resist ischemia-reperfusion injury better than those at a low altitude, through elevated basal autophagy by chronic hypoxia. Twelve Tibetan patients resi...
Article
We investigated risk factors for acute kidney injury (AKI) in patients undergoing same admission coronary angiography (CAG) and valve replacement. Among 283 consecutive patients undergoing valve surgery between October 2010 and July 2012, 71 patients with same admission preoperative CAG were included in the study. Predictors of AKI were identified...
Article
Full-text available
Reports of the association between the time interval from coronary angiography (CAG) to cardiac surgery and risk of postoperative acute kidney injury (AKI) are controversial. We attempted to examine this association by conducting a meta-analysis. We searched the Pubmed, MEDLINE, EMBASE, Web of Science databases, and the Cochrane Library from Januar...
Article
A 68-year-old man was transferred emergently to our department because of multichamber intracardiac thrombosis. Enhanced computed tomography revealed multichamber thrombosis in the right atrial appendage, right ventricular outlet tract, and left atrial appendage, with localized aneurysm of a much enlarged right ventricle. He underwent thrombectomy...
Article
We report a case of recurrent hemoptysis due to an occult congenital fistula between the descending aorta and the left pulmonary vein in a 25-year-old female patient. The anomaly was confirmed by contrast-enhanced CT scan and angiography. No abnormality was noted in the bronchia and pulmonary arteries. The patient was successfully managed by simple...
Article
Full-text available
Locally advanced lung cancer includes IIIA and IIIB lung cancer that tumors are localized within the chest and with no clinic and pathologic distal metastasis. In this study the results of extended resection of a portion of heart or great vessels with cardiopulmonary bypass was summarized in the treatment of locally advanced lung cancer. Lobectomy...
Article
To assess the effects of exogenous p73 gene on chemosensitivity of wild-type p53 human lung adenocarcinoma cell A549 to cisplatin (DDP) and adriamycin (ADM). Recombinant eukaryotic expression vector pcDNA3 containing full-length human wild-type p73α cDNA or p53 cDNA was transfected into A549 cells which had wtp53 by lipofectamine-mediated gene tran...
Article
To investigate the expression of p63 gene and its significance in non-small cell lung cancer (NSCLC) and pulmonary benign disease tissues. p63 gene mRNA expression (TAp63 and ΔNp63) was detected in 40 NSCLC and 10 pulmonary benign disease tissues by RT-PCR (reverse transcriptase-PCR) technique, and immunohistochemical method was used to observe p63...

Citations

... Inhibition of PTEN could promote endothelial survival via activating the AMPK-CREB-Mfn2mitophagy signaling pathway providing a beneficial influence on mitochondrial homeostasis, cellular survival, and endothelial migration (Li et al. 2020). A recent study by W Tang et al. concluded that inhibition of PTEN function induced by bv (phen)-suppressed PINK1/Parkin-mediated mitophagy, which resulted in an increased apoptosis and release of mitochondrial Cytochrome C in H/R-injured H9c2 cells (Tang et al. 2019). Another study has also suggested that inflammation-induced PTEN downregulation resulted in TLR4-JNK-Bnip3-mitophagy pathway activation, which eventually amplified the cellular death signals in nasal epithelial cells (Li et al. 2018). ...
... The literature search yielded 5457 published articles. Further screening and exclusion reduced these to 15 articles (including 4381 patients) which were used for the statistical analysis [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]. Among them, three papers [23,26,28] were 3-arm studies comparing the efficacy of transcatheter closure, perventricular closure, and surgery, and the rest were direct comparisons. ...
... Other cardiac anomalies are commoner in patients with a rightsided aortic arch. Focused echocardiography and coronary angiography are required due to the association with septal defects and coronary anomalies (high take off of the right coronary artery which is very relevant in the case of Type A dissection) [2,39]. ...
... Conversely, recent evidence has shown benefits from high-altitude environments on cardiovascular disease [25,26]. Interestingly, postoperative outcomes after cardiac surgery among patients living at high altitude have been shown to be better than those among patients living at low altitude [27,28]. In animal studies, chronic and/or intermittent exposure to a hypobaric hypoxic environment can attenuate ischemiainduced arrhythmias, improve the efficiency of ATP generation [17], decrease age-related remodeling [18], and bring about improvements in myocardial capillaries [29], cardiac function, and mitochondrial function [30,31]. ...
... 1,2 Brown and colleagues 3 showed that in selected patients, same-day CA and valve surgery had little effect on postoperative renal dysfunction and hospital mortality. Hu and colleagues 4 and Greason and colleagues 5 reported safe same-day CA and aortic valve replacement, but no evaluation was performed on the risks of hospital mortality and acute kidney injury (AKI) according to time after CA in patients with renal failure. In contrast, other studies have shown that surgery performed within 24 h or 5 days after CA increased the risks of AKI and hospital mortality. ...
... Acute kidney injury is reported to occur in up to 30% of patients after cardiac surgery with CPB, whereas CIN after CAG has been reported to occur in 10% of patients with normal renal function but in 25% of patients with pre-existing renal failure [31]. Contrast-induced AKI is defined as the onset of acute renal failure within 2-7 days after administration of iodinated CM (most common-ly after CAG and percutaneous coronary intervention), and it is one of the leading causes of acute renal failure during hospital stay [32]. ...
... Right ventricular (RV) thrombi may develop as a result of blood stagnation in patients with dilated cardiomyopathy [1][2][3] and arrhythmogenic RV cardiomyopathy [4], or in those with myocardial infarction that involves RV wall [5]. They have not been reported in patients with hypertrophic cardiomyopathy (HCM), although left ventricular (LV) apical thrombus is a relatively well-recognized complication of HCM with LV apical aneurysm. ...
... The p73 protein can activate upstream transcriptional regulation of p21 and p27, resulting in cell cycle arrest in G2 (43)(44)(45). In human lung adenocarcinoma, p73 overexpression can enhance chemosensitivity by apoptosis induction (46,47). Namwat et al (16), reported the association between downregulation of TAp73 mRNA and 5-FU-resistant CCA cell lines. ...
... Contrariwise, TAp63 expression is associated with the induction of senescence and the inhibition of cell proliferation (Guo et al., 2009a;Wang et al., 2005). Absence or downregulation of that isoform can induce oncogenesis and metastasis, as studied in several cancers (Guo et al., 2004;Guo et al., 2009a;Lo Iacono et al., 2011;Park et al., 2000). ...
... About half of the hospitalized patients affected by swine-origin influenza virus (S-OIV) have had underlying conditions such as asthma and other lung diseases, diabetes, morbid obesity, auto-immune disorders, immunosuppressive therapies, neurological or cardiovascular disorders or pregnancy (febrile respiratory infection ) [1] [2]. It is fairly clear that the invasion of influenza virus into the respiratory system might give rise to pneumonia. ...