Zararna Louise Nelson-Moon's research while affiliated with WWF United Kingdom and other places

Publications (8)

Article
The aim of this article was to encourage good practice in the statistical analyses of orthodontic research data. Our objective was to highlight the statistical problems caused by mathematical coupling (MC) in correlation and regression analyses. These statistical problems are among the most common pitfalls in orthodontic research when exploring ass...
Thesis
Masseter muscle structure and function have been implicated in the development of extremes of vertical facial form (VFF), Long Face Syndrome (LFS) and Short Face Syndrome (SFS). The overall aims of this project were to investigate the relationship between masseter muscle structure and VFF and to establish whether certain structural features related...
Article
Full-text available
To evaluate the potential for machine learning techniques to identify objective criteria for classifying vertical facial deformity. 19 parameters were determined from 131 lateral skull radiographs. Classifications were induced from raw data with simple visualisation, C5.0 and Kohonen feature maps; and using a Point Distribution Model (PDM) of shape...
Article
Changes in masticatory muscle structure and function are either developmental, as seen in anomalies of facial form, or adaptive, as seen during procedures such as orthognathic surgery and functional-appliance orthodontic therapy. Remodelling of muscle extracellular matrix is pivotal in these processes. This turnover is mediated via members of the f...

Citations

... There is some evidence to support this as indicated by a study which compared the presence of developmental myosin heavy chains in relation to the number of occlusal contacts seen in a group of patients with a variety of both normal and abnormal facial form. 6 There is an inverse relationship present such that the greater the number of occlusal contacts, the lower the presence of developmental myosin heavy chains (Figure 3). One explanation for this could be that in patients with a poor occlusion and few occlusal contacts, the muscles are repeatedly undergoing micro-trauma, and are regenerating and adapting in order to try to produce a more efficient functioning muscle-occlusal system. ...
... Rubber dam use has been proposed to minimize the risk of moisture contamination during BR placement but its use did not reduce bond failure rates. 48 The enamel surface requires thorough cleaning, with some advocating sandblasting. 43 ...
... The muscles of mastication of which the masseter is extensively studied, also possess a third type of fibres termed the intermediate fibres. Moon, 2001). The MHC expression in LFS corresponds well with fibre distribution in these patients. ...
... Metalloproteinases are proteins with enzymatic activity that play a key role in selective proteolysis of ECM components Changes in the basement membrane collagens were accompanied by generally similar changes in the gelatinases MMP2 and MMP9 [24,25]. Metalloproteinases are proteins with enzymatic activity that play a key role in selective proteolysis of ECM components [26,27]. MMP2 and MMP9 are the typical MMPs of skeletal muscle and are involved in the degradation of collagen IV [28]. ...
... Nowadays, machine learning is increasingly being used in the medical field ranging from medical image processing and the diagnosis of specific diseases to the broader tasks of decision support and outcome prediction (Hammond et al., 2001;Rubin et al., 2017;Torlay et al., 2017;Lee et al., 2018;Livne et al., 2018;Vaquerizo-Villar et al., 2018;Wang et al., 2018;Chang et al., 2019;Dinh et al., 2019;Xu et al., 2019;Suhail et al., 2020;Verma et al., 2020;You et al., 2020). However, machine learning methods are rarely applied to evaluate craniodentofacial morphological harmony after orthodontic treatment. ...
... There may be factors involved in the clinical decision to remove either the four first premolar teeth or the four second premolar teeth that were not be measured and, therefore, not controlled in this study. Also, the pre-treatment value of an outcome measure can have an effect on the amount of change over time of that outcome measure [20,21]. ...