Zafer Özmen’s research while affiliated with Tokat Gaziosmanpaşa Üniversitesi and other places

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Publications (20)


Evaluation of abdominal vascular structures by multidetector computed tomography in Crimean–Congo hemorrhagic fever patientsKırım Kongo kanamalı ateşi hastalarında abdominal vasküler yapıların çokkesitli bilgisayarlı tomografi ile değerlendirilmesi
  • Article
  • Full-text available

May 2023

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13 Reads

Journal of Health Sciences and Medicine

Zafer ÖZMEN

Aim: This study aims to determine whether Crimean–Congo Hemorrhagic Fever (CCHF) has effects on abdominal vascular structures. Material and Method: The study group included 35 patients diagnosed with CCHF. The control group included 35 patients with symptoms such as dyspepsia, pelvic pain, and abdominal pain who underwent multidetector computed tomography (MDCT) and whose MDCT examinations were reported as completely normal. This is a retrospective study and patients admitted to the hospital between May 2016 and April 2022 were included in the study. The patient group and control group were compared in terms of liver size, splenic size, and portal vein (PV), hepatic artery (HA), splenic vein (SV), splenic artery (SA), superior mesenteric vein (SMV) and superior mesenteric artery (SMA) diameters. Results: The liver size, splenic size, and PV, HA, and SA diameters in the patient group were significantly higher than those in the control group (p0.05). Conclusion: Our study shows that abdominal vascular structures are affected in CCHF patients.

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Diffusion MRI in Intracranial Hypertension: Quantitative Assessment

August 2022

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1 Read

Purpose Intracranial hypertension (IH) is a neurological disease that is characterized by increased intracranial pressure. Idiopathic intracranial hypertension (IIH) is characterized by an increase in intracranial pressure without an underlying neuroradiological cause (1-3). The IH that is associated with a reason such as a mass, hydrocephalus, or drug use, is referred to as secondary intracranial hypertension (SIH). We aimed to detect determine whether the increased intracranial pressure causes a change in the diffusion values of brain in the diffusion MRI images. Methods The study includes 24 consecutive patients that were diagnosed with IIH and 18 consecutive patients that were diagnosed with secondary intracranial hypertension (SIH). The control group included 24 patients. Measurement of apparent diffusion coefficient (ADC) was performed using DWI sections obtained from subcortical white matter and the cortex of the frontal lobe in the basal ganglia plane, caudate nucleus head, thalamus, the posterior leg of the internal capsule, corpus callosum splenium; in the centrum semiovale plane, from the central white matter region. with 1.5T MRI using b=500s/mm2 and b=1000s/mm2 values both in patients and control groups. Mean ADC values were compared between IIH, SIH patients and control groups. Results The ADC values from the head of the caudate nucleus and the cortex were significantly higher in the IIH group, compared to the control group. When the ADC values of the SIH and control groups were compared, it was found that some of the ADC measurements (subcortical white matter, cortex and semioval center) were significantly different. The comparison of the IIH and the SIH groups revealed that the ADC measurements central white matter in the centrum semiovale, the subcortical white matter and the posterior leg of the internal capsule were significantly different. Conclusıons We have found increased diffusion IIH and SIH patients, which supports the development of brain edema. Even though the mechanism of the brain edema in IIH are not entirely clear, it is thought that the mechanism is different from the brain edema caused by a mass or a sinus thrombosis.


A new dıagnostic tool for assessment of pelvıc dysfunction ın MR defecography

May 2022

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1 Read

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1 Citation

Background Pelvic floor dysfunction is characterized by incomplete fecal defecation, affecting quality of life in a negative way. Magnetic resonance defecography (MRD) is a useful examination that is ionizing radiation-free and easily reproducible, and which provides anatomical and functional details that are obtainable through multiplanar and dynamic examinations. We aimed to detect pathology using MRD in patients with suspected pelvic floor dysfunction and determine its cause. Methods MRD was performed in 79 individuals. Dynamic images were obtained at rest, straining, and during defecation. Pelvic hiatus mediolateral diameters were compared between groups. Results Defecation phase provided significantly more accurate results than the straining phase for determining the existence and severity of pathology. Conclusıons The defecation phase is the most accurate phase for identifying the existence and severity of pathology. As the pelvic hiatus mediolateral diameter is thought to be an important factor in triggering pelvic dysfunction.



Abdominal US Findings of Crimean-Congo Hemorrhagic Fever

June 2020

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12 Reads

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2 Citations

Journal of Contemporary Medicine

Introduction: Crimean-Congo hemorrhagic fever (CCHF) is one of the deadly diseases, clinically causing viral hemorrhagic fever outbreaks. It is especially transmitted through tick bite and body secretions and accepted as an indigenous disease in certain regions in the world and in our country. Many of the organs, especially the lungs, are affected by this disease. However, current studies are not sufficiently relate the disease and abdominal organ involvement. Therefore, we aim to discuss the ultrasonography (US) findings of the CCHF disease in the context of the literature. Material and Method: The retrospective analysis of the hospital records of 283 patients, who were serologically diagnosed as CCHF between 2012-2016 was performed. Abdominal ultrasonography examination revealed that, 20 of those patients had findings in the womb. US findings of these 20 patients were analyzed. Results Nine patients (45%) were male, and 11 patients (55%) were female. The most common findings of abdominal US examinations were; the hepatomegalia and the intra-abdominal free fluid. Gallbladder wall thickening and splenomegalia were also commonly found in these patients. Periportal hyperechogenicity, intramuscular hemorrhage, colon wall thickening, sludge in gallbladder, renal hyperechogenicity, renal ectasia and ureter dilatation were rarely observed. Conclusion Our study is among the exceptional studies on the analysis of abdominal US findings of CCHF. The most commonly observed findings in our patients were the hepatomegalia and the intra-abdominal free fluid. Intra-abdominal findings of the disease were extremely variable. This study will shed light to the future comprehensive studies.


Ultrasound imaging of the diaphragm
Comparison of the diaphragm thickness at end-expirium and end-inspirium according to the apnea subtype. Bold p values denote significance. End-expirium (right/left). Normal vs. mild OSAS: p = 0.681/p = 0.353. Normal vs. moderate OSAS: p = 0.699/p = 0.086. Normal vs. severe OSAS: p = 0.032/p = 0.012. Normal vs. OSAS+OHS: p < 0.001/p < 0.001. Mild vs. moderate OSAS: p = 0.971/p = 0.543. Mild OSAS vs. severe OAS: p = 0.110/p = 0.071. Mild OSAS vs. OSAS+OHS: p < 0.001/p = 0.001. Moderate OSAS vs. severe OSAS: p = 0.069/p = 0.358. Moderate OSAS vs. OSAS+OHS: p < 0.001/p = 0.013. Severe OSAS vs. OSAS+OHS: p = 0.010/p = 0.023. End-inspirium (right/left). Normal vs. mild OSAS: p = 0.549/p = 0.638. Normal vs. moderate OSAS: p = 0.388/p = 0.117. Normal vs. severe OSAS: p = 0.002/p = 0.005. Normal vs. OSAS+OHS: p < 0.001/p < 0.001. Mild OSAS vs. moderate OSAS: p = 0.771/p = 0.259. Mild OSAS vs. severe OAS: p = 0.003/p = 0.009. Mild OSAS vs. OSAS+OHS: p < 0.001/p < 0.001. Moderate OSAS vs. severe OSAS: p = 0.026/p = 0.278. Moderate OSAS vs. OSAS+OHS: p < 0.001/p = 0.004 Severe OSAS vs. OSAS+OHS: p = 0.063/p = 0.025
Ultrasonographic Measurement of the Diaphragm Thickness in Patients with Obstructive Sleep Apnea Syndrome

March 2020

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319 Reads

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9 Citations

Sleep and Breathing

Purpose The aim of this study was to evaluate the diaphragm thickness in patients with obstructive sleep apnea syndrome (OSAS). Methods This prospective study included patients who underwent polysomnography evaluation for the first time with a clinical suspicion of OSAS. All patients underwent polysomnographic evaluation with a 55-channel Alice 6 computerized system (Respironics; Philips, IL). Diaphragm thickness was measured as the distance between the peritoneum and the pleura using electronic calipers with a 7–12-MHz linear probe (PHILIPS EPIQ 5G). Results A total of 108 patients (67 males, 41 females) were enrolled in the current study. The mean age of the patients was 48.92 ± 11.47 years. The diaphragm thicknesses were significantly higher in OSAS patients both at end-inspirium and end-expirium compared with the normal group (p < 0.05). No significant difference was observed regarding the change level and thickening ratio (%) (p > 0.05). When the patients were allocated into OSAS subtypes; diaphragm thicknesses at the end of inspirium and expirium on both sides were significantly higher in the severe OSAS group and OSAS+OHS group compared with the other groups of normal, mild OSAS, and moderate OSAS subgroups (p < 0.05 for all). There was no significant difference between the groups regarding the thickening ratio (p > 0.05 for all). There was a positive correlation between the severity of OSAS and diaphragm thickness. Conclusion Diaphragm thickness seems to be increased in OSAS patients and the thickness correlates with the severity of OSAS. However, the thickness ratio of OSAS patients does not differ from that of normal subjects.


Ultrasound measurement of liver longitudinal length in a North Anatolian population: A community-based study

May 2018

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134 Reads

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21 Citations

Nigerian Journal of Clinical Practice

Zafer Özmen

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Fatma Aktaş

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ZelihaCansel Özmen

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[...]

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Osman Demir

Background: Liver size can be influenced by various factors, including malignant diseases, infective processes, and anthropometric variations among individuals from different geographical locations and races. Therefore, the exact definition of hepatomegaly in the ultrasonographic measurement of liver size is controversial. Moreover, the majority of studies regarding the study of liver size are not community-based. Aims: The aim of this study is to establish a range of normal liver sizes by ultrasonography with respect to age and sex in healthy individuals and to identify factors affecting liver size. Study design: This was a prospective, community-based study. Methods: Liver size was measured ultrasonographically from the midclavicular line in 822 individuals, of which 49.3% (n = 405) were male and 51.7% (n = 417) were female. Following physical examination, all participants provided blood samples. Height, weight, and waist circumference were recorded. The mean liver length was calculated for males, females, and for the whole study group. It was also determined whether there was an association between liver size and age, weight, height, body mass index (BMI), body surface area, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) enzyme levels. Results: The mean liver length was significantly different between males (150.04 ± 14.84) and females (147.57 ± 18.32, P = 0.034). Weight and BMI were the most strongly associated with liver size. There was a significant difference between liver size in individuals with normal and elevated levels of AST and ALT enzymes (P < 0.01). Conclusion: In a northern Anatolian Turkish population, liver size was greater among males than females. In light of these data, we believe our study may serve as a reference source for the evaluation of liver size.


ÇOCUKLUK DÖNEMİ OBSTRÜKTİF BÖBREK HASTALIKLARINDA DİNAMİK MANYETİK REZONANS ÜROGRAFİNİN TANI DEĞERİ

December 2017

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123 Reads

Journal of Contemporary Medicine



Is hemorrhage the reason in crimean-congo hemorrhagic fever patients with neurological signs and symptomsa

October 2017

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16 Reads

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2 Citations

Nigerian Journal of Clinical Practice

Purpose: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease can result in mortality varying from 3.0% to 50.0%. In this study, we wished to discuss computed tomography (CT) findings together with clinical and laboratory findings in patients who had disease-related neurological signs. Materials and methods: The study included patients who were diagnosed with CCHF. Seventeen patients that had neurological signs were enrolled as the patient group. As a control group, 40 patients diagnosed with CCHF and did not have neurological signs were enrolled. Patients who had neurological signs were examined with brain CT. Radiological and clinical findings of both groups were compared. Results: There were pathological findings in three patients while brain CT's of 14 patients were evaluated as normal. Blood urea nitrogen, lactate dehydrogenase, creatine kinase, total bilirubin, neutrophil, activated partial thromboplastin time, and C-reactive protein levels were significantly higher in the group with neurological signs whereas platelet count and calcium levels were significantly lower in this group. Six of 57 patients died during the follow-up period. Six patients who died were in the group, in which central nervous system (CNS) imaging study was performed. Conclusion: As the presence of CNS signs is a bad prognostic indicator in CCHF, they should be investigated carefully.


Citations (11)


... In particular, endothelial cells are severely affected by the disease (8). Although the destruction of the vascular endothelium by the virus is known, there are insufficient studies in the literature on changes in abdominal vascular structures that may develop due to the disease (9)(10)(11). Therefore, our study aims to assess whether any diameter changes are detected on abdominal multidetector computed tomography (MDCT) in CCHF in the portal vein (PV), hepatic artery (HA), splenic vein (SV), splenic artery (SA), superior mesenteric vein (SMV), and superior mesenteric artery (SMA). ...

Reference:

Evaluation of abdominal vascular structures by multidetector computed tomography in Crimean–Congo hemorrhagic fever patientsKırım Kongo kanamalı ateşi hastalarında abdominal vasküler yapıların çokkesitli bilgisayarlı tomografi ile değerlendirilmesi
Abdominal US Findings of Crimean-Congo Hemorrhagic Fever
  • Citing Article
  • June 2020

Journal of Contemporary Medicine

... It is a non-invasive, cost-effective, and easily operable alternative that provides dynamic imaging [13]. We found that T FRC and T TLC in the OSAHS group especially severe OSAHS group were significantly higher than those in the control group, which is consistent with other studies [22]. Previous studies have reported that obesity is a risk factor of diaphragmatic hypertrophy [4,23]. ...

Ultrasonographic Measurement of the Diaphragm Thickness in Patients with Obstructive Sleep Apnea Syndrome

Sleep and Breathing

... Similarly, Tarawneh et al. [27] showed that mean liver length was reported to be 12.3 cm. A recent study from Turkey by Özmen et al. [1] reported the mean liver length as 14.9 ± 1.6 cm in the study population. The present study revealed that mean liver length was 11.98 ± 1.54 cm in normals. ...

Ultrasound measurement of liver longitudinal length in a North Anatolian population: A community-based study
  • Citing Article
  • May 2018

Nigerian Journal of Clinical Practice

... However, ecchymosis, petechia, vaginal bleeding, and epistaxis can also be observed. In addition, intracranial bleeding, gastrointestinal bleeding, and alveolar hemorrhage that are life-threatening and often responsible for mortality can be observed as well [1][2][3][4]. The geographical location, exposure to animals with ticks, and contact with suspicious infected blood and blood products in the patients' history are helpful in diagnosis. ...

Is hemorrhage the reason in crimean-congo hemorrhagic fever patients with neurological signs and symptomsa
  • Citing Article
  • October 2017

Nigerian Journal of Clinical Practice

... where X and Y represent the substrate of the reaction, M and N represent the product of the reaction, and then K 1 and 2 represent the kinetic parameters of the reaction and the kinetic parameters of the reverse reaction, respectively [10]. ...

Evaluation of morphological changes in pharynx with dynamic CT and MRI in snoring patients

Revista médica de Chile

... Further confirmation can be sought through serological profiling via ELISA methodology targeting specific IgM and IgG antibodies against viral antigens [17] . Radiological investigations, particularly thoracic CT scans, have elucidated notable pulmonary manifestations, including parenchymal infiltrates and pleural effusions in CCHF patients [18] . ...

Thorax CT findings in patients with Crimean-Congo hemorrhagic fever (CCHF)

SpringerPlus

... Further research is needed to investigate the reasons for this sex disparity and to develop targeted prevention and control strategies for CCHF in the country. These findings are consistent with other CCHF studies conducted in Turkey (26) and Iran (27). Some studies have concluded that the higher occurrence of CCHF in males is due to the more frequent exposure of men to CCHF risk factors, such as farming and animal handling (13,14). ...

Does Crimean-Congo Hemorrhagic Fever Cause a Vasculitic Reaction with Pulmonary Artery Enlargement and Acute Pulmonary Hypertension?

Lung

... Изследван е рискът от ПР дали може да бъде измерван като се използва стойността на съотношението на плацентарното преразтягане (SR), измерена през втория триместър, използвайки соноеластография в реално време [44]. При 70 бременни жени във втория триместър са използвани две различни тъкани като референти. ...

Is evaluation of placenta with real time sonoelastography during the second trimester of pregnancy an effective method for the assessment of spontaneous preterm birth risk?
  • Citing Article
  • April 2016

Clinical Imaging

... In particular, endothelial cells are severely affected by the disease (8). Although the destruction of the vascular endothelium by the virus is known, there are insufficient studies in the literature on changes in abdominal vascular structures that may develop due to the disease (9)(10)(11). Therefore, our study aims to assess whether any diameter changes are detected on abdominal multidetector computed tomography (MDCT) in CCHF in the portal vein (PV), hepatic artery (HA), splenic vein (SV), splenic artery (SA), superior mesenteric vein (SMV), and superior mesenteric artery (SMA). ...

The evaluation of abdominal findings in Crimean-Congo hemorrhagic fever

Abdominal Radiology

... In case 4, there is a concurrence of thoracic and sacral dysgeneses, which has been rarely reported by previous authors. [21] LMMC is an uncommon type of SB involving herniation of a lipoma from the spinal canal through a defect in the bony spine and meninges into the subcutaneous tissue, where it presents as a lump. [22] The fat tissue encroaches onto the dorsal aspect of the spinal cord and accompanying nerve roots and may cause varying degrees of neurological dysfunction and tethered cord syndrome if left untreated. ...

Multiple spinal anomalies concurrent with sacral agenesis
  • Citing Article
  • December 2015

The Spine Journal