Yufen Zhao’s research while affiliated with Ningbo University and other places

... Therefore, systems based on the analyte-driven aggregation of AuNPs have been utilized for the colorimetric sensing of specific analytes through detection reporters on the AuNPs [32][33][34][35][36][37][38][39]. Notably, the ability of a single sensor to simultaneously detect multiple analytes has recently gained significant attention, owing to advantages including cost reduction and improved analytical efficiency [40][41][42][43][44]. Consequently, the design and synthesis of colorimetric sensors exhibiting high selectivity and sensitivity toward MOX, CIP, and Cr(III) have attracted increasing attention [45][46][47]. ...

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An Ultra-Sensitive Colorimetric Sensing Platform for Simultaneous Detection of Moxifloxacin/Ciprofloxacin and Cr(III) Ions Based on Ammonium Thioglycolate Functionalized Gold Nanoparticles

... Some gram-negative bacteria, specifically those from the phylum Proteobacteria in which E. coli is classed, possess homologues of McsA and McsB [42]. Moreover, McsB was recently reported to bind in transient to the CtsR-DNA complex [43]. Therefore, if the role of McsB in E. coli and S. aureus are similar, it may be plausible that the entire McsB-CtsR (or equivalent E. coli repressor)-DNA-MMV1634391 complex was stabilised in the endogenous environment. ...

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Screening the Pandemic Response Box identifies novel ligands of the Staphylococcus aureus protein arginine kinase, McsB

... These compounds have gained significant attention in the field of medicinal chemistry, where they exhibit activities such as antimicrobial, antiviral, antidiabetic, antioxidants and anticancer activity [1,2]. The structural framework of benzimidazole provides a versatile scaffold for the synthesis of novel compounds, which are capable of interacting with various biological targets due to their heteroatom-rich nature and ability to participate in hydrogen bonding and π-π stacking interactions [3,4]. ...

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Synthesis and Antioxidant Potential of Novel Benzimidazole Derivatives: A Comparative Study of Experimental and DFT Insights

... Infrared spectroscopy of inner and outer layers of the travertine sample reveals three principal absorption features for calcite between 400 and 4000 cm −1 (Figure 4a). The antisymmetric stretching mode (ν 3 ) of the carbonate ion (CO 3 2− ) produces a prominent band at 1420 cm −1 , while outof-plane bending (ν 2 ) and in-plane bending (ν 4 ) appear at 872 and 709 cm −1 , respectively. These bands' shift is influenced depending on how each carbonate C−O bond interacts with infrared radiation. ...

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Calcium Carbonate as a Potential Template for the Origin of Life: Coupled Inorganic–Organic Geochemistry of Travertine Deposit from Puga Hot Spring

... In 2024, Wang et al. [62] reported an electrochemical method for the synthesis of phosphorylated indoles in the presence of Cp 2 Fe as the mediator under mild reaction conditions without the need for external oxidants. This method improves the scalability of the resulting products, which also exhibit enhanced anticancer activity. ...

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Recent advances in the electrochemical synthesis of organophosphorus compounds

... Detailed descriptions of deep learning models for other PTM types are provided in supplementary materials (Section 1) due to space limitations [10]. ...

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UniPTMs: The First Unified Multi-type PTM Site Prediction Model via Master-Slave Architecture-Based Multi-Stage Fusion Strategy and Hierarchical Contrastive Loss

... Necroptosis is classified as a kind of programmed necrosis, which is manifested as resultant cell leakage following cell swelling and subsequent plasma membrane disruption, thereby provoking the immune system and strongly incurring proinflammatory effects (Shi et al. 2024). Necroptosis is involved in secondary brain injury subsequent to traumatic brain injury, ischemic stroke, ICH, and subarachnoid hemorrhage (L. ...

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Evaluation of Prognostic Implication of Serum Mixed Lineage Kinase Domain‐Like Protein in Acute Primary Supratentorial Intracerebral Hemorrhage: A Multicenter Prospective Cohort Study

... Organophosphorus compounds are vital in various applications spanning organic synthesis, agrochemicals, pharmaceuticals, and innovative materials. [1][2][3][4][5][6][7][8] Among them, vinylated phosphorus compounds are of significant relevance in the pharmaceutical industry due to their potential to synthesize pharmacologically important and biologically active molecules, such as antibiotics and enzyme inhibitors. Furthermore, alkenyl phosphine oxides are recognized for their utility as monomers in polymer and materials science, emphasizing the extensive and critical role of phosphorus in advancing diverse scientific fields. ...

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Synthesis of Terminal Vinyl Phosphine Oxides via Desulfonative C—P Formation from Alkenyl Sulfonium Salts

... SCHEME 9 | N-to C-solution-phase synthesis using ynamide activation. prepared under so claimed "prebiotic conditions" in which Nacetamido amides were heated with amino amides in 0.5 M NaOH at 80 °C [58]. Moreover, peptides have been synthesized by ring-opening of N-alkyl N-Boc-diketopiperazines without epimerization on heating with amino esters in the neat and with peptide esters in toluene with a benzoic acid catalyst [59]. ...

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N ‐ to C ‐Peptide Synthesis, Arguably the Future for Sustainable Production

... The cyclization occurred between 2-pyridinemethylamine and various aromatic aldehydes. This was a straightforward approach in which I 2 /H 2 O 2 worked as medium and afforded excellent yields in the range of 65%-98% (Scheme 32)[37].The proposed mechanism started with the reaction of H 2 O 2 and I 2 , also H 2 O 2 oxidized benzaldehyde to benzoic acid. Again, in the presence of I 2 , pyridine methylamine attacked benzaldehyde and formed an intermediate iminium ion 91, which changes to intermediate 92 with intramolecular attack of N-atom of pyridine. ...

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Synthetic Approaches Toward Imidazo‐Fused Heterocycles: A Comprehensive Review