Yu-ting Lu’s research while affiliated with China Pharmaceutical University and other places

... ASGM attracts rural populations through the incomes it provides [14] [15]. Unfortunately, all over the world, the miner considered exposure to MeHg pollution as minimal to absent [16] [17]. Journal of Water Resource and Protection ...

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Mercury Levels Assessment in the Population of Aby and Frambo Villages in the Vinicity of Aby Lagoon in Côte d'Ivoire (West Africa)

... Spring viremia carp virus is one of the important viral pathogens in warm water species. This virus was shown to induce ER stress (elevated GRP78, BECLIN1, and LC3II/LC3I protein expression), autophagy, apoptosis (flow cytometry), and also protein processing pathways in the ER [162]. Autophagy, endocytosis, phagosome, and protein processing in ER were also enriched in coelomocytes of sea urchins challenged with Vibrio anguillarum baths [163]. ...

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Endoplasmic Reticulum Stress in Aquaculture Species

... The new morphological findings of Protorosaurus speneri were integrated into a character-taxon matrix for phylogenetic analysis that focuses on the interrelationships of non-archosauriform archosauromorphs. This matrix was first introduced in Spiekman, Fraser, et al. (2021) and has subsequently been updated in Lu and Liu (2023), Spiekman, Ezcurra et al. (2024), and Wang et al. (2023Wang et al. ( , 2024. For this contribution, 28 character scorings were modified for Protorosaurus speneri (see Dryad at https://doi.org/ ...

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New data on the skull of Protorosaurus speneri (Reptilia: Archosauromorpha) and their phylogenetic significance

... For example, autophagy and antigen processing may be involved in minimizing the number of infectious particles in the cell (6)(7)(8)(9). On the other hand, other fish rhabdoviruses may manipulate autophagy to evade immunity, promote replication and facilitate their release from infected cells (10)(11)(12). Transmission electron microscopy (TEM) has allowed visualization of defense mechanisms in VHSV-exposed RBCs related to the elimination of viral proteins and antigen presentation, which is the formation of vesicles similar to autophagosomes (7). The adaptive immune response of fish RBCs involves the expression of major histocompatibility complex (MHC) class I and II molecules (7,13). ...

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Endoplasmic reticulum stress triggers unfolded protein response as an antiviral strategy of teleost erythrocytes

... Comparing differences in exposure patterns derived from wastewater treatment plants (WWTPs) influents is a common feature of WBE studies. Examples can be found between (Estévez-Danta et al., 2022;Baz-Lomba et al., 2016) and within countries (Gao et al., 2020;Gracia-Lor et al., 2020), within a regional area of a country (Xu et al., 2023;Zheng et al., 2017) or at the city level (Centazzo et al., 2019;Asicioglu et al., 2021). Differences in potentially influencing environmental conditions, e.g. ...

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Impact of physicochemical parameters on nicotine metabolites and Bisphenol A in municipal wastewater: A pilot study in a German metropolitan area

... Tumor volumes typically reached around 100 mm^3^ within three weeks, at which point the mice were randomly assigned to two groups. The treatment group received daily intragastric doses of Triptonide (10 mg/kg), based on prior studies and preliminary experiments [9,23], while the control group was given an equivalent volume of saline over 21 consecutive days. Tumor dimensions were measured using calipers, and tumor volume was calculated using the formula: (length × width^2^)/2. ...

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Triptolide induces immunogenic cell death in cervical cancer cells via ER stress and redox modulation

... Meanwhile, the tertiary ring nitrogen itself was prone to be oxidized, forming N-oxide derivatives. 33 Furthermore, DP 9, which served as a synthetic intermediate, exhibited a similar susceptibility to oxidation. ...

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Identification of degradation products of brivaracetam using liquid chromatography quadrupole time‐of‐flight tandem mass spectrometry: Degradation pathway elucidation

... By analyzing the biomarkers of drug residues in domestic sewage, the daily mass loads of illicit drugs entering a wastewater treatment plant (WWTP) could be calculated, which can offer valuable insights into temporal trends of drug consumption, free from any self-report bias [7][8][9] or ethical concerns [10,11]. Since the application of WBE in illicit drugs analysis was first introduced in 2001 [12] and applied in 2005 [13], using WBE to monitor the use of drugs has been practiced in multiple countries and regions [14][15][16][17][18][19][20]. In addition to the documented quantitative analysis of targeted illegal drugs in sewage utilizing triple quadrupole mass spectrometry, a suspect screening strategy for illicit drug investigation using WBE and high-resolution mass spectrometry (HRMS) has been suggested [21][22][23][24]. ...

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Investigation of New Psychoactive Substances (NPS), Other Illicit Drugs, and Drug-Related Compounds in a Taiwanese Wastewater Sample Using High-Resolution Mass-Spectrometry-Based Targeted and Suspect Screening

... Among all techniques, mass spectrometry is a powerful technique for the analysis of peptide and protein therapeutics. Hyphenated LC-MS can characterise peptides and associated impurities since it has an excellent combination of robustness, high-resolution power, and speed of analysis (Pan et al. 2011;Han et al. 2021;Molineau et al. 2022). Application of soft ionization techniques such as electrospray ionization (ESI) and matrixassisted laser desorption ionization (MALDI) can identify intact molecular mass of peptides or peptide-mass fingerprinting generated upon enzymatic digestion while tandem mass spectrometry (MS/MS) can provide information even in amino acid sequence (Thiede et al. 2005;Duncan and Gibson 2012). ...

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Forced Degradation Products of Liraglutide: A Comparative Study of Similarity Between Originator and Analogue Version by Liquid Chromatography–Mass Spectrometry

... The lipophilic moieties of tazarotene, such as its thiochroman ring, confer low solubility in aqueous solvents [13,14], posing challenges for some quantification methods [15]. Several liquid chromatography methods for the quantification of tazarotene and tazarotenic acid have been described [16][17][18][19][20]. While the majority focus on analyzing the analytes in plasma samples or topical formulations [16,17,19,20], one notable study investigated mini-pig skin [18]. ...

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Optimization and Validation of an Ultra-Performance Liquid Chromatography with Quadrupole Detector Mass Spectrometry Quantification Method for the Simultaneous Detection of Tazarotene and Tazarotenic Acid in Porcine Skin: An In Vitro Study