Yolanda Soracipa's research while affiliated with Nueva Granada Military University and other places

Publications (44)

Article
Background: from probability theory and probabilistic random walk, predictions about the quantity of cases of a given phenomenon for certain year, such as epidemics of dengue, have been previously obtained with results close to 100% in precision. Objective: To confirm the applicability of a methodology based on probability and probabilistic random...
Article
Full-text available
La correcta interpretación del trazado del monitoreo fetal electrónico es un desafío para la clínica actual. Recientemente se desarrolló una metodología diagnóstica fundamentada en las teorías de probabilidad y la entropía, que logró evaluar de manera objetiva y reproducible el trazado de la monitoría fetal diferenciando normalidad de enfermedad y...
Article
Full-text available
p> Resumen Antecedentes: Con base en la teoría de la probabilidad y las proporciones de la entropía no equiprobable en el contexto de la teoría de los sistemas dinámicos se desarrolló una metodología de evaluación de la dinámica cardiaca. Objetivo: Confirmar la aplicabilidad clínica de la metodología diagnóstica basada en la probabilidad y la en...
Article
Full-text available
p> Resumen Antecedentes: Con base en la teoría de la probabilidad y las proporciones de la entropía no equiprobable en el contexto de la teoría de los sistemas dinámicos se desarrolló una metodología de evaluación de la dinámica cardiaca. Objetivo: Confirmar la aplicabilidad clínica de la metodología diagnóstica basada en la probabilidad y la en...
Article
Full-text available
Introduction: Cardiac irregularity is adequately described by means of fractal geometry, which was the basis for the development of a diagnosis of the left ventriculogram. Methods: All possible permutations of similarity degrees from fractal dimensions were simulated for the ventricle in systole, diastole and the totality. Permutations were defined...
Article
Full-text available
Introducción: A partir de la teoría de los sistemas dinámicos y de la teoría de la probabilidad se han desarrollado metodologías altamente sensibles de aplicación clínica que permiten diferenciar normalidad, enfermedad y evolución hacia la enfermedad cardiaca. Métodos: Se seleccionaron los registros Holter de siete casos normales y 73 con diagnóst...
Article
Fractal geometry has proven to be adequate for mathematical description of irregular objects such as the human body. Based on this geometry, an objective and reproducible representation of a left ventricle was previously developed. The aim of this research was to develop a simulation based on this methodology that allows establishing all possible l...
Article
Full-text available
Previamente, se desarrolló una metodología diagnóstica para lesiones preneoplásicas y neoplásicas de células de cuello uterino, a partir de medidas euclidianas y fractales simultá- neas. En este trabajo, el objetivo era confirmar la concordancia diagnóstica de la metodología en células normales y en diferentes estadios de lesión celular. Se tomaron...
Article
Full-text available
A diagnostic methodology for preneoplastic and neoplastic lesions of cervical cells from simultaneous fractals and euclidean measures was developed. In this work the objective was to confirm the diagnostic concordance of the methodology in normal cells and in different stages of progression to disease. For this, 60 photographs of cervical squamous...
Article
Introducción: La dinámica cardíaca ha sido caracterizada a partir de la teoría de los sistemas dinámicos y la geometría fractal, permitiendo generar metodologías de aplicación clínica. Objetivo: desde los sistemas dinámicos, se desarrollará una metodología de evaluación de los pH y presiones de dióxido de carbono arteriales y venosos para paciente...
Article
Full-text available
Introducción. Fenómenos como la monitoria fetal y el repertorio T específico contra el alérgeno Poa p9 han sido evaluados con la ley de Zipf/Mandelbrot. Objetivo. Establecer una metodología de caracterización de la dinámica del dengue en Palmira, Valle del Cauca, Colombia, fundamentada en la ley de Zipf/Mandelbrot y aplicada al periodo 2001-2004....
Article
Full-text available
Background: the theory of dynamic systems and fractal geometry has been useful to evaluate the cardiac dynamics in adults and neonates. From this perspective, there has been recently developed a new diagnostic method of the chaotic cardiac dynamics in neonates. Objective: to confirm through a blind study the diagnostic capacity of this methodology...
Article
Full-text available
Antecedentes: Se desarrolló un método diagnóstico fractal para evaluar células del cuello uterino utilizando el concepto de Armonía Matemática Intrínseca (AMI) y variabilidad celular, el cual diferencia matemáticamente células normales de células L-SIL y H-SIL, haciendo innecesario el diagnóstico de células ASCUS.Objetivo: confirmar la capacidad di...
Article
La aplicación de la geometría fractal y la teoría de los sistemas dinámicos han logrado caracterizar de manera objetiva y reproducible la dinámica cardiaca a partir de la construcción de atractores caóticos.
Article
Full-text available
Resumen Objetivo Desarrollar una metodología diagnóstica físico-matemática que diferencie normalidad de enfermedad aguda, en registros electrocardiográficos continuos y Holter, disminuyendo el tiempo de evaluación de 21 a 16 h, mediante los espacios de ocupación de atractores dinámicos. Métodos Estudio de corte trasversal en pacientes ingresados...
Article
Full-text available
Background: the theory of dynamic systems and fractal geometry has been useful to evaluate the cardiac dynamics in adults and neonates. From this perspective, there has been recently developed a new diagnostic method of the chaotic cardiac dynamics in neonates. Objective: to confirm through a blind study the diagnostic capacity of this methodology...
Article
Full-text available
The prevalence of overweight in children worldwide is rising in developing countries. Diseases associated with childhood overweight as asthma, sleep apnea and diabetes mellitus, the latter being the most common among children and adolescents, imply another problem: the high cost to health, which has been analyzed by the National Center for Health S...
Article
Full-text available
p class="Cuerpodeltexto50">Antecedentes: A partir de la teoría de sistemas dinámicos se desarrolló una metodología que permite diferenciar dinámicas cardíacas normales, en distintos niveles de enfermedad y en evolución entre estos estados. Esto se hizo cuantificando en el espacio de fases, mediante la entropía y sus proporciones, la probabilidad de...
Article
Based on dynamic systems theory, a methodology that allows to differentiate normal cardiac dynamics, different levels of abnormality and evolution between these states, was developed. This was done by quantifying the probability of ordered pairs of heart rates in the phase space, through entropy and its proportions. To apply in a clinical setting t...
Article
The development of a mathematical law for chaotic dynamical systems has allowed to develop a methodology for the mathematical evaluation of cardiac dynamics which quantifies the differences between normality and disease, as well as their evolution. Material and methods: 70 Holter records, 60 with cardiac arrhythmias and 10 normal were taken. From t...
Article
Full-text available
Previously a refinement of a methodology was developed based on set theory and probability, with the aim of improving the predictive ability of CD4 T cells (LT-CD4) for HIV/AIDS from the total number of leukocytes and lymphocytes. In this work the clinical applicability of the method was shown by refining prediction in 150 samples. Taking data of l...
Article
Full-text available
Introducción: la estructura cardiaca es por naturaleza, irregular, su adecuada caracterización se hace mediante la aplicación de la geometría fractal. Desde esta geometría se desarrolló un diagnóstico objetivo del ventriculograma izquierdo. Objetivo: desarrollar una generalización teórica de la dinámica ventricular izquierda en los estados de norma...
Article
Introduction: Cardiac structure is irregular by nature; its proper characterization is done by application of fractal geometry. From this geometry an objective diagnosis of left ventriculogram was developed. Objective: to develop a theoretical generalization of left ventricular dynamics in states of normality and mild disease, from the objective an...
Article
Basados en geometría fractal se hizo un diagnóstico objetivo y reproducible de células de cuello uterino, que diferencia las normales de aquellas con lesión de bajo grado (LEIBG) o cancerígenas, identificando en forma cuantitativa las células ASCUS. Objetivo: establecer una metodología diagnóstica de las células cervicales normales y preneoplásicas...
Article
Obesity and overweight are public health problems both globally and in Latin America. The theory of probability and probabilistic random walk have been the basis for developing predictions of the dynamics of different epidemics. In this work, the growth of obesity in four countries is studied based on the random walk, to confirm the ability of the...
Article
Full-text available
La obesidad y el sobrepeso constituyen problemas de salud pública tanto a nivel mundial como en América Latina. La teoría de la probabilidad y la caminata al azar probabilista han sido base para el desarrollo de predicciones de la dinámica de diferentes epidemias. En este trabajo se estudió el crecimiento de la obesidad en cuatro países con base en...
Article
Full-text available
HIV diagnosis, prognostic and treatment requires T CD4 lymphocytes' number from flow cytometry, an expensive technique often not available to people in developing countries. The aim of this work is to apply a previous developed methodology that predicts T CD4 lymphocytes' value based on total white blood cell (WBC) count and lymphocytes count apply...
Article
Full-text available
From dynamical systems theory and a mathematical deduction of Box-Counting equation, a chaotic exponential law that objectively differentiates normal cardiac dynamics from pathological ones, and the evolution between these states was inferred. 25 Holters were taken from a database: 16 with arrhythmias and 9 clinically diagnosed as normal but with v...
Article
Full-text available
Las ecuaciones diferenciales se clasifican de acuerdo con el tipo, el orden y si son o no lineales; pueden expresar leyes de los fenómenos naturales como las leyes del movimiento de Newton, enunciadas en el contexto de la cinemática para el sistema dinámico planetario. La teoría de los sistemas dinámicos ha sido base, junto con otras teorías física...
Article
Differential equations are classified according to type, order and whether they are linear or not; they can express natural phenomena laws such as Newton's movement laws, set in the context of kinematics for the planetary dynamic system. Dynamical systems theory has been a foundation along with other physical and mathematical theories, for the deve...
Article
Full-text available
Basados en la teoría de conjuntos se desarrolló una metodología de predicción del recuento de linfocitos T CD4 (LT-CD4) a partir del número de leucocitos y linfocitos totales. Se aplicó esta metodología a 500 muestras provenientes de pacientes con VIH con el fin de confirmar la capacidad predictiva de la metodología. Las triplas de datos de leucoci...
Article
Full-text available
h4>RESUMEN La teoría de sistemas dinámicos cuantifica los estados y la evolución de los sistemas. Con base en esta teoría se creó una nueva metodología que cuantifica parejas ordenadas de frecuencias cardiacas en el espacio de fases de mediante la probabilidad y proporciones de la entropía, diferenciando clínicamente normalidad, enfermedad crónica...
Article
Full-text available
Cardiac chaotic dynamics have been evaluated from dynamic system theory, fractal geometry, and a power law that deduces all possible discrete chaotic attractors allowing the development of a diagnostic method with clinical application. To confirm the clinical applicability of the diagnostic method based on the exponential law in normal and with dif...
Article
Full-text available
Heart dynamic characterized within the context of dynamical systems theory allows differentiating and predicting normal cardiac states, different levels of disease, as well as evolution towards disease. The purpose of this study is to apply a previously developed methodology to 450 electrocardiographic registers to establish its effectiveness and c...
Article
Recibido agosto 5 de 2011; aceptado septiembre 6 de 2011. Resumen El proceso teórico que siguió Kepler para determinar lá orbita de Marte y , posteriormente, enunciar las leyes del movimiento planetario, requirió de la convergencia de múltiples elementos, como la concepción cosmológica que asume y su formación matemática y astronómica. El propósito...
Article
Full-text available
The dynamical systems theory allows quantification of the state and evolution of dynamical systems. Summing fractal geometry, these theories have been useful to assess cardiac chaotic dynamic; developing clinical researches with acute myocardial infarction and, on the other side, finding through entropy law a diagnostic aid for clinical application...
Article
Full-text available
Fractal geometry is employ to characterize the irregular objects and had been used in experimental and clinic applications. Starting from a previous work, here we made a theoretical research based on a geometric generalization of the experimental results, to develop a theoretical generalization of the stenotic and restenotic process, based on fract...
Article
The aim of this research is apply the predictive nonameric binding methodology to HLA class II central region, to nonameric peptides of MSA-2 and AMA-1 proteins from Plasmodium falciparum, and to 492 nonameric overlapped peptides for three theoretical proteins with size of 500 residues.A predictive binding theory to HLA class II based on S/k propor...
Article
Full-text available
One of the Plasmodium falciparum merozoite proteins, EBA-140, also known as BAEBL or PfEBP-2, shares structural features and homology with EBA-175 and EBA-181. Studies on the sub-cellular localization suggest a micronem localization. A probability space was built where the possibility of appearance by position for each of the 20 amino acids in EBA-...
Article
Full-text available
One of the Plasmodium falciparum merozoite proteins, EBA-140, also known as BAEBL or PfEBP-2, shares structural features and homology with EBA-175 and EBA-181. Studies on the sub-cellular localization suggest a micronem localization.A probability space was built where the possibility of appearance by position for each of the 20 amino acids in EBA-1...
Article
Full-text available
p> Resumen La probabilidad y la entropía han sido empleadas para caracterizar física y matemáticamente péptidos de alta unión de proteínas de malaria al eritrocito. Estudios sugieren que la proteína AMA- 1 del Plasmodium Falciparum se une al eritrocito posiblemente jugando un papel en la infección. Se efectuó una cuantificación de la frecuencia...
Article
Full-text available
Nueva metodología de ayuda diagnóstica de la dinámica geométrica cardiaca. Dinámica cardiaca caótica del Holter. Rev. Acad. Colomb. Cienc. 35 (134): 5-12. 2011. ISSN 0370-3908. Por medio de la teoría de los sistemas dinámicos es posible cuantificar el estado y la evolución de sistemas dinámicos; la dinámica caótica cardiaca ha sido evaluada desde l...

Citations

... Other areas of medicine in which it is possible to observe the potential of studies supported by physical and mathematical theories, such as the one applied in this study, include studies on arterial and cell structures [40,42]. Moreover, methods contributing to immunology [43], epidemic prediction [44], and CD4+ have been developed based on the leukocyte count of patients with HIV/AIDS [45]. These results show that this type of research can bring solutions in all fields of medicine and that this discipline can have the same predictive level as physics. ...
... Este trabajo evidencia el carácter general de la ley, al ser aplicable en rangos de tiempo menores a los estudiados en la metodología inicial, desarrollada en 21 horas, evidenciando que es posible establecer afirmaciones objetivas y reproducibles en medicina a través de un pensamiento físicomatemático estricto, al margen de otras consideraciones. Siguiendo esta forma de pensamiento se han encontrado diagnósticos y predicciones en fenómenos médicos como la hematología 26 , el proceso de reestenosis arterial 27 , la dinámica cardiaca del adulto 28 y fetal 29 , las alteraciones celulares en el desarrollo de cáncer de cuello uterino 30 , la predicción de linfocitos T CD4 en pacientes infectados por el virus del VIH 31 , la predicciones de unión peptídica al HLA clase II 32 o la predicción de brotes de malaria en 820 municipios de Colombia 33 e incluso predicciones de mortalidad 34 . ...
... In one of these studies, left ventriculograms were analyzed under fractal geometry to establish groups of different severity according to the values of fractal dimension. 27 Following this same line of research but applied to analyzing functional complex patterns, it is important to mention that cardiac dynamics have been diagnosed with the dynamic systems theory, 28 and entropy, 29 and even predictions of mortality in the intensive care unit have been achieved. 30 Similarly, predictions of epidemics have also been made, 31 and phenomena such as the binding of peptides to HLA class II have been characterized and predicted. ...
... Innovaciones desde los sistemas dinámicos han sido implementadas por Goldberger et al. 16,17 , quienes evidenciaron que la concepción homeostática tradicional no representaba de manera fidedigna el comportamiento real de la dinámica cardiaca, la cual se caracteriza por patrones altamente regulares o excesivamente irregulares en condiciones patológicas, mientras que la normalidad se establece como un estado intermedio entre estos extremos Rodríguez et al. 18 , han desarrollado nuevas metodologías desde teorías como la probabilidad o los sistemas dinámicos, logrando métodos diagnósticos de aplicabilidad clínica. ...
... Later it was applied to ICU, reducing the evaluation time of cardiac dynamics from 24 to 16 hours, achieving to establish objective and reproducible mathematical measurements that distinguish normal dynamics from those with acute illness, allowing evaluate the evolution between these states in less time (Rodríguez et al., 2015d). Also a cardiac chaotic law (Rodríguez 2011) was developed, which was applied to 115 patients (Rodríguez et al., 2013a), and finally with the probability theory and the principle of entropy was possible to differentiate normality from the chronic and acute disease, and states between them (Rodríguez, 2010b;Rodriguez, 2012a;Rodríguez et al., 2013e;Rodríguez, 2014b;Rodríguez, 2015). In the same way, the complexity degree of the normal and acute cardiac dynamics from Zipf-Mandelbrot law was found (Rodríguez et al., 2015c). ...
... Se han propuesto diferentes modelos matemáticos epidemiológicos para el análisis de diversas enfermedades, entre ellas, la infección por el virus sincitial respiratorio (4)(5)(6)(7)(8). También, se han utilizado modelos basados en ecuaciones diferenciales para explicar la dinámica del RSV en la población (4,5,7). ...
... In one of these studies, left ventriculograms were analyzed under fractal geometry to establish groups of different severity according to the values of fractal dimension. 27 Following this same line of research but applied to analyzing functional complex patterns, it is important to mention that cardiac dynamics have been diagnosed with the dynamic systems theory, 28 and entropy, 29 and even predictions of mortality in the intensive care unit have been achieved. 30 Similarly, predictions of epidemics have also been made, 31 and phenomena such as the binding of peptides to HLA class II have been characterized and predicted. ...
... In the framework of theoretical physics and contemporary mathematics such as statistical mechanics, chaos, dynamic systems and quantum mechanics, the design of predictive methodologies from an acausal perspective (24)(25)(26)(27)(28)(29)(30), simplify the problems found in the different scenarios of Medicine. Unlike all the risk factors and the qualitative factors linked to the study of epidemics that usually make it di cult to obtain predictions. ...
... There are other studies that use the fractal dimension for the analysis of radiological images and pathological histological samples, as an alternative diagnostic method to conventional methods. [11][12][13][14] The need for a new technology is permissible to satisfy diagnostic methods in an age full of scientific events. The use of fractal mathematics in response to this need in the field of medical sciences, overcoming the barriers of traditional tools, it is necessary, of course. ...
... Establish differences in four different behavioral states of the normal newborn (active awake, awake still, asleep in REM sleep and still asleep) [11] was possible through of a mathematical methodology. Also, empirical values of cardiac dynamics were taken at three moments before the sepsis episode to generate a neonatal chaotic attractor representative of each state, differentiating in a geometric manner the episodes prior to neonatal sepsis [12]. Subsequently, this type of measure was applied to the development of a diagnostic method of neonatal cardiac dynamics, finding that the space occupied by the attractor is smaller as it approaches the acute state revealing the clinical condition of the neonate [13][14]. ...