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April 2016
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36 Reads
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5 Citations
Chemistry of Natural Compounds
Two new chalcones, podocarchalcones A and B (1 and 2), together with five known chalcones (3–7), were isolated from the whole plants of Desmodium podocarpum. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. Compounds 1–7 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity, and they exhibited activity with inhibition rates in the range of 15.2–22.4%, respectively.
October 2015
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7 Reads
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4 Citations
Chemistry of Natural Compounds
Two new flavones, 6,4'-dimethoxy-8-formylflavone (1) and 6,7-dimethoxy-8-acetyl-4'-hydroxyflavone (2), together with five known flavones (3-7), were isolated from the leaves and stems of Hypericum chinense. The structure of 1-7 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1, 2, 6, and 7 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 shows high anti-TMV activity with an inhibition rate of 31.4%, which is close to that of the positive control.
October 2015
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39 Reads
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2 Citations
Asian Journal of Chemistry
A new isocoumarin, caudacoumarin D (1) was isolated from the bark of Lindera caudata. Its structure was elucidated by spectroscopic methods, including extensive 1D NMR and 2D NMR techniques. The antitobacco mosaic virus (anti-TMV) activity of 1 was evaluated. The results revealed that caudacoumarin D (1) showed anti-TMV activity with inhibition rate of 17.2 %.
October 2015
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64 Reads
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10 Citations
Asian Journal of Chemistry
A new butyrolactone, asperphenol C (1), was isolated from the fermentation products of an endophytic fungus Aspergillus versicolor. Its structure was elucidated by spectroscopic methods including extensive 1D-And 2D NMR techniques. Compound 1 was also tested for its antitobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 exhibited anti-TMV activity with inhibition rate of 22.1 %.
July 2015
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18 Reads
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4 Citations
Asian Journal of Chemistry
A new biphenyl i.e., 3-methoxy-5-methoxycarbonyl-4-hydroxy-biphenyl (1) was isolated from the stems of Garcinia oligantha. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR. This biphenyl was tested for its cytotoxicity against five human tumor cell lines (NB4, A549, SHSY5Y, PC3 and MCF7) and it showed modest cytotoxicity against SHSY5Y, A549 and MCF7 cell with IC50 values of 7.1, 6.2 and 4.8 μM, respectively.
February 2015
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25 Reads
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9 Citations
Chemistry of Natural Compounds
Two new phenolic compounds, 6-hydroxy-7-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one (1) and 7-hydroxy-6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one (2), together with six known phenols (3-8), were isolated from the stems of Cassia siamea. The structure of 1-8 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-8 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 have potential anti-TMV activity with inhibition rates of 28.2 and 23.5%, respectively. Compounds 3-8 also showed anti-TMV activity with inhibition rates in the range of 11.6-19.8%.
January 2015
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55 Reads
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3 Citations
Asian Journal of Chemistry
December 2014
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26 Reads
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26 Citations
Phytochemistry Letters
Three new chromones, 5-methoxy-2,2-dimethyl-7-(2-oxopropyl)-2,3-dihydrochromen-4-one (1), 5-methoxy- 2,2-dimethyl-8-(2-oxopropyl)-2,3-dihydrochromen-4-one (2), and 1-(3,4-dihydro-5-methoxy- 2,2-dimethyl-2H-chromen-7-yl)propan-2-one (3), together with four known chromones (4-7) were isolated from the stems of Cassia fistula. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compounds 1-5 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 5 exhibited high anti-TMV activity with inhibition rate of 30.8% at a concentration of 20 mu M. The other compounds also exhibited potential anti-TMV activities with inhibition rates in the range of 15.6-22.1% at the same concentration. (C) 2014 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.
December 2014
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24 Reads
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1 Citation
Asian Journal of Chemistry
A new dihydroxanthone, (1R,2R)-2-hydroxy-6-(hydroxymethyl)-8-methoxy-9-oxo-2,9-dihydro-1H- xanthene-1-carboxylic acid (1) was isolated from the fermentation products of a Phomopsis fungus. Its structure was elucidated by spectroscopic methods. Compound 1 was tested for its cytotoxicity and it showed high cytotoxicity against NB4 and PC3 cell with IC50 values of 4.5 and 3.8 μM.
September 2014
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14 Reads
Asian Journal of Chemistry
A new phenolic amide, (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]-prop-2-enamide (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity and it exhibit potential anti-TMV activity with inhibition rates of 16.2%.
... 16,17 In addition, flavonoids also have been identified as promising anti-TMV agents. Some flavonoids with notable anti-TMV activity, such as flavonoid glycosides from Lasiandra maxim, 18 flavones from leaves of Nicotiana tabacum, 19 chalcones from Desmodium podocarpum, 20 isoflavones from the Pueraria montana, 21 and the like, have also been reported in previous literature. ...
April 2016
Chemistry of Natural Compounds
... For example, in Medicago truncatula, eight GRF genes exhibited lower expression in leaves compared with their expression in other tissues of roots, shoots, and flowers (Bazin et al., 2013). In Chinese cabbage, seven (out of 17) BrGRF genes showed higher expression in young leaves compared to other tissues (Wang et al., 2014). In cucumber (Cucumis sativus), CsGRFs were highly transcribed in ovaries, although CsGRF4 and CsGRF6 exhibited the highest expression in leaves, and CsGRF7 was only detected in roots (Shi et al., 2019). ...
July 2014
Asian Journal of Chemistry
... The genus Garcinia, belonging to the family Clusiaceae or Guttiferae, has a rich source of compounds, including phloroglucinols [1][2][3], xanthones [4][5][6][7][8][9][10][11][12][13], and biflavonoids [14][15][16]. Dauphinol B, a phloroglucinol isolated from G. dauphinensis, showed potent antiplasmodial activity against the Dd2 drug-resistant strain of Plasmodium falciparum, with an IC 50 of 0.8 µM [17]. ...
January 2014
Asian Journal of Chemistry
... Nineteen anthraquinones (281-299) were reported from the arils, leaves, fruits, and flower of C. fistula (Figure 8) [87,89,91,95,98,101,108,110]. A study by Duraipandiyan et al., 2012 [95], on compound 282 isolated from C. fistula flower exhibited cytotoxicity toward COLO 320 DM (human colon cancer cells) and it also induced apotosis at 6.25 mg/mL. ...
July 2014
Asian Journal of Chemistry
... 20 The constituents of Roase Rugosae Flos include polyphenols, flavonoids, essential oils, polysaccharides, pigments and vitamins. [48][49][50][51][52] Among them, quercetin and kaempferol have antidepressant activities and thus may be the main antidepressant constituents of the drug. The water extracts (drugs : water = 1 kg : 10 L) of Roase Rugosae Flos (1 g/kg b.w) were reported to prevent exercise-induced stress in experimental mice models. ...
August 2014
Asian Journal of Chemistry
... isolated from the rhizome of Paris polyphyllavar. in Yunnan, China. Compound 192 showed significant cytotoxic activities against A549 and PC3 cell lines, with IC50 values of 5.8 μM and 3.6 μM, respectively [101]. The anthraquinone derivative eurorubrin 193 ( Figure 14) was obtained from the ethyl acetate extract of the endophytic fungus Eurotium cristatum EN-220 of the seaweed Sargassum thunbergii and tested for its antimicrobial activities against three tested pathogens (E. ...
August 2014
Asian Journal of Chemistry
... Many studies have illustrated the multiresidue quantification of pesticides in tobacco using LC-MS/MS or GC-MS (MS/MS) techniques, coupled with various sample pretreatment techniques such as SPE [6][7][8][9], dispersive solidphase extraction (dSPE) [10,11], matrix solid-phase dispersion (MSPD) [12,13], gel permeation chromatography (GPC) [14,15], and SPME [16]. However, most of these methods suffer from many deficiencies in general, such as the consumption of a large amount of toxic solvent, high cost, and instability or poor repeatability [17]. ...
May 2010
Asian Journal of Chemistry
... Analysis of various organs and tissues of H. chinense identified two new flavones, 6,4′-dimethoxy-8formylflavone and 6,7-dimethoxy-8-acetyl-4′hydroxyflavone, as well as a further five flavones previously identified, of which the inhibitory effect against TMV was up to 31% (Zhou et al., 2015b). ...
October 2015
Chemistry of Natural Compounds
... 52 Around the same time, Ye et al. reported in a separate paper the isolation and identication of the new 3 0 ,4 0 ,5 0 -trihydroxy-5,7-dimethoxyisoavone 31 from the stems of the same species. 53 It is worth mentioning that the three iso-avones share the 3 0 ,4 0 ,5 0 -oxygenation pattern in the B-ring. Three additional new isoavones 32-34 were isolated from the acetone extracts of the leaves of N. tabacum, two of which bear either a methoxycarbonyl-or hydroxymethyl-group at C-8. 54 The structures of these compounds were characterised as 7,4 0dimethoxy-6-hydroxy-8-methoxycarbonylisoavone 33, 7,4 0dimethoxy-6-hydroxy-8-hydroxymethylisoavone 34 and 8,4 0dihydroxy-6,7-dimethoxyisoavone 32. ...
November 2012
Asian Journal of Chemistry
... A new butyrolactone, asperphenol C (229) (Fig.13), was isolated from endophytic fungus Aspergillus Versicolor. It showed inhibitory TMV activity with an inhibition rate of 22.1 %. [109]. ...
October 2015
Asian Journal of Chemistry
