Xu Wang’s research while affiliated with Jilin University and other places

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Publications (19)


Figure 2: Summary of Algorithm(s) Comparation and Tesing Results
Figure 3: ncRNA-based Physical Unclonable Function (PUF) Workflow
Figure 4: Verification and Key Generation Process using RNA-based PUFs Workflow
Parameter Configuration for Different Security Modes
Encryption Time Comparison (s)

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Crypto-ncRNA: Non-coding RNA (ncRNA) Based Encryption Algorithm
  • Preprint
  • File available

April 2025

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1 Read

Xu Wang

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Tin-yeh Huang

In the looming post-quantum era, traditional cryptographic systems are increasingly vulnerable to quantum computing attacks that can compromise their mathematical foundations. To address this critical challenge, we propose crypto-ncRNA-a bio-convergent cryptographic framework that leverages the dynamic folding properties of non-coding RNA (ncRNA) to generate high-entropy, quantum-resistant keys and produce unpredictable ciphertexts. The framework employs a novel, multi-stage process: encoding plaintext into RNA sequences, predicting and manipulating RNA secondary structures using advanced algorithms, and deriving cryptographic keys through the intrinsic physical unclonability of RNA molecules. Experimental evaluations indicate that, although crypto-ncRNA's encryption speed is marginally lower than that of AES, it significantly outperforms RSA in terms of efficiency and scalability while achieving a 100% pass rate on the NIST SP 800-22 randomness tests. These results demonstrate that crypto-ncRNA offers a promising and robust approach for securing digital infrastructures against the evolving threats posed by quantum computing.

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CRYPTO-NCRNA: NON-CODING RNA (NCRNA) BASED EN- CRYPTION ALGORITHM

This paper introduces Crypto-ncRNA, a encryption framework leveraging the dynamic folding mechanisms of non-coding RNA (ncRNA) to address post-quantum cryptography challenges. Capitalizing on ncRNA's intrinsic physical unclonable functions (PUFs) and high conformational entropy, Crypto-ncRNA generates highly stochastic cryptographic keys and ciphertexts. The scheme implements a four-tiered architecture encompassing RNA sequence generation, structural folding, dynamic key derivation, and ciphertext packaging. Experimental results demonstrate Crypto-ncRNA's robust performance in efficiency , throughput, ciphertext randomness, and operational reliability, validated by NIST SP 800-22 randomness tests. Compared to classical algorithms, Crypto-ncRNA exhibits superior entropy and robust security. This study highlights the potential of bio-convergent cryptography for constructing next-generation secure infrastructures.


Figure 1: The full text framework of this study.
Figure 2: Schematic diagram of language generation rules.
Figure 3: Schematic diagram of language learning strategies.
DIALOGUES BETWEEN ADAM AND EVE: EXPLORATION OF UNKNOWN CIVILIZATION LANGUAGE BY LLM

Language serves as an irreplaceable bridge for cultural communication, yet its origins and mechanisms remain largely uncharted territory. The emergence of intelligent agents empowered by LLM and NLP technology offers fresh approaches to investigate language understanding and generation across civilizations. This study constructs "Adam" and "Eve" agents that evolve through multi-scenario dialogues and iterative Q&A strategy learning, thereby elucidating novel language acquisition processes.Our framework reveals fundamental mechanisms of linguistic emergence, offering novel insights into intelligent interaction patterns during language development.


Figure 1: Flowchart for Digital Artwork Generation and Protection
Figure 2: Pollock Drop Painting
Figure 3: Example of style migration results
Watermark Robustness Testing Results
Example of NFT metadata
DIGITAL ART CREATION AND COPYRIGHT PROTECTION IN POLLOCK STYLE USING GANS, FRACTAL ANALYSIS, AND NFT GENERATION

The rapid evolution of artificial intelligence has revolutionized digital art creation, enabling the development of novel methodologies that integrate artistic synthesis with robust intellectual property protection. In this study, we propose an integrated framework that combines Generative Adversarial Networks (GANs), fractal analysis, and wavelet-based turbulence modeling to generate abstract artworks inspired by Jackson Pollock's drip paintings. Beyond emulating Pollock's dynamic style via neural style transfer, our approach quantitatively characterizes the artworks' intrinsic complexity using fractal dimension and turbulence power spectrum metrics. Importantly, we introduce a comprehensive watermark robustness testing protocol that embeds imperceptible digital watermarks into the generated images and rigorously assesses their resilience against common perturbations-including Gaussian noise, JPEG compression, and spatial distortions. By merging these watermarks with NFT metadata, our framework ensures secure provenance and immutability of digital assets. Experimental results demonstrate the feasibility and efficacy of this multifaceted approach in advancing both artistic innovation and reliable digital copyright protection.




A Personalized MOOC Learning Group and Course Recommendation Method Based on Graph Neural Network and Social Network Analysis

October 2024

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105 Reads

In order to enhance students' initiative and participation in MOOC learning, this study constructed a multi-level network model based on Social Network Analysis (SNA). The model makes use of data pertaining to nearly 40,000 users and tens of thousands of courses from various higher education MOOC platforms. Furthermore, an AI-based assistant has been developed which utilises the collected data to provide personalised recommendations regarding courses and study groups for students. The objective is to examine the relationship between students' course selection preferences and their academic interest levels. Based on the results of the relationship analysis, the AI assistant employs technologies such as GNN to recommend suitable courses and study groups to students. This study offers new insights into the potential of personalised teaching on MOOC platforms, demonstrating the value of data-driven and AI-assisted methods in improving the quality of online learning experiences, increasing student engagement, and enhancing learning outcomes.


Octopus Inspired Optimization Algorithm: Multi-Level Structures and Parallel Computing Strategies

October 2024

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74 Reads

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2 Citations

This paper introduces a novel bionic intelligent optimisation algorithm, Octopus Inspired Optimization (OIO) algorithm, which is inspired by the neural structure of octopus, especially its hierarchical and decentralised interaction properties. By simulating the sensory, decision-making, and executive abilities of octopuses, the OIO algorithm adopts a multi-level hierarchical strategy, including tentacles, suckers, individuals and groups, to achieve an effective combination of global and local search. This hierarchical design not only enhances the flexibility and efficiency of the algorithm, but also significantly improves its search efficiency and adaptability. In performance evaluations, including comparisons with existing mainstream intelligent optimisation algorithms, OIO shows faster convergence and higher accuracy, especially when dealing with multimodal functions and high-dimensional optimisation problems. This advantage is even more pronounced as the required minimum accuracy is higher, with the OIO algorithm showing an average speedup of 2.27 times that of conventional particle swarm optimisation (PSO) and 9.63 times that of differential evolution (DE) on multimodal functions. In particular, when dealing with high-dimensional optimisation problems, OIO achieves an average speed of 10.39 times that of DE, demonstrating its superior computational efficiency. In addition, the OIO algorithm also shows a reduction of about 5%5\% in CPU usage efficiency compared to PSO, which is reflected in the efficiency of CPU resource usage also shows its efficiency. These features make the OIO algorithm show great potential in complex optimisation problems, and it is especially suitable for application scenarios that require fast, efficient and robust optimisation methods, such as robot path planning, supply chain management optimisation, and energy system management.


CINNAMOROLL FLY: PHYSICAL SIMULATIONE

September 2024

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67 Reads

The cartoon image of Cinnamoroll achieves flight by synchronous flapping of both ears. Although this setting is exaggerated and anthropomorphic, it is worthwhile to analyse its flight mechanism from the perspective of physics. In this paper, we investigate the lift force generated by the synchronised flapping of both ears through aerodynamic and hydrodynamic theories and numerical simulations, and evaluate the feasibility of flight. Using Python programming language, this paper simulates the relationship between the lift force and the airflow velocity, flapping frequency, airflow time variation and other factors. The simulation results show that binaural synchronised flapping can generate sufficient lift to support flight for a specific flapping frequency and airflow velocity. This study provides scientific support for the flight mechanism of fictional organisms and bionic insights for the design of micro air vehicles.



Citations (9)


... Figure 4C reveals that after reducing the mass ratio of SIM to silica nanoparticles organic solvents, DCM, chloroform, ethanol, and DMF were utilized. Figure 4A shows that out of all the solvents tested, DCM (polarity index = 3.1) [45,46] had the most remarkable drug loading capacity at 22.49%, followed by chloroform (polarity index = 4.1) [47,48] and ethanol (polarity index = 4.3) [35,49]. In contrast, DMF (polarity index = 6.4) [50,51] had the lowest SIM loading at 2.45%. ...

Reference:

Simvastatin loaded surface-decorated 3D-dendritic mesoporous silica nanoparticles for enhanced antihyperlipidemic activity: in vitro and in vivo appraisal
Improvement of polarity-based solvent system for countercurrent chromatography in the guidance of solvent selectivity: n-hexane/ethyl acetate/ alcohol solvents/water as an example
  • Citing Article
  • September 2024

Journal of Chromatography A

... This technique effectively enhances gas exchange, positioning it as a viable alternative strategy. 3,4 In recent decades, extensive research has been conducted on the implementation of NIPPV in neonates, particularly EPT and ELBW infants. Evidence suggests that NIPPV may decrease the need for invasive ventilation, lower ventilator-related complications, shorten hospital stays, and potentially enhance survival rates, in comparison with IPPV. ...

An integrative pharmacology-based study on the efficacy and mechanism of essential oil of Chaihu Guizhi Decoction on influenza A virus induced pneumonia in mice
  • Citing Article
  • August 2024

Journal of Ethnopharmacology

... For instance, The CMM pair with the strongest positive correlation is Jujubae Fructus (Dazao) and Zingiberis Rhizoma Recens (Shengjiang) (r 0.55), suggesting that this combination may exhibit synergistic effects. Through literature review, we found that both of these CMMs are simultaneously present in several TCM formulas, including Chaihu Guizhi Decoction (Zhao et al., 2024), Da-Chai-Hu-Tang Formula (Duan et al., 2024), and Zhi-Gan-Cao-Tang . This combination has the effects of harmonizing the defensive and nutritive qi, regulating the spleen and stomach, warming the meridians, and promoting circulation (Liao et al., 2023). ...

UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction
  • Citing Article
  • October 2023

Journal of Ethnopharmacology

... While these techniques have demonstrated promise-for instance, improved detection of figurative expressions in Chinese medical documents-they remain limited in their ability to handle the profound cultural embedding of TCM metaphors [24], [25]. Consequently, new strategies are needed to systematically address TCM's multilayered conceptual scheme, particularly in bridging abstract notions (e.g., Yin deficiency) with empirical or mechanistic frameworks [26], [27]. ...

Novel Medical Question and Answer System: Graph Convolutional Neural Network Based with Knowledge Graph Optimization
  • Citing Article
  • April 2023

Expert Systems with Applications

... Nevertheless, in several of these foods, we not only find B-type procyanidins but also A-type procyanidins with an ether bond at C2-O-C7. The evidence indicates that acid depolymerization or acidolysis is effective only in type B procyanidins, so foods such as cinnamon, which rich are in A-type procyanidins, would not be as useful in that case [38][39][40]. Considering these data, it is possible to evaluate the use of various foods as rich sources of procyanidins. It is important to highlight that the use of avocado peel to obtain these resources gives it a new value as The yields of the hemisyntheses after CPC purification are shown in Table 2. ...

A Rapid and Practical Prediction Method for the Arizona Solvent System Family (HEMW) of High Speed Countercurrent Chromatograph
  • Citing Article
  • July 2020

Journal of Chromatography A

... Using HPIC to determine the monosaccharide composition of PMPS-A 1 (Figure 3D), the results indicate that PMPS-A 1 was composed of glucose and fructose (glucose: fructose, 7:5). This is different from the polysaccharide purified by Du et al. [35] from Puerariae thomsonii, which consists entirely of glucose. This may be caused by different varieties ...

Isolation, purification, structural analysis and biological activities of water-soluble polysaccharide from Glehniae radix
  • Citing Article
  • May 2019

International Journal of Biological Macromolecules

... 13 C-NMR (DMSO-d 6 , 125 MHz) δ C 182.3 (C-4), 164.6 (C-7), 164.1 (C-2), 161.9 (C-5), 157.8 (C-9), 148.7 (C-3′, C-5′), 140.3 (C-4′), 120.9 (C-1′), 104.8 (C-2′, C-6′), 104.2 (C-10), 104.1(C-3), 99.3 (C-6), 94.7 (C-8), 56.8 (3′-OCH 3 , 5′-OCH 3 ). The compound was identified as tricin (Fig. 2) by 1 H and 13 C-NMR analysis (Table 2) in comparison with the literature data (Kim et al. 2009;Liu et al. 2018;Wang et al. 2016). ...

Chemical Constituents of Lonicerae Japonicae Flos
  • Citing Article
  • September 2016

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

... Androseptoside A (63) [33] has been isolated from L. nigru L. species. (47)(48)(49)(50)(51)(52)(53)(54)(55)(56)(57)(58)(59)(60)(61)(62)(63). ...

Nortirucallane A, a new tirucallane-type nortriterpenoid isolated from Lonicerae japonicae flos
  • Citing Article
  • March 2017

... Ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry (UHPLC-QQQ-MS) operated in multiple reaction monitoring (MRM) mode is an effective quantification method owing to its well-known high sensitivity and specificity, which could avoid the interference from the background matrix [7][8][9]. It has been successfully utilized to quantify bioactive components in the complex systems [10][11][12][13][14][15]. In the current study, therefore, an UHPLC-QQQ-MS method was developed to simultaneously quantify 43 bioactive components in the Chinese herbal spirit samples produced by year 2014 and 2018, and their concentrations in different peoduction years were also compared. ...

Qualitative and quantitative analysis of the chemical constituents in Mahuang-Fuzi-Xixin decoction based on high performance liquid chromatography combined with time-of-flight mass spectrometry and triple quadrupole mass spectrometers: Qualitative and quantitative analysis
  • Citing Article
  • May 2016

Biomedical Chromatography