Xiaohui Song's research while affiliated with Tsinghua University and other places

Publications (8)

Article
Full-text available
Purpose: To investigate the visual quality after femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) with the implantation of an extended depth-of-focus (EDOF) intraocular lens (IOL) TECNIS Symfony. Setting: Eye Center, the Second Affiliated Hospital of Zhejiang University, Zhejiang, China. Des...
Article
Purpose: To compare the visual outcomes and optical quality of 2 presbyopia-correcting intraocular lenses (IOLs) with those of a monofocal IOL. Settings: Eye Center, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China. Design: Prospective, nonrandomized, examiner-blinded cohort study. Method:...
Article
Full-text available
Purpose: To compare the clinical outcomes of echelette extended range of vision (ERV) and diffractive bifocal intraocular lenses (IOLs). Methods: This is a prospective, consecutive, nonrandomized clinical trial. Seventy-three eligible patients (109 eyes) received the implantation of echelette ERV IOL (Tecnis Symfony ZXR00) or diffractive bifocal...
Article
Purpose To compare the outcomes between femtosecond laser–assisted cataract surgery (femtosecond group) and conventional phacoemulsification cataract surgery (conventional group) in patients with hard nuclear cataract. Setting Eye Center, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China. Design Prospective co...
Data
PRISMA-checklist in this meta-analysis. (DOC)
Article
Full-text available
Purpose To compare dry eye after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK) for correcting myopia. Methods CENTRAL, Embase and PubMed were searched in November 2016. All randomized controlled trials (RCTs) and prospective cohorts that compared dry eye after SMILE with FS-LASIK were selected. Result...
Data
Search strategy of PubMed. (DOCX)
Article
Toxic lipofuscin in the retinal pigment epithelium (RPE)is implicated in blindness in age-related macular degeneration (AMD) or recessive Stargardt disease patients. In this study, we identified a novel fluorescent lipofuscin component in human and bovine RPEs. Using one- and two-dimensional NMR and mass spectrometry, we confirmed the structure of...

Citations

... Therefore, one possible explanation for these results was the application of FLACS. Xu et al [39] reported that FLACS presented a significantly lower total HOAs and spherical aberration, because femtosecond laser was able to accurately control the size and shape of the capsulotomy and deliver a more centered IOL, resulting in lower internal HOAs and higher visual quality in comparison with conventional phacoemulsification. ...
... Compared with former generations of presbyopia-correcting IOLs, modern diffractive bifocal, trifocal, and EDOF IOLs have shown beneficial effects on spectacle independence and patient satisfaction. 15,[27][28][29] Monovision with monofocal IOLs, which can provide some level of presbyopia correction, has limitations, however, with some patients showing low tolerance due to reduced binocularity and stereopsis, especially with traditional monovision, and relatively low and unsustainable spectacle independence. [30][31][32][33][34] The relatively high usage of monovision with monofocal IOLs in the present study and the relatively low adoption rate of presbyopia-correcting IOLs throughout the study period were somewhat surprising. ...
... The bimodal defocus curve also provided better near vision. The defocus curve shape is similar to that of Chang et al. (13,21). Carones et al. found that the ZXR00 IOL has a higher tolerance for astigmatism than other types of bifocal and trifocal intraocular lens, which is related to the design of the ZXR00 IOL 1.6 mm large central apertures (22). ...
... Femtosecond laser cataract surgery applications have expanded to include not only ordinary cases but also challenging ones [16,17]. Opinions vary regarding the role of femtosecond laser technology in the management of mature intumescent cataracts. ...
... Artificial tears, physical therapy of meibomian gland dysfunction, punctal plugs and other treatments are used to relieve the symptoms caused by DED after SMILE (3). Nevertheless, according to the literature, dry eye symptoms persist for months or even years in a lot of patients (4). ...
... Accumulated AtRal, and A2E along with its subtypes induce the formation of singlet oxygen, and since it is highly capable of oxidizing DNA, it is considered as a major DNA oxidizer (Cadet and Wagner, 2013). Importantly, A2E is a fluorescent component of insoluble lipofuscin within the RPE cells, and thus can act as a permanent inducer of ROS production in RPE cells (Ben-Shabat et al., 2002;Różanowska et al., 2012;Wu et al., 2014b). Since UV light does not reach the retina of the normal adult eye, it is the blue region of the visible light that induces the production of singlet oxygen by A2E, and thus it is considered as the initiator of blue light-induced apoptosis in RPE cells (Różanowska et al., 2012;Sparrow et al., 2000). ...