Wolfgang Uter's research while affiliated with Friedrich-Alexander-University of Erlangen-Nürnberg and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (37)
Assessing the risk of bias (ROB) of studies is an important part of the conduct of systematic reviews and meta-analyses in clinical medicine. Among the many existing ROB tools, the Prediction Model Risk of Bias Assessment Tool (PROBAST) is a rather new instrument specifically designed to assess the ROB of prediction studies. In our study we analyze...
Nonmelanoma skin cancer (NMSC) is the most common cancer type in Western industrialized countries. However, research into the knowledge and awareness in the general population regarding NMSC is still scarce. This qualitative study aims to fill this research gap. Face-to-face, semi-structured interviews with 20 individuals aged 55–85 years were cond...
Background:
Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society.
Objectives:
To present the sensitization frequencies...
Importance
The common use of isothiazolinones as preservatives is a global cause of allergic contact dermatitis. Differences in allowable concentrations of methylisothiazolinone (MI) exist in Europe, Canada, and the US.
Objective
To compare the prevalence of positive patch test reactions to the methylchloroisothiazolinone/methylisothiazolinone (MC...
This systematic review, conducted according to the PRISMA guidelines, focuses on genotoxicity of oxidative hair dye precursors. The search for original papers published from 2000 to 2021 was performed in Medline, Web of Science, Cochrane registry, Scientific Committee on Consumer Safety of the European Commission and German MAK Commission opinions....
Introduction:
Hairdressers are exposed to wet work and manifold allergens at work, rendering exposure complex and the aetiology of occupational hand eczema often multifactorial in this occupational group.
Objectives:
To identify exposure patterns associated with increased risk of hand eczema in hairdressers.
Methods:
All hairdressers graduatin...
The European baseline series was last updated in 2019. This article discusses the reasoning behind a further iteration of the series for 2023.
Background:
Various products are available for lightening hair. There are no data on which applications are actually used in hairdressing, impeding proper estimation of actual exposure and necessary preventive measures.
Objectives:
To assess information about availability, usage and formulation of lightening preparations in the German hairdressi...
Background:
The burden of occupational hand eczema in hairdressers is high, and (partly strong) allergens abound in the hair cosmetic products they use.
Objectives:
To systematically review published evidence concerning contact allergy to an indicative list of active ingredients of hair cosmetics, namely, p-phenylenediamine (PPD), toluene-2,5-di...
Objectives:
To review recent epidemiological studies investigating carcinogenic or reprotoxic effects among hairdressers who seem to be at greater risk for systemic adverse effects of chemicals released from hair care products than consumers.
Methods:
A systematic review according to the PRISMA-P guidelines was performed and included studies pub...
Background:
Compliance with glove use and safe work practices are important factors in primary prevention of occupational hand eczema (OHE) in hairdressers.
Objective:
To assess the risk OHE and compliance with skin protective measures in hairdressers trained before and after implementation of a nationwide skin protection program in Danish haird...
The safety assessment of cosmetics considers the exposure of a ‘common consumer’, not the occupational exposure of hairdressers. This review aims to compile and appraise evidence regarding the skin toxicity of cysteamine hydrochloride (cysteamine HCl; CAS no. 156-57-0), polyvinylpyrrolidone (PVP; CAS no. 9003-39-8), PVP copolymers (CAS no. 28211-18...
Background
Occupational hand eczema (OHE) is common in hairdressers, and many leave the trade because of the disease. However, the exact impact of OHE on career length is unknown.
Objective
To assess the effect of OHE on career length and risk factors associated with leaving the trade because of OHE in hairdressers followed-up for up to 35 years....
Rising incidences of cutaneous melanoma have fueled the development of statistical models that predict individual melanoma risk. Our aim was to assess the validity of published prediction models for incident cutaneous melanoma using a standardized procedure based on PROBAST (Prediction model Risk Of Bias ASsessment Tool). We included studies that w...
Background:
Continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing the value of included allergens.
Objectives:
To present results of current EBS patch testing, obtained in 53 departments in 13 European countries during 2019 and 2020.
Methods:
Anonymised or pseudony...
Rising incidences of cutaneous melanoma have fueled the development of statistical models that predict the individual melanoma risk. Our aim was to assess the validity of published prediction models for incident cutaneous melanoma using a standardized procedure based on PROBAST (Prediction model Risk Of Bias ASsessment Tool). We included studies th...
Background:
Essential oils (EOs) are widely used in cosmetics, perfumes, massage fluids, aroma therapy, and natural medicine. Some essential oils contain contact sensitizers.
Objectives:
To describe the frequency of sensitization to EOs in dermatitis patients presenting in skin clinics including concomitant reactions, to evaluate the EO patch te...
Introduction:
Exposure to hazardous chemicals released during hairdressing activities from hair care products puts hairdressers at risk of adverse health effects. Safety assessments of hair products are mainly focused on consumers, but exposure for professional hairdressers might be substantially higher.
Objective:
To identify and assess availab...
Objective
To review the literature on respiratory effects of persulfate salts (PS) or hair bleaches in hairdressers and animal models exploring mechanisms behind PS-induced asthma.
Methods
A systematic review according to the PRISMA guidelines was performed. Studies published from 2000 to July 2021 that fulfilled predefined eligibility criteria we...
Background:
Relevant nickel and cobalt release from hairdressing tools has recently been evidenced. Comparable data are not available for tools used in beauty salons.
Objectives:
Screening of beauty tools for nickel and cobalt release.
Methods/materials:
Three hundred eight beauty tools were tested in seven beauty salons located in two North-G...
More than twenty-five years ago, the Global Solar UV index (UVI) was introduced as a simple means of visualizing the intensity of ultraviolet radiation and to alert people to the need for sun protection. In our survey, among directors of 436 kindergartens in southern Germany we investigated the level of awareness and knowledge about the UVI as well...
Contact dermatitis is a common disease, caused by repeated skin contact to contact allergens or irritants, resulting in allergic contact dermatitis (ACD) and/or irritant contact dermatitis. Attempts have been made to identify biomarkers to distinguish irritant and allergic patch test reactions, which could aid diagnosis. Some promising candidates h...
Background:
In 2019, a number of allergens (haptens), henceforth, 'the audit allergens,' were considered as potential additions to the European baseline series (EBS), namely, sodium metabisulfite, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, imidazolidinyl urea, Compositae mix II (2.5 or 5% pet), linalool hydroperoxides (lin-OOH), limonene...
Current cosmetic regulations primarily focus on protecting consumers, not the professional user who is subjected to a partly different, and certainly more intense exposure to hazardous substances. Against this background, the present systematic review aims to compile and appraise evidence regarding skin toxicity of 2-hydroxyethyl methacrylate (HEMA...
Hairdressers are at high risk of developing occupational hand eczema. Opinions on the health and safety concerns of non-food consumer products, such as cosmetics and their ingredients, consider the exposure of a 'common consumer', which may not account for occupational exposure of hairdressers. As result, there is a parlous scenario in which seriou...
Transparent and accurate reporting is essential to evaluate the validity and applicability of risk prediction models. Our aim was to evaluate the reporting quality of studies developing and validating risk prediction models for melanoma according to the TRIPOD (Transparent Reporting of a multivariate prediction model for Individual Prognosis Or Dia...
Background
Hairdressers are commonly affected by hand eczema (HE), due to skin hazardous exposure such as irritants and allergens in the work environment.
Objective
To give an overview of the current prevalence, incidence, severity as well as the pattern of debut and the contribution of atopic dermatitis on HE in hairdressers.
Methods
A systemati...
More than twenty-five years ago the Global Solar UV index (UVI) has been introduced as a simple means of visualizing the intensity of ultraviolet radiation and to alert people to the need for sun protection. In our survey among directors of 436 kindergartens in southern Germany we investigated the level of awareness and knowledge about the UVI as w...
Introduction:
Hairdressers constitute a major subgroup in the service sector. They are exposed to various substances hazardous for skin, airways or systemically. Accordingly, skin and other occupational diseases are common. The present systematic review will compile and appraise evidence regarding skin, systemic and airways toxicity of an indicati...
This chapter summarises all relevant aspects of patch testing, closely following recommendations outlined in a recent European, and a German S3 guideline on diagnostic patch testing with contact allergens and medicinal products (drugs). Patch testing is indicated in patients suspected of suffering, or having been suffering, from delayed-type hypers...
Background
The contact allergy prevalences in patch tested patients are usually higher than those in the population, owing to morbidity-driven selection.
Objectives
To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia).
Methods
Between August 2008 and Octo...
Kontaktallergie (Sensibilisierung) und daraus resultierende allergische Kontaktdermatitis (ACD) sind von erheblicher Tragweite aus Sicht des Gesundheitswesens. Für die vorliegende Übersichtsarbeit hierzu wurden alle passenden Artikel aus dem Zeitraum 2018–2019 per systematischer Suche in Medline und Web of Science<sup>TM</sup> ermittelt; außerdem w...
Background
Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or the cumulative exposure to various weaker physical and/or chemical irritants.
Objectives
To describe characteristics of patients with ICD in the population patch tested in the European Surveillance System on Contact Allergies (ESSCA; w...
Existing criteria for inclusion in the European baseline series are summarised. Additional criteria are developed to aid decision making where the current criteria do not yield an unequivocal result. These include a consideration of whether an allergen (hapten) is better placed in a special series and the frequency with which an allergen cross‐reac...
(1) Background: Different sources of information are used by the population regarding skin cancer prevention. The pertinent quality of information that can be retrieved via an internet search engine needs assessment; (2) Methods: Four topical searches in common language were entered into Google™. The first 200 “hits” were stored for further use. El...
Citations
... Procaine hydrochloride may also be tested as 1% pet. In the Medicament Series, there is an additional caine mix IV 10% pet (lidocaine 5%, prilocaine hydrochloride 2.5%, amylocaine hydrochloride 2.5%) [13,49,56]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/606682602274816-1521655812168_Q64/Stephen-Wilkinson-2.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272381369384973-1441952187221_Q64/Margarida-Goncalo.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272950439968770-1442087864208_Q64/Olivier-Aerts.jpg)
... Only with regard to the more broadly patch-tested surfactant CAPB could a significantly increased risk of contact allergy in hairdressers be identified. This suggests, in line with results from other hairdressing cosmetic chemicals [109], that an estimated frequency of use by consumers is insufficient to determine hairdressing exposure. Thus, current standards of risk assessment do not effectively address the occupational risks associated with the use of hair cosmetics by hairdressers. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/316619388063744-1452499352721_Q64/Swen-John-2.jpg)
... 4,5 Recent studies reported increased micronucleus frequencies in hairdressers, 19,48 a population heavily exposed to hairdressing products including oxidative hair dyes. 49 In addition, significantly higher DNA damage scores were found among hairdressers compared to controls, based on the comet assay performed on blood samples. 50 Nevertheless, linking experimental results with epidemiological studies is difficult owing to, among other things, the kinetic properties of oxidative hair dye precursors. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/754826275209216-1556976016440_Q64/Cara-Symanzik.jpg)
... A recent study examined the long-term impact of hand dermatitis using data from a Danish prospective cohort study of hairdressers graduating from 1985 to 2007 [46,47]. The authors found that hand dermatitis began early in one's career, during apprenticeship. ...
Reference: Occupational Hand Dermatitis
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272461698695171-1441971339732_Q64/Claus-Zachariae.jpg)
... The update included the forward snowballing technique, which was applied on [21] and two other previously published systematic reviews on the same topic [22,23], and an electronic literature search in PubMed using the same search string as in [21]. Details on the study selection and eligibility criteria were published previously in a report describing the ROB of melanoma prediction studies based on the consensus ROB rating of the rater team [24]. with systematic reviews and ROB assessments. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/1184235385819146-1659355126938_Q64/Sonja-Mathes-2.jpg)
... Allergy (ESSCA) 3 and an audit of the proposed changes once implemented 4,5 confirm that the existing haptens within the EBS occur with a frequency to merit their continued inclusion. The continued inclusion of methyldibromo glutaronitrile (MDBGN) has, however, been questioned due to a lack of current clinical relevance. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/277529874190345-1443179686595_Q64/Andrea-Bauer-4.jpg)
... 13,14,15 In addition, hairdressers could also be at increased risk due to higher exposure to hairdressing chemicals at work compared to consumers. 16,17 Increased risk of bladder cancer among hairdressers in comparison to the general population was noted in the study from New Zealand. 18 Carcinogenicity could be the result of a genotoxic mode of action. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/987197419294720-1612377614046_Q64/Sanja-Kezic-3.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272333592068105-1441940796210_Q64/Henk-F-Molen.jpg)
... 135 Certainly, this is also a very useful measure of primary prevention of airborne (skin and inhalatory) exposure, although this has not yet been confirmed by actual exposure studies. 134 ...
... Micro-needling made from stainless steel repeatedly puncturing the skin may release Ni [33]. Ni and Co is released in allergology-relevant amounts from beauty tools [34] and metal hairdressers' tools [35,36]. The European Union established a limit of 0.2 μg/cm 2 /week Ni release for the items by the Directive in 2004 [37]. ...
... Mask [54] Mechanical irritation Allergic hapten Acne Vulgaris Mask [42] Alteration in the local skin environment, e.g., the microbiome, temperature, moisture, mechanical follicular blocking Irritant contact dermatitis is an inflammatory reaction that develops when keratinocytes are destroyed due to the toxicity of the contact source, resulting in the release of lysosomes and different cytokines [74][75][76] (Figure 1). By stimulating the skin above a specific threshold, irritant contact dermatitis enables the development of non-specific inflammation, even at the time of initial exposure. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/359036257095682-1462612322938_Q64/Jakob-Schwensen-2.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/331215946174469-1455979443425_Q64/Jacob-Thyssen.jpg)
