Wojciech Pawliszak's research while affiliated with Nicolaus Copernicus University and other places

Publications (43)

Article
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Communication with patients regarding oncology-related aspects is a challenging experience and requires a high level of skill from the interlocutors. The aim of this study was to verify the influence of religion/spirituality in oncological settings from the health professionals’ perspectives in Poland. It assessed the role of religion/spirituality...
Article
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The COVID-19 pandemic has impacted religion and faith in different ways. Numerous restrictions have been implemented worldwide. Believers are in conflict with authorities’ warnings that gatherings must be limited to combat the spread of the virus. Religion has always played a role of the balm for the soul, and the regular religious participation is...
Article
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The development of anticancer therapies that involve natural drugs has undergone exponential growth in recent years. Among the natural compounds that produce beneficial effects on human health, polyphenols have shown potential therapeutic applications in cancer due to their protective functions in plants, their use as food additives, and their exce...
Article
Background: Type 2 neurological complications of coronary artery bypass grafting (CABG) include postoperative cognitive dysfunction (POCD) and delirium. Although relevant clinically, they are rarely properly recognized outside of dedicated research setting, as their identification is complex and time-consuming. The aim of this study was to examine...
Article
Background: Neuropsychiatric complications of surgical coronary revascularization are inconspicuous but frequent and clinically relevant. So far, attempts to reduce their occurrence, such as the introduction of off-pump coronary artery bypass (OPCAB) grafting method, have not brought the desired results. The aim of this trial was to determine whet...
Article
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Objectives: Surgical re-exploration due to postoperative bleeding that follows coronary artery surgery is associated with significant morbidity and mortality. The aim of this study was to assess a relationship between re-exploration, major postoperative complications, in-hospital mortality and mid-term outcomes in patients following coronary surge...
Article
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Background: Considerable attention has been focused over the past several years on the protein Z (PZ) system. However, little is known about the role of auto-antibodies to PZ (anti-PZ) in cardiac surgery patients. Aim: In the present pilot study, we investigated plasma levels of anti-PZ in patients undergoing off-pump coronary artery bypass (OPCAB)...
Article
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Objectives Surgical ablation for atrial fibrillation (AF) performed at the time of other valvular- or non-valvular cardiac procedure is a mainstay of therapy; yet the data regarding its impact on remote survival are sparse. Current investigation aimed to evaluate late survival in patients undergoing mitral valve (MV) surgery with concomitant surgic...
Article
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Neurological injury is a frequent and important complication of coronary artery bypass grafting (CABG). Several risk factors for this type of sequela have been identified, among them aortic arch atherosclerosis. Our previous study indicated that atherosclerotic burden in coronary arteries may likewise predict postoperative neurological complication...
Article
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Introduction Coagulation factor XIII (FXIII) is the zymogen precursor of an active transglutaminase (FXIIIa); it circulates in blood as a heterotetramer consisting of 2 catalytic A subunits (FXIII-A) and 2 noncatalytic B subunits (FXIII-B). In the presence of thrombin and calcium, the A subunits are released and activated. The enzyme plays a crucia...
Conference Paper
Introduction Coronary artery disease (CAD) is the leading cause of death in patients with diabetic mellitus (DM). Coronary artery bypass (CABG) surgery with arterial conduits is considered optimal as a treatment of CAD for diabetic patients. Studies have demonstrated the long-term benefit of bilateral internal mammary artery (BIMA) use for CABG for...
Article
To understand the coagulation changes after off-pump coronary artery bypass (OPCAB) surgery, we evaluated the procoagulant activity of microparticles (MPs) and microparticles exposing tissue factor (MPs-TF), together with the levels of total tissue factor (TF), protein Z (PZ), protein Z-dependent protease inhibitor (ZPI), and factor X (FX) before (...
Article
Objectives: To investigate the potential beneficial effects of posterior pericardial drainage in patients undergoing heart surgery. Methods: Multiple online databases and relevant congress proceedings were screened for randomized controlled trials assessing the efficacy and safety of posterior pericardial drainage, defined as posterior pericardi...
Article
Controversies remain on the increased rate of neurological events after small thoracotomy mitral valve surgery attributed to endoaortic balloon occlusion (EABO). Systematic literature search of databases identified 17 studies enrolling 6,643 patients comparing safety and effectiveness of EABO versus transthoracic clamp. In a meta-analysis, there wa...
Article
Objectives: To assess safety and effectiveness of different periprocedural antithrombotic strategies in patients receiving long-term oral anticoagulation and undergoing coronary angiography with or without percutaneous coronary intervention (PCI). Methods: Studies comparing uninterrupted oral anticoagulation (UAC) with vit. K antagonists vs inte...
Article
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Background Off‐pump coronary artery bypass (OPCAB) has been shown to reduce the risk of neurologic complications as compared to coronary artery bypass grafting performed with cardiopulmonary bypass. Side‐clamping of the aorta while constructing proximal anastomoses, however, still carries substantial risk of cerebral embolization. We aimed to perfo...
Article
OBJECTIVES Coronary artery bypass grafting (CABG) remains the standard of care in patients with extensive coronary artery disease. Yet the use of cardiopulmonary bypass (CPB) is believed to be a major determinant of perioperative morbidity. Novel techniques are sought to tackle the shortcomings of CPB, among them off-pump coronary artery bypass (OP...
Article
Objectives: To assess the benefits and risks of off-pump coronary artery bypass (OPCAB) versus coronary artery bypass grafting (CABG) through a meta-analysis of randomized controlled trials (RCTs), and to investigate the relationship between outcomes and patient risk profile. Methods: PubMed, Embase, the Cumulative Index of Nursing and Allied He...
Article
Full-text available
Background: Current guidelines recommend culprit-only revascularisation (COR) in haemodynamically stable patients with ST-segment elevation myocardial infarction (STEMI) and multivessel (MV) disease. Contrarily, growing body of evidence available from recent randomised controlled trials (RCTs) demonstrates improved outcomes with complete MV-percut...
Article
Sternal wound infections are serious postoperative complications that increase the length of hospital stay and healthcare costs. The benefit of implantable gentamicin-collagen sponges in reducing sternal wound infections has been questioned in a recent multicenter trial. We aimed to perform a comprehensive meta-analysis of studies assessing the eff...
Article
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Objectives. Postoperative cognitive dysfunction (POCD) is an important neuropsychiatric complication of coronary artery bypass grafting (CABG). It is most likely caused by microembolic brain damage and affects domains of attention, memory, executive functions and dexterity. In order to achieve better neuroprotection, surgeons introduced some advant...
Article
In spite of the progress in medicine post operative cognitive deficiency (POCD) remains an important clinical problem. Since the introduction of cardiac surgery there have been frequent reports of its adverse neurological outcomes. Recent technological advances have contributed to a lesser occurrence of clinically evident complications such as coma...
Article
Heart disease operative treatment can contribute to the occurrence of a number of complications. Introducing new techniques has reduced this risk, though it has not eliminated it completely. A cardio-surgical procedure is a traumatic experience having a strong effect on an organism's homeostasis, whereas the procedure-related trauma brings about a...
Article
We present a case of a 67-year-old female patient with diagnosed papillary fibroelastoma (PFE) of the aortic valve. Eight months before the tumour discovery a non-ST segment elevation myocardial infarction without essential coronary artery restriction was diagnosed. The tumour was excised (during the aortotomy under cardiopulmonary bypass at system...
Article
Full-text available
Iatrogenic perimembranous ventricular septal defect is a rare complication after surgical replacement of the aortic valve, and so transcatheter closure of such a defect is not a routine procedure. We report the successful closure of an iatrogenic perimembranous ventricular septal defect which occurred after the replacement of the aortic valve and a...
Article
Transmyocardial laser revascularization (TMLR) is a modem approach in the management of coronary artery disease. It can be considered as a method of choice in some cases unsuitable for coronary angioplasty or bypass grafting. Transmyocardial laser revascularization is expected to relieve angina and to improve patient quality of life and survival. T...
Article
A case of 46-year-old patient with unstable angina and tumor localized in left lung is presented. The patient was operated through left antero- lateral thoracotomy. Left lower lobectomy was done and afterwords LIMA graft was implanted to LAD on beating heart. Concomitant radical resection of pulmonary cancer and myocardial revascularization without...

Citations

... In this sense, an upward trend of interest in this field can be observed, as a very significant increase in the number of publications has been found since 1999, particularly after 2009 [6]. This is equally being reflected in the importance researchers are placing on the psychosocial aspects of religion and spirituality (R/S) within medical practice and healthcare settings [7][8][9][10][11], due to their influence on people's physical and mental health. ...
... Just like the experience of many people worldwide, religious creeds and beliefs not only allow us to understand but they influence the meaning of many events occurring in everyone's life. Faith or broadly understood spirituality is a force that helps to overcome the mental crisis as well as facilitate adaptation to the disease or the restrictions resulting from it (Kowalczyk et al., 2020). The faith of many Filipinos was tested but remained powerful at all costs. ...
... In this regard, polyphenols, a natural compounds of plant origin, represent promising approaches for either single or combined anti-tumor therapies, displaying greater efficacy and less toxicity [23,24]. In vitro and in vivo reports, as well as human studies, corroborate polyphenols' protective effects against neurodegenerative and inflammatory chronic diseases, obesity, diabetes [25][26][27][28] and also tumor development [29][30][31]. ...
... Another two meta-analyses, however, reported that octogenarians in the OPCABG group had a reduced inhospital death rate. 8,9 The discrepancy in these conclusions may be due to differences in endpoint definitions. Mauldon et al. 35 conducted a metaanalysis to investigate the effect of age on outcomes after OPCABG or CCABG. ...
... The stress response to cardiac surgery has also been investigated as a possible factor in the development of DNR. In addition, cardiopulmonary bypass surgery may, to a certain extent, cause the formation of microemboli in the brain, cerebral hypoperfusion, decreased cerebral oxygen saturation, release of inflammatory factors and fluctuations in body temperature, and other pathological and physiological changes [19]. However, the specific mechanism of DNR and its relationship with CPB have not been clarified. ...
... Heart bypass surgery is one of the most widely performed major surgeries in the world. Despite the introduction of neuroprotective operating techniques such as the offpump coronary artery bypass (OPCAB) method and its state-of-the-art modifications, recovery from this procedure is still frequently impaired by neurological complications [1]. These have a wide range of manifestations and can be categorized into either type 1, which is associated with major focal deficits, or type 2, which includes postoperative delirium (PD) and early postoperative cognitive dysfunction (ePOCD) [2]. ...
... Po pierwsze, biorąc pod uwagę fakt, że pacjenci z aCL są bardziej narażeni na rozwój powikłań zakrzepowych, cenną obserwacją byłaby ocena wszystkich składników układu białka Z: PZ, ZPI, FX i przeciwciał anty-PZ [6]. Chociaż przeciwciała anty-PZ są rzadko obserwowane we krwi pacjentów ze zdiagnozowanymi chorobami sercowo-naczyniowymi [5,7], taka analiza mogłaby odpowiedzieć na pytanie, czy ten PZ is a cofactor of ZPI, which in fact, increases its anticoagulant properties a thousand fold [3]. ...
... Many studies support the use of concomitant valve replacement (VR) and BRFA in the treatment of older patients with valve disease combined with AF [7,8]. However, some studies suggest there is little or no benefit from concomitant BRFA for a proportion of these patients [9,10]. Many surgeons are still reluctant to perform concomitant AF ablation in older patients because of concerns that this procedure may increase overall surgical risk. ...
... There is not much research with this biomarker in cardiac surgery, and the results are contradictory. Szwed K. compared several biomarkers suitable for cardiac surgery and did not find Nf-H elevation in patients with cognitive dysfunction [26]. Saller T. observed elevated neurofilament levels for patients with delirium after cardiac surgery [27]. ...
... CHD, one of the leading causes of death in the world, is a complex metabolic disorder due to genetic and environmental interactions. [21][22][23] Metabolomics, a powerful technical system that studies the entire metabolic pathway of a particular biological system. This technology has been increasingly used to identify metabolic biomarkers and improve clinical diagnosis and treatment of diseases. ...