William Thorburn's scientific contributions

Publications (6)

Article
Abstract The aim was to elucidate whether goniodysgenesis is more frequently observed in elderly patients with glaucoma, and furthermore, which signs of goniodysgenesis are of importance and most unanimously detected. Thus, 3 examiners evaluated 21 glaucoma patients and 19 non-glaucoma patients in a masked fashion. None of the patients had a First-...
Chapter
The aim was to elucidate if goniodysgenesis is more frequently observed in elderly patients with glaucoma, and furthermore what signs of dysgenesis are important and most unanimously detected. Thus, three observers evaluated dysgenesis of the anterior segment in a masked fashion in 21 glaucoma patients compared to those of 19 non-glaucoma patients....
Article
In a well defined population, the observed incidence of different types of glaucoma during the years 1980-82 is presented. The great majority of glaucoma patients was found to have primary open angle glaucoma, and of these approximately 3/4 had capsular glaucoma. The observed annual incidence of all types of glaucoma increases with increasing age t...
Article
In a well defined population, all patients with newly diagnosed primary open angle glaucoma were classified according to the degree of functional damage at diagnosis. A comparison was made between patients with simple and capsular glaucoma. No difference could be found between the 2 types of glaucoma when the severity of visual damage at diagnosis...
Article
During our studies on glaucoma we have made an important and surprising observation. We think it is urgent to report that we have found the survival time of glaucoma patients seems to be substantially shortened. To the best of our knowledge this has not been previously reported.
Article
In a region where both simple and capsular glaucoma are common, the observed prevalence of glaucoma with glaucomatous visual field defects based on hospital records is presented. The prevalence increased with increasing age to a maximum of 4.5% of the age group 81-85. Capsular glaucomas accounted for two thirds of the glaucomatous visual field defe...

Citations

... Traditionally, the patient's anterior chamber angle is assessed before and after laser peripheral iridotomy using gonioscope. 1 However, gonioscopic examination is associated with interobserver bias and does not estimate the angle accurately. 2 Ultrasound biomicroscopy (UBM) is an imaging modality that has near light microscopic precision for examination of anterior segment. Laser peripheral iridotomy (LPI) has replaced incisional iridectomy for most part, mainly due to its non-invasiveness and safety. ...
... 8 Studies have also shown that glaucomatous damage progresses more rapidly in patients with PXF and glaucoma when compared with those having chronic open-angle glaucoma. [9][10][11][12][13][14] Visual field defects have also been shown to be more severe at the time of diagnosis in patients with pseudoexfoliative glaucoma (PXG) 11,15 and to deteriorate more rapidly when compared with chronic open-angle glaucoma. 16 Cataracts have been reported to be more common in PXF patients, 17,18 and PXF has also been shown to be associated with zonulysis during cataract surgery as well as postoperative lens dislocation. ...
... Moreno-Montanes et al also found in their study PXE glaucoma was present in 44.5% of open angle glaucomas in Spain. According to them visual field loss was more in PXE glaucoma as compared to POAG.11 Various other studies show the prevalence of PXE glaucoma as 1.6 %, 5.2%,7.5% & 13% respectively 12-15 while the incidence of PXE glaucoma was as high as 50% of glaucoma patients in Sweden.16,17 The incidence of PXE glaucoma observed by Rashid W et al in their study was higher than any study done in India and this could be attributed to climatic or genetic factors. ...
... It has been suggested that in untreated glaucoma, blindness will occur in an average of 14.4 years with intraocular pressures (IOPs) between 21 and 25 mmHg, and 6.5 years for pressures between 25 and 30 mmHg. 1 Even on treatment, an estimated 9% of the patients will become bilaterally blind after 20 years of treatment. 2 Some studies have considered glaucoma and its relationship to shortened survival, [3][4][5][6][7] Others have considered the effects of systemic disease on glaucomatous progression. 8,9 These studies, however, do not consider poor life expectancy as a factor in glaucomatous progression. ...
... Yet, the effect of sex-specific risk factors in glaucoma is not often considered, likely because sex has not been unequivocally identified as a risk factor for glaucoma (Tielsch et al. 1990;Varma et al. 2004). For example, several studies have shown a higher prevalence of primary open-angle glaucoma (POAG) in males (Kim et al. 2016;Leske et al. 1994;Leibowitz et al. 1980), while others found higher rates in females (Lindblom and Thorburn 1982;Mason et al. 1989;Mitchell et al. 1996;Friedman et al. 2004). Yet other studies failed to find an association between sex and POAG (Hollows and Graham 1966;Klein et al. 1992;Tielsch et al. 1991;Wensor et al. 1998). ...