William Montagna’s research while affiliated with Mount Sinai Hospital and other places

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Publications (209)


Glycogen and lipids in human cartilage, with some cytochemical observations of the cartilage of the dog, cat, and rabbit
  • Article

February 2005

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6 Reads

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4 Citations

The Anatomical Record

William Montagna




Epidermis

January 1992

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17 Reads

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6 Citations

The epidermis, the outermost part of the skin, is a continually renewing, stratified, squamous epithelium which has remarkable biological properties. The epidermis was first described by Marcello Malpighi (1628–1694), who believed that it was a gelatinous membrane, and divided it into an inner layer of viable cells (now known as the stratum malpighii) and an outer one of anucleated horny cells (stratum corneum). Most of the cells in the epidermis are keratinocytes arranged in layers that represent different stages of their differentiation. The outer layer, the horny layer, is a layer of extraordinary properties, and functions as a barrier. It protects the body from the environment and helps maintain the internal milieu.


Hair and Hair Follicles

January 1992

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11 Reads

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3 Citations

It is fashionable to refer to man as a naked ape, meaning a hairless ape. This witty designation, however, is completely wrong, since we are certainly not hairless and we are not apes. We are abundantly supplied with hairs, but most of them are barely visible to the naked eye. Quantitatively, we probably have as many hairs in our skin as furry animals.




Blood Vessels

January 1992

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21 Reads

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2 Citations

The skin has a rich supply of blood and lymph vessels that are nutritive as well as important in the regulation of temperature and blood pressure. The kinds of cutaneous vascular beds present are determined by the kinds of skin they perfuse, the types and numbers of appendages present, and the thickness of the dermal and hypodermal layers. Everywhere on the human body skin is vascularized by vessels that greatly exceed the need for nutrition.


Age, sunlight, and facial skin: A histologic and quantitative study

December 1991

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73 Reads

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265 Citations

Journal of the American Academy of Dermatology

Quantitative methods were developed to assess the interrelation between age and sunlight on the facial skin of healthy women living in the same sunny area. The women were grouped into the following categories: young versus old and low versus high solar exposure. The features evaluated were perceived age, amount of facial wrinkling, skin color, and skin elasticity. A punch biopsy specimen of cheek skin was obtained and prepared histologically for evaluation of solar elastosis. The histologic examination was complemented by quantification of collagen and elastin by computer-assessed image analysis. Perceived age was estimated by untrained women viewing high quality photographs. As expected, those with greater sun exposure looked older and had more wrinkles, more severe elastosis, increased elastin, and decreased collagen.


Citations (74)


... Montagna, with a Ph.D in Zoology, was affiliated to the Brown University of Rhode Island in 1950s, and later at the Oregon Regional Primate Research Center. [22][23][24][25] Table 1 summarizes the histological data generated by Montagna and his colleagues on the Montgomery glands in adolescent girls and women. The merit in these studies [22][23][24] was, that the surgical specimens were collected few hours after accidental deaths of subjects, and can be assumed to be of normal configuration. ...

Reference:

Montgomery glands in the Areolar region -A clinical overview
Histology and cytochemistry of human skin. XXXV. The nipple and areola
  • Citing Article
  • July 1970

British Journal of Dermatology

... granulation tissue, and/or regression or progression of As the inflammatory process subsides the kerepithelium in the sinus. Increased lightness (pink, pale atinocytes in the area of inflammation are stimulated pink) or darkness (purplish, brown, or deep black) to proliferate; the number of keratinocytes increases, and decrease in colour diameter indicate improvement, they phagocytize more melanin granules and the skin increase in red colour saturation and diameter indicate becomes darker [19 ]. When acute inflammation subdeterioration. ...

Other Cells in the Epidermis
  • Citing Chapter
  • December 1974

... If possible, patients' ability to perspirate was investigated by quantification of pilocarpine-induced sweating on the forearms (in an area of 57 mm 2 ) using the Wescor 3700 device (Wescor, Logan, United States) and determination of palmar sweat duct densities via reflectance confocal laser-scanning microscopy with the VivaScope 1,500 (Caliber Imaging & Diagnostics, New York, United States), both as described before (Burger et al., 2014). The total number of sweat ducts is determined early in life, which means that the sweat gland density decreases with an increasing skin surface (adults have about 300-500/cm 2 , while newborns normally show more than 1,000/ cm 2 ; Montagna and Parakkal, 1974). ...

Eccrine Sweat Glands
  • Citing Chapter
  • December 1974

... Sebaceous glands are not a type of sweat gland but worth mentioning here since their secretions can impact the composition of sweat collected at the skin surface [25]. Sebaceous glands, first described by Eichorn in 1826 [26], are associated with hair follicles and present over much of the body surface but particularly the scalp, forehead, face, and anogenital area [26,27]. They are absent on the palms of hands and soles of the feet [26]. ...

Sebaceous Glands
  • Citing Chapter
  • December 1974

... The lack of consensus and sparse information on breast tissue material and mechanical properties may have contributed to the variability seen in the experimental methodologies, demographics, and specimens [14,15]. Breast tissue is located internally, whereas skin is the first layer, which is located externally [7,[16][17][18]. Breast stability and behavior are dependent on its internal mechanical properties and applied external forces. ...

1. An Introduction to Skin
  • Citing Chapter
  • December 1974

... In addition, a selective modulation of the regional cortical excitability, an enlargement of the receptive fields, and the effects of cortical deafferentation could be taken into account in an attempt to explain a C-LEP generator preservation or reorganization44454647 . Moreover, we could speculate about a strong C-LEP network stability in reason of an older phylogenetic origin [48], and a functional switch to a fixed " in-parallel " or " in-series " processing of nociceptive inputs [49]. The main limitations in our study are to be considered the small number of EEG channels we employed (since we were not able to use a full-EEG cap), and the non-homogeneous gender and age matching of our sample. ...

Cutaneous Innervation
  • Citing Chapter
  • December 1974

... Normal development and function of the sebaceous gland also appears to be very important for correct hair development and cycling. The hair follicle is considered as a miniorgan living in the context of the ''pilo-sebaceous'' unit, which is composed of hair follicle, sebaceous gland, and pilo-erector muscle (Montagna and Parakkal, 1974 ). Abnormal sebaceous gland function within this context has been clearly associated with hair loss in several animal models for alopecia (Gates and Karasek, 1965; Gates et al., 1969; Williams and Stenn, 1994; Stenn, 2001; Porter et al., 2002). ...

The Pilary Apparatus
  • Citing Chapter
  • December 1974