Wenyan Dong’s research while affiliated with Shanghai Jiao Tong University and other places

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Publications (1)


The experimental procedure.
The change of salivary cortisol in control and CPO groups during three sessions of the experiment. s1: before the training of the n-back task; s2: after the training of the n-back task; and s3: after the n-back and mental arithmetic task. Values represent the mean ± SEM. ∗p<0.05, paired two-tailed Student’s t-test was used. #p<0.05, unpaired two-tailed Student’s t-test was used.
The frontal alpha (7.5–12.5 Hz) and beta (12.5–30 Hz) activities (% of total 1–30 Hz spectrum power) in F3 (a) and (c) and F4 (b) and (d) during four 5-min stages of the experiment. Pretraining: before the n-back training task; posttraining: after the n-back training task; intervention: immediately after receiving CPO or control treatment; and posttask: after the mental arithmetic test task. Values represent the mean ± SEM. ∗p<0.05. Paired two-tailed Student’s t-test was used.
The frontal alpha (7.5–12.5 Hz) and beta (12.5–30 Hz) activities (% of total 1–30 Hz spectrum power) in F3 (a) and (c) and F4 (b) and (d) during four 5-min stages of the experiment. Pretraining: before the n-back training task; posttraining: after the n-back training task; intervention: immediately after receiving CPO or control treatment; and posttask: after the mental arithmetic test task. Values represent the mean ± SEM. ∗p<0.05. Paired two-tailed Student’s t-test was used.
The frontal alpha (7.5–12.5 Hz) and beta (12.5–30 Hz) activities (% of total 1–30 Hz spectrum power) in F3 (a) and (c) and F4 (b) and (d) during four 5-min stages of the experiment. Pretraining: before the n-back training task; posttraining: after the n-back training task; intervention: immediately after receiving CPO or control treatment; and posttask: after the mental arithmetic test task. Values represent the mean ± SEM. ∗p<0.05. Paired two-tailed Student’s t-test was used.

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The Effect of Copaiba Oil Odor on Anxiety Relief in Adults under Mental Workload: A Randomized Controlled Trial
  • Article
  • Full-text available

March 2022

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271 Reads

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8 Citations

Evidence-based Complementary and Alternative Medicine

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Jie Chen

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Wenyan Dong

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Lei Yao

Background: Aromatherapy has been proved to be effective in alleviating anxiety in practices and research. Recently, copaiba oil (CPO) is popular in the market and is recommended for anxiety relief in aromatherapy practice. However, relevant scientific research is still lacking. Methods: A randomized controlled trial was designed to evaluate the anxiety-relieving effect of CPO inhalation in 22 adults. Jojoba oil was used as the control treatment. N-back and mental arithmetic tasks were used as stress stimulation. CPO or control intervention was carried out after the n-back training phase. The State-Trait Anxiety Inventory (STAI), EEG activities, physiological indexes including heart rate (HR), blood pressure (BP), blood oxygen saturation, and salivary cortisol were assessed in different phases of the experimental process. Results: There was no significant difference in the change of HR and BP between the CPO and control groups before odor intervention. The S-AI scores of the CPO treated participants decreased after the n-back and mental arithmetic tests and were significantly lower than those of the participants who received control treatments. The HR and salivary cortisol of participants who received CPO intervention significantly decreased during the n-back and mental arithmetic tests. Furthermore, a remarkable decrease of beta wave activity was observed in the left midfrontal region (F3) when the participant received the CPO intervention. Conclusion: The study's findings supported that the CPO odor showed beneficial effects on alleviating anxiety based on several indicators in subjective, physiological, and EEG measurements.

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Citations (1)


... Therefore, fatigue and anxiety are conditions that an individual experiences almost simultaneously [17]. Confusion, fatigue, and addiction are characteristic adverse effects of anxiety pharmacotherapy; for this reason, the use of non-pharmacological alternatives, including inhalation and massage aromatherapy, has emerged as one of the promising therapeutic tools due to its low cost and fewer side effects [59]. ...

Reference:

Aromatherapy and Essential Oils: Holistic Strategies in Complementary and Alternative Medicine for Integral Wellbeing
The Effect of Copaiba Oil Odor on Anxiety Relief in Adults under Mental Workload: A Randomized Controlled Trial

Evidence-based Complementary and Alternative Medicine