Wen-jie Fan's scientific contributions

Publication (1)

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Long non-coding RNA CRNDE (CRNDE) recently emerged as a carcinogenic promoter in various cancers including medulloblastoma. However, the functions and molecular mechanisms of CRNDE to the acquired drug resistance of medulloblastoma are still unclear. The transcript levels of CRNDE were examined in four medulloblastoma cell lines exposed to cisplati...


... 24,61,62 Recently, the oncogenic roles of CRNDE via regulating miRNAs were also demonstrated in medulloblastoma, renal cell carcinoma, and prostate cancer. [63][64][65] The detailed mechanisms still need to be further explored. Taken together, these studies demonstrate that CRNDE promotes the initiation, progression, and chemoresistance of many solid tumors. ...