Wei Xue's research while affiliated with Hebei University of Technology and other places

Publications (6)

Article
Full-text available
In this study, we sequenced and characterized the complete mitochondrial genome (mitogenome) of Quasilineus sinicus Gibson, 1990 (Heteronemertea, Nemertea) using Illumina sequencing technology. The circular mitogenome was 16,358 bp in length and comprised 22 transfer RNA genes, 13 protein-coding genes, and two ribosomal RNA genes. Its overall base...
Article
Mitochondrial dynamics and bioenergetics are considered play pivotal roles in the maintenance of mitochondrial function and cell viability. During the widely distributed food contaminant 3-chlorpropane-1,2-diol (3-MCPD) induced nephrotoxicity, mitochondrial morphology and function were impaired, but the specific mechanism responsible for the proces...
Article
Full-text available
The complete mitochondrial genome of Sinularia penghuensis was sequenced and analyzed using next-generation sequencing. The present mitochondrial genome was 18730 bp in length, containing 14 protein-coding genes (PCGs) (cox1-cox3.nad1-nad6, nad4L, atp6, atp8, cytb, and MutS), two ribosomal RNA genes (rRNAs) (12S and 16S), and one transfer RNA gene...
Article
Full-text available
The complete mitochondrial genome of Sarcophyton trocheliophorum was completed using next-generation sequencing (NGS) method. The mitochondrial genome is a circular molecule of 18,508 bp in length, containing 14 protein-coding genes, two ribosomal RNA genes and one transfer RNA gene (Met-tRNA). The base composition is 30.45% A, 16.03% C, 19.13% G,...
Article
Apigenin (API) is a kind of important flavonoid present in temperate and tropical fruit and vegetables, especially the celery. It exerts anticancer, anti-bacterial, anti-viral, anti-inflammatory, anti-oxidation properties. In the present study, the mechanism of protective action of apigenin on 3-chloro-1, 2-propanediol (3-MCPD)-induced renal injury...
Article
Patulin (PAT) is a mycotoxin which frequently detected in moldy fruits and fruit products. This study investigated the protective role of glutathione (GSH), a antioxidant agent, against PAT induced cytotoxicity and its potential mechanisms in HEK293 cells. The obtained results showed that addition of GSH significantly reduced cell viability and apo...

Citations

... LKB1 also can inhibit cell growth through suppressing the anti-apoptotic factors, such as STAT3, JNK, KRAS, MAPK, cyclooxygenase-2, and c-myc [42, 59,60]. In recent studies, LKB1-AMPK is still the major signaling pathway to regulate cell apoptosis [61][62][63]. The role of LKB1 plays in epithelial polarity is associated with MARK/PAR1 and AMPK. ...
... So far, only six mitogenomes of genus Sinularia have been sequenced Chen et al. 2019;Shen et al. 2021); their mitogenome lengths ranged from 18,730 to 18,742 bp. In the present study, complete mitochondrial genome of S. humilis (GenBank no. ...
... The phylogenetic relationship of S. humilis among other species of Sinularia was inferred with a concatenated dataset including the 14 PCGs and two rRNAs using maximum-likelihood (ML). Sarcophyton trocheliophorum (MK994517) was used as an outgroup (Shen et al. 2019). The ML phylogenetic analysis was performed using MEGA X. ...
... • Restoration of renal tissue lesion in 3-monochloropropane-1,2-diol (3-MCPD) treatment group • Renoprotective effect by modulating oxidative phosphorylation especially up-regulated the expressions of ATP6 and ATP8, re-establishing mitochondrial membrane potential (MMP), relieving rise in Bax/Bcl2 ratio, reducing cytochrome C release, and inhibiting Caspase 9 and 3 activation. Zhong et al. (2018) No. ...
... GSH is a small endogenous thiol-containing molecule, and the GSH system is of great importance for maintaining redox homeostasis [34]. PAT toxicity has been reported to be related to inducing depletion of GSH [13]. PAT administration significantly (p < 0.05) reduced GSH level in hepatic tissue by a half compared to the control group, while GSH level in kidney decreased but did not reach a significant (p > 0.05) level (Figure 6a). ...