W.H. Li’s research while affiliated with The University of Texas Health Science Center at Houston and other places

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Publications (1)


Mathematical Model for Studying Genetic Variation in Terms of Restriction Endonucleases
  • Article

November 1979

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521 Reads

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11,633 Citations

Proceedings of the National Academy of Sciences

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W.H. Li

A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this model are presented for estimating the number of nucleotide substitutions between two populations or species. To express the degree of polymorphism in a population at the nucleotide level, a measure called "nucleotide diversity" is proposed.

Citations (1)


... Data analysis SRAP profile scoring of clearly visible amplified band was recorded as presence (1) and absence (0), the binary scored data was subjected to NTSYSpc version 2.02i to compute the similarity matrix based on the Dice coefficient (Rohlf 1990), also known as the similarity coefficient of (Nei and Li 1979). Clustering analysis was conducted using the unweighted pair-group method with arithmetic mean (UPGMA) to construct the dendrogram. ...

Reference:

Unravelling genetic and phenotypic variability in Agave amica across India using sequence-related amplified polymorphism (SRAP) markers
Mathematical Model for Studying Genetic Variation in Terms of Restriction Endonucleases
  • Citing Article
  • November 1979

Proceedings of the National Academy of Sciences