W Zhu’s scientific contributions

... Notably, a case of HPV-14 and -21-positive EV acanthoma arising in association with condyloma has been reported, highlighting the coexistence of condyloma with EV acanthoma and suggesting a link between HPV infection and the development of these skin lesions. The literature also discusses the utility of in situ hybridisation for detecting genital HPV types in solitary epidermolytic acanthomas, with findings indicating the absence of genital HPV types in these lesions [81][82][83]. This suggests that while HPV may be implicated in the pathogenesis of some acanthomas, its role is not ubiquitous across all types or locations of acanthoma. ...

Reference:

Human Papillomavirus-Associated Giant Clear Cell Acanthoma and Squamous Cell Carcinoma: A Rare Case Report and Literature Review