Vishal Srivastava’s scientific contributions

Achyrathes aspera is an important medicinal herb that grows as a weed across Nepal's tropical region. It is a member ofthe amaranthaceae family. Dattiwan in Nepali, Apamarg in Sanskrit, prickly chaff flower in English, and Naayuruvi inTamil are all names for this plant. Because of their safety and effectiveness, medicinal plants are used to treat a variety ofailments. Though practically all of its parts are employed in ancient systems of medicine, the seeds, roots, and shoots arethe most essential medicinal elements. Carbohydrates, protein, glycosides, alkaloids, tannins, saponins, flavonoids, lignin,and other chemical components are important. According to the review, a large number of phytochemical compounds havebeen identified from the plant, which include antiperiodic, diuretic, purgative, laxative, antiasthmatic, hepatoprotective,anti-allergic, and other essential therapeutic characteristics. The herb is used as an emenagogue, antiarthritic, antifertility,laxative, ecbolic, abentifacient, and anti-helminthic, aphrodisiac, antiviral, anti-plasmodic, and antihypertensive,anticoagulant, diuretic, and anti-tumor in indigenous medicine. Cough, renal dropsy, fistula, scrofula, skin rash, nasalinfection, chronic malaria, impotence, fever, asthma, piles, and snake bites are also treated with it. This herb has astringent,digestive, diuretic, laxative, purgative, and stomachic properties. The plant's juice is used to cure boils, diarrhoea, dysentery,haemorrhoids, rheumatic aches, itches, and skin eruptions. Metholic extraction offers higher yields than alcohol andpetroleum extraction.

ABSTRACT The main aim of this review article which is used for the treatment in onychomycosis which is skin disorder cause by the pathogens includes dermatophytes, Candida and non-dermatophytes. Nail lacquer is also applicable in improvement clinical efficacy and also proper the patients compliance, Preparation of nail lacquer by simple mixing non�volatile, gloss, smoothness to flow, drug diffusion studies drug content compliance. Nail Lacquer is used on fingernail, toenail of the human beings. Which is protect the nail but, nail plate but most significant in maximize the beauty, gloss, impart color. Nail Lacquer is mostly applicable for those drug which have poor bioavailability in oral formulation this techniques is used in maximize the topical bioavailability of drug across the nail