Vijay Mali’s scientific contributions

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Publications (3)


Figure 1. Effects of the cell-free lyophilized filtrate of LAB on the viability of HCT 115 cell line for various concentration by MTT assay Values are expressed as viability mean ratio ± SD*, n = 3. The viability study conducted by MTT assay on HCT 115 cell lines shows a decrease in percentage cell viability, an approximately around 40% in case of the Lp for its highest dose of 50 µg/ml and further, showing the strongest anti-proliferative activity as compared to control group. In the case of Lp, expect the dose of 10 µg/ml the other doses from 20 µg/ml to 50 µg/ml shows the anti-proliferative activity. Similarly, the cell viability results obtained in case of Lr and La are 74% and 88% on HCT 115 cell line for its highest dose of 50 µg/ml
PROFILING OF LACTOBACILLUS BY DIVERSE CYTOTOXIC PARAMETERS
  • Article
  • Full-text available

November 2022

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53 Reads

World Journal of Pharmaceutical Research

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Atharv Mali

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Vijay Mali

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Nita Pawar

The cytotoxicity studies of the nutraceutical products, especially the lactobacillus (LAB) formulation are gaining importance due to its industrial application. To support the claim MTT test was performed on three different strains of Lactobacillus i.e. Lp-Lactobacillus plantarum; Lr-Lactobacillus rhamnosus and La-Lactobacillus acidophilus. The viability study conducted by MTT assay on HCT 115 cell lines shows a decrease in percentage cell viability, an approximately around 40% in case of the Lp for its highest dose of 50 µg/ml and further, showing the strongest anti-proliferative activity as compared to control group. SHORT COMMUNICATION The pharmacology research, for the evaluation of the toxicity, is become vital in regards to the neutraceuticals products development 1-7. The cytotoxicity studies of the nutraceutical products, especially the lactobacillus (LAB) formulation is gaining importance due to its industrial application 11-12. The interaction of the probiotics cells with the living host cells may rarely precipitate toxicity 13-18. The interaction of the LAB in pathophysiological conditions such as cancer is gaining importance as an alternative source of functional food 14-16. To support the claim MTT test was performed on three different strains of Lactobacillus i.e. Lp-Lactobacillus plantarum; Lr-Lactobacillus rhamnosus and La-Lactobacillus acidophilus. The culture of Lp and La were discovered by our team from sheep milk and whole genome

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Banana fibers camouflaging as a gut worm in a 6-month-old infant

May 2020

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314 Reads

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19 Citations

Iberoamerican Journal of Medicine

Worm infestation issue is a common health condition observed mostly in Asian countries. The prevalence of worms in children is higher due to the habit of playing in mud or outdoors which is not found in the case of an infant. Very rarely worm infestation is observed in infants. There is a need for an investigation to be carried out for live worms in the stool. Sometimes the change in the diet of the infant, irregular bowel movements, and worm-like things in stool makes an alarming situation. We report the original case of a 6-month-old infant camouflaging for worm infestation due to the presence of the thread-like parasite in stool. The routine stool and chemical analysis of black thread thing from stool revealed solid diet fibers of banana and not any parasitic infection.

Citations (2)


... Gastric acid and bile salts can destroy probiotics, but enteric covering or microencapsulation can keep them safe until they reach the lower gut. Also, new methods, such as bioadhesive formulations or encapsulation in hydrogels, make it easier to control the release of probiotics and stick them to particular parts of the gastrointestinal system [26][27][28][29][30][31] . ...

Reference:

Probiotics Change the Microbiota: From the Lab to the Bedside
The Diverse Cytotoxicity Evaluation of Lactobacillus Discovered from Sheep Milk

Acta Scientific Pharmaceutical Sciences

... An important part of public health, environmental justice stresses the importance of eliminating these inequalities and guaranteeing everyone the chance to grow up in a safe and secure setting. This investigation illuminates the methods, ramifications, and avenues toward equitable health by delving into the complex connection between community health, environmental justice, and cancer prevention 33 . ...

Banana fibers camouflaging as a gut worm in a 6-month-old infant
  • Citing Article
  • May 2020

Iberoamerican Journal of Medicine