Valerie Johnson's research while affiliated with Michigan State University and other places

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Publications (5)

Intravenous Injection of Adipose‐Derived Mesenchymal Stromal Cells Benefits Gait and Inflammation in a Spontaneous Osteoarthritis Model
Article
  • Aug 2022
Osteoarthritis (OA) is a leading cause of morbidity among aging populations, yet symptom and/or disease‐modification remains elusive. Adipose‐derived mesenchymal stromal cells (adMSCs) have demonstrated immunomodulatory and anti‐inflammatory properties that may alleviate clinical signs and interrupt disease onset and progression. Indeed, multiple m...
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Figure 1. Schematic representation of the scoping literature process...
A summary of the identified literature on contaminants in NFS.
A Review of Northern Fur Seal (Callorhinus ursinus) Literature to Direct Future Health Monitoring Initiatives
Article
Full-text available
  • Jul 2022
Northern fur seals (Callorhinus ursinus, NFS) are a vulnerable species broadly distributed throughout the north Pacific. Although commercial hunting stopped in 1984, the population has continued to decline for unknown reasons. The goal of this scoping review was to synthesize and review 50 years of literature relevant to the health of NFS to inform...
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Establishing a reference interval for acute phase proteins, cytokines, antioxidants and commonly measured biochemical and hematologic parameters in the northern fur seal (Callorhinus ursinus)
Article
  • Oct 2021
Over the past several decades there has been a precipitous decline of northern fur seals (Callorhinus ursinus; NFS) at their breeding grounds on the Pribilof Islands in the Bering Sea. The cause of this decline is likely multifactorial and could include changes in environmental parameters, prey abundance and distribution as well as exposure to path...
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Pretreatment aerobic bacterial swab cultures to predict infection in acute open traumatic wounds: A prospective clinical study of 64 dogs
Article
  • Apr 2020
Objective To determine the value of initial aerobic bacterial cultures of acute open traumatic wounds to predict bacterial species in wounds that become infected. Study design Prospective clinical trial. Animals Sixty‐four dogs with naturally occurring acute cutaneous traumatic wounds (2017‐2018). Methods Initial swabs were taken from each wound...
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Citations

... Mobility assessments via treadmill-gait and voluntary weight-bearing systems were utilized to identify potential alterations in gait parameters given the unilateral removal of the IFP/SC. The changes in gait over time for stride length, stance, and propel were an expected function of growth between 3 and 7 months of age [47][48][49]. ...
Reference: Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs
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... The remaining 12 (23.1%) dogs were noted to have concurrent illnesses, such as mast cell tumor (n = 2), cutaneous hemangiosarcoma (1), fibroma (1), heartworm disease (1), ichthyosis (1), immune-mediated neuropathy (1), immune-mediated polyarthritis (1), metastatic apocrine gland anal sac adenocarcinoma (1), osteosarcoma (1), spinal empyema (1), and a stomach mass for which there was no histologic diagnosis (1). ...
Reference: Comparison of bacteriologic culture results for skin wound swabs and skin wound biopsy specimens
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... Many of these AMPs are of particular interest due to their activity against pathogens that are resistant to conventional antibiotics (12,22). The antimicrobial effects of human and equine platelet products and MSCs have been reported against bacteria such as E. coli, S. aureus, Klebsiella pneumonia, Streptococcus agalactiae, Enterococcus faecalis, and biofilm aggregates (18)(19)(20)(21)(23)(24)(25). Decreased bacterial growth was confirmed through various techniques, including colony-forming units per milliliter (CFU/mL), optical density (OD) absorbance measurements, minimum inhibitory concentration (MIC) dilutions, and radial diffusion agarose gel assays. ...
Reference: In vitro antimicrobial activity of equine platelet lysate and mesenchymal stromal cells against common clinical pathogens
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