U Bruns's scientific contributions
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Publications (2)
Severe ovarian hyperstimulation syndrome (OHSS) leads to changes in laboratory analyte concentrations. Whereas elevated aminotransferase
activity is often observed, a cholestatic course with hyperbilirubinaemia and icterus seldom occurs. In this report, the case
of a 33 year old patient with polycystic ovary syndrome (PCOS) is described who, after...
The Abbott Ultrasensitive II hTSH assay was evaluated in three European centres and its performance compared with its predecessor and with commercially available kits. A total of 408 individuals was included in the study (140 euthyroid, 116 hyperthyroid and 86 hypothyroid subjects, as well as 26 patients with non-thyroidal illness and 30 patients w...
Citations
... Il est bien connu qu'au travers des générations successives de dosage, les mesures de TSH (Thyroid-Stimulating Hormone) plasmatique ont gagné en sensibilité de manière considérable. Cependant, au cours de ces 20 dernières années, des variations significatives de sensibilité inter-et intra-immunoprocédures ont été décrites dans de nombreux articles [4, 6, 24, 40, 46, 47,57,68,69]. Dans cette revue, nous résumerons les connaissances actuelles sur l'activité immunologique de l'hormone, expliquerons les causes possibles des discordances dans da Immuno-analyse & Biologie spécialisée Des discordances au sein des immunodosages de la TSH ont été rapportées ces 20 dernières années. Mais, jusqu'à présent il était difficile de trouver une explication à ces observations au niveau moléculaire. ...
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... In addition, pregnancy and oral contraceptives are mainly characterized by cholestasis which is rarely seen in OHSS (Shimono et al., 1988). Only two observations of cholestasis were reported during OHSS (Nawroth et al., 1996;Midgley et al., 1999). ...
