Toufique Ahmed Qureshi’s research while affiliated with Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand and other places

In the present study, the hematological and serum biochemical parameters were determined to establish the reference values in the wild Indian blue peafowl (Pavo cristatus) of Thar (desert) region in the Sindh province of Pakistan. A total of 60 blood samples were collected from peafowl (30 males and 30 female) in months of March and April, 2015. The gender difference showed that RBC, MCV and MCH concentrations were significantly higher (P < 0.05) and the serum total protein and Mg concentrations were significantly lower (P < 0.05) in male compared to female peafowl. In conclusion, the present study provides base-line values for hematology and serum biochemistry of apparently healthy Indian adult blue peafowl of Thar and can be used as reference values to evaluate the health or diseased conditions in the same species.

Aim: The aim of this study was to evaluate the impact of therapeutic and high doses of florfenicol on kidney and liver functional indicators in goat species. Materials and Methods: Six mature, healthy goats (combine breed and sex) with average weight 25 kg were selected for this study. The therapeutic (20 mg/kg b.w.) and high doses (40 and 60 mg) of florfenicol were administered for 3 days with 24 h interval. Blood samples were collected at 0, 24, 48, 72, 96, and 120 h following the each administered dose. Results: The results showed that the therapeutic dose of florfenicol produced nonsignificant effect on serum urea, creatinine, total protein (TP), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT) and bilirubin on all timings, and increased (p0.05) the serum glutamic oxaloacetic transaminase (SGOT) and serum glutamate-pyruvate transaminase (SGPT) levels for 48 h. Whereas the high doses of florfenicol (40 and 60 mg) significantly altered the kidney and liver functional indicators in the blood. In contrast with control, the serum urea level was (p<0.01) increased at all timing points. Creatinine values were altered (p<0.01, <0.05) in increasing manner from 24 to 96 h. The high dose of 40 mg decreased the TP (p<0.05) for 72 h and 60 mg persisted same effect (p<0.01) up to 120 h. The indices of ALP, GGT, SGOT, and SGPT were raised (p<0.01, <0.05) at all timings. The bilirubin indexes also (p<0.05) elevated from 48 to 72. Conclusion: It was concluded that the high doses of florfenicol produced reversible dose-dependent effects on functional indicators of kidney and liver such as urea, creatinine, TP, ALP, SGOT, SGPT, GGT, and bilirubin.

The present study evaluated the effects of Selenium Yeast, (SY) on villi morphology in small intestine of young goats. Ten cross-bred goats of age 110-130 days and weighing 9.93 -10.71 kg, at the commencement of experiment, were used in present study. Animals were fed basal diet consisting of hay and concentrate. The concentrate (2 % BW) was provided into two equal portions at 0800 and 1700 h daily and the hay was fed at ad libitum. Water was provided at ad libitum. Animals were allocated into two dietary groups, consisting of basal diet (CON), or basal diet with Selenium Yeast, 0.3 mg/kg feed (SY). The results showed that the duodenal and jejunal masses (grams per kilogram empty body weight, g/kg EBW) in SY (3.2 ± 0.09 and 6.69 ± 0.17) increased significantly (P < 0.05) than in CON (2.88 ± 0.09 and 6.13 ± 0.26). Dietary treatments did not alter (P > 0.05) the lengths of intestine, duodenum, jejunum and ileum compared to CON. Mucosal weight (%) was higher (P < 0.05) in the duodenum (76.75 ± 0.68) and jejunum (76.3 ± 0.19) of SY goats than that of CON (73.53 ± 0.82 and 72.99 ± 0.85). In duodenum, the villus height (µm) increased (P < 0.05) in SY (559.98 ± 23.22) as compared to CON (468.32 ± 31.41). In jejunum, villus height and width increased (P < 0.05) in SY (578.06 ± 15.68 and 77.30 ± 2.56) compared to control (437.88 ± 29.12 and 63.84 ± 3.22). The improvement in villi dimensions (length and width) led to increase (P < 0.05) in villus surface area by 36.2 and 58.81 % in duodenum and jejunum of SY fed goats compared to that of CON. Dietary treatments did not alter villi morphology in ileum. It can be concluded from the present study that dietary SY supplementation produced positive effects on some villi morphological characteristics in both duodenum and jejunum of goats. © 2016, Pakistan Agricultural Scientists Forum. All rights reserved.

The present study assessed effects of high dosed long acting oxytetracycline (Oxy LA) on some haemotological indices in six goats. Each goat was intramuscularly administered with a high dose (30 mg/kg BW) of Oxy LA for the period of 07 days with an interval of 48 hours. The blood samples were taken at different time-points from 0-148 h after final dose of Oxy LA for the assessment of haemotological indices. The results showed that Oxy LA administration significantly decreased (p< 0.05) leucocytes count at various time points from 6 to 120 h and the decrease in leucocyte count was highly significant (P< 0.01) at 72 and 96 h post-administration. Oxy LA treatment caused significant decrease (P< 0.05) in the lymphocytes count (1000/cu.mm) at all observed time-points from 6 to 148 h and the decrease in lymphocyte count was highly significant (P< 0.01) at various time points from 12 to 120 h. Significant decrease in the RBC count (millions/cu.mm), haemoglobin concentration (g/dl) and packed cell volume (PCV, %) was recorded at 24, 120, 148 h (P< 0.05) and at 48, 72, 96 h (P< 0.01) after administration of high dosed Oxy LA. Maximum decrease in RBC count, haemoglobin level and PCV occurred at 72 h post-administration.