Tina Katharina Amann's research while affiliated with Hof University of Applied Sciences and other places

... 22 Additional evidence suggesting subtle pathophysiological differences between patients with ECH and CCH include differences in response to the same treatment, as seen in examples from clinical trials to date with lithium 26,27 (efficacious in CCH but not ECH) and galcanezumab 28,29 (efficacious in ECH but not CCH) in preventive treatment, as well as non-invasive vagus nerve stimulation for acute treatment (efficacious in ECH but not CCH). 30,31 However, some CH treatments, particularly acute treatments such as subcutaneous and intranasal triptans and oxygen are efficacious in both ECH and CCH, [32][33][34][35][36] although some studies have reported differences in the magnitude of response. 32,33,35 Treatments to interrupt cluster periods or reduce the frequency of attacks (i.e., preventive treatment) are generally based on recommendations from treatment guidelines. ...