Tilmann Graf's research while affiliated with Bielefeld University and other places

Publications (5)

Article
Full-text available
Die Komplikation einer Enzephalitis nach einer ChAdOx1 nCoV-19-Impfung ist auf der Basis vorliegender Daten sehr selten. Es finden sich Hinweise, dass das Risiko, eine postvakzinale Enzephalitis zu entwickeln, nach einer Impfung mit ChAdOx1 nCoV-19 leicht erhöht ist. Auch wenn bisher nur der zeitliche Zusammenhang zwischen Impfung und Enzephalitis...
Article
Full-text available
The global SARS-CoV-2 pandemic has contributed to more than 163 million confirmed infections and 3.3 million deaths worldwide. The severity of the pandemic has led to an unprecedented effort to develop multiple effective vaccines. Due to excellent safety and efficacy data from clinical trials, several vaccines were approved. We report a case series...

Citations

... Zuhorn et al. [9] recently reported on 3 cases of postvaccinal autoimmune encephalitis following ChAdOx1 nCov-19 vaccination. In their additional analysis of the publicly available database, they estimated the incidence of such a possible association to be 0.1 per 100,000 vaccinations for the ChAdOx1 nCov-19 and 0.04 per 100,000 vaccinations for the mRNA vaccine (Comirnaty) [9]. ...
... Among the COVID-19 vaccines, the AZD1222 vaccine, an adenovirus-based viral vector vaccine, is associated with a higher risk of developing post-vaccination encephalitis than the BNT162b2 vaccine, an mRNA vaccine (13). In fact, 19 of the 24 patients with MOGAD following COVID-19 vaccinations (79.2%) had been inoculated with AZD1222 vaccines, as shown in Table. ...
... In addition, due to partial thrombosis of the superior mesenteric artery causing bowel ischemia, we began the treatment of extensive portal vein thrombosis after the large ileal enterectomy. To manage VITT, treatments such as anticoagulation, high-dose intravenous immune globulin (IVIG), therapeutic plasma exchange (TPE), corticosteroids, rituximab, and eculizumab have been used [18,20,23,37,[44][45][46][47][48]. In addition, many patients received transfusions of supportive blood products such as platelets and fibrinogen concentrate or cryoprecipitate. ...