January 2022
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3 Reads
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6 Citations
SSRN Electronic Journal
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January 2022
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3 Reads
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6 Citations
SSRN Electronic Journal
... Indeed, PM2.5 has been demonstrated to inflict damage upon a multitude of bodily systems through the induction of oxidative stress, inflammation, and regulated cell death (including apoptosis, necroptosis, and pyroptosis) [65,66]. In recent years, an increasing number of studies have shown that PM2.5 affects respiratory health by inducing ferroptosis, which can result in conditions such as lung injury, lung toxicity, and pulmonary fibrosis [67][68][69]. Firstly, PM2.5 has been demonstrated to promote the ferroptosis and senescence of type II alveolar epithelial (AT2) cells, which represent the primary line of defense against a range of air pollutant particles. ...
January 2022
SSRN Electronic Journal