Tianhau Hou’s scientific contributions

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Publications (1)


PM2.5 Inhibits System Xc- Activity to Induce Ferroptosis by Activating the AMPK-Beclin1 Pathway in Acute Lung Injury
  • Article

January 2022

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3 Reads

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6 Citations

SSRN Electronic Journal

Kun Yan

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Tianhau Hou

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Laiyu Zhu

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[...]

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Liping Peng

Citations (1)


... Indeed, PM2.5 has been demonstrated to inflict damage upon a multitude of bodily systems through the induction of oxidative stress, inflammation, and regulated cell death (including apoptosis, necroptosis, and pyroptosis) [65,66]. In recent years, an increasing number of studies have shown that PM2.5 affects respiratory health by inducing ferroptosis, which can result in conditions such as lung injury, lung toxicity, and pulmonary fibrosis [67][68][69]. Firstly, PM2.5 has been demonstrated to promote the ferroptosis and senescence of type II alveolar epithelial (AT2) cells, which represent the primary line of defense against a range of air pollutant particles. ...

Reference:

Ferroptosis induced by environmental pollutants and its health implications
PM2.5 Inhibits System Xc- Activity to Induce Ferroptosis by Activating the AMPK-Beclin1 Pathway in Acute Lung Injury
  • Citing Article
  • January 2022

SSRN Electronic Journal