May 2025
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5 Reads
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May 2025
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5 Reads
April 2025
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51 Reads
How can systemic changes in the international financial architecture accelerate the world's transition to clean energy and address the urgent challenges of the polycrisis? Building on extensive conversations within the Beyond Bretton Woods network, we present a series of causal relationships to diagnose the impairment if not hijacking of modern capitalism. Based on recent discourse about planetary boundaries and on sound applications of economics, we then detail six high-impact recommendations whose time has come: placing ecocentrism at the center of international finance reform; implementing an instantaneous global carbon price; establishing a new debt restructuring mechanism; incorporating the polycrisis into monetary policy; designing a novel nature-based currency; and creating new global governance entities. We conclude with a brief discussion of the means by which civil society can be rallied in support of these systemic changes.
February 2025
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128 Reads
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2 Citations
Volumetric Bioprinting (VBP), enables to rapidly build complex, cell‐laden hydrogel constructs for tissue engineering and regenerative medicine. Light‐based tomographic manufacturing enables spatial‐selective polymerization of a bioresin, resulting in higher throughput and resolution than what is achieved using traditional techniques. However, methods for multi‐material printing are needed for broad VBP adoption and applicability. Although converging VBP with extrusion bioprinting in support baths offers a novel, promising solution, further knowledge on the engineering of hydrogels as light‐responsive, volumetrically printable baths is needed. Therefore, this study investigates the tuning of gelatin macromers, in particular leveraging the effect of molecular weight and degree of modification, to overcome these challenges, creating a library of materials for VBP and Embedded extrusion Volumetric Printing (EmVP). Bioresins with tunable printability and mechanical properties are produced, and a novel subset of gelatins and GelMA exhibiting stable shear‐yielding behavior offers a new, single‐component, ready‐to‐use suspension medium for in‐bath printing, which is stable over multiple hours without needing temperature control. As a proof‐of‐concept biological application, bioprinted gels are tested with insulin‐producing pancreatic cell lines for 21 days of culture. Leveraging a multi‐color printer, complex multi‐material and multi‐cellular geometries are produced, enhancing the accessibility of volumetric printing for advanced tissue models.
October 2024
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10 Reads
September 2024
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106 Reads
Volumetric Bioprinting (VBP), enables to rapidly build complex, cell-laden hydrogel constructs for tissue engineering and regenerative medicine. Light-based tomographic manufacturing enables spatial-selective polymerization of a bioresin, resulting in higher throughput and resolution than what achieved using traditional techniques. However, methods for multi-material printing are needed for a broad VBP adoption and applicability. Although converging VBP with extrusion bioprinting in support baths offers a novel, promising solution, further knowledge on the engineering of hydrogels as light-responsive, volumetrically printable baths is needed. Therefore, this study investigates the tuning of gelatin macromers, in particular leveraging the effect of molecular weight and degree of modification, to overcome these challenges, creating a library of materials for VBP and Embedded extrusion Volumetric Printing (EmVP). Bioresins with tunable printability and mechanical properties are produced, and a novel subset of gelatins and GelMA exhibiting stable shear-yielding behavior offers a new, single-component, ready-to-use suspension medium for in-bath printing, which is stable over multiple hours without needing temperature control. As proof-of-concept biological application, bioprinted gels are tested with insulin-producing pancreatic cell lines for 21 days of culture. Leveraging a multi-color printer, complex multi-material and multi-cellular geometries are produced, enhancing the accessibility of volumetric printing for advanced tissue models.
... Such a system, when effectively combined with wavelengthspecific photocrosslinking or photodegradation chemistries, can allow in situ photo-bioprinting or photodegradation of multimaterial constructs. [51,52] As a conceptual demonstration of synergistic multi-wavelength projection, we activated each laser wavelength in pulses synchronized with the image sequence displayed on the DMD (illustrated in Figure 8A). For instance, the images for the FaSt-Light and ETH logo were divided into three separate images and synchronized with laser activation at 405, 450, or 520 nm, respectively, to create multicolor image projections ( Figure 8B). ...
February 2025