Thérèse Leroux's research while affiliated with Université de Montréal and other places
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Publications (9)
The doctrine of informed consent is now recognized worldwide through several international guidelines and normative instruments. Based on respect for the dignity and autonomy of patients and research participants, it has been the subject of numerous publications for quite some time. In a globalized world where a variety of spiritualities and cultur...
Résumé
L'utilisation de sujets d'expérimentation humains et animaux dans le domaine biomédical est universellement acceptée. À défaut d'une telle méthode, dit-on, qu'adviendrait-il du progrès de la science et du soulagement des misères dans le monde? Quoi qu'il en soit, un fait demeure: l'expérimentation humaine et animale, de par sa nature même, a...
In Canada, bioethics dates back to 1976. Two remarks will facilitate readers’ understanding of this chapter. First, Canada is a federation in which health is a shared legislative jurisdiction. As far as the public health-care system is concerned, all Canadian provinces are governed by a federal law, the Canada Health Act (R.S.C., 1985, c.C-6). Howe...
Purpose: The research objectives of our health technology assessment were to evaluate the screening accuracy and clinical and cost-effectiveness of polymerase chain reaction (PCR) testing compared with conventional screening tests (i.e., chromogenic agar) and no screening for methicillin resistant Staphylococcus aureus (MRSA) in hospitalized patien...
Genetic information can be used to target interventions that improve health and prevent disease. Indeed, the results of population genomics research could be useful for public health and national pandemic plans. Yet, firm scientific evidence originating from such research and the indicators of the role of health determinants, gene-gene and gene-env...
Institutional Animal Care and Use Committee (IACUC) members were interviewed on various ethical matters, including ethics, animal ethics, science and ethics, and the use of animals in research, in order to explore their implicit ethical framework. The results revealed that IACUC members entertain rich and diverse beliefs about ethics, that are part...
Three Canadian institutional animal care and use committees were observed over a 1-year period to investigate animal ethical evaluation. While each protocol was evaluated, the observer collected information about the final decision, the type of protocol (research vs. teaching), and the category of invasiveness. The observer also wrote down verbatim...
Selon certains, la nanoscience sera à l'origine d'une troisième révolution techno-logique compte tenu de ses multiples possibilités d'application dans des domaines des plus variés 1 , notamment, aérospatial, électronique, énergétique, militaire et évi-demment, pharmaceutique 2 . Pour une, la nanomédecine qui correspond au « domaine consacré à la sa...
Citations
... Comprehensible language must be used to help ensure understanding. Information disclosed to PwDs may not be fully understood if the language used is too technical [18]. Furthermore, participants should not be overloaded with information or under-informed [19]. ...
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... Since this review was published, there have been a number of published studies indicating that PCR may be effective in further reducing MRSA prevalence. A new HTA from Canada [32], evaluating PCR for MRSA screening in hospitals, concluded that PCR demonstrated some advantage in clinical effectiveness (high screening test accuracy and lower colonization, infection and transmission rates) over chromogenic agar; however, it concluded that questions remain over cost-effectiveness. This finding has been reinforced in two recent studies published in this journal [33,34]. ...
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... When used in research, results from genetic tests like ES and GS accelerate the discovery of new genetic variants associated with ASD but are subject to more reporting challenges than clinical tests [8]. The preferences of research participants with regards to receiving their personal or their child's genetic results vary, where many are interested while some are not [9]. ...
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... Female, BALB/c, 6-week-old immunocompetent, euthymic, and hairless mice were purchased from Razi Institute (Razi Institute, Karaj, Iran) used in this study. The animal study procedure was performed according to (Houde et al. 2009). Each group of mice, including treated and control groups containing 4-5 mice with the average weight of 26 ± 0.15 g/ mouse. ...
... 1), and has its parallel in Swedish legislation [1] (Section 36 p. 2), that animal research is justified only if ethically approved by a competent authority. However, some animal research, such as observing wild animals from afar, is exempt from this requirement [8] (Chapter 2: Sections [17][18][19][20][21][22][23][24][25]. Pain, suffering, distress, or lasting harm that cannot be considered necessary is not permitted by the Directive (Article 24 p. 2a). ...
