Theodor Weber's research while affiliated with University of Turku and other places

... Besides mechanism and degree of the effect of macro-analyte in each PRL assay is not always exactly the same for the samples containing this molecule. Therefore, macroPRL related interaction is thought to be dependent on the immunoassay system used as well as the sample [10,11,19,20]. In a study by Byrne et al. [21] results of 317 hyperprolactinemic samples analysed for prolactin on Beckman DxI 800 were compared with those determined with the PEG screening technique on the Wallac AutoDELFIA. ...

... Using of DBS technology for the preparation and analysis of target antigens in dried blood spots by immunoassay for the purposes of medical and veterinary diagnostics was described earlier. [16][17][18][19][20][21] DBS cards of conventional format are manufactured with cellulose bres and samples are applied dropwise onto marked round parts of the card. Aer drying, the paper discs with applied sample are punched. ...

... Adding to the contention about further expansion of screening is debate about how to respond to technological advancement that makes it technically possible to screen for Fragile X (Bailey and Murray 2008; Coffee et al. 2009), lysosomal storage diseases (Li et al. 2004; Meikle et al. 2006), immune deficiencies (Cassol et al. 1994; Puck 2007), Duchenne muscular dystrophy (Parsons and Bradley 2008; van Ommen and Scheuerbrandt 1993) and other rare disorders (Röschinger et al. 2003). Differentials in the uptake of disorders into screening programmes are suggestive of discrepancies between screening criteria and a lack of international standardization (Tuuminen et al. 1994). The development of screening programmes and the differences that have evolved are the consequence of context-specific interpretations of and amendments to screening criteria (Clague and Thomas 2002; Padilla et al. 2010). ...

... The adaptation to HRP was attempted by Zapata and co-workers using 4-hydroxybenzoic acid (HBA) [5]. The oxidation products of 4-hydroxyphenylpropionic acid (pHPPA) [6], chavicol [7], Amplex red [8] and prochlorperazine [9] did not sensitize their fluorescence measurements in the corresponding experiment setup. The other common drawbacks of aforementioned fluorogenic substrates are their insufficient reaction rates, relatively low stability in air or toward H 2 O 2 in the absence of HRP, tending to cause strong background signals and poor water-solubility [10,11]. ...

... Bilirubin (171 µmol/L) có thể ảnh hưởng tới định lượng acetaminophen và vancomycin. Lipid máu tạo ra độ đục gây chênh lệch kết quả đo phổ và sắc kí, vì vậy cần bị loại bỏ thông qua li tâm siêu tốc; protein niệu có thể ảnh hưởng tới sự gắn của chất phân tích với kháng thể trong quy trình định lượng miễn dịch [16,24,25]. ...

... Zusätzlich konnten zu keinem Zeitpunkt IgM-Antikörper gegen Mycoplasma pneumoniae nachgewiesen werden. Diese Beobachtungen lassen eine Seropersistenz der IgAund IgG-Antikörper vermuten, welche für Mycoplasma pneumoniae bekannt ist [8]. ...