The Practice Committee of the American Society for Reproductive Medicine's research while affiliated with American Society for Reproductive Medicine and other places
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Publications (102)
This document reviews surgical options for achieving patency in obstructed fallopian tubes and the factors that must be considered when deciding between surgical repair and IVF. This document replaces the document of the same name, last published in 2012 (Fertil Steril 2012;97:539–45).
• •Fertility-preservation technologies are rapidly evolving with hope that new and refined techniques will emerge.
• •Patients facing treatments likely to impair reproductive function deserve prompt counseling regarding their options for fertility preservation and rapid referral to an appropriate program.
• •At the present time, embryo, oocyte, and...
Approximately 30% of women of reproductive age and 35% of men of reproductive age in the United States smoke cigarettes. Substantial harmful effects of cigarette smoke on fecundity and reproduction have become apparent but are not generally appreciated. This document replaces the 2008 ASRM Practice Committee document of the same name. (Fertil Steri...
• •Abnormal luteal function may occur as the result of a medical condition (e.g., elevated prolactin, abnormal thyroid function), and infertile women suspected of having one of these disorders (e.g., irregular menses, galactorrhea) should be evaluated and appropriately treated for identified conditions.
• •No diagnostic test for luteal phase insuff...
Women with endometriosis typically present with pelvic pain, infertility, or an adnexal mass, and may require surgery. Treatment of endometriosis in the setting of infertility raises a number of complex clinical questions that do not have simple answers. This document replaces the 2006 ASRM Practice Committee document of the same name. (Fertil Ster...
Advances in the treatment of male infertility now routinely allow men with obstructive azoospermia to have fertility treatment without microsurgical reconstruction. A variety of methods for retrieving sperm from men with obstructive azoospermia have been described. The goals of sperm retrieval are to obtain the best quality sperm possible, to retri...
Amenorrhea is the absence or abnormal cessation of the menses. Primary and secondary amenorrhea describe the occurrence of amenorrhea before and after menarche, respectively.
This educational bulletin provides background and tips on how to recognize quality trials and then focuses on evaluating the validity, importance, and relevance of clinical trial results.
This document will outline new delivery systems and contraceptive formulations, summarize recent advances in emergency contraception, and review the effects of hormonal contraception on cancer risks, cardiovascular disease, and bone.
Approximately 30% of reproductive age women and 35% of reproductive age men in the United States smoke cigarettes. Substantial harmful effects of cigarette smoke on fecundity and reproduction have become apparent but are not generally appreciated.
New Current Procedural Terminology (CPT) codes for 2004 have been adopted for utilization with assisted reproductive technologies. It is important for professionals in the field of assisted reproductive technology (ART) to become familiar with them prior to their implementation. This document replaces the July 2002 American Society for Reproductive...
Although guidelines for androgen replacement therapy for older men have been developed by several groups, the data to support treatment are based on the results of only a small number of clinical trials. It has not been definitively established that the decline in testosterone seen in most aging men results in an androgen deficient state with healt...
Amenorrhea is the absence or abnormal cessation of the menses. Primary and secondary amenorrhea describe the occurrence of amenorrhea before and after menarche, respectively.
Although guidelines for androgen replacement therapy for older men have been developed by several groups, the data to support treatment are based on the results of only a small number of clinical trials. It has not been definitively established that the decline in testosterone seen in most aging men results in an androgen deficient state with healt...
This educational bulletin provides background and tips on how to recognize quality trials and then focuses on evaluating the validity, importance, and relevance of clinical trial results.
New Current Procedural Terminology (CPT) codes for 2004 have been adopted for utilization with assisted reproductive technologies. It is important for professionals in the field of assisted reproductive technology (ART) to become familiar with them prior to their implementation. This document replaces the July 2002 American Society for Reproductive...
Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that assisted reproductive technology (ART) practitioners consider deferring donors who have recently received smallpox vaccine or contracted symptomatic vaccinia virus infection through close contact w...
Citations
... 2016.). CC is approved by the Food and Drug Administration (FDA) for treatment of ovulatory dysfunction in females desiring pregnancy and is included in the American Society Reproductive Medicine guidelines [78]. CC has not been submitted to the FDA for investigation of infertility or hypogonadism in men, and subsequently is not FDA-approved for these indications. ...
... Initial studies examining the effects of IVF found an increased risk of adverse outcomes in pregnancies conceived by IVF when compared to pregnancies conceived through natural conception. Initially, these complications were attributed to the increased risk of multiple gestation following ART [14][15][16]. These findings led to changes in guidelines and the implementation of strategies to reduce multiple pregnancies including blastocyst transfer and elective single embryo transfer [17]. ...
... In fact, the real incidence of OHSS is probably much higher since the symptoms of the mild form of OHSS are not typical and easy to be ignored or misdiagnosed. Although the moderate clinical manifestations of OHSS are mainly some digestive symptoms abdominal discomfort, nausea, vomiting, diarrhea), it can be a potentially life-threatening condition in its severe forms which include hepatorenal failure, acute respiratory distress syndrome, hemorrhage from ovarian rupture, thromboembolism and even death, resulting in hospitalization in 1.9% of case [3,4]. Some severe OHSS may even result in death. ...
... According to the American Society of Reproductive Medicine, FHA is responsible for 20-35% of secondary amenorrhea. 4 It is estimated that FHA effects about 1.62 million women between the ages of 18 and 44 years in the US and 17.4 million women worldwide. [5][6][7] The mechanism of FHA is due to suppression of gonadotropin releasing hormone (GnRH) in the hypothalamic-pituitary-ovarian axis resulting in low follicle stimulating hormone (FSH) and luteinizing hormone (LH) being released from the anterior pituitary. ...
... The importance of sperm DNA fragmentation to ART outcomes has been a well-debated topic, and although sperm DNA fragmentation has been associated with decreased rate of pregnancy in natural conception, IUI, and IVF and with increased rate of miscarriage [128], ASRM guidelines report insufficient evidence to verify the relationship between sperm DNA damage and ART outcomes. ASRM therefore recommends against the routine use of DNA integrity evaluation for infertility treatment, classifying DNA fragmentation testing as a Level C recommendation [82]. Given this potential relationship between ART outcomes and sperm DNA damage, several studies have explored the relationship between DNA fragmentation and paternal age, with most finding an increase in fragmentation with increasing age [46,63]. ...
... However, multiple pregnancy rates were not significantly different between groups receiving cleavage-stage embryos and blastocysts (20% for cleavage-stage versus 18% for blastocyst) in the current meta-analysis. In the studies that have reported the incidence of multiple pregnancy (three or more implanted embryos), the incidence in the groups receiving cleavage-stage embryos or blastocysts was not different.29 ...
... With this type, weight loss is accomplished primarily through dieting, fasting, and/or excessive exercise [1]. In the present study, AN patients were premenarchal (n = 8), or had either primary (failure of menarche by the age 15 years [20], n = 4) or secondary (absence of regular menstruation for 3 months with previously normal menstruation [20], n = 31, mean duration 10.0 ± 8.5 months) amenorrhea. A history of traumatic bone fracture during childhood or adolescence was reported in 14% (n = 6) in the AN group; however, none occurred during the period of losing weight. ...
... Ovarian hyperstimulation syndrome (OHSS) is a major complication of artificial reproduction technology (ART) treatments, which must be considered through careful risk assessment prior to and throughout ART treatments. Risk factors for OHSS include younger age, lower BMI, polycystic ovarian syndrome, previous episode of OHSS, increased number of follicles, increased number of retrieved oocytes, high absolute levels or rapidly rising levels of estradiol (E2), human chorionic gonadotropin (hCG) administration and pregnancy [1][2][3][4][5] . ...
... Miscarriage is the most common complication of pregnancy, occurring in 15%-25% of pregnancies. However, less than 5% of all couples will be confronted with recurrent miscarriages, which is a distinct disorder defined as two or more consecutive early fetal losses prior to the 20th week of gestation [1]. Recurrent miscarriages are a syndrome with a highly heterogeneous etiology. ...
... However, the authors observed a statistically significant difference in live birth rates after MTR (19%) vs. IVF (31%) (p = 0.007). Ectopic pregnancy and spontaneous abortion (SAB) rates after MTR were 10% and 15.7%, respectively [44,45]. Another study showed even higher pregnancy rates after Robot-assisted tubal reanastomosis. ...
