Tatsuro Miyake’s research while affiliated with Osaka Dental University and other places

... The risk for the development of second primary malignant neoplasms (SPMN) is estimated to be 3-7% per year, with a 20-year cumulative rate of 36% [91,92]. Other factors that are considered when determining follow-up intervals include alcohol/tobacco status at diagnosis, with the higher recurrence rates occurring in those with a combination of smoking and alcohol abuse (49%), followed by smoking alone or alcohol alone (13% each), tumor size, and histopathological grade [88,93]. ...

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Oral Complications from Oropharyngeal Cancer Therapy

... In addition, there were 12 (28.6%) studies from the WPR, which included Australia [24,64,[66][67][68]71], New Zealand [63,69,70], Japan [65,72], and Hong Kong [73]. There were also 11 (26.2%) ...

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A scoping review on early childhood caries and inequalities using the Sustainable Development Goal 10 framework

... Hasonló eredményeket tudomásunk szerint sem a hazai, sem a nemzetközi szakirodalomban nem közöltek. Vizsgálataink lényeges korlátja, hogy a teszthelyeken megjelenő betegektől az anamnézis felvétele során nem gyűjtöttünk adatokat sem az esetleges SARS-CoV-2 okozta megbetegedésük, sem a felvett oltások, sem az eredményeket feltételezhetően tovább módosító dohányzás [38] tekintetében. ...

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Epicutaneous tests with dental materials before and during COVID-19 pandemic in the Central Hungary region

... This induced antibodies against OxLDL, but also against PC and ameliorated atherosclerosis significantly [120]. In a recent paper, a nasal double DNA adjuvant system with PC-KLH induced IgM anti-PC and reduction in aortic atherosclerosis in apoE k/o mice [121]. Additionally, passive immunization by IgM anti-PC reduced atherosclerosis in apoE ko mice using a venous graft model and weekly intraperitoneal injections of anti-PC. ...

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Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

... Bronchoalveolar lavage fluid (BALF) was collected using 2 ml of PBS as described previously (22). Nasal wash was collected using 1 mL of PBS as described (23). Concentrations of anti-NP IgA or IgG1 in sera, BALF, or nasal wash were determined by ELISA using NP 13.6 -BSA as a coating antigen as described previously (24). ...

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Subcutaneous immunization with zymosan generates mucosal IgA-eliciting memory and protects mice from heterologous influenza virus infection

... Pre-emptive analgesia involves analgesic medication being administered prior to tissue injury, in other words before the reception, transmission, modulation, and nociception of the aggressive stimulus, the objective being to prevent hyperalgesia and the resulting pain-amplifying stimulus 11 . Pre-emptive analgesia has been used as an effective pain control method in pediatric surgeries, and acetaminophen is one of the most commonly used drugs for pre-emptive analgesia in pediatric patients 7,9,[12][13][14] . ...

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A Comparison of The Effects of Pre-Emptive and Intraoperative Intravenous Acetaminophen Administration on Pain Management After CircumcisionSünnet Ağrısı Kontrolünde Intravenöz Asetamınofenın Preemptıf ve Intraoperatıf Uygulamasının Karşılaştırılması

... Vaccines 2024, 12, 619 2 of 17 cavity, many studies focus on mucosal immune pathways [12][13][14], highlighting mucosal immunity as a promising approach for preventing Pg infections. This review delves into the three main factors (antigens, adjuvants, and immunization routes) involved in developing Pg vaccines, outlining the challenges encountered in research. ...

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Porphyromonas gingivalis Vaccine: Antigens and Mucosal Adjuvants

... In this regard, we have shown that a DNA plasmid expressing the Flt3 ligand (pFL) as a mucosal adjuvant preferentially increases CD8 + dendritic cells (DCs) in the mucosal tissues and subsequently elicits Ag-specific Th2-type mucosal immune responses mediated by IL-4, inducing the production of CD4 + T cells when mice were nasally immunized with a combination of ovalbumin (OVA) or bacterial Ag plus pFL [14,15]. Furthermore, we have shown that nasal administration of a double DNA adjuvant (dDA) consisting of CpG oligodeoxynucleotide 1826 (CpG ODN), a known inducer of Th1-type immune responses, in combination with pFL, elicits mucosal and systemic antibody (Ab) responses to OVA [16], pneumococcal surface protein A (PspA) [17], influenza virus hemagglutinin [18], and recombinant FimA (rFimA) [19], through DCs activation [20]. In addition, we previously have shown that nasal administration of rFimA, in combination with dDA, effectively reduced Pg infection in the respiratory tract; this efficacy was mediated by increased numbers of CD8 + and CD11b + DCs and balanced Th1-and Th2-type cytokine responses in the mucosal tissues [21]. ...

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Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivalis colonization: an in-vitro study

... To address this issue, various surface modifications are applied to Ti and its alloys to improve their biological activity. At present, these modifications include plasma spraying, ion implantation, chemical deposition, and micro-arc oxidation technology, which enhance the bioactivity of Ti by changing the chemical composition, roughness, and morphology of its surface [11][12][13][14][15][16][17]. Among these methods, treatment with a strong alkali solution has been widely investigated because of its operational convenience, practicality, and effectiveness [18,19]. ...

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Enhancement of In Vitro Bioactivity of One-Step Spark Plasma Sintered Porous Titanium by Alkali-Treatment

... Non-synonymous SNPs (ns SNPs) are present in coding region of genome which is frequently leads to alteration in amino acid residues of gene product. This single lost or additional nucleotide causes a frame shift mutation (30) . This effect changes the protein that is expressed, this possibly will cause a harmful mutation (31) . ...

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Computational Analysis Revealed Five Novel Mutations in Human IL2RG gene Related to X-SCID