Tao Bai's research while affiliated with Huazhong University of Science and Technology and other places

Publications (15)

Article
Objective: This study aimed to investigate whether perceived stress mediated the relationship between hope and anxiety/depression symptoms among patients with COVID-19 during the epidemic. In addition, the potential moderating effect of coping styles was examined. Methods: From February 26 to March 10, 2020, patients with COVID-19 were asked to...
Article
Full-text available
Background Intestinal fibrosis is the most common complication of inflammatory bowel disease; nevertheless, specific therapies are still unavailable. Resolvin D1 (RvD1), a typical endogenous ω-3 fatty acid-derived lipid mediator, has attracted wide attention due to its remarkable anti-fibrosis effects. However, the efficacy and mechanisms of RvD1 i...
Article
Backgrounds Recently, the Coronavirus Disease 2019 (COVID-19) has caused a global pandemic. Several studies indicate that the digestive system can also be affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, patients with digestive symptoms should have a capsule endoscopy (CE). Methods COVID-19 patients with gas...
Article
Background Although sleep disorder was thought as a risk factor for functional bowel disorders, its impact role in adolescents remains unknown and may deserve further attention. This study aimed to evaluate the relationship between different dimensions of self-reported sleep status and functional bowel disorders among high school graduates. Method...
Article
Full-text available
BACKGROUND The diagnostic efficacy of endoscopic ultrasound (EUS) elastography for alimentary tract diseases remains uncertain. The aim of this study was to evaluate the utility of EUS elastography in differential diagnosis between the 2 most common subepithelium tumors of the digestive tract - gastrointestinal stromal tumors (GISTs) and gastrointe...
Article
Full-text available
Background Non-specific ST-T segment changes are prevalent and are proven risk factors for early onset of cardiovascular diseases. They can increase all-cause mortality by 100∼200% and are candidate for early signs of cardiovascular changes. Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide and is one facet of a multisystem disease th...
Preprint
Full-text available
Background: Irritable bowel syndrome (IBS) is one of the most acommon functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits. Leading to significant negative effect on patients’ quality of life and huge financial burden to health system, the management of IBS is a great...
Preprint
Full-text available
Background: Corona virus infective disease 19 (COVID-19) is the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and spreads very rapidly, which become a worldwide public healthy crisis. Until now, there is no effective antivirus drugs or vaccines specifically used for its treatment. So it is urgent to discover efficie...
Article
Full-text available
Objective: The aim of this systematic review and meta-analysis is to calculate the pooled placebo response rate in patients with chronic constipation (CC) in randomized controlled trial (RCT) and its related factors. Method: This systematic review and meta-analysis will be conducted under the guidance of Cochrane Handbook. The inclusive and excl...
Preprint
Background: Irritable bowel syndrome (IBS) is one of the most acommon functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits. Leading to significant negative effect on patients’ quality of life and huge financial burden to health system, the management of IBS is a great...
Article
Zinc-α-2-glycoprotein (AZGP1), is a newly identified adipokine that is associated with lipid metabolism and vascular fibrosis. Although adipokines contribute to lipid dysfunction and its related diseases, including stroke and coronary heart disease (CHD) , the role of AZGP1 remains unclear. In this study, the role of AZGP1 in atherosclerosis and CH...
Preprint
Background Irritable bowel syndrome (IBS) is one of the most acommon functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits. Leading to significant negative effect on patients’ quality of life and huge financial burden to health system, the management of IBS is a great...

Citations

... [24] Endoscopic findings in patients with COVID-19 and upper GI complaints include gastric, duodenal, or esophageal ulcers, various patterns of inflammation, erosions, ecchymoses, or edema. [11,[24][25][26][27] One case report describes diffuse small intestinal mucosal sloughing, reminiscent of graft-versus-host disease, detected by capsule endoscopy. [28] However, a significant number of upper GI tract examinations are normal (29.9% in one series). ...
... Tam et al. found that nighttime sleep duration <7 h was an independent risk factor for constipation among elementary school children in Hong Kong (31). Some studies indicated that poor sleep increased the risk of functional constipation among college students (32,33). A study of functional GI disorders and sleep duration found that functional constipation was associated only with decreased sleep rather than other sleep disorders like drowsiness (34). ...
... Frontiers in Artificial Intelligence | www.frontiersin.org September 2021 | Volume 4 | Article 672050 3 patient has a preexisting disease (Azevedo et al., 2020;Zhou et al., 2020a;Williamson et al., 2020), such as CHD (Mai et al., 2020), hypertension (Itoh, 2020), and diabetes (Gupta et al., 2020b). Here, we divided 1,352 COVID-19 patients into seven groups: s/p stroke (23 survived and seven died), CHD (89, 11), chronic obstructive pulmonary disease (COPD) (12, 2), diabetes (155,21), hypertension (306, 45), malignant tumor (56, 15), and those without preexisting diseases (767, 60) according to their past medical history ( Figure 1C). ...
... Furthermore, our approach provides the largest set of pre-clinical candidates and FDA approved drugs with known safety pro les to be further investigated for COVID-19 treatment. In comparison to other studies which have used the old version of Connectivity Map 21,22 or the limited L1000 web interface 23, the novelty of our work is twofold: First, it provides the largest repertoire of drug repurposing candidates across available SARS-CoV-2, in vivo, and in vitro settings [R Shiny WebApp]. Second, it has identi ed drug candidates that interfere with ACE2 coexpressed signatures in SARS-CoV-2 infected settings. ...
... Importantly, there is a discrepancy in reported effects of AZGP1 on CVD between patients with and without chronic kidney disease (CKD). While higher AZGP1 levels were associated with reduced incidence of coronary heart disease and atherosclerosis in non-CKD patients (14,15), higher AZGP1 levels were shown to correlate positively with CVD in ESRD patients (16). It is therefore interesting, that so far, AZGP1 has not been investigated in the context of kidney transplantation. ...