Talitha Jesse's research while affiliated with California State University and other places

Publication (1)

Article
Full-text available
2‐Formylphenylboronic acid condenses with active methylene reagents like α‐amino esters, ketones, and lactams directly to give benzo‐fused 1‐hydroxy‐2,1‐azaborines in good yields within minutes under microwave‐accelerated conditions. The new stable boron heterocycles prepared to demonstrate this approach were characterized by NMR spectroscopy. Thre...

Citations

... The first synthesis of these structures was presented by Choi and Lim in 2015, when they reported a mild, onepot Horner-Wadsworth-Emmons olefination which led to an unexpected product, Ncarboxybenzyl-1-hydroxy-6-methoxy-2,1benzo[c]-1,2H-azaborine-3-carboxylate instead of target indole [6]. Most recently, de Lescura et al. [7] published a study of microwave assisted synthesis of polycyclic azaborines from 2-formylphenylboronic acids. In In our unpublished studies related to boronate amino acids, we have encountere unexpected reactions caused by the empty p-orbital of boron. ...