Takuya Osada’s scientific contributions

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Publications (1)

Figure 3. Comparison in blood velocity profile in femoral artery between PAD and non-PAD. The blood velocity in the femoral artery above the bifurcation monitored in B-mode was clearly different between the PAD-leg (a monophasic pattern with low resistance component) and the non-PAD-leg (normal triphasic pattern) at pre-exercise in the left panel. The upper panels are for the PAD-leg and the lower panels for the non-PAD-leg. The blood velocity profile showed the restricted blood flow due to increases in intramuscular pressure during muscle contraction (→), and hyperemic increasing blood flow during muscle relaxation (←). Marked higher blood velocity in the diastolic component was obviously seen in the PAD-leg than the non-PAD-leg at 30%MVC in the middle panel (note the higher scale on the vertical axis in the PAD-leg compared with the non-PAD-leg). The magnitude of the hyperemic state after the end of exercise was enhanced in the PAD-leg compared with the non-PAD-leg in the right panel. PAD: peripheral arterial disease, %MVC: percentage of maximum voluntary contraction. PowerLab data acquisition system (Chart v.4.2.3 software; AD Instruments, Sydney, Australia). Heart rate was measured using the beat-by-beat from continuous recording of the blood pressure wave. Leg vascular conductance was calculated as LBF divided by blood pressure (LBF/blood pressure) using the unit ml/min/mmHg.
Figure 5. Relationship between LBF and %MVC during exercise. There was a statistically significant (r = 0.999, P < 0.01 in black solid line) positive linear relationship between LBF and %MVC in the non-PAD-leg despite fewer sample, but no significance in the PAD-leg (r = 0.879, P = NS in dashed red line). The LBF at 50% MVC was not included because the whole exercise secession was not completed. LBF: leg blood flow, %MVC: percentage of maximum voluntary contraction, PAD: peripheral arterial disease.
A Case of Muscle Contraction-Induced Ischemic Limb Hyperemia in a Patient with Peripheral Arterial Disease during Incremental Repeat Isometric Knee Extensor Workloads
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January 2020

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World Journal of Cardiovascular Diseases

Takuya Osada
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