Takashi Murata's research while affiliated with University of Shizuoka and other places

Publications (4)

Article
We isolated a novel oxidized sorbicillin dimer (1) as yellowish amorphous powder from the fermentation broth of Trichoderma sp. USF-2690 strain isolated from a soil sample. The structure of the compound was determined by elucidation of spectroscopic evidence. The compound was revealed to possess a new carbon skeleton in the group of oxidized sorbic...
Article
Full-text available
In our screening program for antioxidants with DPPH radical scavenging activity, we isolated four yellowish compounds from the fermentation broth of Trichoderma sp. USF-2690 strain isolated from a soil sample: two were novel compounds designated bisorbicillinol (1) and demethyltrichodimerol (2), and two were known compounds bisvertinolone (3) and t...

Citations

... Trichodimerol, reported from T. longibrachiatum (Andrade et al. 1992), Penicillium chrysogenum , and Trichoderma USF-2690 strain (Abe et al. 1998a, b), prominently inhibits lipopolysaccharide-induced tumor necrosis factor-α production, thus potentially being a new lead for the treatment of septic shock (Mazzucco and Warr 1996). Derivatives of trichodimerol, demethyl trichodimerol (Abe et al. 1998a, b), bisorbibetanone (Abe et al. 1999) produced by Trichoderma USF-2690, bisorbicillinol (Abe et al. 1998a, b), bisorbibutenolide, and bisorbicillinolide (Abe et al. 1998a, b), are all found to be antioxidants (Reino et al. 2008). Hebbar and Lumsden (1998) showed that gliotoxin has antibacterial, antiviral, and immunosuppressive characteristics. ...
... DPPH, commonly used to represent total free radical scavenging capacity of non-enzyme antioxidants, was determined by the method of Abe et al. with a minor modification (Abe et al., 1998). The total volume of reaction fluid, containing 0.5 mM DPPH-anhydrous ethanol and 100 mM acetate buffer, with 0.1 mL of enzyme extract fluid, was 3.0 mL. ...
... The other isolated compounds were identified by comparing the spectroscopic data with those published in the literature, and included 5-demethylustilopyrone A (also named saturnispol H, 9) (Meng et al., 2018) and dihydrotrichodimer ether A (10) (Zhai et al., 2016), oxosorbicillinol (11) (Abe et al., 2000), bisvertinolone (12) (Trifonov et al., 1986), demethyltrichodimerol (13) (Abe et al., 1998a), trichodimerol (14) (Andrade et al., 1992), bisorbicillinol (15) (Abe et al., 1998a), bislongiquinolide (also named trichotetronine) (16) (Andrade et al., 1997;Shirota et al., 1997), and bisorbicillinolide (17) (Abe et al., 1998b). ...