Syed Morteza Abedi's research while affiliated with McMaster University and other places

Publications (5)

Article
Cylindromas are classified by the World Health Organization (WHO) under appendageal tumors with benign apocrine and/or eccrine differentiation. Cylindromas are rare neoplasms that can be either solitary or multiple, with the latter being more prone to malignant transformation. Multiple cylindromas are often seen in a genetic condition known as Broo...
Article
Full-text available
Lymphoepithelioma-like carcinoma of the skin (LELCS) is a rare and poorly differentiated variant of squamous cell carcinoma. The lesion is histologically identical to undifferentiated nasopharyngeal carcinoma (lymphoepithelioma), but with Epstein-Barr virus involvement documented rarely. The first case of LELCS was described in 1988 by Swanson et a...

Citations

... Syrindoig Eccrine Carcinoma (SEC) was originally described as eccrine epithelioma by Freeman and Winklemann in 1969 and has been reported in the literature with a variety of names: eccrine carcinoma, eccrine syringomatous carcinoma, and sclerosing sweat duct carcinoma. 1 Although it is referred to with a variety of names, they all allude to the same pathology, SEC. 2 Dermatologists are usually more familiar with this disease than otoloaryngologists and otologists. Therefore, because of this and the fact that it has a low incidence and non-specific symptoms, SEC poses a significant diagnostic challenge to the ear surgeon. ...
... 7 Las formas solitarias, al tener una presentación clínica poco característica, hay que diferenciarlas clínicamente del carcinoma basocelular, quiste epidérmico o espiradenoma, ya que estos dos los podemos localizar en piel cabelluda y pueden mostrar aspecto quístico o pseudoquístico. [8][9][10] Los cilindromas son en general benignos, pero pueden volverse malignos en algunas ocasiones. 1 Cuando estos tumores aparecen en el contexto de la cilindromatosis múltiple, se puede presentar el síndrome de Brooke-Spiegler, donde las lesiones presentan crecimiento rápido desde el inicio, con ulceración, dolor y crecimiento local que excede los 20 cm e incluso la posibilidad de metástasis. 1 La histopatología confirma el diagnóstico, en la cual se observa una neoformación dérmica, los cilíndromas demuestran islotes irregulares que comprenden células basaloides rodeadas por una cubierta hialina eosinofílica, un material hialino PAS+, tipo membrana, con un patrón de mosaico o de rompecabeza. ...
... The tumor was histologically identical with the nasopharyngeal lymphoepithelioma described by Regaud Reverchon [4] and Schminke [5] in 1921. Over the years, other anatomical locations of LELC have been reported, such as the oesophagus [6], larynx [7], lungs [8], stomach [9], thymus [10], trachea [11], bladder [12], ovary [13], cervix [14], skin [15] and thyroid [16]. Some anatomical sites and cases of LELC have been ...