Svitlana I Chepyshko’s research while affiliated with Bukovinian State Medical University and other places

Objective: The aim: To analyze the results of inflammatory and immunological parameters of the oral cavity after cystectomy with different methods of connecting the edges of the operated area. Patients and methods: Materials and methods: The research was conducted in 87 patients who sought surgical treatment of odontogenic cysts of the jaws. Patients were divided into groups depending on the method of wound closure after surgery. We analyzed the results of laboratory tests (leukocytes, ESR, IL-1β, IL-6, TNF-α, IL-8, NO synthase, MMP-9). Results: Results: The analysis of the effectiveness of using different methods of approximation of the oral mucosa wound on inflammatory and immunological pa¬rameters showed that when using welding of the edges of the operated area using the EKVZ-300 "Patonmed" apparatus, we get positive results of laboratory indicators of inflammatory markers faster (leukocyte counts are normal on day 30, ESR, IL-1β - on the 14th day, TNF-α - on the 7th day, IL-6, IL-8, NO synthase, MMP-9 - on the 30th day), that is, healing in such patients is faster than in patients with wound closure with classic suture material or laser. Conclusion: Conclusions: When comparing the methods of approximation of postoperative oral mucosa wounds by different methods, based on the results of these inflammatory and immunological parameters, the best results were obtained when using electric welding of tissues. Further research and use of the proposed method will facilitate and shorten the rehabilitation period of patients after surgery.

Goal. To evaluate the effectiveness of the proposed method of cystectomy using electric welding on the basis of the obtained clinical and biochemical parameters. Materials and methods. Cystectomy was performed in 87 patients: 20 patients – 1 control group (classical surgical method), 28 patients – 2 control groups (cystectomy using laser technology) and 39 patients – the main group (cystectomy using electric welding). Results. The use of electric welding technology during cystectomy allowed to reduce and facilitate the postoperative period in patients of the main group up to 5 days in contrast to patients in other groups, in which symptoms of inflammation and pain were observed up to 14 days. Conclusions. The use of electric welding of tissues during cystectomy in the oral cavity allowed to achieve sterility of the operated area, reduce the intervention time, and due to the absence of foreign bodies in the wound to reduce and facilitate postoperative rehabilitation of patients. Key words: odontogenic cyst, cystectomy, electric welding of tissues, postoperative complications.