Susan M. Rambaud's research while affiliated with University of Auckland and other places

Publication (1)

Article
Osteocalcin (the 6,000 dalton Mr gamma-carboxyglutamate-containing protein of bone) has been detected in acid extracts of bones of the extinct class of New Zealand ratite birds, the moas, using a radioimmunoassay for sheep osteocalcin. The immunoreactive osteocalcin of the extracts of two of these bones (the fibulae from two specimens of Pachyornis...

Citations

... [1,3,[10][11][12][13] Additionally, because of its close association with hydroxyapatite, size, and acidity, it has been hypothesized to persist into the deep time making it a prime target for paleontological and archaeological investigations. [14][15][16][17][18][19][20][21][22][23][24][25] It has also been a target for fossil remains because the N-terminal residues are variable providing greater phylogenetically informative sequences than other commonly preserved proteins in bone (e.g., collagen I). [18] It is a small protein (~5800 Da) with three vitamin K dependent γ-carboxylated glutamic acid residues (Gla) at positions 17, 21, and 24 [26] that allow for direct binding to calcium in hydroxyapatite. ...