Susan E. Little’s research while affiliated with Oklahoma State University and other places

... Dose dependent effects of oxytetracycline (OXY) have been reported by different researchers (Payne et al., 2002, Radwan et al., 1998Lappin, 2001). The therapeutic dose (20mg/kg BW) may results in recurrence of infection (Payne et al., 2002). ...

Reference:

Short Term Administration of High Dosed Long Acting Oxytetracycline Alters Serum Biochemical and Electrolyte Level in Goat

... 4 This increase is likely due to a combination of changes in climate, tick range expansions, habitat and land use changes, and host population dynamics. 5 United States tularemia incidence is highest in the central plains, likely due to the high prevalence of the lone star tick (Amblyomma americanum) and American dog tick (Dermacentor variabilis). 5 From 2011 to 2019, Kansas had the fourth highest incidence of tularemia, with 10 4,6 In 2022, Kansas had the highest incidence of human tularemia cases reported in the US, with 0.9 cases per 100,000 residents, followed by Nebraska (0.7) and Arkansas (0.5). 6 Although human cases of tularemia are reportable, tularemia is not reportable from animal species in Kansas, and the incidence in Kansas pets is unknown. ...

Reference:

Companion animal veterinary personnel have occupational risk for tularemia and One Health role for tularemia prevention in Kansas

... But in recent years, with the progress of molecular studies, scientists have established three genetically distinct species and named the tropical lineage as R. linnaei (Šlapeta et al. 2021, 2022), the temperate lineage as R. sanguineus sensu stricto (Nava et al. 2018;Dantas-Torres et al. 2022), and the southern European lineage as R. rutilus (Šlapeta et al. 2023). Since all three species occur in different countries of the northern hemisphere (Ghodrati et al. 2024;Myers et al. 2024) and Iran covers a wide geographical area with different climatic zones, further molecular studies are needed to identify the possible presence of different species in the R. sanguineus s.l. complex. ...

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Molecular detection of Hepatozoon canis (Apicomplexa: Hepatozoidae) in ticks collected from dogs in Kerman

... This gap in research hinders our understanding of the complex relationship between the gut microbiome and human health. Taking the sampling method into account when determining the composition and diversity of the gut microbiome is crucial [32]. ...

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Metagenomic analysis reveals the community composition of the microbiome in different segments of the digestive tract in donkeys and cows: implications for microbiome research

... This can, in part, be attributed to the continued biogeographical changes occurring across the US allowing its suitable habitat to expand and its activity time to lengthen [10]. In Oklahoma, A. americanum has displayed considerable changes in peak activity times in comparison to previous reports with active adults documented one month earlier than historical trends [11]. Some other studies have reported on outcomes of detailed sampling of tick populations, with summaries of phenology and documentation of range shifts [12,13], but very few have studied regions with emerging or growing populations of A. americanum. ...

Reference:

Modeling spatiotemporal dynamics of Amblyomma americanum questing activity in the central Great Plains

... The efficacy of FLU against other parasites on dogs, particularly those that act as vectors for other parasites and pathogens, has included sand flies (Phlebotomus spp. (Bongiorno et al., 2020;Gomez et al., 2018a) and Lutzomyia longipalpis) (Queiroga et al., 2020), triatomine insects (Triatoma infestans (Busselman et al., 2023;Loza et al., 2017;Rokhsar et al., 2023), T. brasiliensis (Queiroga et al., 2021;Rokhsar et al., 2023), (Busselman et al., 2023 T. gerstaeckeri (Busselman et al., 2023) and Rhodnius prolixus), and mosquitoes (Aedes aegypti) (Duncan et al., 2023;Evans et al., 2023). Oral FLU (25-56 mg/kg) can effectively treat sand flies (P. ...

Reference:

A systematic review of fluralaner as a treatment for ectoparasitic infections in mammalian species

... How BRBV is maintained in nature remains unknown, but serosurveillance studies have identified some mammalian species that are permissive to BRBV infection. Amblyomma americanum ticks are generalist, 3-host ticks that readily feed on a wide range of vertebrate host species (Ferreira et al., 2023;McClung and Little, 2023); therefore, many species are potentially exposed to BRBV or involved in its enzootic transmission. In northwestern Missouri, BRBV-neutralizing antibodies were detected in serum samples from domestic dogs (Canis lupus familiaris), Eastern cottontails (Sylvilagus floridanus), horses (Equus caballus), raccoons (Procyon lotor), and white-tailed deer (Odocoileus virginianus) (Jackson et al., 2019). ...

Reference:

Serosurveillance Identifies Bourbon Virus-Neutralizing Antibodies in Bobcats, Coyotes, and Red Foxes in Missouri

... The benefits of fostering and transporting dogs around the country or world for adoption are clear; however, the risks associated with pathogen relocation and transmission are often ignored or limited during rescue efforts. In 2021, an international working group noted the ongoing spread of parasites and vectors by relocating dogs and cats from distant sites [34,35]. The group provided specific recommendations to medical professionals regarding the importance of vector borne and zoonotic disease surveillance, as well as the need to diagnose and treat internal and external parasites when rehoming dogs [34]. ...

Reference:

A One Health Zoonotic Vector Borne Infectious Disease Family Outbreak Investigation

... sanguineus sensu stricto (s.s.) taxon includes what is commonly referred to as "temperate" lineage ticks (Nava et al., 2018). In North America there is no current consensus on a species nomenclature for the "tropical" lineage (Brophy et al., 2022;Grant et al., 2023), but the designation Rh. linnaei has been proposed in other parts of the world (Slapeta et al., 2021(Slapeta et al., , 2022. Thus, in this study we will refer to tick mitochondrial haplotypes as either belonging to the temperate or tropical lineage of Rh. sanguineus s.l., as in other recent studies from the US (Brophy et al., 2022;Grant et al., 2023). ...

Reference:

A mutation associated with resistance to synthetic pyrethroids is widespread in US populations of the tropical lineage of Rhipicephalus sanguineus s.l

... Several species of ticks specialize as parasites of domestic dogs, including both temperate and tropical Rhipicephalus species [1]. In the U.S., Rhipicephalus sanguineus carries multiple pathogens of veterinary importance as well as Rickettsia rickettsii, the species that causes Rocky Mountain Spotted fever (RMSF) in humans [2][3][4][5][6]. ...

Reference:

Optimal control of a tick population with a view to control of Rocky Mountain Spotted Fever